Crystallization of protein-ligand complexes

Acta Crystallographica Section D: Biological Crystallography

Volumn 63, Issue 1, 2006, Pages 72-79

  Hassell, Anne M ^a   An, Gang ^a   Bledsoe, Randy K ^a   Bynum, Jane M ^a   Carter III, H Luke ^a   Deng, Su Jun J ^a   Gampe, Robert T ^a   Grisard, Tamara E ^a   Madauss, Kevin P ^a   Nolte, Robert T ^a   Rocque, Warren J ^a   Wang, Liping ^a   Weaver, Kurt L ^a   Williams, Shawn P ^a   Wisely, G Bruce ^a   Xu, Robert ^a   Shewchuk, Lisa M ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Crystallization; Protein ligand complexes

Indexed keywords

ANDROGEN RECEPTOR; CARRIER PROTEIN; GLUCOCORTICOID RECEPTOR; LIGAND; LIPOSOME; MINERALOCORTICOID RECEPTOR; PROTEIN;

ANIMAL; BINDING SITE; CHEMISTRY; CONFERENCE PAPER; CONFORMATION; CRYSTALLIZATION; HUMAN; METHODOLOGY; MUTATION; TEMPERATURE; X RAY CRYSTALLOGRAPHY;

ANIMALS; BINDING SITES; CARRIER PROTEINS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; HUMANS; LIGANDS; LIPOSOMES; MOLECULAR CONFORMATION; MUTATION; PROTEINS; RECEPTORS, ANDROGEN; RECEPTORS, GLUCOCORTICOID; RECEPTORS, MINERALOCORTICOID; TEMPERATURE;

EID: 33846460839     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444906047020     Document Type: Conference Paper

References (14)

1. Bledsoe, R. K., Madauss, K. P., Holt, J. A., Apolito, C. J., Lambert, M. H., Pearce, K. H., Stanley, T. B., Stewart, E. L., Trump, R. P., Willson, T. M. & Williams, S. P. (2005). J. Biol. Chem. 280, 31283-31293.
2. Bledsoe, R. K., Montana, V. G., Stanley, T. B., Delves, C. J., Apolito, C. J., McKee, D. D., Consler, T. G., Parks, D. J., Stewart, E. L., Willson, T. M., Lambert, M. H., Moore, J. T., Pearce, K. H. & Xu, H. E. (2002). Cell, 110, 93-105.
3. Burley, S. K. (2004). Structure-Guided Drug Discovery Using Fragment-Based Lead Identification/Lead Optimization. Keystone Symposium on Structural Genomics, Snowbird, UT, USA.
4. Brzozowski, A. M., Pike, A. C. W., Dauter, Z., Hubbard, R. E., Bonn, T., Engstrom, O., Ohman, L., Greene, G. L., Gustafsson, J.-A. & Carlquist, M. (1997). Nature (London), 389, 753-758.
5. Hassell, A. M., Shewchuk, L. M., Holmes, W. D., Rocque, W., Veal, J., Walker, D., Montana, V. & Kuyper, L. (1998). American Crystallographic Association Meeting, P150. http://aca.hwi.buffalo.edu//ACA98/abstracts/text/ E0194.html
6. He, B., Gampe, R. T., Kole, A. J., Hnat, A. T., Stanley, T. B., An, G., Stewart, E. L., Kalman, R. I., Minges, J. T. & Wilson, E. M. (2004). Mol. Cell, 16, 425-438.
7. Lusty, C. (1999). J. Appl. Cryst. 32, 106-112.
8. Madauss, K. P., Deng, S. J., Austin, R. J. H., Lambert, M. H., McLay, I., Pritchard, J., Short, S. A., Stewart, E. L., Uings, I. J. & Williams, S. P. (2004). J. Med. Chem. 47, 3381-3387.
9. Matias, P. M., Donner, P., Coelho, R., Thomaz, M., Peixoto, C., Macedo, S., Otto, N., Joschko, S., Scholz, P., Wegg, A., Balser, S., Schafer, M., Egner, U. & Carrondo, M. A. (2000). J. Biol. Chem. 275, 26164-26171.
10. Sack, J. S., Kish, K. F., Wang, C., Attar, R. M., Kiefer, S. E., An, Y., Wu, G. Y., Scheffler, J. E., Salvati, M. E., Krystek, S. R. Jr, Weinmann, R. & Einspahr, H. M. (2001). Proc. Natl Acad. Sci. USA, 98, 4904-4909.
11. Skarzynski, T. & Thorpe, J. (2006). Acta Cryst. D62, 102-107.
12. Tanenbaum, D., Wang, Y., Williams, S. P. & Sigler, P. B. (1998). Proc. Natl Acad. Sci. USA, 95, 5998-6003.
13. Wang, L. & Nolte, R. T. (2006). In preparation.
14. Williams, S. P. & Sigler, P. B. (1998). Nature (London), 393, 392-396.