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Volumn 21, Issue 4, 2001, Pages 349-359
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WaterLOGSY as a method for primary NMR screening: Practical aspects and range of applicability
a b b a c |
Author keywords
Dissociation binding constant; Drug design; Magnetization tranfers; NMR screening; Protein ligand interactions; Water Ligand Observed via Gradient SpectroscopY; WaterLOGSY
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Indexed keywords
DNA FRAGMENT;
LIGAND;
PROTEIN;
RNA;
WATER;
ANALYSIS;
ARTICLE;
BINDING AFFINITY;
CHEMICAL INTERACTION;
COMBINATORIAL CHEMISTRY;
CONTROLLED STUDY;
DISSOCIATION CONSTANT;
DRUG DESIGN;
EXPERIMENT;
HUMAN;
MACROMOLECULE;
MAGNETISM;
NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;
PRIORITY JOURNAL;
SCREENING;
SENSITIVITY AND SPECIFICITY;
TECHNIQUE;
TIME;
TITRIMETRY;
BINDING, COMPETITIVE;
CDC2-CDC28 KINASES;
CHEMISTRY, PHARMACEUTICAL;
COMBINATORIAL CHEMISTRY TECHNIQUES;
CYCLIN A;
CYCLIN-DEPENDENT KINASE 2;
CYCLIN-DEPENDENT KINASES;
DRUG EVALUATION, PRECLINICAL;
GLUTATHIONE TRANSFERASE;
HUMANS;
LIGANDS;
NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR;
PROTEIN BINDING;
PROTEIN-SERINE-THREONINE KINASES;
SENSITIVITY AND SPECIFICITY;
STRUCTURE-ACTIVITY RELATIONSHIP;
TIME FACTORS;
WATER;
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EID: 0035692794
PISSN: 09252738
EISSN: None
Source Type: Journal
DOI: 10.1023/A:1013302231549 Document Type: Article |
Times cited : (485)
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References (54)
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