Cytotoxicity of water-soluble fraction from biodiesel and its diesel blends to human cell lines

Ecotoxicology and Environmental Safety

Volumn 74, Issue 8, 2011, Pages 2148-2155

  Leme, Daniela Morais ^a   Grummt, Tamara ^b   Heinze, Rita ^b   Sehr, Andrea ^b   Skerswetat, Matthias ^b   de Marchi, Mary Rosa Rodrigues ^a   Machado, Marcos Canto ^a   de Oliveira, Danielle Palma ^c   Marin Morales, Maria Aparecida ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b UMWELTBUNDESAMT   (Germany)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Apoptosis; Cell death process; Cell proliferation and viability; Necrosis; Polycyclic aromatic hydrocarbons

Indexed keywords

BIODIESEL; DIESEL FUEL; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; POLYCYCLIC AROMATIC HYDROCARBON; PROPIDIUM IODIDE; TETRAMETHYLRHODAMINE METHYL ESTER; TOXIC SUBSTANCE;

APOPTOSIS; BIOASSAY; CELL ORGANELLE; HEALTH RISK; OIL SPILL; PAH; POLLUTANT SOURCE; POLLUTION EFFECT; PUBLIC HEALTH; RISK FACTOR; TOXICITY; WATER POLLUTION;

APOPTOSIS; ARTICLE; CELL ASSAY; CELL DEATH; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ECOTOXICITY; ELECTROCHEMICAL ANALYSIS; HEALTH HAZARD; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; INDUSTRIAL WASTE; MITOCHONDRIAL MEMBRANE POTENTIAL; PETROCHEMICAL INDUSTRY; WATER CONTAMINATION;

BIOFUELS; CELL LINE; CYTOTOXINS; ENVIRONMENTAL POLLUTION; GASOLINE; HUMANS; SOLUBILITY; WATER POLLUTANTS, CHEMICAL;

ANIMALIA;

EID: 80755163206     PISSN: 01476513     EISSN: 10902414     Source Type: Journal    
DOI: 10.1016/j.ecoenv.2011.08.012     Document Type: Article

References (44)

