Synthesis and evaluation of cis-1-[4-(hydroxymethyl)-2-cyclopenten-1-yl]-5- [124I]iodouracil: A new potential PET imaging agent for HSV1-tk expression

Journal of Medicinal Chemistry

Volumn 50, Issue 24, 2007, Pages 6032-6038

  Ahn, Hyunseok ^a,b   Tae, Hyun Choi ^b   De Castro, Kathlia ^a   Kyo, Chul Lee ^b   Kim, Byoungsoo ^c   Byung, Seok Moon ^b   Su, Hee Hong ^b   Jong, Chan Lee ^b   Kwon, Soo Chun ^b   Gi, Jeong Cheon ^b   Sang, Moo Lim ^b   Gwang, Il An ^b   Rhee, Hakjune ^a  

^a Hanyang University   (South Korea)

^b Korea Institute of Radiation and Medical Science   (South Korea)

^c Choongwae Pharma Co   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

1 [4 (HYDROXYMETHYL) 2 CYCLOPENTEN 1 YL] 5 IODOURACIL I 124; 2',3' DIDEHYDRO 2',3' DIDEOXY 5 IODOURIDINE; GANCICLOVIR; NUCLEOSIDE ANALOG; ORGANOTIN COMPOUND; PALLADIUM; RADIOISOTOPE; THYMIDINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; CROSS COUPLING REACTION; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; DRUG TUMOR LEVEL; HERPES SIMPLEX VIRUS 1; IMAGE ANALYSIS; IN VITRO STUDY; ISOTOPE LABELING; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; QUANTUM YIELD; RADIOCHEMISTRY; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL LINE, TUMOR; HERPESVIRUS 1, HUMAN; IODINE RADIOISOTOPES; MICE; MICE, NUDE; MICROSOMES, LIVER; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; SERUM; THYMIDINE KINASE; TISSUE DISTRIBUTION; URIDINE;

EID: 37849009406     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm070791g     Document Type: Article

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