메뉴 건너뛰기




Volumn 149, Issue 2, 2009, Pages 187-195

Zebrafish (Danio rerio) as a model organism for investigating endocrine disruption

Author keywords

Endocrine disruption; Model organism; Zebrafish

Indexed keywords

ENDOCRINE DISRUPTOR; ETHINYLESTRADIOL; SEX HORMONE; VITELLOGENIN;

EID: 63749106101     PISSN: 15320456     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbpc.2008.10.099     Document Type: Review
Times cited : (257)

References (113)
  • 2
    • 0642339677 scopus 로고    scopus 로고
    • Effects of exposure to 17α-ethinylestradiol during early development on sexual differentiation and induction of vitellogenin in zebrafish (Danio rerio)
    • Andersen L., Holbech H., Gessbo A., Norrgren L., and Petersen G.I. Effects of exposure to 17α-ethinylestradiol during early development on sexual differentiation and induction of vitellogenin in zebrafish (Danio rerio). Comp. Biochem. Physiol. C 134 (2003) 365-374
    • (2003) Comp. Biochem. Physiol. C , vol.134 , pp. 365-374
    • Andersen, L.1    Holbech, H.2    Gessbo, A.3    Norrgren, L.4    Petersen, G.I.5
  • 3
    • 32644487401 scopus 로고    scopus 로고
    • Short-term exposure to low concentrations of the synthetic androgen methyltestosterone affects vitellogenin and steroid levels in adult male zebrafish
    • Andersen L., Goto-Kazeto R., Trant J.M., Nash J.P., Korsgaard B., and Bjerregard P. Short-term exposure to low concentrations of the synthetic androgen methyltestosterone affects vitellogenin and steroid levels in adult male zebrafish. Aquat. Toxicol. 76 (2006) 343-352
    • (2006) Aquat. Toxicol. , vol.76 , pp. 343-352
    • Andersen, L.1    Goto-Kazeto, R.2    Trant, J.M.3    Nash, J.P.4    Korsgaard, B.5    Bjerregard, P.6
  • 4
    • 8144226890 scopus 로고    scopus 로고
    • Small fish models for identifying and assessing the effects of endocrine disrupting chemicals
    • Ankley G.T., and Johnson R.D. Small fish models for identifying and assessing the effects of endocrine disrupting chemicals. ILAR J. 45 (2004) 469-483
    • (2004) ILAR J. , vol.45 , pp. 469-483
    • Ankley, G.T.1    Johnson, R.D.2
  • 5
    • 2942547979 scopus 로고    scopus 로고
    • Eggshell and egg yolk proteins in fish: hepatic proteins for the next generation: oogenetic, population, and evolutionary implications of endocrine disruption
    • Arukwe A., and Goksoyr A. Eggshell and egg yolk proteins in fish: hepatic proteins for the next generation: oogenetic, population, and evolutionary implications of endocrine disruption. Comp. Hepatol. 2 (2003) 4
    • (2003) Comp. Hepatol. , vol.2 , pp. 4
    • Arukwe, A.1    Goksoyr, A.2
  • 6
    • 31244436879 scopus 로고    scopus 로고
    • Alterations to gonadal and reproductive success in Japanese medaka exposed to 17α-ethinylestradiol
    • Balch G.C., Mackenzie C.A., and Metcalfe C.D. Alterations to gonadal and reproductive success in Japanese medaka exposed to 17α-ethinylestradiol. Environ. Toxicol. Chem. 23 (2004) 782-791
    • (2004) Environ. Toxicol. Chem. , vol.23 , pp. 782-791
    • Balch, G.C.1    Mackenzie, C.A.2    Metcalfe, C.D.3
  • 9
    • 20444442846 scopus 로고    scopus 로고
    • Estrogen increases sensory nociceptor neurogenesis in vitro by a direct, nerve growth factor-independent mechanism
    • Blacklock A.D., Johnson M.S., Krizsan-Agbas D., and Smith P.G. Estrogen increases sensory nociceptor neurogenesis in vitro by a direct, nerve growth factor-independent mechanism. Eur. J. Neurosci. 21 (2005) 2320-2328
    • (2005) Eur. J. Neurosci. , vol.21 , pp. 2320-2328
    • Blacklock, A.D.1    Johnson, M.S.2    Krizsan-Agbas, D.3    Smith, P.G.4
  • 10
    • 29844438526 scopus 로고    scopus 로고
    • Estrogenic endpoints in fish early life stage tests: luciferase and vitellogenin induction in estrogen-responsive transgenic zebrafish
    • Bogers R., Mutsaerds E., Druke J., de Rode D.F., Murk A.J., van der Burg B., and Legler J. Estrogenic endpoints in fish early life stage tests: luciferase and vitellogenin induction in estrogen-responsive transgenic zebrafish. Environ. Toxicol. Chem. 25 (2006) 241-247
    • (2006) Environ. Toxicol. Chem. , vol.25 , pp. 241-247
    • Bogers, R.1    Mutsaerds, E.2    Druke, J.3    de Rode, D.F.4    Murk, A.J.5    van der Burg, B.6    Legler, J.7
  • 11
    • 22144477546 scopus 로고    scopus 로고
    • Towards an alternative for the acute fish LC50 test in chemical assessment: the fish embryo toxicity test goes multi-species-an update
    • Braunbeck T., Böttcher M., Hollert H., Kosmehl T., Lammer E., Leist E., Rudolf M., and Seitz N. Towards an alternative for the acute fish LC50 test in chemical assessment: the fish embryo toxicity test goes multi-species-an update. ALTEX 22 (2005) 87-102
    • (2005) ALTEX , vol.22 , pp. 87-102
    • Braunbeck, T.1    Böttcher, M.2    Hollert, H.3    Kosmehl, T.4    Lammer, E.5    Leist, E.6    Rudolf, M.7    Seitz, N.8
  • 12
    • 0025285804 scopus 로고
    • A long-term toxicity test comprising reproduction and growth of zebrafish with 4-chloroaniline
    • Bresch H., Beck H., Ehlermann D., Schlaszus H., and Urbanek M. A long-term toxicity test comprising reproduction and growth of zebrafish with 4-chloroaniline. Arch. Environ. Contam. Toxicol. 19 (1990) 419-427
