메뉴 건너뛰기




Volumn , Issue , 2007, Pages 667-702

Mitochondrial permeability transition in the CNS - Composition, regulation, and pathophysiological relevance

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84900975500     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-0-387-30411-3_25     Document Type: Chapter
Times cited : (9)

References (344)
  • 1
    • 1542315514 scopus 로고    scopus 로고
    • The effects of monobromobimane on neuronal cell death in the hippocampus after transient global cerebral ischemia in rats
    • Abe T, Takagi N, Nakano M, Takeo S. 2004. The effects of monobromobimane on neuronal cell death in the hippocampus after transient global cerebral ischemia in rats. Neurosci Lett 357:227-231.
    • (2004) Neurosci Lett , vol.357 , pp. 227-231
    • Abe, T.1    Takagi, N.2    Nakano, M.3    Takeo, S.4
  • 2
    • 0024963096 scopus 로고
    • Further characterization of contact sites from mitochondria of different tissues: Topology of peripheral kinases
    • Adams V, Bosch W, Schlegel J, Wallimann T, Brdiczka D. 1989. Further characterization of contact sites from mitochondria of different tissues: Topology of peripheral kinases. Biochim Biophys Acta 981:213-225.
    • (1989) Biochim Biophys Acta , vol.981 , pp. 213-225
    • Adams, V.1    Bosch, W.2    Schlegel, J.3    Wallimann, T.4    Brdiczka, D.5
  • 3
    • 33644865615 scopus 로고    scopus 로고
    • Neuroprotective effects of propofol in models of cerebral ischemia: Inhibition of mitochondrial swelling as a possible mechanism
    • Adembri C, Venturi L, Tani A, Chiarugi A, Gramigni E, et al. 2006. Neuroprotective effects of propofol in models of cerebral ischemia: Inhibition of mitochondrial swelling as a possible mechanism. Anesthesiology 104:80-89.
    • (2006) Anesthesiology , vol.104 , pp. 80-89
    • Adembri, C.1    Venturi, L.2    Tani, A.3    Chiarugi, A.4    Gramigni, E.5
  • 4
    • 0022931338 scopus 로고
    • 2+-induced permeabilization of rat liver mitochondria
    • 2+-induced permeabilization of rat liver mitochondria. Biochem J 239:19-29.
    • (1986) Biochem J , vol.239 , pp. 19-29
    • Al-Nasser, I.1    Crompton, M.2
  • 5
    • 0036488223 scopus 로고    scopus 로고
    • Mitochondrial permeability transition and calcium dynamics in striatal neurons upon intense NMDA receptor activation
    • Alano CC, Beutner G, Dirksen RT, Gross RA, Sheu SS. 2002. Mitochondrial permeability transition and calcium dynamics in striatal neurons upon intense NMDA receptor activation. J Neurochem 80:531-538.
    • (2002) J Neurochem , vol.80 , pp. 531-538
    • Alano, C.C.1    Beutner, G.2    Dirksen, R.T.3    Gross, R.A.4    Sheu, S.S.5
  • 6
    • 0036329446 scopus 로고    scopus 로고
    • Cyclosporin A improves brain tissue oxygen consumption and learning/memory performance after lateral fluid percussion injury in rats
    • Alessandri B, Rice AC, Levasseur J, DeFord M, Hamm RJ, et al. 2002. Cyclosporin A improves brain tissue oxygen consumption and learning/memory performance after lateral fluid percussion injury in rats. J Neurotrauma 19:829-841.
    • (2002) J Neurotrauma , vol.19 , pp. 829-841
    • Alessandri, B.1    Rice, A.C.2    Levasseur, J.3    De Ford, M.4    Hamm, R.J.5
  • 7
    • 0029810955 scopus 로고    scopus 로고
    • Carboxyatractylate- and cyclosporin A-sensitive uncoupling in liver mitochondria of ground squirrels during hibernation and arousal
    • Amerkhanov ZG, Yegorova MV, Markova OV, Mokhova EN. 1996. Carboxyatractylate- and cyclosporin A-sensitive uncoupling in liver mitochondria of ground squirrels during hibernation and arousal. Biochem Mol Biol Int 38:863-870.
    • (1996) Biochem Mol Biol Int , vol.38 , pp. 863-870
    • Amerkhanov, Z.G.1    Yegorova, M.V.2    Markova, O.V.3    Mokhova, E.N.4
  • 8
    • 0036313070 scopus 로고    scopus 로고
    • The effects of focal ischemia and reperfusion on the glutathione content of mitochondria from rat brain subregions
    • Anderson MF, Sims NR. 2002. The effects of focal ischemia and reperfusion on the glutathione content of mitochondria from rat brain subregions. J Neurochem 81:541-549.
    • (2002) J Neurochem , vol.81 , pp. 541-549
    • Anderson, M.F.1    Sims, N.R.2
  • 9
    • 3142713361 scopus 로고    scopus 로고
    • Direct inhibition of the mitochondrial permeability transition pore: A possible mechanism responsible for antiapoptotic effects of melatonin
    • Andrabi SA, Sayeed I, Siemen D, Wolf G, Horn TF. 2004. Direct inhibition of the mitochondrial permeability transition pore: A possible mechanism responsible for antiapoptotic effects of melatonin. FASEB J 18:869-871.
    • (2004) FASEB J , vol.18 , pp. 869-871
    • Andrabi, S.A.1    Sayeed, I.2    Siemen, D.3    Wolf, G.4    Horn, T.F.5
  • 10
    • 0031788661 scopus 로고    scopus 로고
    • Cytochrome c release from brain mitochondria is independent of the mitochondrial permeability transition
    • Andreyev AY, Fahy B, Fiskum G. 1998. Cytochrome c release from brain mitochondria is independent of the mitochondrial permeability transition. FEBS Lett 439:373-376.
    • (1998) FEBS Lett , vol.439 , pp. 373-376
    • Andreyev, A.Y.1    Fahy, B.2    Fiskum, G.3
  • 11
    • 0022574416 scopus 로고
    • The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane
    • Anholt RR, Pedersen PL, De Souza EB, Snyder SH. 1986. The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane. J Biol Chem 261:576-583.
    • (1986) J Biol Chem , vol.261 , pp. 576-583
    • Anholt, R.R.1    Pedersen, P.L.2    De Souza, E.B.3    Snyder, S.H.4
  • 12
    • 33645420460 scopus 로고    scopus 로고
    • Mitochondrial membrane permeabilization: The sine qua non for cell death
    • Armstrong JS. 2006. Mitochondrial membrane permeabilization: The sine qua non for cell death. Bioessays 28:253-260.
    • (2006) Bioessays , vol.28 , pp. 253-260
    • Armstrong, J.S.1
  • 13
    • 0036289498 scopus 로고    scopus 로고
    • Minocycline markedly protects the neonatal brain against hypoxic-ischemic injury
    • Arvin KL, Han BH, Du Y, Lin SZ, Paul SM, et al. 2002. Minocycline markedly protects the neonatal brain against hypoxic-ischemic injury. Ann Neurol 52:54-61.
    • (2002) Ann Neurol , vol.52 , pp. 54-61
    • Arvin, K.L.1    Han, B.H.2    Du, Y.3    Lin, S.Z.4    Paul, S.M.5
  • 15
    • 0942290437 scopus 로고    scopus 로고
    • In self-defence: Hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death
    • Azoulay-Zohar H, Israelson A, Abu-Hamad S, Shoshan-Barmatz V. 2004. In self-defence: Hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death. Biochem J 377:347-355.
    • (2004) Biochem J , vol.377 , pp. 347-355
    • Azoulay-Zohar, H.1    Israelson, A.2    Abu-Hamad, S.3    Shoshan-Barmatz, V.4
  • 16
    • 0013853324 scopus 로고
    • Swelling and shrinkage phenomena in liver mitochondria. I. Large amplitude swelling induced by inorganic phosphate and by ATP
    • Azzi A, Azzone GF. 1965. Swelling and shrinkage phenomena in liver mitochondria. I. Large amplitude swelling induced by inorganic phosphate and by ATP. Biochim Biophys Acta 105:253-264.
    • (1965) Biochim Biophys Acta , vol.105 , pp. 253-264
    • Azzi, A.1    Azzone, G.F.2
  • 17
    • 0035577916 scopus 로고    scopus 로고
    • Ammonia induces the mitochondrial permeability transition in primary cultures of rat astrocytes
    • Bai G, Rama Rao KV, Murthy CR, Panickar KS, Jayakumar AR, et al. 2001. Ammonia induces the mitochondrial permeability transition in primary cultures of rat astrocytes. J Neurosci Res 66:981-991.
    • (2001) J Neurosci Res , vol.66 , pp. 981-991
    • Bai, G.1    Rama Rao, K.V.2    Murthy, C.R.3    Panickar, K.S.4    Jayakumar, A.R.5
  • 18
    • 15844375853 scopus 로고    scopus 로고
    • Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
    • Baines CP, Kaiser RA, Purcell NH, Blair NS, Osinska H, et al. 2005. Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature 434:658-662.
