A simplified one-pot synthesis of 9-[(3-[18F]Fluoro-1-hydroxy-2-propoxy)methyl]guanine([ 18F]FHPG) and 9-(4-[18F]Fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG) for gene therapy

Nuclear Medicine and Biology

Volumn 28, Issue 7, 2001, Pages 875-883

  Shiue, Grace G ^a   Shiu, Chyng Yann ^a   Lee, Roland L ^a   MacDonald, Douglas ^a   Hustinx, Roland ^a   Eck, Stephen L ^a   Alavi, Abass A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

18F FHBG; 18F FHPG; Ganciclovir; Gene therapy; Penciclovir; Stability of 18F FHPG

Indexed keywords

9 (4 FLUORO 3 HYDROXYMETHYLBUTYL)GUANINE F 18; 9 [(3 FLUORO 1 HYDROXY 2 PROPOXY)METHYL]GUANINE F 18; GANCICLOVIR; GUANINE DERIVATIVE; HYDROCHLORIC ACID; KRYPTOFIX 2.2.2; N (4 ANISYLDIPHENYLMETHYL) 9 [[1 (4 ANISYLDIPHENYLMETHOXY) 3 TOLUENESULFONYLOXY 2 PROPOXY]METHYL]GUANINE; PENCICLOVIR; POTASSIUM FLUORIDE F 18; RADIOISOTOPE; THYMIDINE KINASE; UNCLASSIFIED DRUG;

ACIDITY; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DRUG PURIFICATION; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; GENE EXPRESSION; GENE THERAPY; GLIOMA CELL; HERPES SIMPLEX VIRUS 1; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH TEMPERATURE PROCEDURES; LOW TEMPERATURE PROCEDURES; NONHUMAN; PARTITION COEFFICIENT; POSITRON EMISSION TOMOGRAPHY;

CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GANCICLOVIR; GENE THERAPY; GENETIC VECTORS; GLIOMA; GUANINE; HERPESVIRUS 1, HUMAN; HUMANS; RADIOPHARMACEUTICALS; SPECTROPHOTOMETRY, ULTRAVIOLET; THYMIDYLATE SYNTHASE; TUMOR CELLS, CULTURED;

EID: 0034813752     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(01)00253-0     Document Type: Article

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