    • (1990) Arch. Environ. Contam. Toxicol. , vol.19 , pp. 419-427
    • Bresch, H.1    Beck, H.2    Ehlermann, D.3    Schlaszus, H.4    Urbanek, M.5
  • 13
    • 0035992455 scopus 로고    scopus 로고
    • Development and validation of an enzyme-linked immunosorbent assays to measure vitellogenin in the zebrafish (Danio rerio)
    • Brion F., Nilsen B.M., Eidem J.K., Goksoyr A., and Porcher J.M. Development and validation of an enzyme-linked immunosorbent assays to measure vitellogenin in the zebrafish (Danio rerio). Environ. Toxicol. Chem. 21 (2002) 1699-1708
    • (2002) Environ. Toxicol. Chem. , vol.21 , pp. 1699-1708
    • Brion, F.1    Nilsen, B.M.2    Eidem, J.K.3    Goksoyr, A.4    Porcher, J.M.5
  • 14
    • 2542420854 scopus 로고    scopus 로고
    • Impacts of 17β-estradiol, including environmentally relevant concentrations, on reproduction after exposure during embryo-larval, juvenile and adult life stages in zebrafish (Danio rerio)
    • Brion F., Tyler C.R., Palazzi X., Laillet B., Porcher J.M., Garric J., and Flammarion P. Impacts of 17β-estradiol, including environmentally relevant concentrations, on reproduction after exposure during embryo-larval, juvenile and adult life stages in zebrafish (Danio rerio). Aquat. Toxicol. 68 (2004) 193-217
    • (2004) Aquat. Toxicol. , vol.68 , pp. 193-217
    • Brion, F.1    Tyler, C.R.2    Palazzi, X.3    Laillet, B.4    Porcher, J.M.5    Garric, J.6    Flammarion, P.7
  • 16
    • 77957053072 scopus 로고    scopus 로고
    • The utility of zebrafish as a model for toxicological research
    • Mommsen T.P., and Moon T.W. (Eds), Elsevier, Amsterdam
    • Carvan M.J., Heiden T.K., and Tomasiewicz H. The utility of zebrafish as a model for toxicological research. In: Mommsen T.P., and Moon T.W. (Eds). Biochemistry and Molecular Biology of Fishes vol. 6 (2005), Elsevier, Amsterdam 3-41
    • (2005) Biochemistry and Molecular Biology of Fishes , vol.6 , pp. 3-41
    • Carvan, M.J.1    Heiden, T.K.2    Tomasiewicz, H.3
  • 17
    • 33751512673 scopus 로고    scopus 로고
    • Transgenerational epigenetic imprinting of the male germline by endocrine disruptor exposure during gonadal sex determination
    • Chang H.S., Anway M.D., Rekow S.S., and Skinner M.K. Transgenerational epigenetic imprinting of the male germline by endocrine disruptor exposure during gonadal sex determination. Endocrinology 147 (2006) 5524-5541
    • (2006) Endocrinology , vol.147 , pp. 5524-5541
    • Chang, H.S.1    Anway, M.D.2    Rekow, S.S.3    Skinner, M.K.4
  • 19
    • 33947264141 scopus 로고    scopus 로고
    • Expression of zebrafish aromatase cyp19a and cyp19b genes in response to the ligands of estrogen receptor and aryl hydrocarbon receptor
    • Cheshenko K., Brion F., Le Page Y., Hinfray N., Pakdel F., Kah O., Segner H., and Eggen R.I.L. Expression of zebrafish aromatase cyp19a and cyp19b genes in response to the ligands of estrogen receptor and aryl hydrocarbon receptor. Toxicol. Sci. 96 (2007) 255-267
    • (2007) Toxicol. Sci. , vol.96 , pp. 255-267
    • Cheshenko, K.1    Brion, F.2    Le Page, Y.3    Hinfray, N.4    Pakdel, F.5    Kah, O.6    Segner, H.7    Eggen, R.I.L.8
  • 20
    • 36249008052 scopus 로고    scopus 로고
    • Interference of endocrine disrupting chemicals with aromatase CYP19 expression or activity, and consequences for reproduction of teleost fish
    • Cheshenko K., Pakdel F., Segner H., Kah O., and Eggen R.I.L. Interference of endocrine disrupting chemicals with aromatase CYP19 expression or activity, and consequences for reproduction of teleost fish. Gen. Comp. Endocrinol. 155 (2008) 31-62
    • (2008) Gen. Comp. Endocrinol. , vol.155 , pp. 31-62
    • Cheshenko, K.1    Pakdel, F.2    Segner, H.3    Kah, O.4    Eggen, R.I.L.5
  • 21
    • 0027428381 scopus 로고
    • Developmental effects of endocrine-disrupting chemicals in wildlife and humans
    • Colborn T., vom Saal F.S., and Soto A.M. Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environ. Health Perspect. 101 (1993) 378-384
    • (1993) Environ. Health Perspect. , vol.101 , pp. 378-384
    • Colborn, T.1    vom Saal, F.S.2    Soto, A.M.3
  • 22
    • 0742323820 scopus 로고    scopus 로고
    • The lateral line system for the analysis of morphogenesis and neural development in vertebrates
    • Dambly-Chaudiére C., Sapède D., Soubiran F., Decorde K., Gompel N., and Ghysen A. The lateral line system for the analysis of morphogenesis and neural development in vertebrates. Biol. Cell 95 (2003) 579-587
    • (2003) Biol. Cell , vol.95 , pp. 579-587
    • Dambly-Chaudiére, C.1    Sapède, D.2    Soubiran, F.3    Decorde, K.4    Gompel, N.5    Ghysen, A.6
  • 23
    • 0019745450 scopus 로고
    • Toxicity of eight solvent extraction chemicals and of cadmium to water fleas, Daphnia magna, rainbow trout, Salmo gairdneri, and zebrafish, Brachydanio rerio
    • Dave G., Andersson K., Berglind R., and Hasselrot B. Toxicity of eight solvent extraction chemicals and of cadmium to water fleas, Daphnia magna, rainbow trout, Salmo gairdneri, and zebrafish, Brachydanio rerio. Comp. Biochem. Physiol. C 69 (1981) 83-98
    • (1981) Comp. Biochem. Physiol. C , vol.69 , pp. 83-98
    • Dave, G.1    Andersson, K.2    Berglind, R.3    Hasselrot, B.4
  • 24
    • 0037150614 scopus 로고    scopus 로고
