MicroPET imaging of Cre-loxP-mediated conditional activation of a herpes simplex virus type 1 thymidine kinase reporter gene

Gene Therapy

Volumn 11, Issue 7, 2004, Pages 609-618

  Sundaresan, G ^a   Paulmurugan, R ^a   Berger, F ^a   Stiles, B ^a   Nagayama, Y ^b   Wu, H ^a   Gambhir, S S ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c STANFORD UNIVERSITY   (United States)

Author keywords

Conditional gene activation deletion; Cre recombinase; Cre loxP system; Herpes simplex virus type 1 thymidine kinase; Noninvasive imaging; Positron emission tomography reporter gene

Indexed keywords

ADENOVIRUS VECTOR; ALBUMIN; BETA ACTIN; BETA GLOBIN; CRE RECOMBINASE; FLUORINE 18; GUANINE DERIVATIVE; IMMEDIATE EARLY PROTEIN; POLYADENYLIC ACID; THYMIDINE KINASE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; BIOACCUMULATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; GENE ACTIVATION; GENE EXPRESSION; GENE SILENCING; GENETIC RECOMBINATION; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IMAGING SYSTEM; IN VITRO STUDY; LIVER; MODULATION; MONITORING; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SILENT GENE; STATISTICAL ANALYSIS; TAIL; TRANSGENIC MOUSE; ULTRASOUND SCANNER; VALIDATION PROCESS; VIRAL GENE DELIVERY SYSTEM; VIRUS PLAQUE; WESTERN BLOTTING;

ADENOVIRIDAE; ANIMALS; CELL LINE; GENE DELETION; GENE EXPRESSION REGULATION; GENES, REPORTER; HERPESVIRUS 1, HUMAN; INTEGRASES; LIVER; MICE; MICE, TRANSGENIC; MODELS, ANIMAL; RATS; RECOMBINATION, GENETIC; THYMIDINE KINASE; TOMOGRAPHY, EMISSION-COMPUTED; TRANSDUCTION, GENETIC; VIRAL PROTEINS;

ADENOVIRIDAE; ANIMALIA; HUMAN HERPESVIRUS 1; MUS MUSCULUS; SIMPLEXVIRUS;

EID: 1842429022     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3302194     Document Type: Review

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