Perspectives on zebrafish as a model in environmental toxicology

Fish Physiology

Volumn 29, Issue C, 2010, Pages 367-439

  Stegeman, John J ^a   Goldstone, Jared V ^a   Hahn, Mark E ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84901421880     PISSN: 15465098     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1546-5098(10)02910-9     Document Type: Chapter

References (323)

1. B.D. Adams H. Furneaux B. White The micro-RNA miR-206 targets the human estrogen receptor-{alpha}, and represses ER{alpha} mRNA and protein expression in breast cancer cell lines Mol. Endocrinol. 21 5 2007 1132 1147
2. D.V. Almeida B.F. da Silva Nornberg L.A. Geracitano D.M. Barros J.M. Monserrat L.F. Marins Induction of phase II enzymes and hsp70 genes by copper sulfate through the electrophile-responsive element (EpRE): Insights obtained from a transgenic zebrafish model carrying an orthologous EpRE sequence of mammalian origin Fish Physiol. Biochem. 2009 DOI 10.1007/s10695-008-9299-X.
3. S.L. Amacher Emerging gene knockout technology in zebrafish: Zinc-finger nucleases Brief Funct. Genomics Proteomics 7 6 2008 460 464
4. K. Amanuma H. Takeda H. Amanuma Y. Aoki Transgenic zebrafish for detecting mutations caused by compounds in aquatic environments Nat. Biotechnol. 18 1 2000 62 65
5. K. Amanuma S. Tone M. Nagaya M. Matsumoto T. Watanabe Y. Totsuka K. Wakabayashi Y. Aoki Mutagenicity of 2-[2-(acetylamino)-4-[bis(2-hydroxyethyl)amino]-5-methoxyphenyl]-5-amino-7-bromo-4-chloro-2H-benzotriazole (PBTA-6) and benzo[a]pyrene (BaP) in the gill and hepatopancreas of rpsL transgenic zebrafish Mutat. Res. 656 1-2 2008 36 43
6. K. Amanuma S. Tone H. Saito T. Shigeoka Y. Aoki Mutational spectra of benzo[a]pyrene and MeIQx in rpsL transgenic zebrafish embryos Mutat. Res. 513 1-2 2002 83 92
7. A. Amores A. Force Y.-L. Yan L. Joly C. Amemiya A. Fritz R.K. Ho J. Langeland V. Prince Y.-L. Wang Zebrafish hox clusters and vertebrate genome evolution Science 282 1998 1711 1714
8. E.A. Andreasen M.E. Hahn W. Heideman R.E. Peterson R.L. Tanguay The zebrafish (Danio rerio) aryl hydrocarbon receptor type 1 is a novel vertebrate receptor Mol. Pharmacol. 62 2 2002 234 249
9. E.A. Andreasen L.K. Mathew R.L. Tanguay Regenerative growth is impacted by TCDD: Gene expression analysis reveals extracellular matrix modulation Toxicol. Sci. 92 1 2006 254 269
10. E.A. Andreasen J.M. Spitsbergen R.L. Tanguay J.J. Stegeman W. Heideman R.E. Peterson Tissue-specific expression of AHR2, ARNT2, and CYP1A in zebrafish embryos and larvae: Effects of developmental stage and 2,3,7,8- tetrachlorodibenzo-p-dioxin exposure Toxicol. Sci. 68 2 2002 403 419
11. G.T. Ankley D.C. Bencic M.S. Breen T.W. Collette R.B. Conolly N.D. Denslow S.W. Edwards D.R. Ekman N. Garcia-Reyero K.M. Jensen Endocrine disrupting chemicals in fish: Developing exposure indicators and predictive models of effects based on mechanism of action Aquat. Toxicol. 92 3 2009 168 178
12. T. Annilo Z.Q. Chen S. Shulenin J. Costantino L. Thomas H. Lou S. Stefanov M. Dean Evolution of the vertebrate ABC gene family: Analysis of gene birth and death Genomics 88 1 2006 1 11
13. D.S. Antkiewicz R.E. Peterson W. Heideman Blocking expression of AHR2 and ARNT1 in zebrafish larvae protects against cardiac toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin Toxicol. Sci. 94 1 2006 175 182
14. M.D. Anway A.S. Cupp M. Uzumcu M.K. Skinner Epigenetic transgenerational actions of endocrine disruptors and male fertility Science 308 5727 2005 1466 1469
15. M.E. Baker B. Ruggeri L.J. Sprague C. Eckhardt-Ludka J. Lapira I. Wick L. Soverchia M. Ubaldi A.M. Polzonetti-Magni D. Vidal-Dorsch Analysis of endocrine disruption in Southern California coastal fish using an aquatic multispecies microarray Environ. Health Perspect. 117 2 2009 223 230
16. P.L. Bardet B. Horard M. Robinson-Rechavi V. Laudet J.M. Vanacker Characterization of oestrogen receptors in zebrafish ( Danio rerio ) J. Mol. Endocrinol. 28 3 2002 153 163
17. V. Begay J. Falcon G.M. Cahill D.C. Klein S.L. Coon Transcripts encoding two melatonin synthesis enzymes in the teleost pineal organ: Circadian regulation in pike and zebrafish, but not in trout Endocrinology 139 3 1998 905 912
18. S.M. Bello D.G. Franks J.J. Stegeman M.E. Hahn Acquired resistance to aryl hydrocarbon receptor agonists in a population of Fundulus heteroclitus from a marine superfund site: In vivo and in vitro studies on the induction of xenobiotic-metabolizing enzymes Toxicol. Sci. 60 1 2001 77 91
19. V. Bemanian R. Male A. Goksoyr The aryl hydrocarbon receptor-mediated disruption of vitellogenin synthesis in the fish liver: Cross-talk between AHR- and ERalpha-signalling pathways Comp. Hepatol. 3 1 2004 2
20. D.R. Bentley S. Balasubramanian H.P. Swerdlow G.P. Smith J. Milton C.G. Brown K.P. Hall D.J. Evers C.L. Barnes H.R. Bignell Accurate whole human genome sequencing using reversible terminator chemistry Nature 456 7218 2008 53 59
21. S. Bertrand B. Thisse R. Tavares L. Sachs A. Chaumot P.L. Bardet H. Escriva M. Duffraisse O. Marchand R. Safi Unexpected novel relational links uncovered by extensive developmental profiling of nuclear receptor expression PLoS Genet. 3 11 2007 e188
22. S.M. Billiard A.R. Timme-Laragy D.M. Wassenberg C. Cockman R.T. Di Giulio The role of the aryl hydrocarbon receptor pathway in mediating synergistic developmental toxicity of polycyclic aromatic hydrocarbons to zebrafish Toxicol. Sci. 92 2 2006 526 536
23. S.R. Blechinger R.C. Kusch K. Haugo C. Matz D.P. Chivers P.H. Krone Brief embryonic cadmium exposure induces a stress response and cell death in the developing olfactory system followed by long-term olfactory deficits in juvenile zebrafish Toxicol. Appl. Pharmacol. 224 1 2007 72 80
24. J.E. Bohonowych B. Zhao A. Timme-Laragy D. Jung R.T. Di Giulio M.S. Denison Newspapers and newspaper ink contain agonists for the ah receptor Toxicol. Sci. 102 2 2008 278 290
25. J.L. Bolton M.A. Trush T.M. Penning G. Dryhurst T.J. Monks Role of quinones in toxicology Chem. Res. Toxicol. 13 3 2000 135 160
26. A. Bosio E. Binczek M.M. Le Beau A.A. Fernald W. Stoffel The human gene CGT encoding the UDP-galactose ceramide galactosyl transferase (cerebroside synthase): Cloning, characterization, and assignment to human chromosome 4, band q26 Genomics 34 1 1996 69 75
27. T. Braunbeck M. Boettcher H. Hollert T. Kosmehl E. Lammer E. Leist M. Rudolf N. Seitz Towards an alternative for the acute fish LC(50) test in chemical assessment: The fish embryo toxicity test goes multi-species -- an update Altex 22 2 2005 87 102
28. A. Bresell R. Weinander G. Lundqvist H. Raza M. Shimoji T.H. Sun L. Balk R. Wiklund J. Eriksson C. Jansson Bioinformatic and enzymatic characterization of the MAPEG superfamily FEBS J. 272 7 2005 1688 1703
29. T. Bresolin M. de Freitas Rebelo A. Celso Dias Bainy Expression of PXR, CYP3A and MDR1 genes in liver of zebrafish Comp. Biochem. Physiol. C Toxicol. Pharmacol. 140 3-4 2005 403 407
30. K.G. Burnett L.J. Bain W.S. Baldwin G.V. Callard S. Cohen R.T. Di Giulio D.H. Evans M. Gomez-Chiarri M.E. Hahn C.A. Hoover Fundulus as the premier teleost model in environmental biology: Opportunities for new insights using genomics Comp. Biochem. Physiol. Part D Genomics Proteomics 2 4 2007 257 286
31. C.G. Burns D.J. Milan E.J. Grande W. Rottbauer C.A. MacRae M.C. Fishman High-throughput assay for small molecules that modulate zebrafish embryonic heart rate Nat. Chem. Biol. 1 5 2005 263 264
32. N. Bushati S.M. Cohen microRNA functions Annu. Rev. Cell Dev. Biol. 23 2007 175 205
33. S.M. Cantrell L.H. Lutz D.E. Tillitt M. Hannink Embryotoxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): The embryonic vasculature is a physiological target for TCDD-induced DNA damage and apoptotic cell death in Medaka ( Orizias latipes ) Toxicol. Appl. Pharmacol. 141 1996 23 34
34. G. Carlsson L. Norrgren Synthetic musk toxicity to early life stages of zebrafish (Danio rerio) Arch. Environ. Contam. Toxicol. 46 1 2004 102 105
35. S.A. Carney J. Chen C.G. Burns K.M. Xiong R.E. Peterson W. Heideman Aryl hydrocarbon receptor activation produces heart-specific transcriptional and toxic responses in developing zebrafish Mol. Pharmacol. 70 2 2006 549 561