    • Sex determination and sex differentiation in fish: an overview of genetic, physiological and environmental influences
    • Devlin R.H., and Nagahama Y. Sex determination and sex differentiation in fish: an overview of genetic, physiological and environmental influences. Aquaculture 208 (2002) 191-364
    • (2002) Aquaculture , vol.208 , pp. 191-364
    • Devlin, R.H.1    Nagahama, Y.2
  • 26
    • 0034068307 scopus 로고    scopus 로고
    • Zebrafish: a model system for the study of human disease
    • Dooley K., and Zon L.I. Zebrafish: a model system for the study of human disease. Curr. Opin. Genet. Dev. 10 (2000) 252-256
    • (2000) Curr. Opin. Genet. Dev. , vol.10 , pp. 252-256
    • Dooley, K.1    Zon, L.I.2
  • 28
    • 34248149018 scopus 로고    scopus 로고
    • Larval zebrafish as a model for glucose metabolism: expression of phosphoenoly pyruvate carboxykinase as a marker for exposure to anti-diabetic compounds
    • Elo B., Viallano C.M., Govorko D., and White L.A. Larval zebrafish as a model for glucose metabolism: expression of phosphoenoly pyruvate carboxykinase as a marker for exposure to anti-diabetic compounds. J. Mol. Endocrinol. 38 (2007) 433-440
    • (2007) J. Mol. Endocrinol. , vol.38 , pp. 433-440
    • Elo, B.1    Viallano, C.M.2    Govorko, D.3    White, L.A.4
  • 29
    • 1542375216 scopus 로고    scopus 로고
    • Aromatase modulation alters gonadal differentiation in developing zebrafish (Danio rerio)
    • Fenske M., and Segner H. Aromatase modulation alters gonadal differentiation in developing zebrafish (Danio rerio). Aquat. Toxicol. 67 (2004) 105-126
    • (2004) Aquat. Toxicol. , vol.67 , pp. 105-126
    • Fenske, M.1    Segner, H.2
  • 30
    • 0034924999 scopus 로고    scopus 로고
    • Development and validation of a homologous zebrafish vitellogenin ELISA and its application for studies on estrogenic chemicals
    • Fenske M., van Aerle R., Brack S., Tyler C.R., and Segner H. Development and validation of a homologous zebrafish vitellogenin ELISA and its application for studies on estrogenic chemicals. Comp. Biochem. Physiol. C 129 (2001) 217-232
    • (2001) Comp. Biochem. Physiol. C , vol.129 , pp. 217-232
    • Fenske, M.1    van Aerle, R.2    Brack, S.3    Tyler, C.R.4    Segner, H.5
  • 31
    • 18244367401 scopus 로고    scopus 로고
    • An environmentally relevant concentration of ethinylestradiol induces arrest of male gonad development in zebrafish, Danio rerio
    • Fenske M., Maack G., Schäfers C., and Segner H. An environmentally relevant concentration of ethinylestradiol induces arrest of male gonad development in zebrafish, Danio rerio. Environ. Toxicol. Chem. 24 (2005) 1088-1098
    • (2005) Environ. Toxicol. Chem. , vol.24 , pp. 1088-1098
    • Fenske, M.1    Maack, G.2    Schäfers, C.3    Segner, H.4
  • 32
    • 34547844592 scopus 로고    scopus 로고
    • Late lessons from early warnings: toward realism and precaution with endocrine-disrupting substances
    • Gee D. Late lessons from early warnings: toward realism and precaution with endocrine-disrupting substances. Environ. Health Perspect. 114 suppl. 1 (2006) 152-160
    • (2006) Environ. Health Perspect. , vol.114 , Issue.SUPPL. 1 , pp. 152-160
    • Gee, D.1
  • 33
    • 13444272394 scopus 로고    scopus 로고
    • Zebrafish as a pharmacological tool: the how, why, and when
    • Goldsmith P. Zebrafish as a pharmacological tool: the how, why, and when. Curr. Opin. Pharmacol. 4 (2004) 1-9
    • (2004) Curr. Opin. Pharmacol. , vol.4 , pp. 1-9
    • Goldsmith, P.1
  • 34
    • 34249824339 scopus 로고    scopus 로고
    • Endocrine-disrupting contaminants-beyond the dogma
    • Guillette L.J. Endocrine-disrupting contaminants-beyond the dogma. Environ. Health Perspect 114 suppl 1 (2006) 9-12
    • (2006) Environ. Health Perspect , vol.114 , Issue.SUPPL. 1 , pp. 9-12
    • Guillette, L.J.1
  • 37
    • 0038613104 scopus 로고    scopus 로고
    • Developmental estrogenic exposure in zebrafish (Danio rerio). I. Effects on sex ratio and breeding success
    • Hill R.L., and Janz D.M. Developmental estrogenic exposure in zebrafish (Danio rerio). I. Effects on sex ratio and breeding success. Aquat. Toxicol. 63 (2003) 417-429
    • (2003) Aquat. Toxicol. , vol.63 , pp. 417-429
    • Hill, R.L.1    Janz, D.M.2
  • 38
    • 26944441684 scopus 로고    scopus 로고
    • Zebrafish as a model vertebrate for investigating chemical toxicity
    • Hill A.J., Teraoka H., Heideman W., and Peterson R.E. Zebrafish as a model vertebrate for investigating chemical toxicity. Toxicol. Sci. 86 (2005) 6-19
    • (2005) Toxicol. Sci. , vol.86 , pp. 6-19
    • Hill, A.J.1    Teraoka, H.2    Heideman, W.3    Peterson, R.E.4
  • 43
    • 34447105988 scopus 로고    scopus 로고
    • Expression of endocrine genes in zebrafish larvae in response to environmental salinity
    • Hoshijima K., and Hirose S. Expression of endocrine genes in zebrafish larvae in response to environmental salinity. J. Endocrinol. 193 (2007) 481-491
    • (2007) J. Endocrinol. , vol.193 , pp. 481-491
    • Hoshijima, K.1    Hirose, S.2
  • 44
    • 33746730199 scopus 로고    scopus 로고
    • Screening and testing for endocrine disruption in fish-biomarkers as "signposts" not "traffic lights" in risk assessment.