    • (2005) Nature , vol.434 , pp. 658-662
    • Baines, C.P.1    Kaiser, R.A.2    Purcell, N.H.3    Blair, N.S.4    Osinska, H.5
  • 19
    • 1542317747 scopus 로고    scopus 로고
    • Astrocyte mitochondrial mechanisms of ischemic brain injury and neuroprotection
    • Bambrick L, Kristian T, Fiskum G. 2004. Astrocyte mitochondrial mechanisms of ischemic brain injury and neuroprotection. Neurochem Res 29:601-608.
    • (2004) Neurochem Res , vol.29 , pp. 601-608
    • Bambrick, L.1    Kristian, T.2    Fiskum, G.3
  • 20
    • 33746081243 scopus 로고    scopus 로고
    • Cyclosporin A increases mitochondrial calcium uptake capacity in cortical astrocytes but not cerebellar granule neurons
    • Bambrick LL, Chandrasekaran K, Mehrabian Z, Wright C, Krueger BK, et al. 2006. Cyclosporin A increases mitochondrial calcium uptake capacity in cortical astrocytes but not cerebellar granule neurons. J Bioenerg Biomembr 38:43-47.
    • (2006) J Bioenerg Biomembr , vol.38 , pp. 43-47
    • Bambrick, L.L.1    Chandrasekaran, K.2    Mehrabian, Z.3    Wright, C.4    Krueger, B.K.5
  • 21
    • 21244446551 scopus 로고    scopus 로고
    • Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D
    • Basso E, Fante L, Fowlkes J, Petronilli V, Forte MA, et al. 2005. Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D. J Biol Chem 280:18558-18561.
    • (2005) J Biol Chem , vol.280 , pp. 18558-18561
    • Basso, E.1    Fante, L.2    Fowlkes, J.3    Petronilli, V.4    Forte, M.A.5
  • 22
    • 0033611057 scopus 로고    scopus 로고
    • Adenine nucleotide translocase-1, a component of the permeability transition pore, can dominantly induce apoptosis
    • Bauer MK, Schubert A, Rocks O, Grimm S. 1999. Adenine nucleotide translocase-1, a component of the permeability transition pore, can dominantly induce apoptosis. J Cell Biol 147:1493-1502.
    • (1999) J Cell Biol , vol.147 , pp. 1493-1502
    • Bauer, M.K.1    Schubert, A.2    Rocks, O.3    Grimm, S.4
  • 23
    • 0032504710 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in neurodegenerative diseases
    • Beal MF. 1998. Mitochondrial dysfunction in neurodegenerative diseases. Biochim Biophys Acta 1366:211-223.
    • (1998) Biochim Biophys Acta , vol.1366 , pp. 211-223
    • Beal, M.F.1
  • 24
    • 0019971795 scopus 로고
    • 2+ release induced by t-butyl hydroperoxide or oxalacetate. The effect of ruthenium red
    • 2+ release induced by t-butyl hydroperoxide or oxalacetate. The effect of ruthenium red. J Biol Chem 257:7161-7171.
    • (1982) J Biol Chem , vol.257 , pp. 7161-7171
    • Beatrice, M.C.1    Stiers, D.L.2    Pfeiffer, D.R.3
  • 25
    • 0034535252 scopus 로고    scopus 로고
    • Quantitative biochemical and ultrastructural comparison of mitochondrial permeability transition in isolated brain and liver mitochondria: Evidence for reduced sensitivity of brain mitochondria
    • Berman SB, Watkins SC, Hastings TG. 2000. Quantitative biochemical and ultrastructural comparison of mitochondrial permeability transition in isolated brain and liver mitochondria: Evidence for reduced sensitivity of brain mitochondria. Exp Neurol 164:415-425.
    • (2000) Exp Neurol , vol.164 , pp. 415-425
    • Berman, S.B.1    Watkins, S.C.2    Hastings, T.G.3
  • 26
    • 0026801183 scopus 로고
    • Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by the proton electrochemical gradient. Evidence that the pore can be opened by membrane depolarization
    • Bernardi P. 1992. Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by the proton electrochemical gradient. Evidence that the pore can be opened by membrane depolarization. J Biol Chem 267:8834-8839.
    • (1992) J Biol Chem , vol.267 , pp. 8834-8839
    • Bernardi, P.1
  • 27
    • 0032827410 scopus 로고    scopus 로고
    • Mitochondrial transport of cations: Channels, exchangers, and permeability transition
    • Bernardi P. 1999. Mitochondrial transport of cations: Channels, exchangers, and permeability transition. Physiol Rev 79:1127-1155.
    • (1999) Physiol Rev , vol.79 , pp. 1127-1155
    • Bernardi, P.1
  • 28
    • 0029998621 scopus 로고    scopus 로고
    • The permeability transition pore as a mitochondrial calcium release channel: A critical appraisal
    • Bernardi P, Petronilli V. 1996. The permeability transition pore as a mitochondrial calcium release channel: A critical appraisal. J Bioenerg Biomembr 28:131-138.
    • (1996) J Bioenerg Biomembr , vol.28 , pp. 131-138
    • Bernardi, P.1    Petronilli, V.2
  • 29
    • 0028053663 scopus 로고
    • Recent progress onregulationof the mitochondrial permeability transition pore, a cyclosporin-sensitive pore in the inner mitochondrial membrane
    • Bernardi P, Broekemeier KM, Pfeiffer DR. 1994. Recent progress onregulationof the mitochondrial permeability transition pore, a cyclosporin-sensitive pore in the inner mitochondrial membrane. J Bioenerg Biomembr 26:509-517.
    • (1994) J Bioenerg Biomembr , vol.26 , pp. 509-517
    • Bernardi, P.1    Broekemeier, K.M.2    Pfeiffer, D.R.3
  • 30
    • 33646255246 scopus 로고    scopus 로고
    • The mitochondrial permeability transition from in vitro artifact to disease target
    • Bernardi P, Krauskopf A, Basso E, Petronilli V, Blalchy-Dyson E, et al. 2006. The mitochondrial permeability transition from in vitro artifact to disease target. FEBS J 273:2077-2099.
    • (2006) FEBS J , vol.273 , pp. 2077-2099
    • Bernardi, P.1    Krauskopf, A.2    Basso, E.3    Petronilli, V.4    Blalchy-Dyson, E.5
  • 32
    • 0026687312 scopus 로고
    • Modulation of the mitochondrial permeability transition pore. Effect of protons and divalent cations
    • Bernardi P, Vassanelli S, Veronese P, Colonna R, Szabo I, et al. 1992. Modulation of the mitochondrial permeability transition pore. Effect of protons and divalent cations. J Biol Chem 267:2934-2939.
    • (1992) J Biol Chem , vol.267 , pp. 2934-2939
    • Bernardi, P.1    Vassanelli, S.2    Veronese, P.3    Colonna, R.4    Szabo, I.5
  • 33
    • 0034768233 scopus 로고    scopus 로고
    • Toxicity of alpidem, a peripheral benzodiazepine receptor ligand, but not zolpidem, in rat hepatocytes: Role of mitochondrial permeability transition and metabolic activation
    • Berson A, Descatoire V, Sutton A, Fau D, Maulny B, et al. 2001. Toxicity of alpidem, a peripheral benzodiazepine receptor ligand, but not zolpidem, in rat hepatocytes: Role of mitochondrial permeability transition and metabolic activation. J Pharmacol Exp Ther 299:793-800.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 793-800
    • Berson, A.1    Descatoire, V.2    Sutton, A.3    Fau, D.4    Maulny, B.5
  • 34
    • 0344653616 scopus 로고    scopus 로고
    • Complexes between porin, hexokinase, mitochondrial creatine kinase, and adenylate translocator display properties of the permeability transition pore. Implication for regulation of permeability transition by the kinases
    • Beutner G, Ruck A, Riede B, Brdiczka D. 1998. Complexes between porin, hexokinase, mitochondrial creatine kinase, and adenylate translocator display properties of the permeability transition pore. Implication for regulation of permeability transition by the kinases. Biochim Biophys Acta 1368:7-18.
    • (1998) Biochim Biophys Acta , vol.1368 , pp. 7-18
    • Beutner, G.1    Ruck, A.2    Riede, B.3    Brdiczka, D.4
  • 35
    • 0030569305 scopus 로고    scopus 로고
    • Complexes between kinases, mitochondrial porin, and adenylate translocator in rat brain resemble the permeability transition pore
    • Beutner G, Ruck A, Riede B, Welte W, Brdiczka D. 1996. Complexes between kinases, mitochondrial porin, and adenylate translocator in rat brain resemble the permeability transition pore. FEBS Lett 396:189-195.
    • (1996) FEBS Lett , vol.396 , pp. 189-195
    • Beutner, G.1    Ruck, A.2    Riede, B.3    Welte, W.4    Brdiczka, D.5
  • 37
    • 31344439662 scopus 로고    scopus 로고
    • Free radicals, mitochondria, and hypoxia-ischemia in the developing brain
    • Blomgren K, Hagberg H. 2006. Free radicals, mitochondria, and hypoxia-ischemia in the developing brain. Free Radic Biol Med 40:388-397.