36. S.A. Carney R.E. Peterson W. Heideman 2,3,7,8-Tetrachlorodibenzo-p-dioxin activation of the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator pathway causes developmental toxicity through a CYP1A-independent mechanism in zebrafish Mol. Pharmacol. 66 3 2004 512 521
37. S.A. Carney A.L. Prasch W. Heideman R.E. Peterson Understanding dioxin developmental toxicity using the zebrafish model Birth Defects Res. A Clin. Mol. Teratol. 76 1 2006 7 18
38. R. Carson Silent Spring 1962 Houghton Mifflin Boston
39. M.J. Carvan III D.M. Sonntag C.B. Cmar R.S. Cook M.A. Curran G.L. Miller Oxidative stress in zebrafish cells: Potential utility of transgenic zebrafish as a deployable sentinel for site hazard ranking Sci. Total Environ. 274 1-3 2001 183 196
40. M.J. Carvan 3rd T.P. Dalton G.W. Stuart D.W. Nebert Transgenic zebrafish as sentinels for aquatic pollution Ann. N. Y. Acad. Sci. 919 2000 133 147
41. M.J. Carvan 3rd E.P. Gallagher A. Goksoyr M.E. Hahn D.G. Larsson Fish models in toxicology Zebrafish 4 1 2007 9 20
42. M. Celander D.R. Buhler L. Forlin A. Goksoyr C.L. Miranda B.R. Woodin J.J. Stegeman Immunochemical relationships of cytochrome P4503A-like proteins in teleost fish Fish Physiol. Biochem. 15 4 1996 323 332
43. K.M. Chan L.L. Ku P.C. Chan W.K. Cheuk Metallothionein gene expression in zebrafish embryo-larvae and ZFL cell-line exposed to heavy metal ions Mar. Environ. Res. 62 Suppl. 2006 S83 S87
44. W.K. Chan G. Yao Y.-Z. Gu C.A. Bradfield Cross-talk between the aryl hydrocarbon receptor and hypoxia inducible factor signaling pathways. Demonstration of competition and compensation J. Biol. Chem. 274 1999 12115 12123
45. H. Chen J. Hu J. Yang Y. Wang H. Xu Q. Jiang Y. Gong Y. Gu H. Song Generation of a fluorescent transgenic zebrafish for detection of environmental estrogens Aquat. Toxicol. 96 2010 53 61
46. J. Chen S.A. Carney R.E. Peterson W. Heideman Comparative genomics identifies genes mediating cardiotoxicity in the embryonic zebrafish heart Physiol. Genomics 33 2 2008 148 158
47. W.Y. Chen J.A. John C.H. Lin C.Y. Chang Expression pattern of metallothionein, MTF-1 nuclear translocation, and its dna-binding activity in zebrafish (Danio rerio) induced by zinc and cadmium Environ. Toxicol. Chem. 26 1 2007 110 117
48. W.Y. Chen J.A. John C.H. Lin H.F. Lin S.C. Wu C.H. Lin C.Y. Chang Expression of metallothionein gene during embryonic and early larval development in zebrafish Aquat. Toxicol. 69 3 2004 215 227
49. X. Chen L. Li C.K. Wong S.H. Cheng Rapid adaptation of molecular resources from zebrafish and medaka to develop an estuarine/marine model Comp. Biochem. Physiol. C Toxicol. Pharmacol. 149 4 2009 647 655
50. K. Cheshenko F. Brion Y. Le Page N. Hinfray F. Pakdel O. Kah H. Segner R.I. Eggen Expression of zebrafish aromatase CYP19a amd CYP19b genes in response to the ligands of estrogen receptor and aryl hydrocarbon receptor Toxicol. Sci. 96 2 2007 255 267
51. A. Christoffels E.G. Koh J.M. Chia S. Brenner S. Aparicio B. Venkatesh Fugu genome analysis provides evidence for a whole-genome duplication early during the evolution of ray-finned fishes Mol. Biol. Evol. 21 6 2004 1146 1151
52. T.S. Coe P.B. Hamilton A.M. Griffiths D.J. Hodgson M.A. Wahab C.R. Tyler Genetic variation in strains of zebrafish (Danio rerio) and the implications for ecotoxicology studies Ecotoxicology 18 1 2009 144 150
53. M.W. Coughtrie Sulfation through the looking glass – recent advances in sulfotransferase research for the curious Pharmacogenomics J. 2 5 2002 297 308
54. P.M. Craig C. Hogstrand C.M. Wood G.B. McClelland Gene expression endpoints following chronic waterborne copper exposure in a genomic model organism, the zebrafish, Danio rerio Physiol. Genomics 40 1 2009 23 33
55. F.S. de Souza V.F. Bumaschny M.J. Low M. Rubinstein Subfunctionalization of expression and peptide domains following the ancient duplication of the proopiomelanocortin gene in teleost fishes Mol. Biol. Evol. 22 12 2005 2417 2427
56. A.G. De Souza T.J. MacCormack N. Wang L. Li G.G. Goss Large-scale proteome profile of the zebrafish (Danio rerio) gill for physiological and biomarker discovery studies Zebrafish 6 3 2009 229 238
57. M. De Wit D. Keil N. Remmerie K. van der Ven E.J. van den Brandhof D. Knapen E. Witters W. De Coen Molecular targets of TBBPA in zebrafish analysed through integration of genomic and proteomic approaches Chemosphere 74 1 2008 96 105
58. M. Dean T. Annilo Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates Annu. Rev. Genomics. Hum. Genet. 6 2005 123 142
59. P. Dehal J.L. Boore Two rounds of whole genome duplication in the ancestral vertebrate PLoS Biol. 3 10 2005 e314
60. M.S. Denison S.R. Nagy Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals Annu. Rev. Pharmacol. Toxicol. 43 2003 309 334
61. B. Dobbs-McAuliffe Q. Zhao E. Linney Feedback mechanisms regulate retinoic acid production and degradation in the zebrafish embryo Mech. Dev. 121 4 2004 339 350
62. D.C. Dolinoy D. Huang R.L. Jirtle Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development Proc. Natl Acad. Sci. USA 104 32 2007 13056 13061
63. W. Dong H. Teraoka K. Yamazaki S. Tsukiyama S. Imani T. Imagawa J.J. Stegeman R.E. Peterson T. Hiraga 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in the zebrafish embryo: Local circulation failure in the dorsal midbrain is associated with increased apoptosis Toxicol. Sci. 69 1 2002 191 201
64. V. Douard F. Brunet B. Boussau I. Ahrens-Fath V. Vlaeminck-Guillem B. Haendler V. Laudet Y. Guiguen The fate of the duplicated androgen receptor in fishes: A late neofunctionalization event? BMC Evol. Biol. 8 2008 336
65. Y. Doyon J.M. McCammon J.C. Miller F. Faraji C. Ngo G.E. Katibah R. Amora T.D. Hocking L. Zhang E.J. Rebar Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases Nat. Biotechnol. 26 6 2008 702 708
66. N. Dragin Z. Shi R. Madan C.L. Karp M.A. Sartor C. Chen F.J. Gonzalez D.W. Nebert Phenotype of the Cyp1a1/1a2/1b1-/- triple-knockout mouse Mol. Pharmacol. 73 6 2008 1844 1856
67. R.J. Egan C.L. Bergner P.C. Hart J.M. Cachat P.R. Canavello M.F. Elegante S.I. Elkhayat B.K. Bartels A.K. Tien D.H. Tien Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish Behav. Brain Res. 205 1 2009 38 44
68. P.M. Eimon A.L. Rubinstein The use of in vivo zebrafish assays in drug toxicity screening Expert Opin. Drug Metab. Toxicol. 5 4 2009 393 401
69. S. Ekins E.J. Reschly L.R. Hagey M.D. Krasowski Evolution of pharmacologic specificity in the pregnane X receptor BMC Evol. Biol. 8 2008 103
70. S.C. Ekker Zinc finger-based knockout punches for zebrafish genes Zebrafish 5 2 2008 121 123
71. A.A. Elskus E. Monosson A.E. McElroy J.J. Stegeman D.S. Woltering Altered CYP1A expression in Fundulus heteroclitus adults and larvae: A sign of pollutant resistance? Aquat. Toxicol. 45 1999 99 113
72. B.R. Evans S.I. Karchner L.L. Allan R.S. Pollenz R.L. Tanguay M.J. Jenny D.H. Sherr M.E. Hahn Repression of aryl hydrocarbon receptor (AHR) signaling by AHR repressor: Role of DNA binding and competition for AHR nuclear translocator Mol. Pharmacol. 73 2 2008 387 398
73. B.R. Evans S.I. Karchner D.G. Franks M.E. Hahn Duplicate aryl hydrocarbon receptor repressor genes (ahrr1 and ahrr2) in the zebrafish Danio rerio: Structure, function, evolution, and AHR-dependent regulation in vivo Arch. Biochem. Biophys. 441 2 2005 151 167
74. J.E. Fish M.M. Santoro S.U. Morton S. Yu R.F. Yeh J.D. Wythe K.N. Ivey B.G. Bruneau D.Y. Stainier D. Srivastava miR-126 regulates angiogenic signaling and vascular integrity Dev. Cell 15 2 2008 272 284
75. M.C. Fishman Genomics. Zebrafish--the canonical vertebrate Science 294 5545 2001 1290 1291
76. W.M. Fitch Distinguishing homologous from analogous proteins Syst. Zool. 19 1970 99 113
77. J.E. Foley J.R. Yeh M.L. Maeder D. Reyon J.D. Sander R.T. Peterson J.K. Joung Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized pool ENgineering (OPEN) PLoS ONE 4 2 2009 e4348
78. A. Force M. Lynch F.B. Pickett A. Amores Y.-L. Yan J.H. Postlethwait Preservation of duplicate genes by complementary, degenerative mutations Genetics 151 1999 1531 1545
79. M. Froehlicher A. Liedtke K. Groh H. Lopez-Schier S.C. Neuhauss H. Segner R.I. Eggen Estrogen receptor subtype beta2 is involved in neuromast development in zebrafish (Danio rerio) larvae Dev. Biol. 330 1 2009 32 43
80. M. Froehlicher A. Liedtke K.J. Groh S.C. Neuhauss H. Segner R.I. Eggen Zebrafish (Danio rerio) neuromast: Promising biological endpoint linking developmental and toxicological studies Aquat. Toxicol. 95 4 2009 307 319
