-
1
-
-
80051791267
-
-
L. Kuo (eds). Elsevier Amsterdam
-
Congreve M, Rich R, Myszka D, Figaroa F, Siegal G, Marshall F (2011) In: Kuo L (ed) Methods in enzymology, 493, fragment-based drug design- tools, practical approaches, and examples. Elsevier, Amsterdam
-
(2011)
Methods in Enzymology, 493, Fragment-based Drug Design- Tools, Practical Approaches, and Examples
-
-
Congreve, M.1
Rich, R.2
Myszka, D.3
Figaroa, F.4
Siegal, G.5
Marshall, F.6
-
2
-
-
80051800021
-
-
Kuo L (ed) Elsevier, Amsterdam
-
Giannetti M (2011) In: Kuo L (ed) Methods in enzymology, 493, fragment-based drug design- tools, practical approaches, and examples. Elsevier, Amsterdam
-
(2011)
Methods in Enzymology, 493, Fragment-based Drug Design- Tools, Practical Approaches, and Examples
-
-
Giannetti, M.1
-
4
-
-
77956622674
-
-
10.1021/ml900002k 1:CAS:528:DC%2BC3cXhs1agtbk%3D
-
I Navratilova AL Hopkins 2010 ACS Med Chem Lett 1 44 48 10.1021/ml900002k 1:CAS:528:DC%2BC3cXhs1agtbk%3D
-
(2010)
ACS Med Chem Lett
, vol.1
, pp. 44-48
-
-
Navratilova, I.1
Hopkins, A.L.2
-
6
-
-
42949178113
-
Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors
-
DOI 10.1016/j.bmcl.2008.03.056, PII S0960894X08003417
-
SS Antonysamy B Aubol J Blaney MF Browner AM Giannetti SF Harris N Hébert J Hendle S Hopkins E Jefferson C Kisinger V Leveque D Marciano E McGee I Nájera B Nolan M Tomimoto E Torres T Wright 2008 Biorg Med Chem Lett 18 2990 2995 10.1016/j.bmcl.2008.03.056 1:CAS:528:DC%2BD1cXlvVWjtr0%3D (Pubitemid 351608863)
-
(2008)
Bioorganic and Medicinal Chemistry Letters
, vol.18
, Issue.9
, pp. 2990-2995
-
-
Antonysamy, S.S.1
Aubol, B.2
Blaney, J.3
Browner, M.F.4
Giannetti, A.M.5
Harris, S.F.6
Hebert, N.7
Hendle, J.8
Hopkins, S.9
Jefferson, E.10
Kissinger, C.11
Leveque, V.12
Marciano, D.13
McGee, E.14
Najera, I.15
Nolan, B.16
Tomimoto, M.17
Torres, E.18
Wright, T.19
-
7
-
-
40049083268
-
Label-free primary screening and affinity ranking of fragment libraries using parallel analysis of protein panels
-
DOI 10.1177/1087057108314651
-
MD Hämäläinen A Zhukov M Ivarsson T Fex J Gottfries R Karlsson M Björsne 2008 J Biomol Screen 13 3 202 209 10.1177/ 1087057108314651 (Pubitemid 351322871)
-
(2008)
Journal of Biomolecular Screening
, vol.13
, Issue.3
, pp. 202-209
-
-
Hamalainen, M.D.1
Zhukov, A.2
Ivarsson, M.3
Fex, T.4
Gottfries, J.5
Karlsson, R.6
Bjorsne, M.7
-
8
-
-
45749114201
-
Identification of MMP-12 inhibitors by using biosensor-based screening of a fragment library
-
DOI 10.1021/jm8000289
-
H Nordström T Gossas M Hämäläinen P Källblad S Nyström H Wallberg UH Danielson 2008 J Med Chem 51 3449 3459 10.1021/jm8000289 (Pubitemid 351875001)
-
(2008)
Journal of Medicinal Chemistry
, vol.51
, Issue.12
, pp. 3449-3459
-
-
Nordstrom, H.1
Gossas, T.2
Hamalainen, M.3
Kallblad, P.4
Nystrom, S.5
Wallberg, H.6
Danielson, U.H.7
-
9
-
-
39149130730
-
