Uncoupling of cytochrome P450 1A and stimulation of reactive oxygen species production by co-planar polychlorinated biphenyl congeners

Aquatic Toxicology

Volumn 77, Issue 4, 2006, Pages 422-432

  Schlezinger, Jennifer J ^a   Struntz, William D J ^a   Goldstone, Jared V ^a   Stegeman, John J ^a  

^a WOODS HOLE OCEANOGRAPHIC INSTITUTION   (United States)

Author keywords

CYP1A; Oxidative inactivation; Planar halogenated aromatic hydrocarbons; Reactive oxygen species

Indexed keywords

2 (2,3,3',4,4' PENTACHLOROBIPHENYL); 3,3',4,4',5 PENTACHLOROBIPHENYL; 3,3',4,4',5,5' HEXACHLOROBIPHENYL; AROMATIC HYDROCARBON; AROMATIC HYDROCARBON RECEPTOR; BENZO[A]PYRENE; CYTOCHROME P450 1A; DI 2 (2,2',5,5' TETRACHLOROBIPHENYL); ETHOXYRESORUFIN DEETHYLASE; OXYGEN; POLYCHLORINATED BIPHENYL; POLYCHLORINATED BIPHENYL DERIVATIVE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

AROMATIC HYDROCARBON; CYTOCHROME; HALOGENATED HYDROCARBON; PCB; TOXICITY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; FISH; HALOGENATION; HYPOTHESIS; LIVER MICROSOME; MAMMAL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMALS; AZIDES; BENZO(A)PYRENE; CYTOCHROME P-450 ENZYME SYSTEM; ELECTRON TRANSPORT; HYDROGEN PEROXIDE; MICROSOMES, LIVER; NADP; OXIDATION-REDUCTION; PERCIFORMES; POLYCHLORINATED BIPHENYLS; REACTIVE OXYGEN SPECIES; SPECTROPHOTOMETRY; UNCOUPLING AGENTS;

ANIMALIA; MAMMALIA; STENOTOMUS CHRYSOPS;

EID: 33646141609     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2006.01.012     Document Type: Article

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