    • (2006) Free Radic Biol Med , vol.40 , pp. 388-397
    • Blomgren, K.1    Hagberg, H.2
  • 39
    • 29344439984 scopus 로고    scopus 로고
    • Mitochondrial contact sites: Their role in energy metabolism and apoptosis
    • Brdiczka DG, Zorov DB, Sheu SS. 2006. Mitochondrial contact sites: Their role in energy metabolism and apoptosis. Biochim Biophys Acta 1762:148-163.
    • (2006) Biochim Biophys Acta , vol.1762 , pp. 148-163
    • Brdiczka, D.G.1    Zorov, D.B.2    Sheu, S.S.3
  • 40
    • 0034688175 scopus 로고    scopus 로고
    • Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator
    • Brenner C, Cadiou H, Vieira HL, Zamzami N, Marzo I, et al. 2000. Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator. Oncogene 19:329-336.
    • (2000) Oncogene , vol.19 , pp. 329-336
    • Brenner, C.1    Cadiou, H.2    Vieira, H.L.3    Zamzami, N.4    Marzo, I.5
  • 41
    • 0024435739 scopus 로고
    • Cyclosporin A-sensitive and insensitive mechanisms produce the permeability transition in mitochondria
    • Broekemeier KM, Pfeiffer DR. 1989. Cyclosporin A-sensitive and insensitive mechanisms produce the permeability transition in mitochondria. Biochem Biophys Res Commun 163:561-566.
    • (1989) Biochem Biophys Res Commun , vol.163 , pp. 561-566
    • Broekemeier, K.M.1    Pfeiffer, D.R.2
  • 42
    • 0029561991 scopus 로고
    • Inhibition of the mitochondrial permeability transition by cyclosporin A during long time frame experiments: Relationship between pore opening and the activity of mitochondrial phospholipases
    • Broekemeier KM, Pfeiffer DR. 1995. Inhibition of the mitochondrial permeability transition by cyclosporin A during long time frame experiments: Relationship between pore opening and the activity of mitochondrial phospholipases. Biochemistry 34:16440-16449.
    • (1995) Biochemistry , vol.34 , pp. 16440-16449
    • Broekemeier, K.M.1    Pfeiffer, D.R.2
  • 44
    • 0024360271 scopus 로고
    • Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria
    • Broekemeier KM, Dempsey ME, Pfeiffer DR. 1989. Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria. J Biol Chem 264:7826-7830.
    • (1989) J Biol Chem , vol.264 , pp. 7826-7830
    • Broekemeier, K.M.1    Dempsey, M.E.2    Pfeiffer, D.R.3
  • 46
    • 0030919567 scopus 로고    scopus 로고
    • Oxidative damage and metabolic dysfunction in Huntington's disease: Selective vulnerability of the basal ganglia
    • Browne SE, Bowling AC, MacGarvey U, Baik MJ, Berger SC, et al. 1997. Oxidative damage and metabolic dysfunction in Huntington's disease: Selective vulnerability of the basal ganglia. Ann Neurol 41:646-653.
    • (1997) Ann Neurol , vol.41 , pp. 646-653
    • Browne, S.E.1    Bowling, A.C.2    MacGarvey, U.3    Baik, M.J.4    Berger, S.C.5
  • 47
    • 0033995265 scopus 로고    scopus 로고
    • Dual responses of CNS mitochondria to elevated calcium
    • Brustovetsky N, Dubinsky JM. 2000. Dual responses of CNS mitochondria to elevated calcium. J Neurosci 20:103-113.
    • (2000) J Neurosci , vol.20 , pp. 103-113
    • Brustovetsky, N.1    Dubinsky, J.M.2
  • 49
    • 0035145453 scopus 로고    scopus 로고
    • On the mechanisms of neuroprotection by creatine and phosphocreatine
    • Brustovetsky N, Brustovetsky T, Dubinsky JM. 2001. On the mechanisms of neuroprotection by creatine and phosphocreatine. J Neurochem 76:425-434.
    • (2001) J Neurochem , vol.76 , pp. 425-434
    • Brustovetsky, N.1    Brustovetsky, T.2    Dubinsky, J.M.3
  • 50
    • 0036313059 scopus 로고    scopus 로고
    • Calcium-induced cytochrome c release from CNS mitochondria is associated with the permeability transition and rupture of the outer membrane
    • Brustovetsky N, Brustovetsky T, Jemmerson R, Dubinsky JM. 2002a. Calcium-induced cytochrome c release from CNS mitochondria is associated with the permeability transition and rupture of the outer membrane. J Neurochem 80:207-218.
    • (2002) J Neurochem , vol.80 , pp. 207-218
    • Brustovetsky, N.1    Brustovetsky, T.2    Jemmerson, R.3    Dubinsky, J.M.4
  • 51
    • 0036771787 scopus 로고    scopus 로고
    • 2+-dependent channel formed by recombinant ADP/ATP carrier from Neurospora crassa resembles the mitochondrial permeability transition pore
    • 2+-dependent channel formed by recombinant ADP/ATP carrier from Neurospora crassa resembles the mitochondrial permeability transition pore. Biochemistry 41:11804-11811.
    • (2002) Biochemistry , vol.41 , pp. 11804-11811
    • Brustovetsky, N.1    Tropschug, M.2    Heimpel, S.3    Heidkamper, D.4    Klingenberg, M.5
  • 52
    • 0037741021 scopus 로고    scopus 로고
    • Increased susceptibility of striatal mitochondria to calcium-induced permeability transition
    • Brustovetsky N, Brustovetsky T, Purl KJ, Capano M, Crompton M, et al. 2003a. Increased susceptibility of striatal mitochondria to calcium-induced permeability transition. J Neurosci 23:4858-4867
    • (2003) J Neurosci , vol.23 , pp. 4858-4867
    • Brustovetsky, N.1    Brustovetsky, T.2    Purl, K.J.3    Capano, M.4    Crompton, M.5
  • 53
    • 0037269346 scopus 로고    scopus 로고
    • Two pathways for tBID-induced cytochrome c release from rat brain mitochondria: BAK versus BAX-dependence
    • Brustovetsky N, Dubinsky JM, Antonsson B, Jemmerson R. 2003b. Two pathways for tBID-induced cytochrome c release from rat brain mitochondria: BAK versus BAX-dependence. J Neurochem 84:196-207.
    • (2003) J Neurochem , vol.84 , pp. 196-207
    • Brustovetsky, N.1    Dubinsky, J.M.2    Antonsson, B.3    Jemmerson, R.4
  • 54
    • 20744433946 scopus 로고    scopus 로고
    • Age-dependent changes in the calcium sensitivity of striatal mitochondria in mouse models of Huntington's disease
    • Brustovetsky N, LaFrance R, Purl KJ, Brustovetsky T, Keene CD, et al. 2005a. Age-dependent changes in the calcium sensitivity of striatal mitochondria in mouse models of Huntington's disease. J Neurochem 93:1361-1370.
    • (2005) J Neurochem , vol.93 , pp. 1361-1370
    • Brustovetsky, N.1    La France, R.2    Purl, K.J.3    Brustovetsky, T.4    Keene, C.D.5
  • 55
    • 23844509124 scopus 로고    scopus 로고
    • Activation of calcium-independent phospholipase A (iPLA) in brain mitochondria and release of apoptogenic factors by BAX and truncated BID
    • Brustovetsky T, Antonsson B, Jemmerson R, Dubinsky JM, Brustovetsky N. 2005b. Activation of calcium-independent phospholipase A (iPLA) in brain mitochondria and release of apoptogenic factors by BAX and truncated BID. J Neurochem 94:980-994.
    • (2005) J Neurochem , vol.94 , pp. 980-994
    • Brustovetsky, T.1    Antonsson, B.2    Jemmerson, R.3    Dubinsky, J.M.4    Brustovetsky, N.5
  • 56
    • 0027914395 scopus 로고
    • Cyclosporin A suppression of uncoupling in liver mitochondria of ground squirrel during arousal from hibernation
    • Brustovetsky NN, Egorova MV, Gnutov D, Mokhova EN, Skulachev VP. 1993. Cyclosporin A suppression of uncoupling in liver mitochondria of ground squirrel during arousal from hibernation. FEBS Lett 315:233-236.
    • (1993) FEBS Lett , vol.315 , pp. 233-236
    • Brustovetsky, N.N.1    Egorova, M.V.2    Gnutov, D.3    Mokhova, E.N.4    Skulachev, V.P.5
  • 57
    • 0037192787 scopus 로고    scopus 로고
    • Increased hexokinase activity, of either ectopic or endogenous origin, protects renal epithelial cells against acute oxidant-induced cell death
    • Bryson JM, Coy PE, Gottlob K, Hay N, Robey RB. 2002. Increased hexokinase activity, of either ectopic or endogenous origin, protects renal epithelial cells against acute oxidant-induced cell death. J Biol Chem 277:11392-11400.