Surface plasmon resonance based assay for the detection and characterization of promiscuous inhibitors
-
DOI 10.1021/jm700952v
-
AM Giannetti BD Koch MF Browner 2008 J Med Chem 51 574 580 10.1021/jm700952v 1:CAS:528:DC%2BD1cXjt1entg%3D%3D (Pubitemid 351252285)
-
(2008)
Journal of Medicinal Chemistry
, vol.51
, Issue.3
, pp. 574-580
-
-
Giannetti, A.M.1
Koch, B.D.2
Browner, M.F.3
-
10
-
-
3142781225
-
-
10.1038/nrd1343 1:CAS:528:DC%2BD2cXis1GktrY%3D
-
MR Arkin JA Wells 2004 Nat Rev Drug Discov 3 301 317 10.1038/nrd1343 1:CAS:528:DC%2BD2cXis1GktrY%3D
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 301-317
-
-
Arkin, M.R.1
Wells, J.A.2
-
11
-
-
33847381100
-
A decade of fragment-based drug design: Strategic advances and lessons learned
-
DOI 10.1038/nrd2220, PII NRD2220
-
PH Hajduk J Greer 2007 Nat Rev Drug Discov 6 211 219 10.1038/nrd2220 1:CAS:528:DC%2BD2sXit12rtr4%3D (Pubitemid 46344625)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.3
, pp. 211-219
-
-
Hajduk, P.J.1
Greer, J.2
-
12
-
-
77955863827
-
-
10.1021/jm100059d 1:CAS:528:DC%2BC3cXpsVChsb0%3D
-
CW Murray MG Carr O Callaghan G Chessari M Congreve S Cowan JE Coyle R Downham E Figueroa M Frederickson B Graham R McMenamin MA O'Brien S Patel TR Phillips G Williams AJ Woodhead A Woolford 2010 J Med Chem 53 5942 5955 10.1021/jm100059d 1:CAS:528:DC%2BC3cXpsVChsb0%3D
-
(2010)
J Med Chem
, vol.53
, pp. 5942-5955
-
-
Murray, C.W.1
Carr, M.G.2
Callaghan, O.3
Chessari, G.4
Congreve, M.5
Cowan, S.6
Coyle, J.E.7
Downham, R.8
Figueroa, E.9
Frederickson, M.10
Graham, B.11
McMenamin, R.12
O'Brien, M.A.13
Patel, S.14
Phillips, T.R.15
Williams, G.16
Woodhead, A.J.17
Woolford, A.18
-
14
-
-
84891584614
-
-
Wiley
-
Martin E, Wang J, Zaror I, Yu J, Yan K, Doyle M, Feucht P, Shoemaker K, Warne B, Chin M, Blisseth S, Leder L, Meyerhofer M, Wartchow C, Yao D (2011) In: Cooper M (ed) and Mayr LM (co-ed) Label-free technologies for drug discovery. Wiley
-
(2011)
Cooper M (Ed) and Mayr LM (Co-ed) Label-free Technologies for Drug Discovery
-
-
Martin, E.1
Wang, J.2
Zaror, I.3
Yu, J.4
Yan, K.5
Doyle, M.6
Feucht, P.7
Shoemaker, K.8
Warne, B.9
Chin, M.10
Blisseth, S.11
Leder, L.12
Meyerhofer, M.13
Wartchow, C.14
Yao, D.15
-
15
-
-
2542474493
-
Analysis of small-molecule interactions using Biacore S51 technology
-
DOI 10.1016/j.ab.2004.03.028, PII S000326970400260X
-
DG Myszka 2004 Anal Biochem 329 316 323 10.1016/j.ab.2004.03.028 1:CAS:528:DC%2BD2cXkt1Wqsrg%3D (Pubitemid 38680515)
-
(2004)
Analytical Biochemistry
, vol.329
, Issue.2
, pp. 316-323
-
-
Myszka, D.G.1
-
16
-
-
80051780864
-
-
St. Louis, Poster P2072
-
Wartchow C, Yao D, Li P, Heidecker B, Wei J, Choo S, Zuk R (2008) Society for Biochemical sciences annual meeting, St. Louis, Poster P2072
-
(2008)
Society for Biochemical Sciences Annual Meeting
-
-
Wartchow, C.1
Yao, D.2
Li, P.3
Heidecker, B.4
Wei, J.5
Choo, S.6
Zuk, R.7
-
17
-
-
33751119041
-