    • Hutchinson T., Ankley G.T., Segner H., and Tyler C.R. Screening and testing for endocrine disruption in fish-biomarkers as "signposts" not "traffic lights" in risk assessment. Environ. Health Perspect. 114 supplement 1 (2006) 106-114
    • (2006) Environ. Health Perspect. , vol.114 , Issue.SUPPL. 1 , pp. 106-114
    • Hutchinson, T.1    Ankley, G.T.2    Segner, H.3    Tyler, C.R.4
  • 45
    • 0037462269 scopus 로고    scopus 로고
    • Effects of 17α-ethinylestradiol on the expression of three estrogen-responsive genes and cellular ultrastructure of liver and testes in male zebrafish
    • Islinger M., Willimski D., Völkl A., and Braunbeck T. Effects of 17α-ethinylestradiol on the expression of three estrogen-responsive genes and cellular ultrastructure of liver and testes in male zebrafish. Aquat. Toxicol. 62 (2003) 85-103
    • (2003) Aquat. Toxicol. , vol.62 , pp. 85-103
    • Islinger, M.1    Willimski, D.2    Völkl, A.3    Braunbeck, T.4
  • 46
    • 0347134693 scopus 로고    scopus 로고
    • Endocrine disruption in wild freshwater fish
    • Jobling S., and Tyler C.R. Endocrine disruption in wild freshwater fish. Pure Appl. Chem. 75 (2003) 2219-2234
    • (2003) Pure Appl. Chem. , vol.75 , pp. 2219-2234
    • Jobling, S.1    Tyler, C.R.2
  • 47
    • 36448979871 scopus 로고    scopus 로고
    • The zebrafish brain-specific aromatase, cyp19a2, is neither expressed nor distributed in a sexually dimorphic manner during sexual differentiation
    • Kallivretaki E., Eggen R.I.L., Neuhauss S.C.F., Kah O., and Segner H. The zebrafish brain-specific aromatase, cyp19a2, is neither expressed nor distributed in a sexually dimorphic manner during sexual differentiation. Dev. Dyn. 236 (2007) 3155-3166
    • (2007) Dev. Dyn. , vol.236 , pp. 3155-3166
    • Kallivretaki, E.1    Eggen, R.I.L.2    Neuhauss, S.C.F.3    Kah, O.4    Segner, H.5
  • 49
    • 2942733417 scopus 로고    scopus 로고
    • Effects of endocrine disrupting chemicals on the expression of CYP19 genes in zebrafish (Danio rerio) juveniles
    • Kazeto Y., Place A.R., and Trant J.M. Effects of endocrine disrupting chemicals on the expression of CYP19 genes in zebrafish (Danio rerio) juveniles. Aquat. Toxicol 69 (2004) 25-34
    • (2004) Aquat. Toxicol , vol.69 , pp. 25-34
    • Kazeto, Y.1    Place, A.R.2    Trant, J.M.3
  • 50
    • 0034982734 scopus 로고    scopus 로고
    • Estrogen and xenoestrogens upregulate the brain aromatase isoform (P450aromB) and perturb markers of early development in zebrafish (Danio rerio)
    • Kishida M., McLellan M., Miranda J.A., and Callard G.V. Estrogen and xenoestrogens upregulate the brain aromatase isoform (P450aromB) and perturb markers of early development in zebrafish (Danio rerio). Comp. Biochem. Physiol., B 129 (2001) 261-268
    • (2001) Comp. Biochem. Physiol., B , vol.129 , pp. 261-268
    • Kishida, M.1    McLellan, M.2    Miranda, J.A.3    Callard, G.V.4
  • 51
    • 18844379680 scopus 로고    scopus 로고
    • Zebrafish gonadotropins and their receptors: I. Cloning and characterization of zebrafish follicle-stimulating hormone and luteinizing hormone receptors-evidence for their distinct functions in follicle development
    • Kwok H.F., So W.K., Wang Y., and Ge W. Zebrafish gonadotropins and their receptors: I. Cloning and characterization of zebrafish follicle-stimulating hormone and luteinizing hormone receptors-evidence for their distinct functions in follicle development. Biol. Reprod. 72 (2005) 1370-1381
    • (2005) Biol. Reprod. , vol.72 , pp. 1370-1381
    • Kwok, H.F.1    So, W.K.2    Wang, Y.3    Ge, W.4
  • 52
    • 0037082553 scopus 로고    scopus 로고
    • Zebrafish as a model for vertebrate reproduction: characterization of the first functional zebrafish (Danio rerio) gonadotropin receptor
    • Laan M., Richmond H., He C., and Campbell R.K. Zebrafish as a model for vertebrate reproduction: characterization of the first functional zebrafish (Danio rerio) gonadotropin receptor. Gen. Comp. Endocrinol. 125 (2002) 349-364
    • (2002) Gen. Comp. Endocrinol. , vol.125 , pp. 349-364
    • Laan, M.1    Richmond, H.2    He, C.3    Campbell, R.K.4
  • 55
    • 33846867001 scopus 로고    scopus 로고
    • Growth differentiation factor 9 and its spatiotemporal expression and regulation in the zebrafish ovary
    • Liu L., and We G. Growth differentiation factor 9 and its spatiotemporal expression and regulation in the zebrafish ovary. Biol. Reprod. 76 (2007) 294-301
    • (2007) Biol. Reprod. , vol.76 , pp. 294-301
    • Liu, L.1    We, G.2
  • 56
    • 4644285301 scopus 로고    scopus 로고
    • Strain-dependent effects of developmental ethanol exposure in zebrafish
    • Loucks E., and Carvan III M.J. Strain-dependent effects of developmental ethanol exposure in zebrafish. Neurotoxicol. Teratol. 26 (2004) 745-755
    • (2004) Neurotoxicol. Teratol. , vol.26 , pp. 745-755
    • Loucks, E.1    Carvan III, M.J.2
  • 57
    • 0033643992 scopus 로고    scopus 로고
    • Transgenic zebrafish
    • Lin S. Transgenic zebrafish. Methods Mol. Biol. 136 (2000) 375-383
    • (2000) Methods Mol. Biol. , vol.136 , pp. 375-383
    • Lin, S.1
  • 58
    • 1442266451 scopus 로고    scopus 로고
    • Morphological development of the gonads in zebrafish
    • Maack G., and Segner H. Morphological development of the gonads in zebrafish. J. Fish Biol. 62 (2003) 895-906
    • (2003) J. Fish Biol. , vol.62 , pp. 895-906
    • Maack, G.1    Segner, H.2
  • 59
    • 8844248618 scopus 로고    scopus 로고