    • (2002) J Biol Chem , vol.277 , pp. 11392-11400
    • Bryson, J.M.1    Coy, P.E.2    Gottlob, K.3    Hay, N.4    Robey, R.B.5
  • 58
    • 0345379310 scopus 로고    scopus 로고
    • Postinjury cyclosporin Aadministration limits axonal damage and disconnection in traumatic brain injury
    • Buki A, Okonkwo DO, Povlishock JT. 1999. Postinjury cyclosporin Aadministration limits axonal damage and disconnection in traumatic brain injury. J Neurotrauma 16:511-521.
    • (1999) J Neurotrauma , vol.16 , pp. 511-521
    • Buki, A.1    Okonkwo, D.O.2    Povlishock, J.T.3
  • 59
    • 0030850505 scopus 로고    scopus 로고
    • Neuroprotective actions of FK506 in experimental stroke: In vivo evidence against an antiexcitotoxic mechanism
    • Butcher SP, Henshall DC, Teramura Y, Iwasaki K, Sharkey J. 1997. Neuroprotective actions of FK506 in experimental stroke: In vivo evidence against an antiexcitotoxic mechanism. J Neurosci 17:6939-6946.
    • (1997) J Neurosci , vol.17 , pp. 6939-6946
    • Butcher, S.P.1    Henshall, D.C.2    Teramura, Y.3    Iwasaki, K.4    Sharkey, J.5
  • 60
    • 0141925705 scopus 로고    scopus 로고
    • Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation
    • Cao G, Clark RS, Pei W, Yin W, Zhang F, et al. 2003. Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation. J Cereb Blood Flow Metab 23:1137-1150.
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 1137-1150
    • Cao, G.1    Clark, R.S.2    Pei, W.3    Yin, W.4    Zhang, F.5
  • 61
    • 0032499885 scopus 로고    scopus 로고
    • Cyclosporin A increases resting mitochondrial membrane potential in SY5Y cells and reverses the depressed mitochondrial membrane potential of Alzheimer's disease cybrids
    • Cassarino DS, Swerdlow RH, Parks JK, Parker WD Jr., Bennett JP Jr. 1998. Cyclosporin A increases resting mitochondrial membrane potential in SY5Y cells and reverses the depressed mitochondrial membrane potential of Alzheimer's disease cybrids. Biochem Biophys Res Commun 248:168-173.
    • (1998) Biochem Biophys Res Commun , vol.248 , pp. 168-173
    • Cassarino, D.S.1    Swerdlow, R.H.2    Parks, J.K.3    Parker Jr., W.D.4    Bennett Jr., J.P.5
  • 62
    • 10744231632 scopus 로고    scopus 로고
    • The voltage-dependent anion channel is the target for a new class of inhibitors of the mitochondrial permeability transition pore
    • Cesura AM, Pinard E, Schubenel R, Goetschy V, Friedlein A, et al. 2003. The voltage-dependent anion channel is the target for a new class of inhibitors of the mitochondrial permeability transition pore. J Biol Chem 278:49812-49818.
    • (2003) J Biol Chem , vol.278 , pp. 49812-49818
    • Cesura, A.M.1    Pinard, E.2    Schubenel, R.3    Goetschy, V.4    Friedlein, A.5
  • 63
    • 0038143180 scopus 로고    scopus 로고
    • The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria
    • Chalmers S, Nicholls DG. 2003. The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria. J Biol Chem 278:19062-19070.
    • (2003) J Biol Chem , vol.278 , pp. 19062-19070
    • Chalmers, S.1    Nicholls, D.G.2
  • 64
    • 0035868944 scopus 로고    scopus 로고
    • Peripheral-type benzodiazepine receptor ligands: Mitochondrial permeability transition induction in rat cardiac tissue
    • Chelli B, Falleni A, Salvetti F, Gremigni V, Lucacchini A, et al. 2001. Peripheral-type benzodiazepine receptor ligands: Mitochondrial permeability transition induction in rat cardiac tissue. Biochem Pharmacol 61:695-705.
    • (2001) Biochem Pharmacol , vol.61 , pp. 695-705
    • Chelli, B.1    Falleni, A.2    Salvetti, F.3    Gremigni, V.4    Lucacchini, A.5
  • 65
    • 0033912716 scopus 로고    scopus 로고
    • Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease
    • Chen M, Ona VO, Li M, Ferrante RJ, Fink KB, et al. 2000. Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease. Nat Med 6:797-801.
    • (2000) Nat Med , vol.6 , pp. 797-801
    • Chen, M.1    Ona, V.O.2    Li, M.3    Ferrante, R.J.4    Fink, K.B.5
  • 67
    • 0030038762 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore is modulated by oxidative agents through both pyridine nucleotides and glutathione at two separate sites
    • Chernyak BV, Bernardi P. 1996. The mitochondrial permeability transition pore is modulated by oxidative agents through both pyridine nucleotides and glutathione at two separate sites. Eur J Biochem 238:623-630.
    • (1996) Eur J Biochem , vol.238 , pp. 623-630
    • Chernyak, B.V.1    Bernardi, P.2
  • 68
    • 0037891050 scopus 로고    scopus 로고
    • Cyclosporin A-insensitive permeability transition in brain mitochondria: Inhibition by 2-aminoethoxydiphenyl borate
    • Chinopoulos C, Starkov AA, Fiskum G. 2003. Cyclosporin A-insensitive permeability transition in brain mitochondria: Inhibition by 2-aminoethoxydiphenyl borate. J Biol Chem 278:27382-27389.
    • (2003) J Biol Chem , vol.278 , pp. 27382-27389
    • Chinopoulos, C.1    Starkov, A.A.2    Fiskum, G.3
  • 69
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi DW. 1988. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1:623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 70
    • 0037144409 scopus 로고    scopus 로고
    • Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin D at a different site from cyclosporin A
    • Clarke SJ, McStay GP, Halestrap AP. 2002. Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin D at a different site from cyclosporin A. J Biol Chem 277:34793-34799.
    • (2002) J Biol Chem , vol.277 , pp. 34793-34799
    • Clarke, S.J.1    McStay, G.P.2    Halestrap, A.P.3
  • 71
    • 9444254075 scopus 로고    scopus 로고
    • Neuroprotective effects of spermine following hypoxic-ischemic-induced brain damage: A mechanistic study
    • Clarkson AN, Liu H, Pearson L, Kapoor M, Harrison JC, et al. 2004. Neuroprotective effects of spermine following hypoxic-ischemic-induced brain damage: A mechanistic study. FASEB J 18:1114-1116.
    • (2004) FASEB J , vol.18 , pp. 1114-1116
    • Clarkson, A.N.1    Liu, H.2    Pearson, L.3    Kapoor, M.4    Harrison, J.C.5
  • 72
    • 27744532382 scopus 로고    scopus 로고
    • Promethazine protects against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine neurotoxicity
    • Cleren C, Starkov AA, Calingasan NY, Lorenzo BJ, Chen J, et al. 2005. Promethazine protects against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine neurotoxicity. Neurobiol Dis 20:701-708.
    • (2005) Neurobiol Dis , vol.20 , pp. 701-708
    • Cleren, C.1    Starkov, A.A.2    Calingasan, N.Y.3    Lorenzo, B.J.4    Chen, J.5
  • 73
    • 0034677715 scopus 로고    scopus 로고
    • Exogenous spermine reduces ischemic damage in a model of focal cerebral ischemia in the rat
    • Coert BA, Anderson RE, Meyer FB. 2000. Exogenous spermine reduces ischemic damage in a model of focal cerebral ischemia in the rat. Neurosci Lett 282:5-8.
    • (2000) Neurosci Lett , vol.282 , pp. 5-8
    • Coert, B.A.1    Anderson, R.E.2    Meyer, F.B.3
  • 74
    • 0033152431 scopus 로고    scopus 로고
    • Electron microscopic evidence against apoptosis as the mechanism of neuronal death in global ischemia
    • Colbourne F, Sutherland GR, Auer RN. 1999. Electron microscopic evidence against apoptosis as the mechanism of neuronal death in global ischemia. J Neurosci 19:4200-4210.
    • (1999) J Neurosci , vol.19 , pp. 4200-4210
    • Colbourne, F.1    Sutherland, G.R.2    Auer, R.N.3
  • 75
    • 0141483378 scopus 로고    scopus 로고
    • Cholesterol impairs the adenine nucleotide translocatormediated mitochondrial permeability transition through altered membrane fluidity
    • Colell A, Garcia-Ruiz C, Lluis JM, Coll O, Mari M, et al. 2003. Cholesterol impairs the adenine nucleotide translocatormediated mitochondrial permeability transition through altered membrane fluidity. J Biol Chem 278:33928-33935.
    • (2003) J Biol Chem , vol.278 , pp. 33928-33935
    • Colell, A.1    Garcia-Ruiz, C.2    Lluis, J.M.3    Coll, O.4    Mari, M.5
  • 76
    • 0026696585 scopus 로고
    • Purification and N-terminal sequencing of peptidyl-prolyl cis-trans-isomerase from rat liver mitochondrial matrix reveals the existence of a distinct mitochondrial cyclophilin
    • Connern CP, Halestrap AP. 1992. Purification and N-terminal sequencing of peptidyl-prolyl cis-trans-isomerase from rat liver mitochondrial matrix reveals the existence of a distinct mitochondrial cyclophilin. Biochem J 284(Pt 2), 381-385.
