Microarray analysis in the zebrafish (Danio rerio) liver and telencephalon after exposure to low concentration of 17alpha-ethinylestradiol

Aquatic Toxicology

Volumn 84, Issue 1, 2007, Pages 38-49

  Martyniuk, Christopher J ^a   Gerrie, Emily R ^a   Popesku, Jason T ^a   Ekker, Marc ^a   Trudeau, Vance L ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

17Alpha ethinylestradiol; GO terms; Oligonucleotide; Telencephalon; Vitellogenin; Zebrafish

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); APOLIPOPROTEIN A1; BIOLOGICAL MARKER; ESTROGEN RECEPTOR ALPHA; ETHINYLESTRADIOL; MESSENGER RNA; OLIGONUCLEOTIDE; UNCLASSIFIED DRUG; VITELLOGENIN; VITELLOGENIN 1; VITELLOGENIN 3;

AQUATIC ORGANISM; BIOMARKER; BRAIN; CYPRINID; ENDOCRINE DISRUPTOR; ENZYME ACTIVITY; ESTROGENIC COMPOUND; METABOLISM; POLLUTION EFFECT; POLLUTION EXPOSURE; POLYMERASE CHAIN REACTION; PROTEIN; RNA; SEWAGE DISPOSAL; STEROID;

ANIMAL TISSUE; ARTICLE; BRAIN TOXICITY; CARBOHYDRATE METABOLISM; CELL COMMUNICATION; CONCENTRATION RESPONSE; DOWN REGULATION; ELECTRON TRANSPORT; ENVIRONMENTAL EXPOSURE; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENETIC ANALYSIS; LIVER TOXICITY; MALE; MICROARRAY ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; REPRODUCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEWAGE EFFLUENT; TELENCEPHALON; TISSUE SPECIFICITY; ZEBRA FISH;

ANIMALS; APOLIPOPROTEIN A-I; ESTROGEN RECEPTOR ALPHA; ETHINYL ESTRADIOL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; LIVER; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SODIUM-POTASSIUM-EXCHANGING ATPASE; TELENCEPHALON; VITELLOGENINS; WATER POLLUTANTS, CHEMICAL; ZEBRAFISH;

DANIO RERIO;

EID: 34547104388     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2007.05.012     Document Type: Article

References (47)

1. Akbas G.E., Song J., and Taylor H.S. A HOXA10 estrogen response element (ERE) is differentially regulated by 17 beta-estradiol and diethylstilbestrol (DES). J. Mol. Biol. 340 5 (2004) 1013-1023
2. Andreassen T.K., Skjoedt K., and Korsgaard B. Upregulation of estrogen receptor alpha and vitellogenin in eelpout (Zoarces viviparus) by waterborne exposure to 4-tert-octylphenol and 17beta-estradiol. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 140 (2005) 340-346
3. Ashburner M., Ball C.A., Blake J.A., Botstein D., Butler H., Cherry J.M., Davis A.P., Dolinski K., Dwight S.S., Eppig J.T., Harris M.A., Hill D.P., Issel-Tarver L., Kasarskis A., Lewis S., Matese J.C., Richardson J.E., Ringwald M., Rubin G.M., and Sherlock G. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat. Genet. 25 1 (2000) 25-29
4. Balch G.C., Mackenzie C.A., and Metcalfe C.D. Alterations to gonadal development and reproductive success in Japanese medaka (Oryzias latipes) exposed to 17alpha-ethinylestradiol. Environ. Toxicol. Chem. 23 (2004) 782-791
5. Brian J.V., Harris C.A., Scholze M., Backhaus T., Booy P., Lamoree M., Pojana G., Jonkers N., Runnalls T., Bonfa A., Marcomini A., and Sumpter J.P. Accurate prediction of the response of freshwater fish to a mixture of estrogenic chemicals. Environ. Health Perspect. 113 6 (2005) 721-728
6. Callard G.V., Tchoudakova A.V., Kishida M., and Wood E. Differential tissue distribution, developmental programming, estrogen regulation and promoter characteristics of cyp19 genes in teleost fish. J. Steroid Biochem. Mol. Biol. 79 1-5 (2001) 305-314
7. Daftary G.S., and Taylor H.S. Endocrine regulation of HOX genes. Endocr. Rev. 27 4 (2006) 331-355
8. Fei X., Chung H., and Taylor H.S. Methoxychlor disrupts uterine Hoxa10 gene expression. Endocrinology 146 (2005) 3445-3451
9. Flouriot G., Pakdel F., and Valotaire Y. Transcriptional and post-transcriptional regulation of rainbow trout estrogen receptor and vitellogenin gene expression. Mol. Cell. Endocrinol. 124 (1996) 173-181
10. Fraysse B., Mons R., and Garric J. Development of a zebrafish 4-day embryo-larval bioassay to assess toxicity of chemicals. Ecotoxicol. Environ. Saf. 63 (2006) 253-267
11. Gracey A.Y., Fraser E.J., Li W., Fang Y., Taylor R.R., Rogers J., Brass A., and Cossins A.R. Coping with cold: an integrative, multitissue analysis of the transcriptome of a poikilothermic vertebrate. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 16970-16975
12. Heneweer M., Muusse M., van den Berg M., and Sanderson J.T. Additive estrogenic effects of mixtures of frequently used UV filters on pS2-gene transcription in MCF-7 cells. Toxicol. Appl. Pharmacol. 208 (2005) 170-177
13. Hett A.K., and Ludwig A. SRY-related (SOX) genes in the genome of European Atlantic sturgeon (Acipenser sturio). Genome 48 (2005) 181-186
14. Hoffmann J.L., Torontali S.P., Thomason R.G., Lee D.M., Brill J.L., Price B.B., Carr G.J., and Versteeg D.J. Hepatic gene expression profiling using Genechips in zebrafish exposed to 17alpha-ethinylestradiol. Aquat. Toxicol. 79 (2006) 233-246
15. Islinger M., Willimski D., Volkl A., and Braunbeck T. Effects of 17α-ethinylestradiol on the expression of three estrogen-responsive genes and cellular ultrastructure of liver and testes in male zebrafish. Aquat. Toxicol. 62 2 (2003) 85-103
16. Kimmel C.B., Ballard W.W., Kimmel S.R., Ullmann B., and Schilling T.F. Stages of embryonic development of the zebrafish. Dev. Dyn. 203 (1995) 253-310
17. Kolpin D.W., Furlong E.T., Meyer M.T., Thurman E.M., Zaugg S.D., Barber L.B., and Buxton H.T. Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams 1999-2000: a national reconnaissance. Environ. Sci. Technol. 36 (2002) 1202-1211
18. Koopman P., Schepers G., Brenner S., and Venkatesh B. Origin and diversity of the SOX transcription factor gene family: genome-wide analysis in Fugu rubripes. Gene 328 (2004) 177-186
19. Lee K.H., Finnigan-Bunick C., Bahr J., and Bunick D. Estrogen regulation of ion transporter messenger RNA levels in mouse efferent ductules are mediated differentially through estrogen receptor (ER) alpha and ER beta. Biol. Reprod. 65 (2001) 1534-1541
20. Martyniuk C.J., Xiong H., Crump K., Chiu S., Sardana R., Nadler A., Gerrie E.R., Xia X., and Trudeau V.L. Gene expression profiling in the neuroendocrine brain of male goldfish (Carassius auratus) exposed to 17alpha-ethinylestradiol. Physiol. Genom. 27 3 (2006) 328-336
21. Marvanova M., Lakso M., and Wong G. Identification of genes regulated by memantine and MK-801 in adult rat brain by cDNA microarray analysis. Neuropsychopharmacology 29 (2004) 1070-1079
22. Miccio M., Orzes N., Lunazzi G.C., Gazzin B., Corsi R., and Tiribelli C. Reversal of ethinylestradiol-induced cholestasis by epomediol in rat. The role of liver plasma-membrane fluidity. Biochem. Pharmacol. 38 20 (1989) 3559-3563
23. Miracle A., Ankley G., and Lattier D. Expression of two vitellogenin genes (vg1 and [3vg]) in fathead minnow (Pimephales promelas) liver in response to exposure to steroidal estrogens and androgens. Ecotoxicol. Environ. Saf. 63 3 (2006) 337-342
24. Nash J.P., Kime D.E., Van der Ven L.T., Wester P.W., Brion F., Maack G., Stahlschmidt-Allner P., and Tyler C.R. Long-term exposure to environmental concentrations of the pharmaceutical ethinylestradiol causes reproductive failure in fish. Environ. Health Perspect. 112 17 (2004) 1725-1733
25. Ortiz-Zarragoitia M., and Cajaraville M.P. Effects of selected xenoestrogens on liver peroxisomes, vitellogenin levels and spermatogenic cell proliferation in male zebrafish. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 141 (2005) 133-144
26. Pakdel F., Feon S., Le Gac F., Le Menn F., and Valotaire Y. In vivo estrogen induction of hepatic estrogen receptor mRNA and correlation with vitellogenin mRNA in rainbow trout. Mol. Cell. Endocrinol. 75 3 (1991) 205-212
27. Parrott J.L., and Blunt B.R. Life-cycle exposure of fathead minnows (Pimephales promelas) to an ethinylestradiol concentration below 1 ng/L reduces egg fertilization success and demasculinizes males. Environ. Toxicol. 20 (2005) 131-141
28. Pinto P.I., Teodosio H.R., Galay-Burgos M., Power D.M., Sweeney G.E., and Canario A.V. Identification of estrogen-responsive genes in the testis of sea bream (Sparus auratus) using suppression subtractive hybridization. Mol. Reprod. Dev. 73 3 (2006) 318-329
29. Robinson C.D., Brown E., Craft J.A., Davies I.M., Moffat C.F., Pirie D., Robertson F., Stagg R.M., and Struthers S. Effects of sewage effluent and ethinyl oestradiol upon molecular markers of oestrogenic exposure, maturation and reproductive success in the sand goby (Pomatoschistus minutes Pallas). Aquat. Toxicol. 62 (2003) 119-134
30. Sabo-Attwood T., Kroll K.J., and Denslow N.D. Differential expression of largemouth bass (Micropterus salmoides) estrogen receptor isotypes alpha, beta, and gamma by estradiol. Mol. Cell. Endocrinol. 218 (2004) 107-118
31. Simon F.R., Fortune J., Iwahashi M., Gartung C., Wolkoff A., and Sutherland E. Ethinylestradiol cholestasis involves alterations in expression of liver sinusoidal transporters. Am. J. Physiol. 271 (1996) G1043-G1052
32. Sumpter J.P., and Jobling S. Vitellogenesis as a biomarker for estrogenic contamination of the aquatic environment. Environ. Health Perspect. 103 (1995) 173-178
33. Taylor H.S., Arici A., Olive D., and Igarashi P. HOXA10 is expressed in response to sex steroids at the time of implantation in the human endometrium. J. Clin. Invest. 101 7 (1998) 1379-1384
34. Tchoudakova A., Kishida M., Wood E., and Callard G.V. Promoter characteristics of two cyp19 genes differentially expressed in the brain and ovary of teleost fish. J. Steroid Biochem. Mol. Biol. 78 5 (2001) 427-439
35. Ternes T.A., Stumpf M., Mueller J., Haberer K., Wilken R.D., and Servos M. Behavior and occurrence of estrogens in municipal sewage treatment plants. I. Investigations in Germany, Canada and Brazil. Sci. Total Environ. 225 1-2 (1999) 81-90
36. Thibaut R., Debrauwer L., Perdu E., Goksoyr A., Cravedi J.P., and Arukwe A. Regio-specific hydroxylation of nonylphenol and the involvement of CYP2K- and CYP2M-like iso-enzymes in Atlantic salmon (Salmo salar). Aquat. Toxicol. 56 (2002) 177-190
37. Trudeau V.L., Turque N., Le Mevel S., Alliot C., Gallant N., Coen L., Pakdel F., and Demeneix B. Assessment of estrogenic endocrine-disrupting chemical actions in the brain using in vivo somatic gene transfer. Environ. Health Perspect. 113 3 (2005) 329-334
38. Tong S.K., and Chung B.C. Analysis of zebrafish cyp19 promoters. J. Steroid Biochem. Mol. Biol. 86 (2003) 381-386
39. Van den Belt K., Verheyen R., and Witters H. Reproductive effects of ethinylestradiol and 4t-octylphenol on the zebrafish (Danio rerio). Arch. Environ. Contam. Toxicol. 41 (2001) 458-467
40. van der Ven K., De Wit M., Keil D., Moens L., Van Leemput K., Naudts B., and De Coen W. Development and application of a brain-specific cDNA microarray for effect evaluation of neuro-active pharmaceuticals in zebrafish (Danio rerio). Comp. Biochem. Physiol. B Biochem. Mol. Biol. 141 (2005) 408-417
41. van der Ven K., Keil D., Moens L.N., Van Leemput K., van Remortel P., and De Coen W.M. Neuropharmaceuticals in the environment: mianserin-induced neuroendocrine disruption in zebrafish (Danio rerio) using cDNA microarrays. Environ. Toxicol. Chem. 25 (2006) 2645-2652
42. Versonnen B.J., and Janssen C.R. Xenoestrogenic effects of ethinylestradiol in zebrafish (Danio rerio). Environ. Toxicol. 19 (2004) 198-206
43. Wang H., Tan J.T., Emelyanov A., Korzh V., and Gong Z. Hepatic and extrahepatic expression of vitellogenin genes in the zebrafish, Danio rerio. Gene 356 (2005) 91-100
44. Westerfield M. The Zebrafish Book (1994), Univeristy of Oregan Press, Eugene, OR
45. Wibbels T., Cowan J., and LeBoeuf R. Temperature-dependent sex determination in the red-eared slider turtle, Trachemys scripta. J. Exp. Zool. 281 (1998) 409-416
46. Yamaguchi A., Ishibashi H., Kohra S., Arizono K., and Tominaga N. Short-term effects of endocrine-disrupting chemicals on the expression of estrogen-responsive genes in male medaka (Oryzias latipes). Aquat. Toxicol. 72 (2005) 239-249
47. Yin G.G., Kookana R.S., and Ru Y.J. Occurrence and fate of hormone steroids in the environment. Environ. Int. 28 6 (2002) 545-551