81. S. Fujita H. Iba Putative promoter regions of miRNA genes involved in evolutionarily conserved regulatory systems among vertebrates Bioinformatics 24 3 2008 303 308
82. N. Garcia-Reyero D.L. Villeneuve K.J. Kroll L. Liu E.F. Orlando K.H. Watanabe M.S. Sepulveda G.T. Ankley N.D. Denslow Expression signatures for a model androgen and antiandrogen in the fathead minnow (Pimephales promelas) ovary Environ. Sci. Technol. 43 7 2009 2614 2619
83. S.G. George B. Taylor Molecular evidence for multiple UDP-glucuronosyltransferase gene familes in fish Mar. Environ. Res. 54 3-5 2002 253 257
84. A.M. Geurts G.J. Cost Y. Freyvert B. Zeitler J.C. Miller V.M. Choi S.S. Jenkins A. Wood X. Cui X. Meng Knockout rats via embryo microinjection of zinc-finger nucleases Science 325 5939 2009 433
85. A.J. Giraldez Y. Mishima J. Rihel R.J. Grocock S. Van Dongen K. Inoue A.J. Enright A.F. Schier Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs Science 312 5770 2006 75 79
86. C.A. Godard J.V. Goldstone M.R. Said R.L. Dickerson B.R. Woodin J.J. Stegeman The new vertebrate CYP1C family: Cloning of new subfamily members and phylogenetic analysis Biochem. Biophys. Res. Commun. 331 4 2005 1016 1024
87. H.M. Goldstone J.J. Stegeman Molecular mechanisms of 2,3,7,8-tetrachlorodibenzo-p-dioxin cardiovascular embryotoxicity Drug Metab. Rev. 38 1-2 2006 261 289
88. J.V. Goldstone Environmental sensing and response genes in cnidaria: The chemical defensome in the sea anemone Nematostella vectensis Cell Biol. Toxicol. 24 6 2008 483 502
89. J.V. Goldstone A. Hamdoun B.J. Cole M. Howard-Ashby D.W. Nebert M. Scally M. Dean D. Epel M.E. Hahn J.J. Stegeman The chemical defensome: Environmental sensing and response genes in the Strongylocentrotus purpuratus genome Dev. Biol. 300 1 2006 366 384
90. J.V. Goldstone M.E. Jonsson L. Behrendt B.R. Woodin M.J. Jenny D.R. Nelson J.J. Stegeman Cytochrome P450 1D1: A novel CYP1A-related gene that is not transcriptionally activated by PCB126 or TCDD Arch. Biochem. Biophys. 482 1-2 2009 7 16
91. M.G. Goll R. Anderson D.Y. Stainier A.C. Spradling M.E. Halpern Transcriptional silencing and reactivation in transgenic zebrafish Genetics 182 3 2009 747 755
92. K. Gradin J. McGuire R.H. Wenger I. Kvietikova M.L. Whitelaw R. Toftgård L. Tora M. Gassmann L. Poellinger Functional interference between hypoxia and dioxin signal transduction pathways: Competition for recruitment of the Arnt transcription factor Mol. Cell. Biol. 16 10 1996 5221 5231
93. X. Gu S. Ke D. Liu T. Sheng Y. Tian Cross-talk between aryl hydrocarbon receptor and pregnane-X-receptor pathways Toxicol. Sci. (The Toxicologist Supplement) 96 Suppl. 2007 294 (Abstract #1420)
94. S. Guo Using zebrafish to assess the impact of drugs on neural development and function Expert Opin. Drug Discov. 4 7 2009 715 726
95. N. Gurvich M.G. Berman B.S. Wittner R.C. Gentleman P.S. Klein J.B. Green Association of valproate-induced teratogenesis with histone deacetylase inhibition in vivo FASEB J. 19 9 2005 1166 1168
96. V. Guryev M.J. Koudijs E. Berezikov S.L. Johnson R.H. Plasterk F.J. van Eeden E. Cuppen Genetic variation in the zebrafish Genome Res. 16 4 2006 491 497
97. M.E. Hahn Aryl hydrocarbon receptors: Diversity and evolution Chem. Biol. Interact. 141 1/2 2002 131 160
98. M.E. Hahn E.V. Hestermann Chapter 5. Receptor-mediated Mechanisms of Toxicity R.T. Di Giulio D.E. Hinton The Toxicology of Fishes 2007 Taylor & Francis 235 272
99. M.E. Hahn S.I. Karchner B.R. Evans D.G. Franks R.R. Merson J.M. Lapseritis Unexpected diversity of aryl hydrocarbon receptors in non-mammalian vertebrates: Insights from comparative genomics J. Exp. Zool. A Comp. Exp. Biol. 305 9 2006 693 706
100. M.E. Hahn S.I. Karchner D.G. Franks B.R. Woodin K.L. Barott M.J. Cipriano A.G. McArthur The transcriptional response to oxidative stress in zebrafish embryos Toxicol. Sci. (The Toxicologist Supplement) 96 2007 326 327 (Abstract #1578)
101. Hahn, M. E., Merson R. R., and Karchner S. I. (2005). Xenobiotic receptors in fishes: Structural and functional diversity and evolutionary insights. In Biochemistry and Molecular Biology of Fishes , Vol. 6 – Environmental Toxicology (T. W. Moon and T. P. Mommsen, eds.), pp. 191–228.
102. H.M. Handley-Goldstone M.W. Grow J.J. Stegeman Cardiovascular gene expression profiles of dioxin exposure in zebrafish embryos Toxicol. Sci. 85 1 2005 683 693
103. E.A. Hassoun A.C. Walter N.Z. Alsharif S.J. Stohs Modulation of TCDD-induced fetotoxicity and oxidative stress in embryonic and placental tissues of C57BL/6J mice by vitamin E succinate and ellagic acid Toxicology 124 1 1997 27 37
104. Y. Haudry H. Berube I. Letunic P.D. Weeber J. Gagneur C. Girardot M. Kapushesky D. Arendt P. Bork A. Brazma 4DXpress: A database for cross-species expression pattern comparisons Nucleic Acids Res. 36 Database issue 2008 D847 853
105. M.B. Hawkins J. Godwin D. Crews P. Thomas The distributions of the duplicate oestrogen receptors ER-beta a and ER-beta b in the forebrain of the Atlantic croaker (Micropogonias undulatus): Evidence for subfunctionalization after gene duplication Proc. R. Soc. B 272 1563 2005 633 641
106. X. He Q. Ma Induction of metallothionein I by arsenic via metal-activated transcription factor 1: Critical role of C-terminal cysteine residues in arsenic sensing J. Biol. Chem. 284 19 2009 12609 12621
107. Z. Hegedus A. Zakrzewska V.C. Agoston A. Ordas P. Racz M. Mink H.P. Spaink A.H. Meijer Deep sequencing of the zebrafish transcriptome response to mycobacterium infection Mol. Immunol. 46 15 2009 2918 2930
108. W. Heideman D.S. Antkiewicz S.A. Carney R.E. Peterson Zebrafish and cardiac toxicology Cardiovasc. Toxicol. 5 2 2005 203 214
109. T.C. Heiden C.A. Struble M.L. Rise M.J. Hessner R.J. Hutz M.J. Carvan 3rd Molecular targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) within the zebrafish ovary: Insights into TCDD-induced endocrine disruption and reproductive toxicity Reprod. Toxicol. 25 1 2008 47 57
110. J.J. Heindel Animal models for probing the developmental basis of disease and dysfunction paradigm Basic Clin. Pharmacol. Toxicol. 102 2 2008 76 81
111. T.B. Henry J.T. McPherson E.D. Rogers T.P. Heah S.A. Hawkins A.C. Layton G.S. Sayler Changes in the relative expression pattern of multiple vitellogenin genes in adult male and larval zebrafish exposed to exogenous estrogens Comp. Biochem. Physiol. A Mol. Integr. Physiol. 154 1 2009 119 126
112. T.B. Henry F.M. Menn J.T. Fleming J. Wilgus R.N. Compton G.S. Sayler Attributing effects of aqueous C60 nano-aggregates to tetrahydrofuran decomposition products in larval zebrafish by assessment of gene expression Environ. Health Perspect. 115 7 2007 1059 1065
113. R.E. Hernandez A.P. Putzke J.P. Myers L. Margaretha C.B. Moens Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development Development 134 1 2007 177 187
114. A. Hill C.V. Howard U. Strahle A. Cossins Neurodevelopmental defects in zebrafish (Danio rerio) at environmentally relevant dioxin (TCDD) concentrations Toxicol. Sci. 76 2 2003 392 399
115. D.E. Hinton S.W. Kullman R.C. Hardman D.C. Volz P.J. Chen M. Carney D.C. Bencic Resolving mechanisms of toxicity while pursuing ecotoxicological relevance? Mar. Pollut. Bull. 51 8-12 2005 635 648
116. O. Hobert Gene regulation by transcription factors and microRNAs Science 319 5871 2008 1785 1786
117. J.L. Hoffmann J.T. Oris Altered gene expression: A mechanism for reproductive toxicity in zebrafish exposed to benzo[a]pyrene Aquat. Toxicol. 78 4 2006 332 340
118. J.L. Hoffmann R.G. Thomason D.M. Lee J.L. Brill B.B. Price G.J. Carr D.J. Versteeg Hepatic gene expression profiling using GeneChips in zebrafish exposed to 17alpha-methyldihydrotestosterone Aquat. Toxicol. 87 2 2008 69 80
119. J.L. Hoffmann S.P. Torontali R.G. Thomason D.M. Lee J.L. Brill B.B. Price G.J. Carr D.J. Versteeg Hepatic gene expression profiling using Genechips in zebrafish exposed to 17alpha-ethynylestradiol Aquat. Toxicol. 79 3 2006 233 246
120. C. Hogstrand D. Zheng G. Feeney P. Cunningham P. Kille Zinc-controlled gene expression by metal-regulatory transcription factor 1 (MTF1) in a model vertebrate, the zebrafish Biochem. Soc. Trans. 36 Pt 6 2008 1252 1257