    • (1992) Biochem J , vol.284 , Issue.PART 2 , pp. 381-385
    • Connern, C.P.1    Halestrap, A.P.2
  • 77
    • 8844261855 scopus 로고    scopus 로고
    • Lack of evidence of direct mitochondrial involvement in the neuroprotective effect of minocycline
    • Cornet S, Spinnewyn B, Delaflotte S, Charnet C, Roubert V, et al. 2004. Lack of evidence of direct mitochondrial involvement in the neuroprotective effect of minocycline. Eur J Pharmacol 505:111-119.
    • (2004) Eur J Pharmacol , vol.505 , pp. 111-119
    • Cornet, S.1    Spinnewyn, B.2    Delaflotte, S.3    Charnet, C.4    Roubert, V.5
  • 78
    • 0028938858 scopus 로고
    • Selective inhibition of the mitochondrial permeability transition pore at the oxidation-reduction sensitive dithiol by monobromobimane
    • Costantini P, Chernyak BV, Petronilli V, Bernardi P. 1995. Selective inhibition of the mitochondrial permeability transition pore at the oxidation-reduction sensitive dithiol by monobromobimane. FEBS Lett 362:239-242.
    • (1995) FEBS Lett , vol.362 , pp. 239-242
    • Costantini, P.1    Chernyak, B.V.2    Petronilli, V.3    Bernardi, P.4
  • 79
    • 0029863399 scopus 로고    scopus 로고
    • Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites
    • Costantini P, Chernyak BV, Petronilli V, Bernardi P. 1996. Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites. J Biol Chem 271:6746-6751.
    • (1996) J Biol Chem , vol.271 , pp. 6746-6751
    • Costantini, P.1    Chernyak, B.V.2    Petronilli, V.3    Bernardi, P.4
  • 80
    • 0036323443 scopus 로고    scopus 로고
    • Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death
    • Cregan SP, Fortin A, MacLaurin JG, Callaghan SM, Cecconi F, et al. 2002. Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death. J Cell Biol 158:507-517.
    • (2002) J Cell Biol , vol.158 , pp. 507-517
    • Cregan, S.P.1    Fortin, A.2    MacLaurin, J.G.3    Callaghan, S.M.4    Cecconi, F.5
  • 81
    • 0033565557 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore and its role in cell death
    • Crompton M. 1999. The mitochondrial permeability transition pore and its role in cell death. Biochem J 341(Pt 2):233-249.
    • (1999) Biochem J , vol.341 , Issue.PART 2 , pp. 233-249
    • Crompton, M.1
  • 82
    • 0034668791 scopus 로고    scopus 로고
    • Mitochondrial intermembrane junctional complexes and their role in cell death
    • Crompton M. 2000. Mitochondrial intermembrane junctional complexes and their role in cell death. J Physiol 529 Pt (1): 11-21.
    • (2000) J Physiol , vol.529 , Issue.1 PART , pp. 11-21
    • Crompton, M.1
  • 83
    • 0042526700 scopus 로고    scopus 로고
    • On the involvement of mitochondrial intermembrane junctional complexes in apoptosis
    • Crompton M. 2003. On the involvement of mitochondrial intermembrane junctional complexes in apoptosis. Curr Med Chem 10:1473-1484.
    • (2003) Curr Med Chem , vol.10 , pp. 1473-1484
    • Crompton, M.1
  • 85
    • 0018068221 scopus 로고
    • The cycling of calcium, sodium, and protons across the inner membrane of cardiac mitochondria
    • Crompton M, Heid I. 1978. The cycling of calcium, sodium, and protons across the inner membrane of cardiac mitochondria. Eur J Biochem 91:599-608.
    • (1978) Eur J Biochem , vol.91 , pp. 599-608
    • Crompton, M.1    Heid, I.2
  • 86
    • 0036479049 scopus 로고    scopus 로고
    • Mitochondrial intermembrane junctional complexes and their involvement in cell death
    • Crompton M, Barksby E, Johnson N, Capano M. 2002. Mitochondrial intermembrane junctional complexes and their involvement in cell death. Biochimie 84:143-152.
    • (2002) Biochimie , vol.84 , pp. 143-152
    • Crompton, M.1    Barksby, E.2    Johnson, N.3    Capano, M.4
  • 87
    • 0023821864 scopus 로고
    • 2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress
    • 2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress. Biochem J 255:357-360.
    • (1988) Biochem J , vol.255 , pp. 357-360
    • Crompton, M.1    Ellinger, H.2    Costi, A.3
  • 88
    • 0017716659 scopus 로고
    • The calciuminduced and sodium-induced effluxes of calcium from heart mitochondria. Evidence for a sodium-calcium carrier
    • Crompton M, Kunzi M, Carafoli E. 1977. The calciuminduced and sodium-induced effluxes of calcium from heart mitochondria. Evidence for a sodium-calcium carrier. Eur J Biochem 79:549-558.
    • (1977) Eur J Biochem , vol.79 , pp. 549-558
    • Crompton, M.1    Kunzi, M.2    Carafoli, E.3
  • 90
    • 0032401567 scopus 로고    scopus 로고
    • Cyclophilin-D binds stronglytocomplexesofthe voltage-dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore
    • Crompton M, Virji S, Ward JM. 1998. Cyclophilin-D binds stronglytocomplexesofthe voltage-dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore. Eur J Biochem 258:729-735.
    • (1998) Eur J Biochem , vol.258 , pp. 729-735
    • Crompton, M.1    Virji, S.2    Ward, J.M.3
  • 92
    • 0027453536 scopus 로고
    • Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity
    • Dawson TM, Steiner JP, Dawson VL, Dinerman JL, Uhl GR, et al. 1993. Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity. Proc Natl Acad Sci USA 90:9808-9812.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9808-9812
    • Dawson, T.M.1    Steiner, J.P.2    Dawson, V.L.3    Dinerman, J.L.4    Uhl, G.R.5
  • 93
    • 0026547406 scopus 로고
    • Ultrastructural changes in the hippocampal CA1 region following transient cerebral ischemia: Evidence against programmed cell death
    • Deshpande J, Bergstedt K, Linden T, Kalimo H, Wieloch T. 1992. Ultrastructural changes in the hippocampal CA1 region following transient cerebral ischemia: Evidence against programmed cell death. Exp Brain Res 88:91-105.
    • (1992) Exp Brain Res , vol.88 , pp. 91-105
    • Deshpande, J.1    Bergstedt, K.2    Linden, T.3    Kalimo, H.4    Wieloch, T.5
  • 94
    • 31444442215 scopus 로고    scopus 로고
    • Arachidonic acid induces specific membrane permeability increase in heart mitochondria
    • Di Paola M, Zaccagnino P, Oliveros-Celis C, Lorusso M. 2006. Arachidonic acid induces specific membrane permeability increase in heart mitochondria. FEBS Lett 580:775-781.
    • (2006) FEBS Lett , vol.580 , pp. 775-781
    • Di Paola, M.1    Zaccagnino, P.2    Oliveros-Celis, C.3    Lorusso, M.4
  • 95
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischemic stroke: An integrated view
    • Dirnagl U, Iadecola C, Moskowitz MA. 1999. Pathobiology of ischemic stroke: An integrated view. Trends Neurosci 22:391-397.
    • (1999) Trends Neurosci , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 96
    • 0038381490 scopus 로고    scopus 로고
    • Inhibition of the mitochondrial permeability transition by creatine kinase substrates. Requirement for microcompartmentation
    • Dolder M, Walzel B, Speer O, Schlattner U, Wallimann T. 2003. Inhibition of the mitochondrial permeability transition by creatine kinase substrates. Requirement for microcompartmentation. J Biol Chem 278:17760-17766.
    • (2003) J Biol Chem , vol.278 , pp. 17760-17766
    • Dolder, M.1    Walzel, B.2    Speer, O.3    Schlattner, U.4    Wallimann, T.5
  • 97
    • 0035107677 scopus 로고    scopus 로고
    • Mitochondrial creatine kinase in contact sites: Interaction with porin and adenine nucleotide translocase, role in permeability transition, and sensitivity to oxidative damage
    • Dolder M, Wendt S, Wallimann T. 2001. Mitochondrial creatine kinase in contact sites: Interaction with porin and adenine nucleotide translocase, role in permeability transition, and sensitivity to oxidative damage. Biol Signal Recept 10:93-111.
    • (2001) Biol Signal Recept , vol.10 , pp. 93-111
    • Dolder, M.1    Wendt, S.2    Wallimann, T.3
  • 98
    • 24144458255 scopus 로고    scopus 로고
    • CNS mitochondria in neurodegenerative disorders
    • Dubinsky JM. 2005. CNS mitochondria in neurodegenerative disorders. Antioxid Redox Signal 7:1089-1091.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 1089-1091
    • Dubinsky, J.M.1
  • 99
    • 0032530326 scopus 로고    scopus 로고
    • Calcium-induced activation of the mitochondrial permeability transition in hippocampal neurons
    • Dubinsky JM, Levi Y. 1998. Calcium-induced activation of the mitochondrial permeability transition in hippocampal neurons. J Neurosci Res 53:728-741.