    • Life stage-dependent sensitivity of zebrafish (Danio rerio) to estrogen exposure
    • Maack G., and Segner H. Life stage-dependent sensitivity of zebrafish (Danio rerio) to estrogen exposure. Comp. Biochem. Physiol. C 139 (2004) 47-55
    • (2004) Comp. Biochem. Physiol. C , vol.139 , pp. 47-55
    • Maack, G.1    Segner, H.2
  • 60
    • 33645109254 scopus 로고    scopus 로고
    • Estrogen-dependent selectivity of genomic responses to birdsong
    • Maney D.L., Cho E., and Goode C.T. Estrogen-dependent selectivity of genomic responses to birdsong. Eur. J. Neurosci. 23 (2006) 1523-1529
    • (2006) Eur. J. Neurosci. , vol.23 , pp. 1523-1529
    • Maney, D.L.1    Cho, E.2    Goode, C.T.3
  • 61
    • 34547104388 scopus 로고    scopus 로고
    • Microarray analysis in the zebrafish liver and telencephalon after exposure to low concentration of 17alpha-ethinylestradiol
    • Martinyuk C.J., Gerrie E.R., Popesku J.T., Ekker M., and Trudeau V.L. Microarray analysis in the zebrafish liver and telencephalon after exposure to low concentration of 17alpha-ethinylestradiol. Aquat. Toxicol. 84 (2007) 38-49
    • (2007) Aquat. Toxicol. , vol.84 , pp. 38-49
    • Martinyuk, C.J.1    Gerrie, E.R.2    Popesku, J.T.3    Ekker, M.4    Trudeau, V.L.5
  • 62
    • 0041833393 scopus 로고    scopus 로고
    • Life exposure to environmental levels of the aromatase inhibitor tributyltin causes masculinisation and irreversible sperm damage in zebrafish (Danio rerio)
    • McAllister B.G., and Kime D.E. Life exposure to environmental levels of the aromatase inhibitor tributyltin causes masculinisation and irreversible sperm damage in zebrafish (Danio rerio). Aquat. Toxicol. 65 (2003) 309-316
    • (2003) Aquat. Toxicol. , vol.65 , pp. 309-316
    • McAllister, B.G.1    Kime, D.E.2
  • 63
    • 33745233050 scopus 로고    scopus 로고
    • Fishing for gene function-endocrine modelling in the zebrafish
    • McGonnell I.M., and Fowkes R.C. Fishing for gene function-endocrine modelling in the zebrafish. J. Endocrinol. 189 (2006) 425-439
    • (2006) J. Endocrinol. , vol.189 , pp. 425-439
    • McGonnell, I.M.1    Fowkes, R.C.2
  • 64
    • 0038340910 scopus 로고    scopus 로고
    • Distribution of aromatase mRNA and protein in the brain and pituitary of female rainbow trout: comparison with estrogen receptor alpha
    • Menuet A., Anglade I., Le Guevel R., Pellegrini E., Pakdel F., and Kah O. Distribution of aromatase mRNA and protein in the brain and pituitary of female rainbow trout: comparison with estrogen receptor alpha. J. Comp. Neurol. 462 (2003) 180-193
    • (2003) J. Comp. Neurol. , vol.462 , pp. 180-193
    • Menuet, A.1    Anglade, I.2    Le Guevel, R.3    Pellegrini, E.4    Pakdel, F.5    Kah, O.6
  • 65
    • 4544291383 scopus 로고    scopus 로고
    • Global changes in genomic methylation levels during early development of the zebrafish embryo
    • Mhanni A.A., and McGowan R.A. Global changes in genomic methylation levels during early development of the zebrafish embryo. Dev. Genes Evol. 214 (2004) 412-417
    • (2004) Dev. Genes Evol. , vol.214 , pp. 412-417
    • Mhanni, A.A.1    McGowan, R.A.2
  • 66
    • 34047098017 scopus 로고    scopus 로고
    • Linkage of biochemical responses to population-level effects: a case study with vitellogenin in the fathead minnow (Pimephales promelas)
    • Miller D.H., Jensen K.M., Viellenuve D.L., Kahl M.D., Mykynen E.A., Durhan E.J., and Ankley G.T. Linkage of biochemical responses to population-level effects: a case study with vitellogenin in the fathead minnow (Pimephales promelas). Environ. Toxicol. Chem. 26 (2007) 521-527
    • (2007) Environ. Toxicol. Chem. , vol.26 , pp. 521-527
    • Miller, D.H.1    Jensen, K.M.2    Viellenuve, D.L.3    Kahl, M.D.4    Mykynen, E.A.5    Durhan, E.J.6    Ankley, G.T.7
  • 67
    • 0027213640 scopus 로고
    • Mutational approaches to studying embryonic pattern formation in the zebrafish
    • Mullins M., and Nüsslein-Volhard C. Mutational approaches to studying embryonic pattern formation in the zebrafish. Curr. Opin. Genet. Dev. 3 (1993) 648-654
    • (1993) Curr. Opin. Genet. Dev. , vol.3 , pp. 648-654
    • Mullins, M.1    Nüsslein-Volhard, C.2
  • 68
    • 33845392576 scopus 로고    scopus 로고
    • Vitellogenin 1 mRNA as an early molecular biomarker for endocrine disruption in developing zebrafish (Danio rerio)
    • Muncke J., and Eggen R.I.L. Vitellogenin 1 mRNA as an early molecular biomarker for endocrine disruption in developing zebrafish (Danio rerio). Environ. Toxicol. Chem. 25 (2006) 2734-2741
    • (2006) Environ. Toxicol. Chem. , vol.25 , pp. 2734-2741
    • Muncke, J.1    Eggen, R.I.L.2
  • 69
    • 34047124260 scopus 로고    scopus 로고
    • Testing estrogenicity of known and novel (xeno-)estrogens in the MolDarT using developing zebrafish (Danio rerio)
    • Muncke J., Junghans M., and Eggen R.I.L. Testing estrogenicity of known and novel (xeno-)estrogens in the MolDarT using developing zebrafish (Danio rerio). Environ. Toxicol. 22 (2007) 185-193
    • (2007) Environ. Toxicol. , vol.22 , pp. 185-193
    • Muncke, J.1    Junghans, M.2    Eggen, R.I.L.3
  • 70
    • 3042646762 scopus 로고    scopus 로고
    • 17β-estradiol enhances neuronal differentiation of mouse embryonic stem cells
    • Murashov A.K., Pak E.S., Hendricks W.A., and Tatko L.M. 17β-estradiol enhances neuronal differentiation of mouse embryonic stem cells. FEBS Lett. 569 (2004) 165-168
    • (2004) FEBS Lett. , vol.569 , pp. 165-168
    • Murashov, A.K.1    Pak, E.S.2    Hendricks, W.A.3    Tatko, L.M.4
