Comparative in vitro metabolism of benzo[a]pyrene by recombinant zebrafish CYP1A and liver microsomes from β-naphthoflavone-treated rainbow trout

Aquatic Toxicology

Volumn 80, Issue 2, 2006, Pages 101-108

  Miranda, C L ^a   Chung, W G ^a   Wang Buhler, J L ^a   Musafia Jeknic, T ^a   Baird, W M ^a   Buhler, D R ^a  

^a OREGON STATE UNIVERSITY   (United States)

Author keywords

CYP1A; Cytochrome P450; Danio rerio; DNA binding; Zebrafish

Indexed keywords

7,8 DIHYDRO 7,8 DIHYDROXYBENZO[A]PYRENE; 9,10 DIHYDRO 9,10 DIHYDROXYBENZO[A]PYRENE; BENZO[A]PYRENE; BENZO[A]PYRENE 7,8 DIHYDRODIOL 9,10 OXIDE; BENZO[A]PYRENE DERIVATIVE; BETA NAPHTHOFLAVONE; COMPLEMENTARY DNA; CYTOCHROME P450; CYTOCHROME P450 1A; EPOXIDE HYDROLASE; PHENOL; POLYCYCLIC AROMATIC HYDROCARBON; QUINONE DERIVATIVE; UNCLASSIFIED DRUG;

CARCINOGEN; CYTOCHROME; DNA; ECOTOXICOLOGY; ENZYME ACTIVITY; FISH; PAH; RECOMBINATION;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARCINOGENIC ACTIVITY; CONTROLLED STUDY; DETOXIFICATION; DNA ADDUCT; DNA BINDING; ENZYME ACTIVATION; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; INCUBATION TIME; LIVER METABOLISM; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RAINBOW TROUT; ZEBRA FISH;

ANIMALS; BENZO(A)PYRENE; CARBON ISOTOPES; CYTOCHROME P-450 ENZYME SYSTEM; DNA; MICROSOMES, LIVER; ONCORHYNCHUS MYKISS; PHOSPHORUS ISOTOPES; PROTEIN BINDING; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; ZEBRAFISH PROTEINS;

DANIO RERIO; MAMMALIA; ONCORHYNCHUS MYKISS; SALMONIDAE;

EID: 33750040263     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2006.07.018     Document Type: Article

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