    • (1998) J Neurosci Res , vol.53 , pp. 728-741
    • Dubinsky, J.M.1    Levi, Y.2
  • 100
    • 0027381281 scopus 로고
    • On the involvement of a cyclosporin A-sensitive mitochondrial pore in myocardial reperfusion injury
    • Duchen MR, McGuinness O, Brown LA, Crompton M. 1993. On the involvement of a cyclosporin A-sensitive mitochondrial pore in myocardial reperfusion injury. Cardiovasc Res 27:1790-1794.
    • (1993) Cardiovasc Res , vol.27 , pp. 1790-1794
    • Duchen, M.R.1    McGuinness, O.2    Brown, L.A.3    Crompton, M.4
  • 101
    • 10244246628 scopus 로고    scopus 로고
    • Astrocyte mitochondria in in vitro models of ischemia
    • Dugan LL, Kim-Han JS. 2004. Astrocyte mitochondria in in vitro models of ischemia. J Bioenerg Biomembr 36:317-321.
    • (2004) J Bioenerg Biomembr , vol.36 , pp. 317-321
    • Dugan, L.L.1    Kim-Han, J.S.2
  • 103
    • 0031892704 scopus 로고    scopus 로고
    • Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family
    • Endres M, Namura S, Shimizu-Sasamata M, Waeber C, Zhang L, et al. 1998. Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family. J Cereb Blood Flow Metab 18:238-247.
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 238-247
    • Endres, M.1    Namura, S.2    Shimizu-Sasamata, M.3    Waeber, C.4    Zhang, L.5
  • 105
    • 0030615284 scopus 로고    scopus 로고
    • The phospholipase A2 inhibitor, quinacrine, reduces infarct size in rats after transient middle cerebral artery occlusion
    • Estevez AY, Phillis JW. 1997. The phospholipase A2 inhibitor, quinacrine, reduces infarct size in rats after transient middle cerebral artery occlusion. Brain Res 752:203-208.
    • (1997) Brain Res , vol.752 , pp. 203-208
    • Estevez, A.Y.1    Phillis, J.W.2
  • 107
    • 2442609694 scopus 로고    scopus 로고
    • Mobilization of adenine nucleotide translocators as molecular bases of the biochemical threshold effect observed in mitochondrial diseases
    • Faustin B, Rossignol R, Rocher C, Benard G, Malgat M, et al. 2004. Mobilization of adenine nucleotide translocators as molecular bases of the biochemical threshold effect observed in mitochondrial diseases. J Biol Chem 279:20411-20421.
    • (2004) J Biol Chem , vol.279 , pp. 20411-20421
    • Faustin, B.1    Rossignol, R.2    Rocher, C.3    Benard, G.4    Malgat, M.5
  • 108
    • 20444483258 scopus 로고    scopus 로고
    • Involvement of mitochondrial potential and calcium buffering capacity in minocycline cytoprotective actions
    • Fernandez-Gomez FJ, Galindo MF, Gomez-Lazaro M, Gonzalez-Garcia C, Cena V, et al. 2005. Involvement of mitochondrial potential and calcium buffering capacity in minocycline cytoprotective actions. Neuroscience 133:959-967.
    • (2005) Neuroscience , vol.133 , pp. 959-967
    • Fernandez-Gomez, F.J.1    Galindo, M.F.2    Gomez-Lazaro, M.3    Gonzalez-Garcia, C.4    Cena, V.5
  • 109
    • 10744231655 scopus 로고    scopus 로고
    • Cyclosporin A prevents calpain activation despite increased intracellular calcium concentrations, as well as translocation of apoptosis-inducing factor, cytochrome c, and caspase-3 activation in neurons exposed to transient hypoglycemia
    • Ferrand-Drake M, Zhu C, Gido G, Hansen AJ, Karlsson JO, et al. 2003. Cyclosporin A prevents calpain activation despite increased intracellular calcium concentrations, as well as translocation of apoptosis-inducing factor, cytochrome c, and caspase-3 activation in neurons exposed to transient hypoglycemia. J Neurochem 85:1431-1442.
    • (2003) J Neurochem , vol.85 , pp. 1431-1442
    • Ferrand-Drake, M.1    Zhu, C.2    Gido, G.3    Hansen, A.J.4    Karlsson, J.O.5
  • 110
    • 0031718374 scopus 로고    scopus 로고
    • Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation
    • Fink K, Zhu J, Namura S, Shimizu-Sasamata M, Endres M, et al. 1998. Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation. J Cereb Blood Flow Metab 18:1071-1076.
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 1071-1076
    • Fink, K.1    Zhu, J.2    Namura, S.3    Shimizu-Sasamata, M.4    Endres, M.5
  • 111
    • 0032524667 scopus 로고    scopus 로고
    • Regulation of the permeability transition pore in skeletal muscle mitochondria. Modulation by electron flow through the respiratory chain complex I
    • Fontaine E, Eriksson O, Ichas F, Bernardi P. 1998a. Regulation of the permeability transition pore in skeletal muscle mitochondria. Modulation by electron flow through the respiratory chain complex I. J Biol Chem 273:12662-12668.
    • (1998) J Biol Chem , vol.273 , pp. 12662-12668
    • Fontaine, E.1    Eriksson, O.2    Ichas, F.3    Bernardi, P.4
  • 112
    • 0032475979 scopus 로고    scopus 로고
    • A ubiquinone-binding site regulates the mitochondrial permeability transition pore
    • Fontaine E, Ichas F, Bernardi P. 1998b. A ubiquinone-binding site regulates the mitochondrial permeability transition pore. J Biol Chem 273:25734-25740.
    • (1998) J Biol Chem , vol.273 , pp. 25734-25740
    • Fontaine, E.1    Ichas, F.2    Bernardi, P.3
  • 113
    • 0023263612 scopus 로고
    • Action of cyclosporin on mitochondrial calcium fluxes
    • Fournier N, Ducet G, Crevat A. 1987. Action of cyclosporin on mitochondrial calcium fluxes. J Bioenerg Biomembr 19:297-303.
    • (1987) J Bioenerg Biomembr , vol.19 , pp. 297-303
    • Fournier, N.1    Ducet, G.2    Crevat, A.3
  • 114
    • 0033007651 scopus 로고    scopus 로고
    • Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability
    • Friberg H, Connern C, Halestrap AP, Wieloch T. 1999. Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability. J Neurochem 72:2488-2497.
    • (1999) J Neurochem , vol.72 , pp. 2488-2497
    • Friberg, H.1    Connern, C.2    Halestrap, A.P.3    Wieloch, T.4
  • 115
    • 0032528154 scopus 로고    scopus 로고
    • Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death
    • Friberg H, Ferrand-Drake M, Bengtsson F, Halestrap AP, Wieloch T. 1998. Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death. J Neurosci 18:5151-5159.
    • (1998) J Neurosci , vol.18 , pp. 5151-5159
    • Friberg, H.1    Ferrand-Drake, M.2    Bengtsson, F.3    Halestrap, A.P.4    Wieloch, T.5
  • 116
    • 27744553138 scopus 로고    scopus 로고
    • In vitro properties of 5-(benzylsulfonyl)-4-bromo-2-methyl-3 (2H)-pyridazinone: A novel permeability transition pore inhibitor
    • Fuks B, Talaga P, Huart C, Henichart JP, Bertrand K, et al. 2005. In vitro properties of 5-(benzylsulfonyl)-4-bromo-2-methyl-3 (2H)-pyridazinone: A novel permeability transition pore inhibitor. Eur J Pharmacol 519:24-30.
    • (2005) Eur J Pharmacol , vol.519 , pp. 24-30
    • Fuks, B.1    Talaga, P.2    Huart, C.3    Henichart, J.P.4    Bertrand, K.5
  • 117
    • 33646375707 scopus 로고    scopus 로고
    • Mitochondrial iPLA2 activity modulates the release of cytochrome c from mitochondria and influences the permeability transition
    • Gadd ME, Broekemeier KM, Crouser ED, Kumar J, Graff G, et al. 2006. Mitochondrial iPLA2 activity modulates the release of cytochrome c from mitochondria and influences the permeability transition. J Biol Chem 281:6931-6939.
    • (2006) J Biol Chem , vol.281 , pp. 6931-6939
    • Gadd, M.E.1    Broekemeier, K.M.2    Crouser, E.D.3    Kumar, J.4    Graff, G.5
  • 118
    • 0031571757 scopus 로고    scopus 로고
    • 2+-independent permeabilization of the inner mitochondrial membrane by peroxynitrite is mediated by membrane protein thiol cross-linking and lipid peroxidation
    • 2+-independent permeabilization of the inner mitochondrial membrane by peroxynitrite is mediated by membrane protein thiol cross-linking and lipid peroxidation. Arch Biochem Biophys 345:243-250.
