Regulation of ZIP and ZnT zinc transporters in zebrafish gill: Zinc repression of ZIP10 transcription by an intronic MRE cluster

Physiological Genomics

Volumn 34, Issue 2, 2008, Pages 205-214

  Zheng, Dongling ^a,c   Feeney, Graham P ^b   Kille, Peter ^b   Hogstrand, Christer ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Metal regulatory transcription factor 1; Metal response element; Metallothionein; SLC30; SLC39; Transcriptional regulation

Indexed keywords

DNA FRAGMENT; MESSENGER RNA; METALLOTHIONEIN II; PROTEIN ZIP10; PROTEIN ZIP3; PROTEIN ZNT1; PROTEIN ZNT5; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MTF1; UNCLASSIFIED DRUG; ZINC TRANSPORTER; CARRIER PROTEIN; LUCIFERASE; METALLOTHIONEIN; ZEBRAFISH PROTEIN; ZINC; ZINC BINDING PROTEIN; ZINC-BINDING PROTEIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME REGULATION; GENE DELETION; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION SITE; ZEBRA FISH; ZINC DEFICIENCY; 5' UNTRANSLATED REGION; ANIMAL; DNA RESPONSIVE ELEMENT; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; GILL; INTRON; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SEQUENCE ALIGNMENT;

DANIO RERIO;

5' UNTRANSLATED REGIONS; ANIMALS; BASE SEQUENCE; CARRIER PROTEINS; GENE EXPRESSION REGULATION; GILLS; INTRONS; LUCIFERASES; METALLOTHIONEIN; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RESPONSE ELEMENTS; RNA, MESSENGER; SEQUENCE ALIGNMENT; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC; ZEBRAFISH; ZEBRAFISH PROTEINS; ZINC;

EID: 49049109504     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.90206.2008     Document Type: Article

References (49)

1. Balesaria S, Hogstrand C. Identification, cloning and characterization of a plasma membrane zinc efflux transporter, TrZnT-1, from fugu pufferfish (Takifugu rubripes). Biochem J 394: 485-493, 2006.
2. Beyersmann D, Haase H. Functions of zinc in signaling, proliferation and differentiation of mammalian cells. Biometals 14: 331-341, 2001.
3. Chen WY, John JA, Lin CH, Lin HF, Wu SC, Lin CH, Chang CY. Expression of metallothionein gene during embryonic and early larval development in zebrafish. Aquat Toxicol 69: 215-227, 2004.
4. Chimienti F, Aouffen M, Favier A, Seve M. Zinc homeostasis-regulating proteins: new drug targets for triggering cell fate. Curr Drug Targets 4: 323-338, 2003.
5. Coleman JE. Zinc proteins: enzymes, storage proteins, transcription factors, and replication proteins. Annu Rev Biochem 61: 897-946, 1992.
6. Cousins RJ, Blanchard RK, Popp MP, Liu L, Cao J, Moore JB, Green CL. A global view of the selectivity of zinc deprivation and excess on genes expressed in human THP-1 mononuclear cells. Proc Natl Acad Sci USA 100: 6952-6957, 2003.
7. Cousins RJ, Liuzzi JP, Lichten LA. Mammalian zinc transport, trafficking, and signals. J Biol Chem 281: 24085-24089, 2006.
8. Cragg RA, Christie GR, Phillips SR, Russi RM, Kury S, Mathers JC, Taylor PM, Ford D. A novel zinc-regulated human zinc transporter, hZTL1, is localized to the enterocyte apical membrane. J Biol Chem 277: 22789-22797, 2002.
9. Cragg RA, Phillips SR, Piper JM, Varma JS, Campbell FC, Mathers JC, Ford D. Homeostatic regulation of zinc transporters in the human small intestine by dietary zinc supplementation. Gut 54: 469-478, 2005.
10. Devergnas S, Chimienti F, Naud N, Pennequin A, Coquerel Y, Chantegrel J, Favier A, Seve M. Differential regulation of zinc efflux transporters ZnT-1, ZnT-5 and ZnT-7 gene expression by zinc levels: a real-time RT-PCR study. Biochem Pharmacol 68: 699-709, 2004.
11. Dufner-Beattie J, Langmade SJ, Wang F, Eide D, Andrews GK. Structure, function, and regulation of a subfamily of mouse zinc transporter genes. J Biol Chem 278: 50142-50150, 2003.
12. Dufner-Beattie J, Wang F, Kuo YM, Gitschier J, Eide D, Andrews GK. The acrodermatitis enteropathica gene ZIP4 encodes a tissue-specific, zinc-regulated zinc transporter in mice. J Biol Chem 278: 33474-33481, 2003.
13. Feeney GP, Zheng D, Kille P, Hogstrand C. The phylogeny of teleost ZIP and ZnT zinc transporters and their tissue specific expression and response to zinc in zebrafish. Biochim Biophys Acta 1732: 88-95, 2005.
14. Fosmire GJ. Zinc toxicity. Am J Clin Nutr 51: 225-227, 1990.
15. Fraker PJ, King LE, Laakko T, Vollmer TL. The dynamic link between the integrity of the immune system and zinc status. J Nutr 130: 1399S-1406S, 2000.
16. Hambidge M. Human zinc deficiency. J Nutr 130: 1344S-1349S, 2000.
17. Hamer DH. Metallothionein. Annu Rev Biochem 55: 913-951, 1986.
18. Heuchel R, Radtke F, Georgiev O, Stark G, Aguet M, Schaffner W. The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression. EMBO J 13: 2870-2875, 1994.
19. Hijova E. Metallothioneins and zinc: their functions and interactions. Bratisl Lek Listy 105: 230-234, 2004.
20. 2+. J Exp Biol 198: 337-348, 1995.
21. Hogstrand C, Webb N, Wood CM. Covariation in regulation of affinity for branchial zinc and calcium uptake in freshwater rainbow trout. J Exp Biol 201: 1809-1815, 1998.
22. Ishihara K, Yamazaki T, Ishida Y, Suzuki T, Oda K, Nagao M, Yamaguchi-Iwai Y, Kambe T. Zinc transport complexes contribute to the homeostatic maintenance of secretory pathway function in vertebrate cells. J Biol Chem 281: 17743-17750, 2006.
23. Jackson KA, Helston RM, McKay JA, O'Neill ED, Mathers JC, Ford D. Splice variants of the human zinc transporter ZnT5 (SLC30A5) are differentially localised and regulated by zinc through transcription and mRNA stability. J Biol Chem 282: 10423-10431, 2007.
24. Kagara N, Tanaka N, Noguchi S, Hirano T. Zinc and its transporter ZIP10 are involved in invasive behavior of breast cancer cells. Cancer Sci 98: 692-697, 2007.
25. Kaler P, Prasad R. Molecular cloning and functional characterization of novel zinc transporter rZip10 (Slc39a10) involved in zinc uptake across rat renal brush-border membrane. Am J Physiol Renal Physiol 292: F217-F229, 2007.
26. Kambe T, Narita H, Yamaguchi-Iwai Y, Hirose J, Amano T, Sugiura N, Sasaki R, Mori K, Iwanaga T, Nagao M. Cloning and characterization of a novel mammalian zinc transporter, zinc transporter 5, abundantly expressed in pancreatic beta cells. J Biol Chem 277: 19049-19055, 2002.
27. Kelleher SL, Lonnerdal B. Zinc transporters in the rat mammary gland respond to marginal zinc and vitamin A intakes during lactation. J Nutr 132: 3280-3285, 2002.
28. Koizumi S, Suzuki K, Ogra Y, Yamada H, Otsuka F. Transcriptional activity and regulatory protein binding of metal-responsive elements of the human metallothionein-IIA gene. Eur J Biochem 259: 635-642, 1999.
29. Langmade SJ, Ravindra R, Daniels PJ, Andrews GK. The transcription factor MTF-1 mediates metal regulation of the mouse ZnT1 gene. J Biol Chem 275: 34803-34809, 2000.
30. Liuzzi JP, Blanchard RK, Cousins RJ. Differential regulation of zinc transporter 1, 2, and 4 mRNA expression by dietary zinc in rats. J Nutr 131: 46-52, 2001.
31. Liuzzi JP, Cousins RJ. Mammalian zinc transporters. Annu Rev Nutr 24: 151-172, 2004.
32. Mao X, Kim BE, Wang F, Eide DJ, Petris MJ. A histidine-rich cluster mediates the ubiquitination and degradation of the human zinc transporter, hZIP4, and protects against zinc cytotoxicity. J Biol Chem 282: 6992-7000, 2007.
33. McMahon RJ, Cousins RJ. Regulation of the zinc transporter ZnT-1 by dietary zinc. Proc Natl Acad Sci USA 95: 4841-4846, 1998.
34. Muylle F, Robbens J, De CW, Timmermans JP, Blust R. Cadmium and zinc induction of ZnT-1 mRNA in an established carp cell line. Comp Biochem Physiol C Toxicol Pharmacol 143: 242-251, 2006.
35. Olsson PE, Kille P. Functional comparison of the metal-regulated transcriptional control regions of metallothionein genes from cadmium-sensitive and tolerant fish species. Biochim Biophys Acta 1350: 325-334, 1997.
36. Palmiter RD. Protection against zinc toxicity by metallothionein and zinc transporter 1. Proc Natl Acad Sci USA 101: 4918-4923, 2004.
37. Palmiter RD, Findley SD. Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc. EMBO J 14: 639-649, 1995.
38. Prasad AS. Recognition of zinc-deficiency syndrome. Nutrition 17: 67-69, 2001.
39. Qiu A, Hogstrand C. Functional characterisation and genomic analysis of an epithelial calcium channel (ECaC) from pufferfish, Fugu rubripes. Gene 342: 113-123, 2004.
40. Qiu A, Hogstrand C. Functional expression of a low-affinity zinc uptake transporter (FrZIP2) from pufferfish (Takifugu rubripes) in MDCK cells. Biochem J 390: 777-786, 2005.
41. Qiu A, Shayeghi M, Hogstrand C. Molecular cloning and functional characterization of a high-affinity zinc importer (DrZIP1) from zebrafish (Danio rerio). Biochem J 388: 745-754, 2005.
42. Suh SW, Chen JW, Motamedi M, Bell B, Listiak K, Pons NF, Danscher G, Frederickson CJ. Evidence that synaptically-released zinc contributes to neuronal injury after traumatic brain injury. Brain Res 852: 268-273, 2000.
43. Suzuki T, Ishihara K, Migaki H, Ishihara K, Nagao M, Yamaguchi-Iwai Y, Kambe T. Two different zinc transport complexes of cation diffusion facilitator proteins localized in the secretory pathway operate to activate alkaline phosphatases in vertebrate cells. J Biol Chem 280: 30956-30962, 2005.
44. Umenishi F, Verkman AS. Isolation and functional analysis of alternative promoters in the human aquaporin-4 water channel gene. Genomics 50: 373-377, 1998.
45. Weaver BP, Dufner-Beattie J, Kambe T, Andrews GK. Novel zincresponsive post-transcriptional mechanisms reciprocally regulate expression of the mouse Slc39a4 and Slc39a5 zinc transporters (Zip4 and Zip5). Biol Chem 388: 1301-1312, 2007.
46. Wimmer U, Wang Y, Georgiev O, Schaffner W. Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione. Nucleic Acids Res 33: 5715-5727, 2005.
47. Zhao H, Butler E, Rodgers J, Spizzo T, Duesterhoeft S, Eide D. Regulation of zinc homeostasis in yeast by binding of the ZAP1 transcriptional activator to zinc-responsive promoter elements. J Biol Chem 273: 28713-28720, 1998.
48. Zhao H, Eide D. The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation. Proc Natl Acad Sci USA 93: 2454-2458, 1996.
49. Zhao H, Eide D. The ZRT2 gene encodes the low affinity zinc transporter in Saccharomyces cerevisiae. J Biol Chem 271: 23203-23210, 1996.