Size does matter! Label-free detection of small molecule-protein interaction

Analytical and Bioanalytical Chemistry

Volumn 406, Issue 17, 2014, Pages 4033-4051

  Fechner, Peter ^a   Bleher, Oliver ^b   Ewald, Melanie ^b   Freudenberger, Kathrin ^b   Furin, Dominik ^b   Hilbig, Urs ^b   Kolarov, Felix ^b   Krieg, Katrin ^b   Leidner, Lothar ^b   Markovic, Goran ^a   Proll, Günther ^a,b   Pröll, Florian ^a,b   Rau, Sabrina ^b   Riedt, Johannes ^b   Schwarz, Barbara ^b   Weber, Patricia ^b   Widmaier, Julia ^b  

^a Biametrics GmbH   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Biomolecular interaction; High throughput screening (HTS); Label free; Protein; Small molecule

Indexed keywords

CELL CULTURE; ELECTROPHORESIS; MOLECULES; X RAY DIFFRACTION;

ANALYTICAL METHOD; BIOMOLECULAR INTERACTIONS; HIGH-THROUGHPUT SCREENING; LABEL FREE; LABEL-FREE DETECTION; LABEL-FREE TECHNIQUES; NATURAL PROTEINS; SMALL MOLECULES;

PROTEINS;

ANIMALIA;

LIGAND; PROTEIN; PROTEIN BINDING;

ANIMAL; CHEMISTRY; GENETIC PROCEDURES; HUMAN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; X RAY DIFFRACTION;

ANIMALS; BIOSENSING TECHNIQUES; CHROMATOGRAPHY, LIQUID; HUMANS; LIGANDS; MASS SPECTROMETRY; PROTEIN BINDING; PROTEINS; X-RAY DIFFRACTION;

EID: 84903766690     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-014-7834-4     Document Type: Review

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