Effects of the antidepressant mianserin in zebrafish: Molecular markers of endocrine disruption

Chemosphere

Volumn 65, Issue 10, 2006, Pages 1836-1845

  van der Ven, Karlijn ^a   Keil, Dorien ^a   Moens, Lotte N ^a   Hummelen, Paul Van ^c   van Remortel, Piet ^b   Maras, Marleen ^a   De Coen, Wim ^a  

^a Ecophysiology   (Belgium)

^b UNIVERSITY OF ANTWERP   (Belgium)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

Mianserin; Oligo microarray; Pharmaceuticals; Toxicogenomics; Zebrafish

Indexed keywords

MIANSERIN; OLIGO MICROARRAY; TOXICOGENOMICS; ZEBRAFISH;

BIOMARKERS; DNA; DRUG PRODUCTS; GENES; TISSUE; TOXICITY;

POLLUTION DETECTION;

ANTIDEPRESSANT AGENT; COMPLEMENTARY DNA; ENDOCRINE DISRUPTOR; ESTROGEN; MIANSERIN; MOLECULAR MARKER; VITELLOGENIN;

BIOMARKERS; DNA; DRUG PRODUCTS; GENES; POLLUTION DETECTION; TISSUE; TOXICITY;

DRUG; ECOTOXICOLOGY; ENDOCRINE DISRUPTOR; FISH; GENE EXPRESSION;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CONTROLLED STUDY; DNA HYBRIDIZATION; DNA MICROARRAY; DRUG EFFECT; ECOTOXICOLOGY; FEMALE; GENE EXPRESSION; GENETIC ANALYSIS; GONAD; HORMONE ACTION; HYPOTHALAMUS HYPOPHYSIS SYSTEM; LIFE CYCLE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; SEROTONINERGIC SYSTEM; SIGNAL TRANSDUCTION; ZEBRA FISH; ZONA PELLUCIDA;

ANIMALS; ANTIDEPRESSIVE AGENTS; BIOLOGICAL MARKERS; BRAIN; EMBRYO, NONMAMMALIAN; ENDOCRINE DISRUPTORS; FEMALE; GENE EXPRESSION REGULATION; MALE; MIANSERIN; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OVARY; POLYMERASE CHAIN REACTION; TESTIS; VITELLOGENINS; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO;

EID: 33750072337     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2006.03.079     Document Type: Article

References (39)