1. Alkio M., Tabuchi T.M., Wang X., Colón-Carmona A. Stress responses to polycyclic aromatic hydrocarbons in arabidopsis include growth inhibition and hypersensitive response-like symptoms. J. Exp. Bot. 2005, 56:2983-2994.
2. Atadashi I.M., Aroua M.K., Aziz A.A. High quality biodiesel and its diesel engine application: a review. Renew. Sustain. Energy Rev. 2010, 14:1999-2008.
3. Babich H., Sardana M.K., Borenfreund E. Acute cytotoxicities of polynuclear aromatic hydrocarbons determined in vitro with the human liver tumor cell line, HepG2. Cell Biol. Toxicol. 1988, 4:295-309.
4. Blankenberg F.G. Imaging the molecular signatures of apoptosis and injury with radiolabeled annexin V. Proc. Am. Thorac. Soc. 2009, 6:469-476.
5. Castedo M., Ferri K., Roumier T., Métivier D., Zamzami N., Kroemer G. Quantitation of mitochondrial alterations associated with apoptosis. J. Immunol. Methods 2002, 265:39-47.
6. Demirbas A. Progress and recent trends in biodiesel fuels. Energy Convers. Manage. 2009, 50:14-34.
7. Donnelly K.C., Brown K.W., Anderson C.S., Barbee G.C., Safe S.H. Metabolism and bacterial mutagenicity of binary mixtures of benzo(a)pyrene and polychlorinated aromatic hydrocarbon. Environ. Mol. Mutagenesis 1990, 16:238-245.
8. Engeland M.V., Nieland L.J.W., Ramaekers F.C.S., Schutte B., Reutelingsperger C.P.M. Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure. Cytometry 1998, 31:1-9.
9. EPA (Environmental Protect Agency) Determination of polycyclic aromatic hydrocarbons in drinking water by liquid-solid extraction and hplc with coupled ultraviolet and fluorescence detection. Method 1990, 550:1.
10. EPA (Environmental Protect Agency), 2010. Renewable Fuel Standard Program (RFS2) Regulatory Impact Analysis. EPA-420-R-10-006. February, 2010.
11. Fernández-Álvarez P., Vila J., Garrido J.M., Grifoll M., Feijoo G., Lema J.M. Evaluation of biodiesel as bioremediation agent for the treatment of the shore affected by the heavy oil spill of the prestige. J. Hazard. Mater. 2007, 147:914-922.
12. Forsberg A.J., Kagan V.E., Schroit A.J. Thiol oxidation enforces phosphatidylserine externalization in apoptosis-sensitive and-resistant cells through a ΔΨm/cytochrome c release-dependent mechanism. Antioxid. Redox Signal. 2004, 6:203-208.
13. Franco R., Sánchez-Olea R., Reyes-Reyes E.M., Panayiotidis M.I. Environmental toxicity, oxidative stress and apoptosis: Ménage à Trois. Mutat. Res. 2009, 674:3-22.
14. Goldestein J.C., Waterhouse N.J., Juin P., Evan G.I., Green D.R. The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant. Nat. Cell Biol. 2000, 2:156-162.
15. Haşimoĝlu C., Ciniviz M., Özserta I., Içingü Y., Parlaka A., Salman M.S. Performance characteristics of a low heat rejection diesel engine operating with biodiesel. Renew. Energy 2008, 33:1709-1715.
16. Hiura T.S., Kaszubowski M.P., Li N., Nel A.E. Chemicals in diesel exhaust particles generate reactive oxygen radicals and induce apoptosis in macrophages. J. Immunol. 1999, 163:5582-5591.
17. Hiura T.S., Li N., Kaplan R., Horwits M., Seagrave J.-C., Nel A.E. The role of mitochondrial pathway in the induction of apoptosis by chemicals extracted from diesel exhaust particles. J. Immunol. 2000, 165:2703-2711.
18. He C., Ge Y., Tan J., You K., Han X., Wang J. Characteristics of polycyclic aromatic hydrocarbons emissions of diesel engine fueled with biodiesel and diesel. Fuel 2010, 89:2040-2046.
19. Hu Z., Tan P., Yan X., Lou D. Life cycle energy, environment and economic assessment of soybean-based biodiesel as an alternative automotive fuel in China. Energy 2008, 33:1654-1658.
20. Janaun J., Ellis N. Perspectives on biodiesel as a sustainable fuel. Renew. Sustain. Energy Rev. 2010, 14:1312-1320.
21. 2-CMX-Ros) and MitoTracker Red 580 (MTR580). J. Immunol. Methods 2005, 306:68-79.
22. Karavalakis G., Stournas S., Bakeas E. Effects of diesel/biodiesel blends on regulated and unregulated pollutants from a passenger vehicle operated over the European and the Athens driving cycles. Atmos. Environ. 2009, 43:1745-1752.
