Evolution of pharmacologic specificity in the pregnane X receptor

BMC Evolutionary Biology

Volumn 8, Issue 1, 2008, Pages

  Ekins, Sean ^a,b,c   Reschly, Erica J ^d   Hagey, Lee R ^e   Krasowski, Matthew D ^d  

^a Collaborations in Chemistry Inc ^*  (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTANE DERIVATIVE; BENZOIC ACID DERIVATIVE; CARBAZOLE DERIVATIVE; ESTRANE DERIVATIVE; PREGNANE X RECEPTOR; STEROID; VITAMIN; VITAMIN D RECEPTOR; XENOBIOTIC AGENT; LIGAND; STEROID RECEPTOR;

AGONIST; AMINO ACID SEQUENCE; ARTICLE; CHICKEN; CIONA INTESTINALIS; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HYDROGEN BOND; LIGAND BINDING; MOLECULAR CLONING; MOLECULAR EVOLUTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHARMACOPHORE; PHYLOGENY; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; RABBIT; RAT; STRUCTURAL HOMOLOGY; VERTEBRATE; XENOPUS; ZEBRA FISH; ANIMAL; CHEMISTRY; DRUG POTENTIATION; GENETICS; SPECIES DIFFERENCE; STATISTICAL MODEL;

AVES; CIONA; CIONA INTESTINALIS; DANIO RERIO; INVERTEBRATA; MAMMALIA; ORYCTOLAGUS CUNICULUS; RATTUS; VERTEBRATA; XENOPUS LAEVIS; XENOPUS TROPICALIS;

AMINO ACID SEQUENCE; ANIMALS; EVOLUTION, MOLECULAR; HUMANS; LIGANDS; LIKELIHOOD FUNCTIONS; PHYLOGENY; RECEPTORS, STEROID; SPECIES SPECIFICITY;

EID: 42949106570     PISSN: None     EISSN: 14712148     Source Type: Journal    
DOI: 10.1186/1471-2148-8-103     Document Type: Article

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