  • 71
    • 0003205086 scopus 로고
    • Fish and environmental chemicals-a critical evaluation of tests
    • Braunbeck T., Hanke W., and Segner H. (Eds), Wiley-VCH, Weinheim
    • Nagel R. Fish and environmental chemicals-a critical evaluation of tests. In: Braunbeck T., Hanke W., and Segner H. (Eds). Fish Ecotoxicology and Ecophysiology (1993), Wiley-VCH, Weinheim 147-156
    • (1993) Fish Ecotoxicology and Ecophysiology , pp. 147-156
    • Nagel, R.1
  • 72
    • 0037400509 scopus 로고    scopus 로고
    • Effects of phytosterols on zebrafish reproduction in multigeneration test
    • Nakari T., and Erkomaa K. Effects of phytosterols on zebrafish reproduction in multigeneration test. Environ. Pollut. 123 (2003) 267-273
    • (2003) Environ. Pollut. , vol.123 , pp. 267-273
    • Nakari, T.1    Erkomaa, K.2
  • 75
    • 0142106401 scopus 로고    scopus 로고
    • Gonad development and vitellogenin production in zebrafish (Danio rerio) exposed to ethinylestradiol and methyltestosterone
    • Örn S., Holbech H., Madsen T.H., Norrgren L., and Petersen G.I. Gonad development and vitellogenin production in zebrafish (Danio rerio) exposed to ethinylestradiol and methyltestosterone. Aquat. Toxicol. 65 (2003) 397-411
    • (2003) Aquat. Toxicol. , vol.65 , pp. 397-411
    • Örn, S.1    Holbech, H.2    Madsen, T.H.3    Norrgren, L.4    Petersen, G.I.5
  • 76
    • 33745280627 scopus 로고    scopus 로고
    • Comparison of vitellogenin induction, sex ratio, and gonad morphology between zebrafish and Japanese medaka after exposure to 17α-ethinylestradiol and 17β-trenbolone
    • Örn S., Yamani S., and Norrgren L. Comparison of vitellogenin induction, sex ratio, and gonad morphology between zebrafish and Japanese medaka after exposure to 17α-ethinylestradiol and 17β-trenbolone. Arch. Environ. Contam. Toxicol. 51 (2006) 237-243
    • (2006) Arch. Environ. Contam. Toxicol. , vol.51 , pp. 237-243
    • Örn, S.1    Yamani, S.2    Norrgren, L.3
  • 77
    • 41349092257 scopus 로고    scopus 로고
    • Variability in measures of reproductive success in laboratory-kept colonies of zebrafish and implications for studies addressing population-level effects of environmental chemicals
    • Paull G.C., van Look K.J.W., Santos E.M., Filby A.L., Gray D.M., Nash J.P., and Tyler C.R. Variability in measures of reproductive success in laboratory-kept colonies of zebrafish and implications for studies addressing population-level effects of environmental chemicals. Aquat. Toxicol. 87 (2008) 115-126
    • (2008) Aquat. Toxicol. , vol.87 , pp. 115-126
    • Paull, G.C.1    van Look, K.J.W.2    Santos, E.M.3    Filby, A.L.4    Gray, D.M.5    Nash, J.P.6    Tyler, C.R.7
  • 78
    • 0035371622 scopus 로고    scopus 로고
    • Endocrine sex control strategies for the feminization of fish
    • Piferrer F. Endocrine sex control strategies for the feminization of fish. Aquaculture 197 (2001) 229-281
    • (2001) Aquaculture , vol.197 , pp. 229-281
    • Piferrer, F.1
  • 79
    • 4444340536 scopus 로고    scopus 로고
    • Subfunctioning partitioning, the teleost radiation, and the annotation of the human genome
    • Postlethwait J., Amores A., Cresko W., Singer A., and Yan W.L. Subfunctioning partitioning, the teleost radiation, and the annotation of the human genome. Trends Genet. 20 (2004) 481-490
    • (2004) Trends Genet. , vol.20 , pp. 481-490
    • Postlethwait, J.1    Amores, A.2    Cresko, W.3    Singer, A.4    Yan, W.L.5
  • 80
    • 20444387577 scopus 로고    scopus 로고
    • Characterization and expression pattern of zebrafish anti-Müllerian hormone (amh) relative to sox9a, sox9b, and cyp19a1a during gonad development
    • Rodriguez-Mari A., Yan Y.L., BreMiller R.A., Wilson C., Canestro C., and Postlethwait. Characterization and expression pattern of zebrafish anti-Müllerian hormone (amh) relative to sox9a, sox9b, and cyp19a1a during gonad development. Gene Expr. Patterns 5 (2005) 655-667
    • (2005) Gene Expr. Patterns , vol.5 , pp. 655-667
    • Rodriguez-Mari, A.1    Yan, Y.L.2    BreMiller, R.A.3    Wilson, C.4    Canestro, C.5    Postlethwait6
  • 83
    • 0141758386 scopus 로고    scopus 로고
    • Dendritic growth and spine formation in response to estrogen in the developing Purkinje cell
    • Sakamoto H., Mezaki Y., Shikimi H., Ukena K., and Tsuitsui K. Dendritic growth and spine formation in response to estrogen in the developing Purkinje cell. Endorcrinology 144 (2003) 4466-4477
    • (2003) Endorcrinology , vol.144 , pp. 4466-4477
    • Sakamoto, H.1    Mezaki, Y.2    Shikimi, H.3    Ukena, K.4    Tsuitsui, K.5
  • 85
    • 34347393939 scopus 로고    scopus 로고
    • Concentration- and time-dependent effects of the synthetic estrogen, 17α-ethynylestradiol, on reproductive capabilities of the zebrafish, Danio rerio
    • Schäfers C., Teigeler M., Wenzel A., Maack G., Fenske M., and Segner H. Concentration- and time-dependent effects of the synthetic estrogen, 17α-ethynylestradiol, on reproductive capabilities of the zebrafish, Danio rerio. J. Toxicol. Environ. Health, Part A 70 (2007) 768-779
    • (2007) J. Toxicol. Environ. Health, Part A , vol.70 , pp. 768-779
    • Schäfers, C.1    Teigeler, M.2    Wenzel, A.3    Maack, G.4    Fenske, M.5    Segner, H.6
  • 86
    • 34548565847 scopus 로고    scopus 로고
    • Estrogen-induced alterations in amh and dmrt1 expression signal for disruption in male sexual development in the zebrafish