121. T.F. Holth R. Nourizadeh-Lillabadi M. Blaesbjerg M. Grung H. Holbech G.I. Petersen P. Alestrom K. Hylland Differential gene expression and biomarkers in zebrafish (Danio rerio) following exposure to produced water components Aquat. Toxicol. 90 4 2008 277 291
122. W. Hu L. Cheng H. Xia D. Sun D. Li P. Li Y. Song X. Ma Teratogenic effects of sodium thiosulfate on developing zebrafish embryos Front. Biosci. 14 2009 3680 3687
123. H. Huang Q. Wu Cloning and comparative analyses of the zebrafish Ugt repertoire reveal its evolutionary diversity PLoS ONE 5 2 2004 e9144
124. A. Hudder R.F. Novak miRNAs: Effectors of environmental influences on gene expression and disease Toxicol. Sci. 103 2 2008 228 240
125. J.P. Incardona M.G. Carls H. Teraoka C.A. Sloan T.K. Collier N.L. Scholz Aryl hydrocarbon receptor-independent toxicity of weathered crude oil during fish development Environ. Health Perspect. 113 12 2005 1755 1762
126. J.P. Incardona H.L. Day T.K. Collier N.L. Scholz Developmental toxicity of 4-ring polycyclic aromatic hydrocarbons in zebrafish is differentially dependent on AH receptor isoforms and hepatic cytochrome P4501A metabolism Toxicol. Appl. Pharmacol. 217 3 2006 308 321
127. M.J. Jenny M.E. Hahn MicroRNAs in developmental toxicology: Effects of TCDD on MicroRNA expression in embryos Toxicological Sciences (The Toxicologist Supplement) 108 1 2009 20 (Abstract #104)
128. M.J. Jenny S.I. Karchner D.G. Franks B.R. Woodin J.J. Stegeman M.E. Hahn Distinct roles of two zebrafish AHR repressors (AHRRa and AHRRb) in embryonic development and regulating the response to 2,3,7,8-tetrachlorodibenzo-p-dioxin Toxicol. Sci. 110 2 2009 426 441
129. Y. Jin R. Chen L. Sun H. Qian W. Liu Z. Fu Induction of estrogen-responsive gene transcription in the embryo, larval, juvenile and adult life stages of zebrafish as biomarkers of short-term exposure to endocrine disrupting chemicals Comp. Biochem. Physiol. C Toxicol. Pharmacol. 150 3 2009 414 420
130. Y. Jin T.M. Penning Aldo-keto reductases and bioactivation/detoxication Annu. Rev. Pharmacol. Toxicol. 47 2007 263 292
131. R.L. Jirtle M.K. Skinner Environmental epigenomics and disease susceptibility Nat. Rev. Genet. 8 4 2007 253 262
132. R.W. Jones M.N. Huffman Fish embryos as bio-assay material in testing chemicals for effects on cell division and differentiation Trans. Am. Microsc. Soc. 76 1957 177 183
133. M.E. Jonsson B. Brunstrom I. Brandt The zebrafish gill model: Induction of CYP1A, EROD and PAH adduct formation Aquat. Toxicol. 91 1 2009 62 70
134. M.E. Jonsson D.G. Franks B.R. Woodin M.J. Jenny R.A. Garrick L. Behrendt M.E. Hahn J.J. Stegeman The tryptophan photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) binds multiple AHRs and induces multiple CYP1 genes via AHR2 in zebrafish Chem. Biol. Interact. 181 3 2009 447 454
135. M.E. Jonsson M.J. Jenny B.R. Woodin M.E. Hahn J.J. Stegeman Role of AHR2 in the expression of novel cytochrome P450 1 family genes, cell cycle genes, and morphological defects in developing zebra fish exposed to 3,3′,4,4′,5-pentachlorobiphenyl or 2,3,7,8-tetrachlorodibenzo-p-dioxin Toxicol. Sci. 100 1 2007 180 193
136. D. Jupiter H. Chen V. VanBuren STARNET 2: A web-based tool for accelerating discovery of gene regulatory networks using microarray co-expression data BMC Bioinformatics 10 2009 332
137. S.I. Karchner D.G. Franks M.E. Hahn AHR1B, a new functional aryl hydrocarbon receptor in zebrafish: Tandem arrangement of ahr1b and ahr2 genes Biochem. J. 392 Pt 1 2005 153 161
138. C.K. Kaufman R.M. White L. Zon Chemical genetic screening in the zebrafish embryo Nat. Protoc. 4 10 2009 1422 1432
139. U. Kausch M. Alberti S. Haindl J. Budczies B. Hock Biomarkers for exposure to estrogenic compounds: Gene expression analysis in zebrafish (Danio rerio) Environ. Toxicol. 23 1 2008 15 24
140. T.W. Kensler N. Wakabayashi Nrf2: Friend or Foe for Chemoprevention? Carcinogenesis 31 1 2010 90 99
141. L.J. Kily Y.C. Cowe O. Hussain S. Patel S. McElwaine F.E. Cotter C.H. Brennan Gene expression changes in a zebrafish model of drug dependency suggest conservation of neuro-adaptation pathways J. Exp. Biol. 211 Pt 10 2008 1623 1634
142. T.C. King Heiden J. Spitsbergen W. Heideman R.E. Peterson Persistent adverse effects on health and reproduction caused by exposure of zebrafish to 2,3,7,8-tetrachlorodibenzo-p-dioxin during early development and gonad differentiation Toxicol. Sci. 109 1 2009 75 87
143. M. Kishida G.V. Callard Distinct cytochrome P450 aromatase isoforms in zebrafish (Danio rerio) brain and ovary are differentially programmed and estrogen regulated during early development Endocrinology 142 2 2001 740 750
144. S.S. Kitambi K.J. McCulloch R.T. Peterson J.J. Malicki Small molecule screen for compounds that affect vascular development in the zebrafish retina Mech. Dev. 126 5-6 2009 464 477
145. H.E. Kleiner S.V. Vulimiri W.B. Hatten M.J. Reed D.W. Nebert C.R. Jefcoate J. DiGiovanni Role of cytochrome p4501 family members in the metabolic activation of polycyclic aromatic hydrocarbons in mouse epidermis Chem. Res. Toxicol. 17 12 2004 1667 1674
146. P. Kling L. Forlin Proteomic studies in zebrafish liver cells exposed to the brominated flame retardants HBCD and TBBPA Ecotoxicol. Environ. Saf. 72 7 2009 1985 1993
147. P. Kling A. Norman P.L. Andersson L. Norrgren L. Forlin Gender-specific proteomic responses in zebrafish liver following exposure to a selected mixture of brominated flame retardants Ecotoxicol. Environ. Saf. 71 2 2008 319 327
148. M. Kobayashi K. Itoh T. Suzuki H. Osanai K. Nishikawa Y. Katoh Y. Takagi M. Yamamoto Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system Genes Cells 7 8 2002 807 820
149. M. Kobayashi L. Li N. Iwamoto Y. Nakajima-Takagi H. Kaneko Y. Nakayama M. Eguchi Y. Wada Y. Kumagai M. Yamamoto The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds Mol. Cell. Biol. 29 2 2009 493 502
150. J.A. Koch D.J. Waxman P450 phosphorylation in isolated hepatocytes and in vivo Methods Enzymol. 206 1991 305 315
151. C. Kohle K.W. Bock Coordinate regulation of Phase I and II xenobiotic metabolisms by the Ah receptor and Nrf2 Biochem. Pharmacol. 73 12 2007 1853 1862
152. C. Kohle K.W. Bock Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor Biochem. Pharmacol. 77 4 2009 689 699
153. D. Kokel R.T. Peterson Chemobehavioural phenomics and behaviour-based psychiatric drug discovery in the zebrafish Brief Funct. Genomics Proteomics 7 6 2008 483 490
154. M.D. Krasowski K. Yasuda L.R. Hagey E.G. Schuetz Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors) Nucl. Recept. 3 2005 2
155. J.A. Kreiling R. Creton C. Reinisch Early embryonic exposure to polychlorinated biphenyls disrupts heat-shock protein 70 cognate expression in zebrafish J. Toxicol. Environ. Health A. 70 12 2007 1005 1013
156. P.H. Krone T.G. Evans S.R. Blechinger Heat shock gene expression and function during zebrafish embryogenesis Semin. Cell Dev. Biol. 14 5 2003 267 274
157. S.K. Krueger D.E. Williams Mammalian flavin-containing monooxygenases: Structure/function, genetic polymorphisms and role in drug metabolism Pharmacol. Ther. 106 3 2005 357 387
158. B.W. Kusik M.J. Carvan 3rd A.J. Udvadia Detection of mercury in aquatic environments using EPRE reporter zebrafish Mar. Biotechnol. (NY) 10 6 2008 750 757
159. S.H. Lam S. Mathavan Y. Tong H. Li R.K. Karuturi Y. Wu V.B. Vega E.T. Liu Z. Gong Zebrafish whole-adult-organism chemogenomics for large-scale predictive and discovery chemical biology PLoS Genet. 4 7 2008 e1000121
160. S.H. Lam C.L. Winata Y. Tong S. Korzh W.S. Lim V. Korzh J. Spitsbergen S. Mathavan L.D. Miller E.T. Liu Transcriptome kinetics of arsenic-induced adaptive response in zebrafish liver Physiol. Genomics 27 3 2006 351 361
161. E. Lammer G.J. Carr K. Wendler J.M. Rawlings S.E. Belanger T. Braunbeck Is the fish embryo toxicity test (FET) with the zebrafish (Danio rerio) a potential alternative for the fish acute toxicity test? Comp. Biochem. Physiol. C Toxicol. Pharmacol. 149 2 2009 196 209
162. E. Lammer H.G. Kamp V. Hisgen M. Koch D. Reinhard E.R. Salinas K. Wendler S. Zok T. Braunbeck Development of a flow-through system for the fish embryo toxicity test (FET) with the zebrafish (Danio rerio) Toxicol In Vitro 23 7 2009 1436 1442
163. N. Lassen T. Estey R.L. Tanguay A. Pappa M.J. Reimers V. Vasiliou Molecular cloning, baculovirus expression, and tissue distribution of the zebrafish aldehyde dehydrogenase 2 Drug Metab. Dispos. 33 5 2005 649 656