Comparative analysis of 10 small molecules binding to carbonic anhydrase II by different investigators using Biacore technology
-
DOI 10.1016/j.ab.2006.08.021, PII S000326970600621X
-
GA Papalia S Leavitt MA Bynum PS Katsamba R Wilton H Qiu M Steukers S Want L Bindu S Phogat AM Giannetti TE Ryan VA Pudlak K Matusiewicz KM Michelson A Nowakowski A Pham-Baginski J Brooks BC Tieman BD Bruce M Vaughn M Baksh YH Cho M De Wit A Smets J Vandersmissen L Michiels DG Myszka 2006 Anal Biochem 359 94 105 10.1016/j.ab.2006.08.021 1:CAS:528:DC%2BD28Xht1Sjs7jN (Pubitemid 44767842)
-
(2006)
Analytical Biochemistry
, vol.359
, Issue.1
, pp. 94-105
-
-
Papalia, G.A.1
Leavitt, S.2
Bynum, M.A.3
Katsamba, P.S.4
Wilton, R.5
Qiu, H.6
Steukers, M.7
Wang, S.8
Bindu, L.9
Phogat, S.10
Giannetti, A.M.11
Ryan, T.E.12
Pudlak, V.A.13
Matusiewicz, K.14
Michelson, K.M.15
Nowakowski, A.16
Pham-Baginski, A.17
Brooks, J.18
Tieman, B.C.19
Bruce, B.D.20
Vaughn, M.21
Baksh, M.22
Cho, Y.H.23
Wit, M.D.24
Smets, A.25
Vandersmissen, J.26
Michiels, L.27
Myszka, D.G.28
more..
-
18
-
-
80051780864
-
-
Phoenix, Poster B209
-
Podlaski F, Wartchow C, Gao L, Li S, Walker S, Ibabecki S, Huang K-S, Mark D (2010) Society for biochemical sciences annual meeting, Phoenix, Poster B209
-
(2010)
Society for Biochemical Sciences Annual Meeting
-
-
Podlaski, F.1
Wartchow, C.2
Gao, L.3
Li, S.4
Walker, S.5
Ibabecki, S.6
Huang, K.-S.7
Mark, D.8
-
19
-
-
80051780864
-
-
Phoenix, Poster B271
-
Wartchow C, Yao D, Chen J, Ho H, Ikin B, Perillat D, Wicke R, Witte, Zhao L-Z (2010) Society for biochemical sciences annual meeting, Phoenix, Poster B271
-
(2010)
Society for Biochemical Sciences Annual Meeting
-
-
Wartchow, C.1
Yao, D.2
Chen, J.3
Ho, H.4
Ikin, B.5
Perillat, D.6
Wicke, R.7
Witte8
Zhao, L.-Z.9
-
20
-
-
37549048249
-
-
10.1038/nrm2308 1:CAS:528:DC%2BD2sXhsVKrsrrP
-
RJ Youle A Strasser 2008 Nat Rev Mol Cell Biol 9 47 59 10.1038/nrm2308 1:CAS:528:DC%2BD2sXhsVKrsrrP
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
22
-
-
79955617610
-
-
10.1021/cb1002619 1:CAS:528:DC%2BC3MXnvVSltA%3D%3D
-
KM Comess C Sun C Abad-Zapatero ER Goedken RJ Gum DW Borhani M Argiriadi DR Groebe Y Jia JE Clampit DL Haasch HG Smith S Wang D Song ML Coen TE Cloutier H Tang X Cheng C Quinn B Liu Z Xin G Liu EH Fry V Stoll TI Ng D Banach D Marcotte DJ Burns DJ Calderwood PJ Hadjuk 2011 ACS Chem Biol 6 234 244 10.1021/cb1002619 1:CAS:528:DC%2BC3MXnvVSltA%3D%3D
-
(2011)
ACS Chem Biol
, vol.6
, pp. 234-244
-
-
Comess, K.M.1
Sun, C.2
Abad-Zapatero, C.3
Goedken, E.R.4
Gum, R.J.5
Borhani, D.W.6
Argiriadi, M.7
Groebe, D.R.8
Jia, Y.9
Clampit, J.E.10
Haasch, D.L.11
Smith, H.G.12
Wang, S.13
Song, D.14
Coen, M.L.15
Cloutier, T.E.16
Tang, H.17
Cheng, X.18
Quinn, C.19
Liu, B.20
Xin, Z.21
Liu, G.22
Fry, E.H.23
Stoll, V.24
Ng, T.I.25
Banach, D.26
Marcotte, D.27
Burns, D.J.28
Calderwood, D.J.29
Hadjuk, P.J.30
more..