    • (1997) Arch Biochem Biophys , vol.345 , pp. 243-250
    • Gadelha, F.R.1    Thomson, L.2    Fagian, M.M.3    Costa, A.D.4    Radi, R.5
  • 120
    • 0035985936 scopus 로고    scopus 로고
    • Mitochondrial permeability transition can be directly monitored in living neurons
    • Gillessen T, Grasshoff C, Szinicz L. 2002. Mitochondrial permeability transition can be directly monitored in living neurons. Biomed Pharmacother 56:186-193.
    • (2002) Biomed Pharmacother , vol.56 , pp. 186-193
    • Gillessen, T.1    Grasshoff, C.2    Szinicz, L.3
  • 121
    • 3543151336 scopus 로고    scopus 로고
    • Glutamate interacts with VDAC and modulates opening of the mitochondrial permeability transition pore
    • Gincel D, Shoshan-Barmatz V. 2004. Glutamate interacts with VDAC and modulates opening of the mitochondrial permeability transition pore. J Bioenerg Biomembr 36:179-186.
    • (2004) J Bioenerg Biomembr , vol.36 , pp. 179-186
    • Gincel, D.1    Shoshan-Barmatz, V.2
  • 122
    • 0035881510 scopus 로고    scopus 로고
    • Calcium binding and translocation by the voltage-dependent anion channel: A possible regulatory mechanism in mitochondrial function
    • Gincel D, Zaid H, Shoshan-Barmatz V. 2001. Calcium binding and translocation by the voltage-dependent anion channel: A possible regulatory mechanism in mitochondrial function. Biochem J 358:147-155.
    • (2001) Biochem J , vol.358 , pp. 147-155
    • Gincel, D.1    Zaid, H.2    Shoshan-Barmatz, V.3
  • 123
    • 0342602044 scopus 로고    scopus 로고
    • Deletion of amino acids 261-269 in the brown fat uncoupling protein converts the carrier into a pore
    • Gonzalez-Barroso MM, Fleury C, Levi-Meyrueis C, Zaragoza P, Bouillaud F, et al. 1997. Deletion of amino acids 261-269 in the brown fat uncoupling protein converts the carrier into a pore. Biochemistry 36:10930-10935.
    • (1997) Biochemistry , vol.36 , pp. 10930-10935
    • Gonzalez-Barroso, M.M.1    Fleury, C.2    Levi-Meyrueis, C.3    Zaragoza, P.4    Bouillaud, F.5
  • 124
    • 20044370709 scopus 로고    scopus 로고
    • Bid interaction with cardiolipin primarily orchestrates mitochondrial dysfunctions and subsequently activates Bax and Bak
    • Gonzalvez F, Pariselli F, Dupaigne P, Budihardjo I, Lutter M., et al. 2005. tBid interaction with cardiolipin primarily orchestrates mitochondrial dysfunctions and subsequently activates Bax and Bak. Cell Death Differ 12:614-626.
    • (2005) Cell Death Differ , vol.12 , pp. 614-626
    • Gonzalvez, F.1    Pariselli, F.2    Dupaigne, P.3    Budihardjo, I.4    Lutter, M.5
  • 125
    • 0034983918 scopus 로고    scopus 로고
    • Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase
    • Gottlob K, Majewski N, Kennedy S, Kandel E, Robey RB, et al. 2001. Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. Genes Dev 15:1406-1418.
    • (2001) Genes Dev , vol.15 , pp. 1406-1418
    • Gottlob, K.1    Majewski, N.2    Kennedy, S.3    Kandel, E.4    Robey, R.B.5
  • 126
    • 3442886811 scopus 로고    scopus 로고
    • The pathophysiology of mitochondrial cell death
    • Green DR, Kroemer G. 2004. The pathophysiology of mitochondrial cell death. Science 305:626-629.
    • (2004) Science , vol.305 , pp. 626-629
    • Green, D.R.1    Kroemer, G.2
  • 127
    • 0028968606 scopus 로고
    • Mitochondrial nonspecific pores remain closed during cardiac ischemia, but open upon reperfusion
    • Griffiths EJ, Halestrap AP. 1995. Mitochondrial nonspecific pores remain closed during cardiac ischemia, but open upon reperfusion. Biochem J 307(Pt 1):93-98.
    • (1995) Biochem J , vol.307 , Issue.PART 1 , pp. 93-98
    • Griffiths, E.J.1    Halestrap, A.P.2
  • 128
    • 0032589515 scopus 로고    scopus 로고
    • 2+-stimulated generation of reactive oxygen species by the respiratory chain
    • 2+-stimulated generation of reactive oxygen species by the respiratory chain. Biochemistry 38:13279-13287.
    • (1999) Biochemistry , vol.38 , pp. 13279-13287
    • Grijalba, M.T.1    Vercesi, A.E.2    Schreier, S.3
  • 129
    • 0025292743 scopus 로고
    • Mechanisms by which mitochondria transport calcium
    • Gunter TE, Pfeiffer DR. 1990. Mechanisms by which mitochondria transport calcium. Am J Physiol 258:C755-C786.
    • (1990) Am J Physiol , vol.258
    • Gunter, T.E.1    Pfeiffer, D.R.2
  • 130
    • 15844404722 scopus 로고    scopus 로고
    • Biochemistry: A pore way to die
    • Halestrap A. 2005. Biochemistry: A pore way to die. Nature 434:578-579.
    • (2005) Nature , vol.434 , pp. 578-579
    • Halestrap, A.1
  • 131
    • 0025769501 scopus 로고
    • Calcium-dependent opening of a nonspecific pore in the mitochondrial inner membrane is inhibited at pH values below 7. Implications for the protective effect of low pH against chemical and hypoxic cell damage
    • Halestrap AP. 1991. Calcium-dependent opening of a nonspecific pore in the mitochondrial inner membrane is inhibited at pH values below 7. Implications for the protective effect of low pH against chemical and hypoxic cell damage. Biochem J 278(Pt 3):715-719.
    • (1991) Biochem J , vol.278 , Issue.PART 3 , pp. 715-719
    • Halestrap, A.P.1
  • 132
    • 0033290850 scopus 로고    scopus 로고
    • The mitochondrial permeability transition: Its molecular mechanism and role in reperfusion injury
    • Halestrap AP. 1999. The mitochondrial permeability transition: Its molecular mechanism and role in reperfusion injury. Biochem Soc Symp 66:181-203.
    • (1999) Biochem Soc Symp , vol.66 , pp. 181-203
    • Halestrap, A.P.1
  • 133
    • 4344707798 scopus 로고    scopus 로고
    • Mitochondrial permeability: Dual role for the ADP/ATP translocator?
    • Brief communication
    • Halestrap AP. 2004. Mitochondrial permeability: Dual role for the ADP/ATP translocator? Nature 430. Brief communication.
    • (2004) Nature , pp. 430
    • Halestrap, A.P.1
  • 134
    • 33645994183 scopus 로고    scopus 로고
    • Calcium, mitochondria, and reperfusion injury: A pore way to die
    • Halestrap AP. 2006. Calcium, mitochondria, and reperfusion injury: A pore way to die. Biochem Soc Trans 34:232-237.
    • (2006) Biochem Soc Trans , vol.34 , pp. 232-237
    • Halestrap, A.P.1
  • 135
    • 0041810128 scopus 로고    scopus 로고
    • The adenine nucleotide translocase: A central component of the mitochondrial permeability transition pore and key player in cell death
    • Halestrap AP, Brennerb C. 2003. The adenine nucleotide translocase: A central component of the mitochondrial permeability transition pore and key player in cell death. Curr Med Chem 10:1507-1525.
    • (2003) Curr Med Chem , vol.10 , pp. 1507-1525
    • Halestrap, A.P.1    Brennerb, C.2
  • 136
    • 0025193488 scopus 로고
    • 2+-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adenine nucleotide translocase
    • 2+-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adenine nucleotide translocase. Biochem J 268:153-160.
    • (1990) Biochem J , vol.268 , pp. 153-160
    • Halestrap, A.P.1    Davidson, A.M.2
  • 137
    • 0030826778 scopus 로고    scopus 로고
    • Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischemia/reperfusion injury
    • Halestrap AP, Connern CP, Griffiths EJ, Kerr PM. 1997a. Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischemia/reperfusion injury. Mol Cell Biochem 174:167-172.
    • (1997) Mol Cell Biochem , vol.174 , pp. 167-172
    • Halestrap, A.P.1    Connern, C.P.2    Griffiths, E.J.3    Kerr, P.M.4
  • 138
    • 0031013623 scopus 로고    scopus 로고
    • Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase
    • Halestrap AP, Woodfield KY, Connern CP. 1997b. Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase. J Biol Chem 272:3346-3354.
    • (1997) J Biol Chem , vol.272 , pp. 3346-3354
    • Halestrap, A.P.1    Woodfield, K.Y.2    Connern, C.P.3
  • 140
    • 0032504709 scopus 로고    scopus 로고
    • Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart
    • Halestrap AP, Kerr PM, Javadov S, Woodfield KY. 1998. Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart. Biochim Biophys Acta 1366:79-94.
