Biodistribution, PET, and radiation dosimetry estimates of HSV-tk gene expression imaging agent 1-(29-deoxy-29-18F-fluoro-β-D- arabinofuranosyl)-5-iodouracil in normal dogs

Journal of Nuclear Medicine

Volumn 48, Issue 4, 2007, Pages 655-660

  Nimmagadda, Sridhar ^a,b   Mangner, Thomas J ^a   Douglas, Kirk A ^a,b   Muzik, Otto ^a,b   Shields, Anthony F ^a,b,c  

^a WAYNE STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c KARMANOS CANCER INSTITUTE   (United States)

Author keywords

18F; FIAU; Gene expression imaging; Herpes simplex virus thymidine kinase; Metabolism

Indexed keywords

FIALURIDINE; FLUORODEOXYGLUCOSE F 18; DNA; DRUG DERIVATIVE; FLUORINE; THYMIDINE KINASE; URACIL ARABINOSIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; DOSIMETRY; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; GENE EXPRESSION; HERPES SIMPLEX VIRUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMAGING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; ANIMAL; GENE EXPRESSION REGULATION; GENE THERAPY; GENETICS; KINETICS; LIVER; METABOLISM; METHODOLOGY; RADIOMETRY; REPORTER GENE; TISSUE DISTRIBUTION;

ANIMALS; ARABINOFURANOSYLURACIL; DNA; DOGS; FLUORINE RADIOISOTOPES; GENE EXPRESSION REGULATION; GENE THERAPY; GENES, REPORTER; KINETICS; LIVER; POSITRON-EMISSION TOMOGRAPHY; RADIOMETRY; SIMPLEXVIRUS; THYMIDINE KINASE; TISSUE DISTRIBUTION;

EID: 34248529804     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.106.036830     Document Type: Article

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