    • Schulz R.W., Bogerd J., Male R., Ball J., Fenske M., Olsen L.C., and Tyler C.R. Estrogen-induced alterations in amh and dmrt1 expression signal for disruption in male sexual development in the zebrafish. Environ. Sci. Technol. 41 (2007) 6305-6310
    • (2007) Environ. Sci. Technol. , vol.41 , pp. 6305-6310
    • Schulz, R.W.1    Bogerd, J.2    Male, R.3    Ball, J.4    Fenske, M.5    Olsen, L.C.6    Tyler, C.R.7
  • 88
    • 0037338715 scopus 로고    scopus 로고
    • Potencies of estrogenic compounds in in vitro screening assays and in life cycle tests with zebrafish in vivo
    • Segner H., Navas J.M., Schäfers C., and Wenzel A. Potencies of estrogenic compounds in in vitro screening assays and in life cycle tests with zebrafish in vivo. Ecotoxicol. Environ. Saf. 54 (2003) 315-322
    • (2003) Ecotoxicol. Environ. Saf. , vol.54 , pp. 315-322
    • Segner, H.1    Navas, J.M.2    Schäfers, C.3    Wenzel, A.4
  • 89
    • 34548447813 scopus 로고    scopus 로고
    • The impact of environmental hormonally active substances on the endocrine and immune systems of fish
    • Reinecke M., Zaccone G., and Kapoor B.G. (Eds), Science Publishers, Enfield (NH)
    • Segner H., Eppler E., and Reinecke M. The impact of environmental hormonally active substances on the endocrine and immune systems of fish. In: Reinecke M., Zaccone G., and Kapoor B.G. (Eds). Fish Endocrinology (2006), Science Publishers, Enfield (NH) 809-865
    • (2006) Fish Endocrinology , pp. 809-865
    • Segner, H.1    Eppler, E.2    Reinecke, M.3
  • 90
    • 44649122644 scopus 로고    scopus 로고
    • Developmental toxicity and alteration of gene expression in zebrafish embryos exposed to PFOS
    • Shi X., Du Y., Lam P.K.S., Wu R.S.S., and Zhou B. Developmental toxicity and alteration of gene expression in zebrafish embryos exposed to PFOS. Toxicol. Appl. Pharmacol. 230 (2008) 23-32
    • (2008) Toxicol. Appl. Pharmacol. , vol.230 , pp. 23-32
    • Shi, X.1    Du, Y.2    Lam, P.K.S.3    Wu, R.S.S.4    Zhou, B.5
  • 91
    • 38349002576 scopus 로고    scopus 로고
    • The behaviour and ecology of the zebrafish, Danio rerio
    • Spence R., Gerlach G., Lawrence C., and Smith C. The behaviour and ecology of the zebrafish, Danio rerio. Biol. Rev. 83 (2008) 13-34
    • (2008) Biol. Rev. , vol.83 , pp. 13-34
    • Spence, R.1    Gerlach, G.2    Lawrence, C.3    Smith, C.4
  • 92
    • 0037257973 scopus 로고    scopus 로고
    • The state of the art of the zebrafish model for toxicology and toxicopathology research-advantages and current limitations
    • (suppl)
    • Spitsbergen J.M., and Kent M.L. The state of the art of the zebrafish model for toxicology and toxicopathology research-advantages and current limitations. Toxicol. Pathol. 31 (2003) 62-87 (suppl)
    • (2003) Toxicol. Pathol. , vol.31 , pp. 62-87
    • Spitsbergen, J.M.1    Kent, M.L.2
  • 93
    • 44949178689 scopus 로고    scopus 로고
    • Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain
    • Sreenivasan R., Cai M., Bartfai R., Wang X., Christoffels A., and Orban L. Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain. PloS One 3 (2008) e1791
    • (2008) PloS One , vol.3
    • Sreenivasan, R.1    Cai, M.2    Bartfai, R.3    Wang, X.4    Christoffels, A.5    Orban, L.6
  • 94
    • 20744448987 scopus 로고    scopus 로고
    • Lessons from endocrine disruption and their application to other issues concerning trace organics in the aquatic environment
    • Sumpter J.P., and Johnson A.J. Lessons from endocrine disruption and their application to other issues concerning trace organics in the aquatic environment. Environ. Sci. Technol. 39 (2005) 4321-4332
    • (2005) Environ. Sci. Technol. , vol.39 , pp. 4321-4332
    • Sumpter, J.P.1    Johnson, A.J.2
  • 95
    • 0002901424 scopus 로고
    • Juvenile hermaphroditism in the zebrafish, Brachydanio rerio
    • Takahashi H. Juvenile hermaphroditism in the zebrafish, Brachydanio rerio. Bull. Fac. Fish. Hokkaido Univ. 28 (1977) 57-65
    • (1977) Bull. Fac. Fish. Hokkaido Univ. , vol.28 , pp. 57-65
    • Takahashi, H.1
  • 96
    • 35448957749 scopus 로고    scopus 로고
    • Associations between altered vitellogenin concentrations and adverse health effects in fathead minnow
    • Thorpe K.L., Benstaedt R., Hutchinson T.H., and Tyler C.R. Associations between altered vitellogenin concentrations and adverse health effects in fathead minnow. Aquat. Toxicol. 85 (2007) 176-183
    • (2007) Aquat. Toxicol. , vol.85 , pp. 176-183
    • Thorpe, K.L.1    Benstaedt, R.2    Hutchinson, T.H.3    Tyler, C.R.4
  • 97
    • 3342981522 scopus 로고    scopus 로고
    • Expression patterns of three estrogen receptor genes during zebrafish (Danio rerio) development: evidence for high expression in neuromasts
    • Tingaud-Sequeira A., Andre M., Forgue J., Barthe C., and Babin P.J. Expression patterns of three estrogen receptor genes during zebrafish (Danio rerio) development: evidence for high expression in neuromasts. Gene Expr. Patterns 4 (2004) 561-568
    • (2004) Gene Expr. Patterns , vol.4 , pp. 561-568
    • Tingaud-Sequeira, A.1    Andre, M.2    Forgue, J.3    Barthe, C.4    Babin, P.J.5
  • 98
    • 0035883938 scopus 로고    scopus 로고
    • Developmental expression of cytochrome P450 aromatase genes (CYP19a and CYP19b) in zebrafish fry (Danio rerio)
    • Trant J.M., Gavasso S., Ackers J., Chung B.C., and Place A.R. Developmental expression of cytochrome P450 aromatase genes (CYP19a and CYP19b) in zebrafish fry (Danio rerio). J. Exp. Zool. 290 (2001) 475-483
    • (2001) J. Exp. Zool. , vol.290 , pp. 475-483