23. Keogh R.J. New technology for investigating trophoblast function. Placenta 2010, 31:347-350.
24. Marin-Morales M.A., Leme D.M., Mazzeo D.E.C. A review of the hazardous effects of polycyclic aromatic hydrocarbons on living organisms. Polycylic Aromatic Hydrocarbons: Pollution, Health and Chemistry 2009, 2-49. Nova Science Publishers Inc. P.A. Haines, M.D. Hendrickson (Eds.).
25. Miller N.J., Mudge S.M. The effect of biodiesel on the rate of removal and Weathering characteristics of crude oil within artificial sand columns. Spill Sci. Technol. B 1997, 4:17-33.
26. Mudge S.M., Pereira G. Stimulating the biodegradation of crude oil with biodiesel preliminary results. Spill Sci. Technol. B 1999, 5:353-355.
27. Mumtaz M.M., George J.D., Gold K.W., Cibulas W., DeRosa C.T. ATSDR evaluation of health effects of chemicals. IV. Polycyclic aromatic hydrocarbons (PAHs): understanding a complex problem. Toxicol. Ind. Health 1996, 12:742-971.
28. Nicodem D.E., Guedes C.L.B., Correa R.J. Photochemistry of petroleum. I. systematic study of Brazilian intermediate crude oil. Mar. Chem. 1998, 63:93-104.
29. Oris J.T., Giesy J.P. The photoenhanced toxicity of anthracene to juvenile sunfish (Lepomis spp.). Aquat. Toxicol. 1985, 6:133-146.
30. Pereira M.G., Mudge S.M. Cleaning oiled shores: laboratory experiments testing the potential use of vegetable oil biodiesels. Chemosphere 2004, 54:297-304.
31. Raynal P., Pollard H.B. Annexins: the problem of assessing the biological role for gene family of multifunctional calcium and phospholipid-binding proteins. Biochim. Biophys. Acta 1994, 1197:63-93.
32. Scaduto R.C., Grotyohann L.W. Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives. Biophys. J. 1999, 76:469-477.
33. Schmitz M., Boess F., Watzele M., Suter-Dick L., Roth A.B. In vitro assessments of hepatic toxicity using the xCELLigence real-time cell analyzer. Toxicol. Lett. 2009, 189S:S74-75.
34. Schirmer K., Dixon D.G., Greenberg B.M., Bols N.C. Ability of 16 priority PAHs to be directly cytotoxic to a cell line from the rainbow trout gill. Toxicology 1998, 127:129-141.
35. Seiler A., Lambernd S., Ehlich N., Ehlich A., Bohlen H., Watzele M. Monitoring of cardiac cytotoxicity in real-time with the xCELLigence system. Toxicol. Lett. 2009, 189S:S70.
36. Sgonc R., Gruber J. Apoptosis detection: an overview. Exp. Gerontol. 1998, 33:525-533.
37. Topinka J., Marvanová S., Vondrácek J., Sevastyanova O., Nováková Z., Krcm'r P., Pencíková K., Machala M. DNA adducts formation and induction of apoptosis in rat liver epithelial 'stem-like' cells exposed to carcinogenic polycyclic aromatic hydrocarbons. Mutat. Res. 2008, 638:122-132.
38. Urcan E., Haertel U., Styllou M., Hickel R., Scherthan H., Reichl F.X. Real-time xCELLigence impedance analysis of the cytotoxicity of dental composite components on human gingival fibroblasts. Dent Mater. 2010, 26:51-58.
39. Vanzella T.P., Martinez C.B.R., Cólus I.M.S. Genotoxic and mutagenic effects of diesel oil water soluble fraction on a neotropical fish species. Mutat. Res. 2007, 631:36-43.
40. Vermes I., Haanen C., Steffens-Nakken H., Reutelingsperger C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labeled annexin V. J. Immunol. Methods 1995, 184:39-51.
41. Waterhouse N.J., Goldestein J.C., von Ahsen O., Schuler M., Newmeyer D.D., Green D.R. Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process. J. Cell Biol. 2001, 53:319-328.
42. White P.A. The genotoxicity of priority polycyclic aromatic hydrocarbons in complex mixtures. Mutat. Res. 2002, 515:85-98.
43. Xia T., Korge P., Weiss J.N., Li N., Venkatesen M.I., Sioutas C., Nel A. Quinones and aromatic chemical compounds in particulate matter induce mitochondrial dysfunction: implications for ultrafine particle toxicity. Environ. Health Perspect. 2004, 12:1347-1358.
44. Yang H.-H., Chien S.-M., Lo M.-Y., Lan J.C.-W., Lu W.-C., Ku Y.-Y. Effects of biodiesel on emissions of regulated air pollutants and polycyclic aromatic hydrocarbons under engine durability testing. Atmos. Environ. 2007, 41:7232-7240.