164. C. Latchoumycandane P.P. Mathur Effects of vitamin E on reactive oxygen species-mediated 2,3,7,8-tetrachlorodi-benzo-p-dioxin toxicity in rat testis J. Appl. Toxicol. 22 5 2002 345 351
165. Y. Le Page M. Scholze O. Kah F. Pakdel Assessment of xenoestrogens using three distinct estrogen receptors and the zebrafish brain aromatase gene in a highly responsive glial cell system Environ. Health Perspect. 114 5 2006 752 758
166. M.J. Leaver J. Wright P. Hodgson E. Boukouvala S.G. George Piscine UDP-glucuronosyltransferase 1B Aquat. Toxicol. 84 3 2007 356 365
167. K. Lee L.D. Burgoon L. Lamb E. Dere T.R. Zacharewski J.B. Hogenesch J.J. LaPres Identification and characterization of genes susceptible to transcriptional cross-talk between the hypoxia and dioxin signaling cascades Chem. Res. Toxicol. 19 10 2006 1284 1293
168. M.O. Lee C.L. Manthey N.E. Sladek Identification of mouse liver aldehyde dehydrogenases that catalyze the oxidation of retinaldehyde to retinoic acid Biochem. Pharmacol. 42 6 1991 1279 1285
169. K.A. Lefebvre S.C. Tilton T.K. Bammler R.P. Beyer S. Srinouanprachan P.L. Stapleton F.M. Farin E.P. Gallagher Gene expression profiles in zebrafish brain after acute exposure to domoic acid at symptomatic and asymptomatic doses Toxicol. Sci. 107 1 2009 65 77
170. D. Li C. Lu J. Wang W. Hu Z. Cao D. Sun H. Xia X. Ma Developmental mechanisms of arsenite toxicity in zebrafish (Danio rerio) embryos Aquat. Toxicol. 91 3 2009 229 237
171. L. Li M. Kobayashi H. Kaneko Y. Nakajima-Takagi Y. Nakayama M. Yamamoto Molecular Evolution of Keap1: Two Keap1 molecules with distinctive intervening region structures are conserved among fish J. Biol. Chem. 283 6 2008 3248 3255
172. Y. Lin Y. Chen X. Yang D. Xu S. Liang Proteome analysis of a single zebrafish embryo using three different digestion strategies coupled with liquid chromatography-tandem mass spectrometry Anal. Biochem. 394 2 2009 177 185
173. M.Y. Liu Y.S. Yang T. Sugahara S. Yasuda M.C. Liu Identification of a novel zebrafish SULT1 cytosolic sulfotransferase: Cloning, expression, characterization, and developmental expression study Arch. Biochem. Biophys. 437 1 2005 10 19
174. M. Lynch J.S. Conery The evolutionary fate and consequences of duplicate genes Science 290 5494 2000 1151 1155
175. Q. Ma Xenobiotic-activated receptors: From transcription to drug metabolism to disease Chem. Res. Toxicol. 21 9 2008 1651 1671
176. A.B. MacKay A.A. Mhanni R.A. McGowan P.H. Krone Immunological detection of changes in genomic DNA methylation during early zebrafish development Genome 50 8 2007 778 785
177. P.I. Mackenzie K.W. Bock B. Burchell C. Guillemette S. Ikushiro T. Iyanagi J.O. Miners I.S. Owens D.W. Nebert Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily Pharmacogenet. Genomics 15 10 2005 677 685
178. P.I. Mackenzie A. Rogers J. Treloar B.R. Jorgensen J.O. Miners R. Meech Identification of UDP glycosyltransferase 3A1 as a UDP N-acetylglucosaminyltransferase J. Biol. Chem. 283 52 2008 36205 36210
179. D. Macleod V.H. Clark A. Bird Absence of genome-wide changes in DNA methylation during development of the zebrafish Nat. Genet. 23 2 1999 139 140
180. J.M. Maglich C.M. Stoltz B. Goodwin D. Hawkins-Brown J.T. Moore S.A. Kliewer Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification Mol. Pharmacol. 62 3 2002 638 646
181. M. Margulies M. Egholm W.E. Altman S. Attiya J.S. Bader L.A. Bemben J. Berka M.S. Braverman Y.J. Chen Z. Chen Genome sequencing in microfabricated high-density picolitre reactors Nature 437 7057 2005 376 380
182. C.C. Martin L. Laforest M.A. Akimenko M. Ekker A role for DNA methylation in gastrulation and somite patterning Dev. Biol. 206 2 1999 189 205
183. C.J. Martyniuk E.R. Gerrie J.T. Popesku M. Ekker V.L. Trudeau Microarray analysis in the zebrafish (Danio rerio) liver and telencephalon after exposure to low concentration of 17alpha-ethinylestradiol Aquat. Toxicol. 84 1 2007 38 49
184. L.K. Mathew E.A. Andreasen R.L. Tanguay Aryl hydrocarbon receptor activation inhibits regenerative growth Mol. Pharmacol. 69 1 2006 257 265
185. L.K. Mathew S.S. Sengupta J. Ladu E.A. Andreasen R.L. Tanguay Crosstalk between AHR and Wnt signaling through R-Spondin1 impairs tissue regeneration in zebrafish FASEB J. 22 8 2008 3087 3096
186. L.K. Mathew M.T. Simonich R.L. Tanguay AHR-dependent misregulation of Wnt signaling disrupts tissue regeneration Biochem. Pharmacol. 77 4 2009 498 507
187. C.J. Mattingly T.H. Hampton K.M. Brothers N.E. Griffin A. Planchart Perturbation of defense pathways by low-dose arsenic exposure in zebrafish embryos Environ. Health Perspect. 117 6 2009 981 987
188. C.J. Mattingly J.A. McLachlan W.A. Toscano Jr. Green fluorescent protein (GFP) as a marker of aryl hydrocarbon receptor (AhR) function in developing zebrafish (Danio rerio) Environ. Health Perspect. 109 8 2001 845 849
189. A.G. McArthur T. Hegelund R.L. Cox J.J. Stegeman M. Liljenberg U. Olsson P. Sundberg M.C. Celander Phylogenetic analysis of the cytochrome P450 3 (CYP3) gene family J. Mol. Evol. 57 2 2003 200 211
190. F. Meier-Abt Y. Mokrab K. Mizuguchi Organic anion transporting polypeptides of the OATP/SLCO superfamily: Identification of new members in nonmammalian species, comparative modeling and a potential transport mode J. Membr. Biol. 208 3 2005 213 227
191. X. Meng M.B. Noyes L.J. Zhu N.D. Lawson S.A. Wolfe Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases Nat. Biotechnol. 26 6 2008 695 701
192. A. Menuet E. Pellegrini I. Anglade O. Blaise V. Laudet O. Kah F. Pakdel Molecular characterization of three estrogen receptor forms in zebrafish: Binding characteristics, transactivation properties, and tissue distributions Biol. Reprod. 66 6 2002 1881 1892
193. A.A. Mhanni R.A. McGowan Global changes in genomic methylation levels during early development of the zebrafish embryo Dev. Genes. Evol. 214 8 2004 412 417
194. W. Miao L. Hu P.J. Scrivens G. Batist Transcriptional regulation of NF-E2 p45-related factor (NRF2) expression by the aryl hydrocarbon receptor-xenobiotic response element signaling pathway: Direct cross-talk between phase I and II drug-metabolizing enzymes J. Biol. Chem. 280 21 2005 20340 20348
195. D.J. Milan C.A. Macrae Zebrafish genetic models for arrhythmia Prog. Biophys. Mol. Biol. 98 2-3 2008 301 308
196. R. Mindnich J. Adamski Zebrafish 17beta-hydroxysteroid dehydrogenases: An evolutionary perspective Mol. Cell Endocrinol. 301 1-2 2009 20 26
197. C.L. Miranda W.G. Chung J.L. Wang-Buhler T. Musafia-Jeknic W.M. Baird D.R. Buhler Comparative in vitro metabolism of benzo[a]pyrene by recombinant zebrafish CYP1A and liver microsomes from beta-naphthoflavone-treated rainbow trout Aquat. Toxicol. 80 2 2006 101 108
198. I.D. Moffat P.C. Boutros T. Celius J. Linden R. Pohjanvirta A.B. Okey microRNAs in adult rodent liver are refractory to dioxin treatment Toxicol. Sci. 99 2 2007 470 487
199. L.B. Moore J.M. Maglich D.D. McKee B. Wisely T.M. Willson S.A. Kliewer M.H. Lambert J.T. Moore Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors Mol. Endocrinol. 16 5 2002 977 986
200. H.G. Morrison M.F. Oleksiak N.W. Cornell M.L. Sogin J.J. Stegeman Identification of cytochrome P-450 1A (CYP1A) genes from two teleost fish, toadfish (Opsanus tau) and scup (Stenotomus chrysops), and phylogenetic analysis of CYP1A genes Biochem. J. 308 1995 97 104
201. H.G. Morrison E.J. Weil S.I. Karchner M.L. Sogin J.J. Stegeman Molecular cloning of CYP1A from the estuarine fish Fundulus heteroclitus and phylogenetic analysis of CYP1 genes: Update with new sequences Comp. Biochem. Physiol. C. Pharmacol. Toxicol. Endocrinol. 121 1-3 1998 s231 s240
202. S.U. Morton P.J. Scherz K.R. Cordes K.N. Ivey D.Y. Stainier D. Srivastava microRNA-138 modulates cardiac patterning during embryonic development Proc. Natl Acad. Sci. USA 105 46 2008 17830 17835
203. R. Nagel DarT: The embryo test with the Zebrafish Danio rerio -- a general model in ecotoxicology and toxicology Altex 19 Suppl. 1 2002 38 48
204. A. Nasevicius S.C. Ekker Effective targeted gene ‘knockdown’ in zebrafish Nat. Genet. 26 2 2000 216 220
205. NCI (1984). Use of small fish in carcinogenicity testing. Proceedings of a symposium. Bethesda, Maryland, December 8–10, 1981. Natl Cancer Inst. Monogr. 65 : 1–409.
206. D.W. Nebert T.P. Dalton The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis Nat. Rev. Cancer 6 12 2006 947 960
207. C.J. Neumann C. Nuesslein-Volhard Patterning of the zebrafish retina by a wave of sonic hedgehog activity Science 289 5487 2000 2137 2139
208. T. Nguyen P. Nioi C.B. Pickett The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress J. Biol. Chem. 284 20 2009 13291 13295
209. R. Nourizadeh-Lillabadi J.L. Lyche C. Almaas B. Stavik S.J. Moe M. Aleksandersen V. Berg K.S. Jakobsen N.C. Stenseth J.U. Skare Transcriptional regulation in liver and testis associated with developmental and reproductive effects in male zebrafish exposed to natural mixtures of persistent organic pollutants (POP) J. Toxicol. Environ. Health A. 72 3-4 2009 112 130
210. NRC Scientific Frontiers in Developmental Toxicology and Risk Assessment 2000 National Academy Press Washington, DC
211. B. Oesch-Bartlomowicz F. Oesch Role of cAMP in mediating AHR signaling Biochem. Pharmacol. 77 4 2009 627 641
212. F. Ohtake Y. Fujii-Kuriyama S. Kato AhR acts as an E3 ubiquitin ligase to modulate steroid receptor functions Biochem. Pharmacol. 77 4 2009 474 484
213. A.B. Okey An aryl hydrocarbon receptor odyssey to the shores of toxicology: The Deichmann lecture, international congress of toxicology-XI Toxicol. Sci. 98 1 2007 5 38
214. M.F. Oleksiak S. Wu C. Parker W. Qu R. Cox D.C. Zeldin J.J. Stegeman Identification and regulation of a new vertebrate cytochrome P450 subfamily, the CYP2Ps, and functional characterization of CYP2P3, a conserved arachidonic acid epoxygenase/19-hydroxylase Arch. Biochem. Biophys. 411 2 2003 223 234
215. D.P. Pandey D. Picard miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA Mol. Cell. Biol. 29 13 2009 3783 3790
216. A. Pandini M.S. Denison Y. Song A.A. Soshilov L. Bonati Structural and functional characterization of the aryl hydrocarbon receptor ligand binding domain by homology modeling and mutational analysis Biochemistry 46 3 2007 696 708
217. A. Pandini A.A. Soshilov Y. Song J. Zhao L. Bonati M.S. Denison Detection of the TCDD binding-fingerprint within the Ah receptor ligand binding domain by structurally driven mutagenesis and functional analysis Biochemistry 48 25 2009 5972 5983
218. Y. Pang J. Dong P. Thomas Estrogen signaling characteristics of Atlantic croaker G protein-coupled receptor 30 (GPR30) and evidence it is involved in maintenance of oocyte meiotic arrest Endocrinology 149 7 2008 3410 3426
219. Y. Pang P. Thomas Involvement of estradiol-17beta and its membrane receptor, G protein coupled receptor 30 (GPR30) in regulation of oocyte maturation in zebrafish, Danio rario Gen. Comp. Endocrinol. 161 1 2009 58 61
220. C. Parng In vivo zebrafish assays for toxicity testing Curr. Opin. Drug Discov. Devel. 8 1 2005 100 106
221. W.R. Pearson Phylogenies of glutathione transferase families Methods Enzymol. 401 2005 186 204
222. T.M. Penning J.E. Drury Human aldo-keto reductases: Function, gene regulation, and single nucleotide polymorphisms Arch. Biochem. Biophys. 464 2 2007 241 250
223. R.T. Peterson Chemical biology and the limits of reductionism Nat. Chem. Biol. 4 11 2008 635 638
224. S. Pittlik S. Domingues A. Meyer G. Begemann Expression of zebrafish aldh1a3 (raldh3) and absence of aldh1a1 in teleosts Gene Expr. Patterns 8 3 2008 141 147
225. R.H. Plasterk Micro RNAs in animal development Cell 124 5 2006 877 881
226. F. Pomati C.J. Cotsapas S. Castiglioni E. Zuccato D. Calamari Gene expression profiles in zebrafish (Danio rerio) liver cells exposed to a mixture of pharmaceuticals at environmentally relevant concentrations Chemosphere 70 1 2007 65 73
227. S.R. Pondugula H. Dong T. Chen Phosphorylation and protein-protein interactions in PXR-mediated CYP3A repression Expert Opin. Drug Metab. Toxicol. 5 8 2009 861 873
228. M. Popovic R. Zaja J. Loncar T. Smital A novel ABC transporter: The first insight into zebrafish (Danio rerio) Abch1 Mar. Environ. Res. 2009 PMID 19926124.
229. J. Postlethwait A. Amores W. Cresko A. Singer Y.L. Yan Subfunction partitioning, the teleost radiation and the annotation of the human genome Trends Genet. 20 10 2004 481 490
230. J.H. Postlethwait The zebrafish genome: A Review and msx Gene Case Study Vertebrate Genomes Vol. 2 2006 Karger Basel pp. 183–197.
231. J.H. Postlethwait The zebrafish genome in context: Ohnologs gone missing J. Exp. Zool. B Mol. Dev. Evol. 308 5 2006 563 577
232. J.C. Prasad J.V. Goldstone C.J. Camacho S. Vajda J.J. Stegeman Ensemble modeling of substrate binding to cytochromes P450: Analysis of catalytic differences between CYP1A orthologs Biochemistry 46 10 2007 2640 2654
233. A.L. Prasch E.A. Andreasen R.E. Peterson W. Heideman Interactions between 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and hypoxia signaling pathways in zebrafish: Hypoxia decreases responses to TCDD in zebrafish embryos Toxicol. Sci. 78 1 2004 68 77
234. A.L. Prasch R.L. Tanguay V. Mehta W. Heideman R.E. Peterson Identification of zebrafish ARNT1 homologs: 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in the developing zebrafish requires ARNT1 Mol. Pharmacol. 69 3 2006 776 787
235. A.L. Prasch H. Teraoka S.A. Carney W. Dong T. Hiraga J.J. Stegeman W. Heideman R.E. Peterson Aryl hydrocarbon receptor 2 mediates 2,3,7,8-tetrachlorodibenzo-p-dioxin developmental toxicity in zebrafish Toxicol. Sci. 76 2003 138 150
236. A. Puga C. Ma J.L. Marlowe The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways Biochem. Pharmacol. 77 4 2009 713 722
237. H. Qiu S. Taudien H. Herlyn J. Schmitz Y. Zhou G. Chen R. Roberto M. Rocchi M. Platzer L. Wojnowski CYP3 phylogenomics: Evidence for positive selection of CYP3A4 and CYP3A7 Pharmacogenet. Genomics 18 1 2008 53 66
238. X. Qu R. Swanson R. Day J. Tsai A guide to template based structure prediction Curr. Protein Pept. Sci. 10 3 2009 270 285
239. K. Rai I.J. Huggins S.R. James A.R. Karpf D.A. Jones B.R. Cairns DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45 Cell 135 7 2008 1201 1212
240. D. Raldua P.J. Babin Simple, rapid zebrafish larva bioassay for assessing the potential of chemical pollutants and drugs to disrupt thyroid gland function Environ. Sci. Technol. 43 17 2009 6844 6850
241. C.M. Reddy A cautionary tale about evaluating analytical methods to assess contamination after oil spills Mar. Pollut. Bull. 56 7 2008 1380
242. G. Redlich U.M. Zanger S. Riedmaier N. Bache A.B. Giessing M. Eisenacher C. Stephan H.E. Meyer O.N. Jensen K. Marcus Distinction between human cytochrome P450 (CYP) isoforms and identification of new phosphorylation sites by mass spectrometry J. Proteome. Res. 7 11 2008 4678 4688
243. M.J. Reimers M.E. Hahn R.L. Tanguay Two zebrafish alcohol dehydrogenases share common ancestry with mammalian class I, II, IV, and V ADH genes but have distinct functional characteristics J. Biol. Chem. 279 2004 38303 38312
244. M.J. Reimers M.E. Hahn R.L. Tanguay Two zebrafish alcohol dehydrogenases share common ancestry with mammalian class I, II, IV, and V alcohol dehydrogenase genes but have distinct functional characteristics J. Biol. Chem. 279 37 2004 38303 38312
245. E.J. Reschly A.C. Bainy J.J. Mattos L.R. Hagey N. Bahary S.R. Mada J. Ou R. Venkataramanan M.D. Krasowski Functional evolution of the vitamin D and pregnane X receptors BMC Evol. Biol. 7 2007 222
246. B. Ruggeri M. Ubaldi A. Lourdusamy L. Soverchia R. Ciccocioppo G. Hardiman M.E. Baker F. Palermo A.M. Polzonetti-Magni Variation of the genetic expression pattern after exposure to estradiol-17beta and 4-nonylphenol in male zebrafish (Danio rerio) Gen. Comp. Endocrinol. 158 1 2008 138 144
247. N.A. Sabaliauskas C.A. Foutz J.R. Mest L.R. Budgeon A.T. Sidor J.A. Gershenson S.B. Joshi K.C. Cheng High-throughput zebrafish histology Methods 39 3 2006 246 254
248. S. Safe M. Wormke Inhibitory aryl hydrocarbon receptor-estrogen receptor-α cross-talk and mechanisms of action Chem. Res. Toxicol. 16 7 2003 807 816
249. E.M. Santos V.L. Workman G.C. Paull A.L. Filby K.J. Van Look P. Kille C.R. Tyler Molecular basis of sex and reproductive status in breeding zebrafish Physiol. Genomics. 30 2 2007 111 122
250. J.J. Schlezinger J. Keller L.A. Verbrugge J.J. Stegeman 3,3′,4,4′-Tetrachlorobiphenyl oxidation in fish, bird and reptile species: Relationship to cytochrome P450 1A inactivation and reactive oxygen production Comp. Biochem. Physiol. C Toxicol. Pharmacol. 125 3 2000 273 286
251. J.J. Schlezinger W.D. Struntz J.V. Goldstone J.J. Stegeman Uncoupling of cytochrome P450 1A and stimulation of reactive oxygen species production by co-planar polychlorinated biphenyl congeners Aquat. Toxicol. 77 4 2006 422 432
252. J.J. Schlezinger R.D. White J.J. Stegeman Oxidative inactivation of cytochrome P450 1A (CYP1A) stimulated by 3,3′,4,4′-tetrachlorobiphenyl: Production of reactive oxygen by vertebrate CYP1As Mol. Pharmacol. 56 1999 588 597
253. R.H. Schreurs E. Sonneveld J.H. Jansen W. Seinen B. van der Burg Interaction of polycyclic musks and UV filters with the estrogen receptor (ER), androgen receptor (AR), and progesterone receptor (PR) in reporter gene bioassays Toxicol. Sci. 83 2 2005 264 272
254. H. Segner Zebrafish (Danio rerio) as a model organism for investigating endocrine disruption Comp. Biochem. Physiol. C Toxicol. Pharmacol. 149 2 2009 187 195
255. Y.M. Shah K. Morimura Q. Yang T. Tanabe M. Takagi F.J. Gonzalez Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation Mol. Cell. Biol. 27 12 2007 4238 4247
256. X. Shi L.W. Yeung P.K. Lam R.S. Wu B. Zhou Protein profiles in zebrafish (Danio rerio) embryos exposed to perfluorooctane sulfonate Toxicol. Sci. 110 2 2009 334 340
257. S. Shin N. Wakabayashi V. Misra S. Biswal G.H. Lee E.S. Agoston M. Yamamoto T.W. Kensler NRF2 modulates aryl hydrocarbon receptor signaling: Influence on adipogenesis Mol. Cell. Biol. 27 20 2007 7188 7197
258. E. Sim N. Lack C.J. Wang H. Long I. Westwood E. Fullam A. Kawamura Arylamine N-acetyltransferases: Structural and functional implications of polymorphisms Toxicology 254 3 2008 170 183
259. M.K. Skinner M.D. Anway M.I. Savenkova A.C. Gore D. Crews Transgenerational epigenetic programming of the brain transcriptome and anxiety behavior PLoS ONE 3 11 2008 e3745
260. A.R. Soares P.M. Pereira B. Santos C. Egas A.C. Gomes J. Arrais J.L. Oliveira G.R. Moura M.A. Santos Parallel DNA pyrosequencing unveils new zebrafish microRNAs BMC Genomics 10 2009 195
261. W. Song Z. Zou F. Xu X. Gu X. Xu Q. Zhao Molecular cloning and expression of a second zebrafish aldehyde dehydrogenase 2 gene (aldh2b) DNA Seq. 17 4 2006 262 269
262. J.M. Spitsbergen M.L. Kent The state of the art of the zebrafish model for toxicology and toxicologic pathology research -- advantages and current limitations Toxicol. Pathol. 31 Suppl. 2003 62 87
263. J.J. Stegeman Polynuclear aromatic hydrocarbons and their metabolism in the marine environment H.V. Gelboin P.O.P. Ts’o Polycyclic Hydrocarbons and Cancer 3 1981 Academic Press New York 1 60
264. J.J. Stegeman M. Brouwer R.T. DiGiulio L. Forlin B.M. Fowler B.M. Sanders P. Van Veld Molecular responses to environmental contamination: Enzyme and protein systems as indicators of contaminant exposure and effect R.J. Huggett Biomarkers for Chemical Contaminants 1992 CRC Press 237 339
265. J.J. Stegeman R.M. Smolowitz M.E. Hahn Immunohistochemical localization of environmentally induced cytochrome P4501A1 in multiple organs of the marine teleost Stenotomus chrysops (scup) Toxicol. Appl. Pharmacol. 110 1991 486 504
266. J.J. Stegeman B.R. Woodin R.L. Binder Patterns of benzo[a]pyrene metabolism by varied species, organs, and developmental stages of fish Natl Cancer Inst. Monogr. 65 1984 371 377
267. M. Suzawa H.A. Ingraham The herbicide atrazine activates endocrine gene networks via non-steroidal NR5A nuclear receptors in fish and mammalian cells PLoS ONE 3 5 2008 e2117
268. T. Suzuki Y. Takagi H. Osanai L. Li M. Takeuchi Y. Katoh M. Kobayashi M. Yamamoto Pi class glutathione S-transferase genes are regulated by Nrf 2 through an evolutionarily conserved regulatory element in zebrafish Biochem. J. 388 Pt 1 2005 65 73
269. S. Takagi M. Nakajima T. Mohri T. Yokoi Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4 J. Biol. Chem. 283 15 2008 9674 9680
270. Y. Takagi M. Kobayashi L. Li T. Suzuki K. Nishikawa M. Yamamoto MafT, a new member of the small Maf protein family in zebrafish Biochem. Biophys. Res. Commun. 320 1 2004 62 69
271. R.L. Tanguay C.C. Abnet W. Heideman R.E. Peterson Cloning and characterization of the zebrafish (Danio rerio) aryl hydrocarbon receptor Biochim. Biophys. Acta 1444 1 1999 35 48
272. R.L. Tanguay E. Andreasen W. Heideman R.E. Peterson Identification and expression of alternatively spliced aryl hydrocarbon nuclear translocator 2 (ARNT2) cDNAs from zebrafish with distinct functions Biochim. Biophys. Acta 1494 1-2 2000 117 128
273. H. Teraoka W. Dong T. Hiraga Zebrafish as a novel experimental model for developmental toxicology Congenit. Anom. (Kyoto) 43 2 2003 123 132
274. E.J. Thatcher J. Bond I. Paydar J.G. Patton Genomic Organization of Zebrafish microRNAs BMC Genomics 9 2008 253
275. E.J. Thatcher A.S. Flynt N. Li J.R. Patton J.G. Patton MiRNA expression analysis during normal zebrafish development and following inhibition of the hedgehog and notch signaling pathways Dev. Dyn. 236 8 2007 2172 2180
276. E.J. Thatcher I. Paydar K.K. Anderson J.G. Patton Regulation of zebrafish fin regeneration by microRNAs Proc. Natl Acad. Sci. USA 105 47 2008 18384 18389
277. N. Thorsteinson F. Ban O. Santos-Filho S.M. Tabaei S. Miguel-Queralt C. Underhill A. Cherkasov G.L. Hammond In silico identification of anthropogenic chemicals as ligands of zebrafish sex hormone binding globulin Toxicol. Appl. Pharmacol. 234 1 2009 47 57
278. G.M. Tiboni F. Marotta E. Carletti Fluconazole alters CYP26 gene expression in mouse embryos Reprod. Toxicol. 27 2 2009 199 202
279. A.R. Timme-Laragy L.A. Van Tiem E.A. Linney R.T. Di Giulio Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish Toxicol. Sci. 109 2 2009 217 227
280. C. Ton D. Stamatiou C.C. Liew Gene expression profile of zebrafish exposed to hypoxia during development Physiol. Genomics 13 2 2003 97 106
281. Y. Tsuchiya M. Nakajima S. Takagi T. Taniya T. Yokoi MicroRNA regulates the expression of human cytochrome P450 1B1 Cancer Res. 66 18 2006 9090 9098
282. R.H. Tukey C.P. Strassburg Human UDP-glocuronosyltransferases: metabolism, expression, and disease Annu. Rev. Pharmacol. Toxicol. 40 2000 581 616
283. A.J. Udvadia E. Linney Windows into development: Historic, current, and future perspectives on transgenic zebrafish Dev. Biol. 256 1 2003 1 17
284. 60 exposure elicits an oxidative stress response in embryonic zebrafish Toxicol. Appl. Pharmacol. 229 1 2008 44 55
285. A.L. van Boxtel J.H. Kamstra P.H. Cenijn B. Pieterse J.M. Wagner M. Antink K. Krab B. van der Burg G. Marsh A. Brouwer Microarray analysis reveals a mechanism of phenolic polybrominated diphenylether toxicity in zebrafish Environ. Sci. Technol. 42 5 2008 1773 1779
286. K. van der Ven M. De Wit D. Keil L. Moens K. Van Leemput B. Naudts W. De Coen Development and application of a brain-specific cDNA microarray for effect evaluation of neuro-active pharmaceuticals in zebrafish (Danio rerio) Comp. Biochem. Physiol. B Biochem. Mol. Biol. 141 4 2005 408 417
287. K. van der Ven D. Keil L.N. Moens P.V. Hummelen P. van Remortel M. Maras W. De Coen Effects of the antidepressant mianserin in zebrafish: Molecular markers of endocrine disruption Chemosphere 65 10 2006 1836 1845
288. K. van der Ven D. Keil L.N. Moens K. Van Leemput P. van Remortel W.M. De Coen Neuropharmaceuticals in the environment: Mianserin-induced neuroendocrine disruption in zebrafish (Danio rerio) using cDNA microarrays Environ. Toxicol. Chem. 25 10 2006 2645 2652
289. P.A. Van Veld W.K. Vogelbein M.K. Cochran A. Goksoyr J.J. Stegeman Route-specific cellular expression of cytochrome P4501A (CYP1A) in fish (Fundulus heteroclitus) following exposure to aqueous and dietary benzo[a]pyrene Toxicol. Appl. Pharmacol. 142 2 1997 348 359
290. S.G. Vascotto Y. Beckham G.M. Kelly The zebrafish’s swim to fame as an experimental model in biology Biochem. Cell Biol. 75 5 1997 479 485
291. H. Verkade J.K. Heath Wnt signaling mediates diverse developmental processes in zebrafish Methods Mol. Biol. 469 2008 225 251
292. C.M. Vezina T.M. Lin R.E. Peterson AHR signaling in prostate growth, morphogenesis, and disease Biochem. Pharmacol. 77 4 2009 566 576
293. L. Villeneuve R.L. Wang D.C. Bencic A.D. Biales D. Martinovic J.M. Lazorchak G. Toth G.T. Ankley Altered gene expression in the brain and ovaries of zebrafish (Danio rerio) exposed to the aromatase inhibitor fadrozole: Microarray analysis and hypothesis generation Environ. Toxicol. Chem. 28 8 2009 1767 1782
294. D. Voelker C. Vess M. Tillmann R. Nagel G.W. Otto R. Geisler K. Schirmer S. Scholz Differential gene expression as a toxicant-sensitive endpoint in zebrafish embryos and larvae Aquat. Toxicol. 81 4 2007 355 364
295. A. Vogt A. Cholewinski X. Shen S.G. Nelson J.S. Lazo M. Tsang N.A. Hukriede Automated image-based phenotypic analysis in zebrafish embryos Dev. Dyn. 238 3 2009 656 663
296. L. Wang J. Yao L. Chen J. Chen J. Xue W. Jia Expression and possible functional roles of cytochromes P450 2J1 (zfCyp 2J1) in zebrafish Biochem. Biophys. Res. Commun. 352 4 2007 850 855
297. M. Wang L.L. Chan M. Si H. Hong D. Wang Proteomic analysis of hepatic tissue of zebrafish (Danio rerio) experimentally exposed to chronic microcystin-LR Toxicol. Sci. 113 1 2009 60 69
298. R.L. Wang D. Bencic A. Biales D. Lattier M. Kostich D. Villeneuve G.T. Ankley J. Lazorchak G. Toth DNA microarray-based ecotoxicological biomarker discovery in a small fish model species Environ. Toxicol. Chem. 27 3 2008 664 675
299. R.L. Wang A. Biales D. Bencic D. Lattier M. Kostich D. Villeneuve G.T. Ankley J. Lazorchak G. Toth DNA microarray application in ecotoxicology: Experimental design, microarray scanning, and factors affecting transcriptional profiles in a small fish species Environ. Toxicol. Chem. 27 3 2008 652 663
300. Y. Wang U. Wimmer P. Lichtlen D. Inderbitzin B. Stieger P.J. Meier L. Hunziker T. Stallmach R. Forrer T. Rulicke Metal-responsive transcription factor-1 (MTF-1) is essential for embryonic liver development and heavy metal detoxification in the adult liver FASEB J. 18 10 2004 1071 1079
301. K.H. Watanabe K.M. Jensen E.F. Orlando G.T. Ankley What is normal? A characterization of the values and variability in reproductive endpoints of the fathead minnow, Pimephales promelas Comp. Biochem. Physiol. C Toxicol. Pharmacol. 146 3 2007 348 356
302. D.J. Waxman P450 gene induction by structurally diverse xenochemicals: Central role of nuclear receptors CAR, PXR, and PPAR Arch. Biochem. Biophys. 369 1 1999 11 23
303. K.J. Webb W.H. Norton D. Trumbach A.H. Meijer J. Ninkovic S. Topp D. Heck C. Marr W. Wurst F.J. Theis Zebrafish reward mutants reveal novel transcripts mediating the behavioral effects of amphetamine Genome Biol. 10 7 2009 R81
304. P. Wei J. Zhang D.H. Dowhan Y. Han D.D. Moore Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response Pharmacogenom J. 2 2 2002 117 126
305. P.G. Wells G.P. McCallum C.S. Chen J.T. Henderson C.J. Lee J. Perstin T.J. Preston M.J. Wiley A.W. Wong Oxidative stress in developmental origins of disease: Teratogenesis, neurodevelopmental deficits, and cancer Toxicol. Sci. 108 1 2009 4 18
306. J.A. White B. Beckett-Jones Y.D. Guo F.J. Dilworth J. Bonasoro G. Jones M. Petkovich cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450 J. Biol. Chem. 272 30 1997 18538 18541
307. K. Wolfe Robustness – it’s not where you think it is Nat. Genet. 25 1 2000 3 4
308. S.M. Wu Y.D. Zheng C.H. Kuo Expression of mt2 and smt-B upon cadmium exposure and cold shock in zebrafish (Danio rerio) Comp. Biochem. Physiol. C Toxicol. Pharmacol. 148 2 2008 184 193
309. W. Xie J.L. Barwick C.M. Simon A.M. Pierce S. Safe B. Blumberg P.S. Guzelian R.M. Evans Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR Genes. Dev. 14 23 2000 3014 3023
310. K.M. Xiong R.E. Peterson W. Heideman Aryl hydrocarbon receptor-mediated down-regulation of sox9b causes jaw malformation in zebrafish embryos Mol. Pharmacol. 74 6 2008 1544 1553
311. Y. Yamamoto T. Kawamoto M. Negishi The role of the nuclear receptor CAR as a coordinate regulator of hepatic gene expression in defense against chemical toxicity Arch. Biochem. Biophys. 409 1 2003 207 211
312. C.H. Yan K.M. Chan Characterization of zebrafish metallothionein gene promoter in a zebrafish caudal fin cell-line, SJD. 1 Mar. Environ. Res. 54 3-5 2002 335 339
313. C.H. Yan K.M. Chan Cloning of zebrafish metallothionein gene and characterization of its gene promoter region in HepG2 cell line Biochim. Biophys. Acta 1679 1 2004 47 58
314. L. Yang J.R. Kemadjou C. Zinsmeister M. Bauer J. Legradi F. Muller M. Pankratz J. Jakel U. Strahle Transcriptional profiling reveals barcode-like toxicogenomic responses in the zebrafish embryo Genome Biol. 8 10 2007 R227
315. S. Yasuda A.P. Kumar M.Y. Liu Y. Sakakibara M. Suiko L. Chen M.C. Liu Identification of a novel thyroid hormone-sulfating cytosolic sulfotransferase, SULT1 ST5, from zebrafish FEBS J. 272 15 2005 3828 3837
316. S. Yasuda C.C. Liu S. Takahashi M. Suiko L. Chen R. Snow M.C. Liu Identification of a novel estrogen-sulfating cytosolic SULT from zebrafish: Molecular cloning, expression, characterization, and ontogeny study Biochem. Biophys. Res. Commun. 330 1 2005 219 225
317. T. Yasuda S. Yasuda F.E. Williams M.Y. Liu Y. Sakakibara S. Bhuiyan R. Snow G. Carter M.C. Liu Characterization and ontogenic study of novel steroid-sulfating SULT3 sulfotransferases from zebrafish Mol. Cell. Endocrinol. 294 1-2 2008 29 36
318. R.L. Yeager S.A. Reisman L.M. Aleksunes C.D. Klaassen Introducing the ‘TCDD Inducible AhR-Nrf2 Gene Battery’ Toxicol. Sci. 11 2 2009 238 246
319. H.C. Yin H.P. Tseng H.Y. Chung C.Y. Ko W.S. Tzou D.R. Buhler C.H. Hu Influence of TCDD on zebrafish CYP1B1 transcription during development Toxicol. Sci. 103 1 2008 158 168
320. D. Zheng G.P. Feeney P. Kille C. Hogstrand Regulation of ZIP and ZnT zinc transporters in zebrafish gill: Zinc repression of ZIP10 transcription by an intronic MRE cluster Physiol. Genomics 34 2 2008 205 214
321. 60) and fullerol Environ. Toxicol. Chem. 26 5 2007 976 979
322. D.M. Ziegler An overview of the mechanism, substrate specificities, and structure of FMOs Drug Metab. Rev. 34 3 2002 503 511
323. J.M. Zodrow J.J. Stegeman R.L. Tanguay Histological analysis of acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in zebrafish Aquat. Toxicol. 66 1 2004 25 38