    • Trant, J.M.1    Gavasso, S.2    Ackers, J.3    Chung, B.C.4    Place, A.R.5
  • 99
    • 0031844641 scopus 로고    scopus 로고
    • Endocrine disruption in wildlife: a critical review of the evidence
    • Tyler C.R., Jobling S., and Sumpter J.P. Endocrine disruption in wildlife: a critical review of the evidence. Crit. Rev. Toxicol. 28 (1998) 319-361
    • (1998) Crit. Rev. Toxicol. , vol.28 , pp. 319-361
    • Tyler, C.R.1    Jobling, S.2    Sumpter, J.P.3
  • 100
    • 0036910293 scopus 로고    scopus 로고
    • Window of sensitivity for the estrogenic effects of ethynylestradiol in early life stages of fathead minnow, Pimephales promelas
    • Van Aerle R., Pounds N., Hutchinson T.R., Maddix S., and Tyler C.R. Window of sensitivity for the estrogenic effects of ethynylestradiol in early life stages of fathead minnow, Pimephales promelas. Ecotoxicology 11 (2002) 423-434
    • (2002) Ecotoxicology , vol.11 , pp. 423-434
    • Van Aerle, R.1    Pounds, N.2    Hutchinson, T.R.3    Maddix, S.4    Tyler, C.R.5
  • 101
    • 0034749524 scopus 로고    scopus 로고
    • Reproductive effects of ethynylestradiol and 4t-octylphenol on the zebrafish (Danio rerio)
    • van den Belt K., Verheyen R., and Witters H. Reproductive effects of ethynylestradiol and 4t-octylphenol on the zebrafish (Danio rerio). Arch. Environ. Contam. Toxicol. 41 (2001) 458-467
    • (2001) Arch. Environ. Contam. Toxicol. , vol.41 , pp. 458-467
    • van den Belt, K.1    Verheyen, R.2    Witters, H.3
  • 102
    • 0037906145 scopus 로고    scopus 로고
    • Histopathology as a tool for the evaluation of endocrine disruption in zebrafish (Danio rerio)
    • van der Ven L.T.M., Wester P.W., and Vos J.G. Histopathology as a tool for the evaluation of endocrine disruption in zebrafish (Danio rerio). Environ. Toxicol. Chem. 22 (2003) 908-913
    • (2003) Environ. Toxicol. Chem. , vol.22 , pp. 908-913
    • van der Ven, L.T.M.1    Wester, P.W.2    Vos, J.G.3
  • 103
    • 33846569525 scopus 로고    scopus 로고
    • Effects of the estrogen agonist 17β-estradiol and antagonist tamoxifen in a partial life cycle assay with zebrafish
    • van der Ven L.T.M., van den Brandhof E.J., Vos J.H., and Wester P.W. Effects of the estrogen agonist 17β-estradiol and antagonist tamoxifen in a partial life cycle assay with zebrafish. Environ. Toxicol. Chem. 26 (2006) 92-99
    • (2006) Environ. Toxicol. Chem. , vol.26 , pp. 92-99
    • van der Ven, L.T.M.1    van den Brandhof, E.J.2    Vos, J.H.3    Wester, P.W.4
  • 104
    • 34548076070 scopus 로고    scopus 로고
    • Characterization of early molecular sex differentiation in rainbow trout, Oncorhynchus mykiss
    • Vizziano D., Randunieau G., Baron D., Cauty C., and Guiguen Y. Characterization of early molecular sex differentiation in rainbow trout, Oncorhynchus mykiss. Dev. Dyn. 236 (2007) 2198-2206
    • (2007) Dev. Dyn. , vol.236 , pp. 2198-2206
    • Vizziano, D.1    Randunieau, G.2    Baron, D.3    Cauty, C.4    Guiguen, Y.5
  • 105
    • 31144462633 scopus 로고    scopus 로고
    • Dynamic gene expression changes precede dioxin-induced liver pathogenesis in medaka fish
    • Volz D.C., Hinton D.E., McHugh Law J., and Kullman S.W. Dynamic gene expression changes precede dioxin-induced liver pathogenesis in medaka fish. Toxicol. Sci. 89 (2006) 524-534
    • (2006) Toxicol. Sci. , vol.89 , pp. 524-534
    • Volz, D.C.1    Hinton, D.E.2    McHugh Law, J.3    Kullman, S.W.4
  • 106
    • 27944438485 scopus 로고    scopus 로고
    • Zebrafish sex determination and differentiation: involvement of FTZ-F1 genes
    • von Hofsten J., and Olsson P.E. Zebrafish sex determination and differentiation: involvement of FTZ-F1 genes. Reprod. Biol. Endocrinol. 3 (2005) 63
    • (2005) Reprod. Biol. Endocrinol. , vol.3 , pp. 63
    • von Hofsten, J.1    Olsson, P.E.2
  • 109
    • 4544328469 scopus 로고    scopus 로고
    • Qualitative and quantitative assessment of fathead minnow Pimephales promelas gonads as an endpoint for evaluating endocrine-active compounds: a pilot methodology study
    • Wolf J.C., Dietrich D.R., Friederich U., Caunter J., and Brown A.R. Qualitative and quantitative assessment of fathead minnow Pimephales promelas gonads as an endpoint for evaluating endocrine-active compounds: a pilot methodology study. Toxicol. Pathol. 32 (2004) 600-612
    • (2004) Toxicol. Pathol. , vol.32 , pp. 600-612
    • Wolf, J.C.1    Dietrich, D.R.2    Friederich, U.3    Caunter, J.4    Brown, A.R.5
  • 110
    • 43149104589 scopus 로고    scopus 로고
    • Exposure to 17α-ethynylestradiol impairs reproductive functions of both male and female zebrafish
    • Xu H., Yang J., Wang J., Jiang Q., Chen H., and Song H. Exposure to 17α-ethynylestradiol impairs reproductive functions of both male and female zebrafish. Aquat. Toxicol. 88 (2008) 1-8
    • (2008) Aquat. Toxicol. , vol.88 , pp. 1-8
    • Xu, H.1    Yang, J.2    Wang, J.3    Jiang, Q.4    Chen, H.5    Song, H.6
  • 112
    • 3142680853 scopus 로고    scopus 로고
    • Physiology. Heeding the hormonal call
    • Zakon H. Physiology. Heeding the hormonal call. Science 305 (2004) 349-350
    • (2004) Science , vol.305 , pp. 349-350
    • Zakon, H.1
  • 113
    • 12144273121 scopus 로고    scopus 로고
    • In vivo drug discovery in the zebrafish
    • Zon L.I., and Peterson R.T. In vivo drug discovery in the zebrafish. Nat. Rev. Drug Discov. 4 (2005) 35-44
    • (2005) Nat. Rev. Drug Discov. , vol.4 , pp. 35-44
    • Zon, L.I.1    Peterson, R.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.