T-type voltage-gated calcium channels as targets for the development of novel pain therapies

British Journal of Pharmacology

Volumn 163, Issue 3, 2011, Pages 484-495

  Todorovic, Slobodan M ^a,b   Jevtovic Todorovic, Vesna ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

diabetes; dorsal horn; dorsal root ganglion; low threshold Ca 2+ channel; nociception; pain killers; thalamus

Indexed keywords

2 (4 CYCLOPROPYLPHENYL) N [1 [5 [(2,2,2 TRIFLUOROETHYL)OXO]PYRIDIN 2 YL]ETHYL]ACETAMIDE; 3,5 DICHLORO N [1 (2,2 DIMETHYL TETRAHYDRO PYRAN 4 YLMETHYL) 4 FLUORO PIPERIDIN 4 YLMETHYL]BENZAMIDE; 3BETA,5BETA,17BETA 3 HYDROXYQANDROSTANE 17 CARBONITRILE; 5,5' DITHIOBIS(2 NITROBENZOIC ACID); AMILORIDE; ANALGESIC AGENT; ANTISENSE OLIGONUCLEOTIDE; ARACHIDONIC ACID; ASCORBIC ACID; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL T TYPE; CYSTEINE; DIZOCILPINE MALEATE; EFONIDIPINE; ENDOCANNABINOID; ETHOSUXIMIDE; MIBEFRADIL; MORPHINE; NEUROLEPTIC AGENT; NITROUS OXIDE; NNC 550396; PACLITAXEL; PENFLUORIDOL; PIMOZIDE; STEROID; UNCLASSIFIED DRUG; VINCRISTINE;

ALLODYNIA; ANALGESIC ACTIVITY; CALCIUM TRANSPORT; CHRONIC PAIN; DIABETIC NEUROPATHY; DOSE RESPONSE; DRUG POTENCY; DRUG TARGETING; DRUG TOLERABILITY; HUMAN; HYPERALGESIA; LONG TERM POTENTIATION; MEMBRANE POTENTIAL; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; OXIDATION REDUCTION STATE; PAIN; PATCH CLAMP; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; REVIEW; SENSORY NERVE CELL; SPINAL CORD DORSAL HORN; SPINAL GANGLION; SYNAPTIC TRANSMISSION; THALAMUS; UPREGULATION;

ANALGESICS; ANIMALS; ARACHIDONIC ACID; CALCIUM CHANNELS, T-TYPE; DIABETIC NEPHROPATHIES; ENDOCANNABINOIDS; GANGLIA, SPINAL; GTP-BINDING PROTEINS; HUMANS; ION CHANNEL GATING; MOLECULAR TARGETED THERAPY; NEURALGIA; OXIDATION-REDUCTION; PAIN; PHOSPHORYLATION; POSTERIOR HORN CELLS; SENSORY RECEPTOR CELLS; THALAMUS;

EID: 79955896976     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01256.x     Document Type: Review

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