-
23
-
-
0032917076
-
-
10.1110/ps.8.4.921 1:CAS:528:DyaK1MXisVWitr0%3D
-
D Beckett E Kovaleva J Schatz 1999 Prot Sci 8 4 921 929 10.1110/ps.8.4.921 1:CAS:528:DyaK1MXisVWitr0%3D
-
(1999)
Prot Sci
, vol.8
, Issue.4
, pp. 921-929
-
-
Beckett, D.1
Kovaleva, E.2
Schatz, J.3
-
24
-
-
77953356593
-
-
10.1016/j.ab.2010.03.044 1:CAS:528:DC%2BC3cXmvVWhsLk%3D
-
G Papalia D Myszka 2010 Anal Biochem 403 30 35 10.1016/j.ab.2010.03.044 1:CAS:528:DC%2BC3cXmvVWhsLk%3D
-
(2010)
Anal Biochem
, vol.403
, pp. 30-35
-
-
Papalia, G.1
Myszka, D.2
-
25
-
-
28544443984
-
Promoting apoptosis as a strategy for cancer drug discovery
-
DOI 10.1038/nrc1736
-
SW Fesik 2005 Nat Rev Cancer 5 876 885 10.1038/nrc1736 1:CAS:528:DC%2BD2MXht1Witb7J (Pubitemid 41746032)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.11
, pp. 876-885
-
-
Fesik, S.W.1
-
26
-
-
0035853130
-
Solution structure of the antiapoptotic protein bcl-2
-
DOI 10.1073/pnas.041619798
-
AM Petros A Medek DG Nettesheim DH Kim HS Yoon K Swift ED Matayoshi T Oltersdorf SW Fesik 2001 PNAS 98 6 3012 3017 10.1073/pnas.041619798 1:CAS:528:DC%2BD3MXit1amurY%3D (Pubitemid 32220791)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.6
, pp. 3012-3017
-
-
Petros, A.M.1
Medek, A.2
Nettesheim, D.G.3
Kim, D.H.4
Yoon, H.S.5
Swift, K.6
Matayoshi, E.D.7
Oltersdorf, T.8
Fesik, S.W.9
-
28
-
-
0036307897
-
Biophysical studies of eIF4E cap-binding protein: Recognition of mRNA 5′ cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins
-
DOI 10.1016/S0022-2836(02)00328-5
-
A Niedzwieka J Marcotrigiano J Stepinski M Jankowska-Anyszka A Wyslouch-Cieszynska M Dadlez A-C Gingras P Mak E Darzynkiewicz N Sonenberg SK Burley R Stolarski 2002 J Mol Biol 319 615 635 10.1016/S0022-2836(02)00328-5 (Pubitemid 34729439)
-
(2002)
Journal of Molecular Biology
, vol.319
, Issue.3
, pp. 615-635
-
-
Niedzwiecka, A.1
Marcotrigiano, J.2
Stepinski, J.3
Jankowska-Anyszka, M.4
Wyslouch-Cieszynska, A.5
Dadlez, M.6
Gingras, A.-C.7
Mak, P.8
Darzynkiewicz, E.9
Sonenberg, N.10
Burley, S.K.11
Stolarski, R.12
-
29
-
-
47749106894
-
Stoichiometry and physical chemistry of promiscuous aggregate-based inhibitors
-
DOI 10.1021/ja802977h
-
KED Coan BK Shoichet 2008 J Am Chem Soc 130 9606 9612 10.1021/ja802977h 1:CAS:528:DC%2BD1cXnvF2gsL8%3D (Pubitemid 352031174)
-
(2008)
Journal of the American Chemical Society
, vol.130
, Issue.29
, pp. 9606-9612
-
-
Coan, K.E.D.1
Shoichet, B.K.2
|