1. Ankley G.T., and Johnson R.D. Small fish models for identifying and assessing the effects of endocrine-disruptive chemicals. ILAR J. 45 (2004) 469-483
2. Ansar Ahmed S. The immune system as a potential target for environmental estrogens (endocrine disrupters): a new emerging field. Toxicology 150 (2000) 191-206
3. Arcand-Hoy L.D., and Benson W.H. Toxic responses of the reproductive system. In: Schlenk D., and Benson W.H. (Eds). Target Organ Toxicity in Marine and Freshwater Teleosts: Vol. 2 - Systems (2001), Taylor and Francis 175-202
4. Arcand-Hoy L.D., and Benson W.H. Fish reproduction: An ecologically relevant indicator of endocrine disruption. Environ. Toxicol. Chem. 17 (1998) 49-57
5. Berg A.H., Westerlund L., and Olsson P.E. Regulation of Arctic char (Salvenius alpinus) egg shell proteins and vitellogenin during reproduction and in response to 17β-estradiol and cortisol. Gen. Comp. Endocr. 135 (2004) 276-285
6. Brooks B.W., Turner P.K., Stanley J.K., Weston J.J., Glidewell E.A., Foran C.M., Slattery M., La Point T.W., and Huggett D.B. Waterborne and sediment toxicity of fluoxetine to select organisms. Chemosphere 52 (2003) 135-142
7. Brooks B.W., Foran C.M., Richards S.M., Weston J., Turner P.K., Stanley J.K., Solomon K.R., Slattery M., and La Point T.W. Aquatic toxicology of fluoxetine. Toxicol. Lett. 142 (2003) 169-183
8. Brooks B.W., Chambliss C.K., Stanley J.K., Ramirez A., Banks K.E., Johnson R.D., and Lewis R.J. Determination of select antidepressants in fish from an affluent-dominated stream. Environ. Toxicol. Chem. 24 (2005) 464-469
9. Carter S.L., Eklund A.C., Mecham B.H., Kohane I.S., and Szallasi Z. Redefinition of Afflymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in cancer-associated gene expression measurements. BMC Bioinformatics 6 (2005) 107
10. Cerdà J., Subhedar N., Reich G., Wallace R.A., and Selman K. Oocyte sensitivity to serotonergic regulation during the follicular cycle of the teleost Fundulus heteroclitus. Biol. Reprod. 59 (1998) 53-61
11. Dolberg O.T., Klag E., Gross Y., and Schreiber S. Relief of serotonin selective reuptake inhibitor induced sexual dysfunction with low-dose mianserin in patients with traumatic brain injury. Psychopharmacology 161 (2002) 404-407
12. Dreanno C., Cosson J., Suquet M., Sequin F., Dorange G., and Billard R. Nucleotide content, oxidative phosphorylation, morphology, and fertilization capacity of tubot (Psetta maxima) spermatozoa during the motility period. Mol. Reprod. Dev. 53 (1999) 230-243
13. Ferrari B., Mond R., Vollat B., Fraysse B., Paxéus N., Lo Giudice R., Pollio A., and Garric J. Environmental risk assessment of six human pharmaceuticals: are the current environmental risk assessment procedures sufficient for the protection of the aquatic environment?. Environ. Toxicol. Chem. 23 (2004) 1344-1354
14. 2 receptor antagonists. J. Exp. Zool. 298A (2003) 67-72
15. Foran C.M., Weston J., Slattery M., Brooks W.M., and Huggett D.B. Reproductive assessment of Japanese medaka (Oryzias latipes) following a four-week fluoxetine (SSRI) exposure. Arch. Environ. Con. Tox. 46 (2004) 511-517
16. Halling-Sørensen B., Nors Nielsen S., Lanzky P.F., Ingerslev F., Holten Lützhøft H.-C., and Jørgensen S.E. Occurrence, fate and effects of pharmaceutical substances in the environment - a review. Chemosphere 36 (1998) 357-393
17. Heiske A., Jesberg J., Krieg J.-C., and Vedder H. Differential effects of antidepressants on glucocorticoid receptors in human primary blood cells and human monocytic U-937 cells. Neuropsychopharmacology 28 (2003) 807-817
18. Henry T.B., Kwon J.-W., Armbrust K.L., and Black M.C. Acute and chronic toxicity of five selective serotonin reuptake inhibitors in Ceriodaphnia dubia. Environ. Toxicol. Chem. 23 (2004) 2229-2233
19. Hignite C., and Azarnoff D.L. Drugs and drug metabolites as environmental contaminants - Chlorophenoxyisobutyrate and salicylic acid in sewage water effluent. Life Sci. 20 (1977) 337-341
