Positron emission tomography imaging of cardiac reporter gene expression in living rats

Circulation

Volumn 106, Issue 2, 2002, Pages 180-183

  Wu, Joseph C ^a   Inubushi, Masayuki ^a   Sundaresan, Gobalakrishnan ^a   Schelbert, Heinrich R ^a   Gambhir, Sanjiv S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Gene therapy; Heart diseases; Imaging; Nuclear medicine; Viruses

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC IMAGING; GENE EXPRESSION REGULATION; GENE TRANSFER; HEART DISEASE; HEART MUSCLE CELL; MONITORING; NONHUMAN; NUCLEAR MEDICINE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROMOTER REGION; RADIATION MEASUREMENT; RAT; REPORTER GENE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TISSUE SPECIFICITY;

ADENOVIRIDAE; ANIMALS; CARDIOVASCULAR DISEASES; FEASIBILITY STUDIES; FLUORINE RADIOISOTOPES; GAMMA RAYS; GENE EXPRESSION; GENE THERAPY; GENES, REPORTER; GENETIC VECTORS; GUANINE; HEART; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY; THYMIDINE KINASE; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0037047039     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000023620.59633.53     Document Type: Article

References (9)

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7. Human pharmacokinetic and dosimetry studies of [(18)F]FHBG: A reporter probe for imaging herpes simplex virus type-1 thymidine kinase reporter gene expression
8. Uptake of radiolabeled 2′-fluoro-2′-deoxy-5-iodo-1-beta-D-arabinofuranosyluracil in cardiac cells after adenoviral transfer of the herpesvirus thymidine kinase gene: The cellular basis for cardiac gene imaging
9. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses