Altered gene expression in the brain and ovaries of zebrafish (Danio rerio) exposed to the aromatase inhibitor fadrozole: Microarray analysis and hypothesis generation

Environmental Toxicology and Chemistry

Volumn 28, Issue 8, 2009, Pages 1767-1782

  Villeneuve, Daniel L ^a   Wang, Rong Lin ^a   Bencic, David C ^a   Biales, Adam D ^a   Martinović, Dalma ^a   Lazorchak, James M ^a   Toth, Gregory ^a   Ankley, Gerald T ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Endocrine disruption; Fish; Neurotoxicity; Reproduction; Transcriptomics

Indexed keywords

ACTIVE CHEMICALS; ALCOHOL DEHYDROGENASE; AROMATASE; BINDING FACTORS; BRAIN TISSUE; CARBON POOL; CELL CYCLE; CELL-CELL ADHESION; CHEMICAL STRESSORS; COEXPRESSED GENES; DANIO RERIO; DIFFERENT MODES; DNA REPLICATIONS; ENDOCRINE DISRUPTION; EXTRACELLULAR MATRICES; GENE REGULATORS; GLIAL CELLS; HEAT SHOCK FACTORS; HYPOTHESIS GENERATION; IN-CONTROL; MICROARRAY ANALYSIS; MOTIF ANALYSIS; MULTIPLE GENES; MYOBLASTS; NEURODEGENERATIVE; NEUROTOXICITY; OLIGONUCLEOTIDE MICROARRAY; OOCYTE MATURATION; OVARIAN TISSUE; REPRODUCTION; RESEARCH EFFORTS; TRANSCRIPTIONAL CHANGES; TRANSCRIPTIONAL RESPONSE; TRANSCRIPTOMICS; VASCULOGENESIS; ZEBRAFISH;

ADHESION; BIOACTIVITY; CELL ADHESION; CELL MEMBRANES; GENE EXPRESSION; MEATS; NUCLEIC ACIDS; OLIGONUCLEOTIDES;

FISH;

ALCOHOL DEHYDROGENASE; AROMATASE INHIBITOR; FADROZOLE; IKAROS TRANSCRIPTION FACTOR; OLIGONUCLEOTIDE; TRANSCRIPTION FACTOR GATA 2;

ARRAY; BRAIN; CYPRINID; DRUG; ENDOCRINE DISRUPTOR; ENZYME ACTIVITY; GENE EXPRESSION; HYPOTHESIS TESTING; INHIBITOR; REPRODUCTION;

ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; BRAIN; CELL ADHESION; CELL CYCLE; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA MICROARRAY; DNA REPLICATION; EXTRACELLULAR MATRIX; FEMALE; GENE CLUSTER; GENE EXPRESSION; GENETIC TRANSCRIPTION; GLIA CELL; HEAT SHOCK; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MICROARRAY ANALYSIS; NERVE DEGENERATION; NONHUMAN; OOCYTE MATURATION; OVARY; OVULATION; PRIORITY JOURNAL; UPREGULATION; VITELLOGENESIS; ZEBRA FISH;

ANIMALS; AROMATASE INHIBITORS; BRAIN; FADROZOLE; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MALE; OVARY; PROMOTER REGIONS, GENETIC; PROTEIN ARRAY ANALYSIS; ZEBRAFISH;

DANIO RERIO;

EID: 69049113953     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1897/08-653.1     Document Type: Article

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