20. Kalman J., Palotas A., Juhasz A., Rimanoczy A., Hugyecz M., Kovacs Z., Galsi G., Szabo Z., Pakaski M., Feher L.Z., Janka Z., and Puskas L.G. Impact of venlafaxine on gene expression profile in lymphocytes of the elderly with major depression - evolution of antidepressants and the role of the "neuro-immune" system. Neurochem. Res. 30 (2005) 1429-1438
21. Larson E.T., Norris D.O., Grau E.G., and Summers C.H. Monoamines stimulate sex reversal in the saddleback wrasse. Gen. Comp. Endocr. 130 (2003) 289-298
22. Olejniczak K., and Spindler P. Environmental risk assessment of medicinal products for human use: aspects of its regulations in the European Union, Canada and United States. In: Kümmerer K. (Ed). Pharmaceuticals in the Environment (2004), Springer, Berlin, Germany 269-287
23. Park P.J., Cao Y.A., Lee S.Y., Kim J.-W., Chang M.S., Hart R., and Choi S. Current issues for DNA microarrays: platform comparison, double linear amplification, and universal RNA reference. J. Biotechnol. 112 (2004) 225-245
24. ©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res. 30 (2002) e36-e45
25. Reichert K., and Menzel R. Expression profiling of five different xenobiotics using a Caenorhabditis elegans whole genome microarray. Chemosphere 61 (2005) 229-237
26. Richards S.M., Wilson C.J., Johnson D.J., Castle D.M., Lam M., Mabury S.A., Sibley P.K., and Solomon K.R. Effects of pharmaceutical mixtures in aquatic microcosms. Environ. Toxicol. Chem. 23 (2004) 1035-1042
27. Rotchell J.M., and Ostrander G.K. Molecular markers of endocrine disruption in aquatic organisms. Toxicol. Environ. Health B Crit. Rev. 6 (2003) 453-496
28. Rupprecht R. Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties. Psychoneuroendocrinology 28 (2003) 139-168
29. Sammar M., Babin P.J., Durliat M., Meiri I., Zchori I., Elizur A., and Lubzens E. Retinol binding protein in rainbow trout: molecular properties and mRNA expression in tissues. Gen. Comp. Endocr. 123 (2001) 51-61
30. Somoza G.M., Yu K.L., and Peter R.E. Serotonin stimulates gonadotropin release in female and male goldfish, Carassius auratus L. Gen. Comp. Endocr. 72 (1988) 374-382
31. Sanderson H., Johnson D.J., Reitsma T., Brain R.A., Wilson C.J., and Solomon K.R. Ranking and prioritization of environmental risks of pharmaceuticals in surface waters. Regul. Toxicol. Pharm. 39 (2004) 158-183
32. Ternes T.A. Analytical methods for the determination of pharmaceuticals in aqueous environmental samples. Trends Anal. Chem. 20 (2001) 419-433
33. Van den Belt K., Verheyen R., and Witters H. Comparison of vitellogenin responses in zebrafish and rainbow trout following exposure to environmental estrogens. Ecotoxicol. Environ. Saf. 56 (2003) 271-281
34. van der Ven K., Van Dongen W., Maes B.U.W., Esmans E., Blust R., and De Coen W. Determination of diazepam in aquatic samples by capillary liquid chromatography - electrospray tandem mass spectrometry. Chemosphere 57 (2004) 967-973
35. van der Ven, K., Keil, D., De Wit, M., Moens, L., Van Leemput, K., van Remortel, P., De Coen, W. Neuropharmaceuticals in the environment: Mianserin induced neuro-endocrine disruption in zebrafish using cDNA microarrays. Environ. Toxicol. Chem., in press.
36. van der Ven K., De Witt M., Keil D., Moens L.N., Van Leemput K., Naudts B., and De Coen W. Development and application of a brain-specific cDNA microarray for effect evaluation of neuro-active pharmaceuticals in zebrafish (Danio rerio). Comp. Biochem. Physiol. B 141 (2005) 408-417
37. Vladić T.V., Afzelius B.A., and Bronnikov E. Sperm quality as reflected through morphology in salmon alternative life histories. Biol. Reprod. 66 (2002) 98-105
38. von Demling J. Mianserin: pharmacology and clinical aspects of an effective antidepressive agent. Fortschr. Med. 111 (1993) 497-500
39. Webb S. A database perspective on the ERA of human pharmaceuticals II - aquatic risk characterization. In: Kümmerer K. (Ed). Pharmaceuticals in the Aquatic Environment: Sources, Fate, Effects and Risks (2001), Springer-Verlag, Berlin, Germany 203-219