    • (1998) Biochim Biophys Acta , vol.1366 , pp. 79-94
    • Halestrap, A.P.1    Kerr, P.M.2    Javadov, S.3    Woodfield, K.Y.4
  • 141
    • 2042520908 scopus 로고    scopus 로고
    • Brain-derived respiring mitochondria exhibit homogeneous, complete, and cyclosporin-sensitive permeability transition
    • Hansson MJ, Mansson R, Mattiasson G, Ohlsson J, Karlsson J, et al. 2004a. Brain-derived respiring mitochondria exhibit homogeneous, complete, and cyclosporin-sensitive permeability transition. J Neurochem 89:715-729.
    • (2004) J Neurochem , vol.89 , pp. 715-729
    • Hansson, M.J.1    Mansson, R.2    Mattiasson, G.3    Ohlsson, J.4    Karlsson, J.5
  • 142
    • 10244236553 scopus 로고    scopus 로고
    • The nonimmunosuppressive cyclosporin analogs NIM811 and UNIL025 display nanomolar potencies on permeability transition in brain-derived mitochondria
    • Hansson MJ, Mattiasson G, Mansson R, Karlsson J, Keep MF, et al. 2004b. The nonimmunosuppressive cyclosporin analogs NIM811 and UNIL025 display nanomolar potencies on permeability transition in brain-derived mitochondria. J Bioenerg Biomembr 36:407-413.
    • (2004) J Bioenerg Biomembr , vol.36 , pp. 407-413
    • Hansson, M.J.1    Mattiasson, G.2    Mansson, R.3    Karlsson, J.4    Keep, M.F.5
  • 143
    • 0037449449 scopus 로고    scopus 로고
    • Powerful cyclosporin inhibition of calcium-induced permeability transition in brain mitochondria
    • Hansson MJ, Persson T, Friberg H, Keep MF, Rees A, et al. 2003. Powerful cyclosporin inhibition of calcium-induced permeability transition in brain mitochondria. Brain Res 960:99-111.
    • (2003) Brain Res , vol.960 , pp. 99-111
    • Hansson, M.J.1    Persson, T.2    Friberg, H.3    Keep, M.F.4    Rees, A.5
  • 145
    • 0019230323 scopus 로고
    • 2+-activated hydrophilic channel of the mitochondrial inner membrane by nucleotides
    • 2+-activated hydrophilic channel of the mitochondrial inner membrane by nucleotides. J Membr Biol 54:231-236.
    • (1980) J Membr Biol , vol.54 , pp. 231-236
    • Haworth, R.A.1    Hunter, D.R.2
  • 146
    • 0037070178 scopus 로고    scopus 로고
    • Regulated and unregulated mitochondrial permeability transition pores: A new paradigm of pore structure and function?
    • He L, Lemasters JJ. 2002. Regulated and unregulated mitochondrial permeability transition pores: A new paradigm of pore structure and function? FEBS Lett 512:1-7.
    • (2002) FEBS Lett , vol.512 , pp. 1-7
    • He, L.1    Lemasters, J.J.2
  • 147
    • 0028084988 scopus 로고
    • The reconstituted ADP/ATP carrier activity has an absolute requirement for cardiolipin as shown in cysteine mutants
    • Hoffmann B, Stockl A, Schlame M, Beyer K, Klingenberg M. 1994. The reconstituted ADP/ATP carrier activity has an absolute requirement for cardiolipin as shown in cysteine mutants. J Biol Chem 269:1940-1944.
    • (1994) J Biol Chem , vol.269 , pp. 1940-1944
    • Hoffmann, B.1    Stockl, A.2    Schlame, M.3    Beyer, K.4    Klingenberg, M.5
  • 148
    • 0030729437 scopus 로고    scopus 로고
    • Trifluoperazine- and dibucaine-induced inhibition of glutamate-induced mitochondrial depolarization in rat cultured forebrain neurons
    • Hoyt KR, Sharma TA, Reynolds IJ. 1997. Trifluoperazine- and dibucaine-induced inhibition of glutamate-induced mitochondrial depolarization in rat cultured forebrain neurons. Br J Pharmacol 122:803-808.
    • (1997) Br J Pharmacol , vol.122 , pp. 803-808
    • Hoyt, K.R.1    Sharma, T.A.2    Reynolds, I.J.3
  • 149
    • 0033848718 scopus 로고    scopus 로고
    • Involvement of caspase-3 in cell death after hypoxia-ischemia declines during brain maturation
    • Hu BR, Liu CL, Ouyang Y, Blomgren K, Siesjo BK. 2000. Involvement of caspase-3 in cell death after hypoxia-ischemia declines during brain maturation. J Cereb Blood Flow Metab 20:1294-1300.
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 1294-1300
    • Hu, B.R.1    Liu, C.L.2    Ouyang, Y.3    Blomgren, K.4    Siesjo, B.K.5
  • 150
    • 0141481850 scopus 로고    scopus 로고
    • Inhibition of a-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death
    • Huang HM, Ou HC, Xu H, Chen HL, Fowler C, et al. 2003. Inhibition of a-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death. J Neurosci Res 74:309-317.
    • (2003) J Neurosci Res , vol.74 , pp. 309-317
    • Huang, H.M.1    Ou, H.C.2    Xu, H.3    Chen, H.L.4    Fowler, C.5
  • 151
    • 0017089948 scopus 로고
    • Relationship between configuration, function, and permeability in calcium-treated mitochondria
    • Hunter DR, Haworth RA, Southard JH. 1976. Relationship between configuration, function, and permeability in calcium-treated mitochondria. J Biol Chem 251:5069-5077.
    • (1976) J Biol Chem , vol.251 , pp. 5069-5077
    • Hunter, D.R.1    Haworth, R.A.2    Southard, J.H.3
  • 153
    • 0018332596 scopus 로고
    • 2+-induced membrane transition in mitochondria. I. The protective mechanisms
    • 2+-induced membrane transition in mitochondria. I. The protective mechanisms. Arch Biochem Biophys 195:453-459.
    • (1979) Arch Biochem Biophys , vol.195 , pp. 453-459
    • Hunter, D.R.1    Haworth, R.A.2
  • 154
    • 0343123179 scopus 로고
    • Inactivation of oxidative and phosphorylative systems in mitochondria by preincubation with phosphate and other ions
    • Hunter FE Jr, Ford L. 1955. Inactivation of oxidative and phosphorylative systems in mitochondria by preincubation with phosphate and other ions. J Biol Chem 216:357-369.
    • (1955) J Biol Chem , vol.216 , pp. 357-369
    • Hunter Jr., F.E.1    Ford, L.2
  • 155
    • 0037745119 scopus 로고    scopus 로고
    • Fluctuations in mitochondrial membrane potential caused by repetitive gating of the permeability transition pore
    • Huser J, Blatter LA. 1999. Fluctuations in mitochondrial membrane potential caused by repetitive gating of the permeability transition pore. Biochem J 343 Pt (2): 311-317.
    • (1999) Biochem J , vol.343 , Issue.2 PART , pp. 311-317
    • Huser, J.1    Blatter, L.A.2
  • 156
    • 0032504717 scopus 로고    scopus 로고
    • From calcium signaling to cell death: Two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state
    • Ichas F, Mazat JP. 1998. From calcium signaling to cell death: Two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state. Biochim Biophys Acta 1366:33-50.
    • (1998) Biochim Biophys Acta , vol.1366 , pp. 33-50
    • Ichas, F.1    Mazat, J.P.2
  • 157
    • 0031587822 scopus 로고    scopus 로고
    • Mitochondria are excitable organelles capable of generating and conveying electrical and calcium signals
    • Ichas F, Jouaville LS, Mazat JP. 1997. Mitochondria are excitable organelles capable of generating and conveying electrical and calcium signals. Cell 89:1145-1153.
    • (1997) Cell , vol.89 , pp. 1145-1153
    • Ichas, F.1    Jouaville, L.S.2    Mazat, J.P.3
  • 158
    • 0026492417 scopus 로고
    • Synergism of cyclosporin A and phospholipase inhibitors in protection against lethal injury to rat hepatocytes from oxidant chemicals
    • Imberti R, Nieminen AL, Herman B, Lemasters JJ. 1992. Synergism of cyclosporin A and phospholipase inhibitors in protection against lethal injury to rat hepatocytes from oxidant chemicals. Res Commun Chem Path 78:27-38.
    • (1992) Res Commun Chem Path , vol.78 , pp. 27-38
    • Imberti, R.1    Nieminen, A.L.2    Herman, B.3    Lemasters, J.J.4
  • 160
    • 24144495250 scopus 로고    scopus 로고
    • Cytochrome c release from CNS mitochondria and potential for clinical intervention in apoptosis-mediated CNS diseases
    • Jemmerson R, Dubinsky JM, Brustovetsky N. 2005. Cytochrome c release from CNS mitochondria and potential for clinical intervention in apoptosis-mediated CNS diseases. Antioxid Redox Signal 7:1158-1172.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 1158-1172
    • Jemmerson, R.1    Dubinsky, J.M.2    Brustovetsky, N.3
  • 161
    • 20144389194 scopus 로고    scopus 로고
    • Modification of permeability transition pore arginine (s) by phenylglyoxal derivatives in isolated mitochondria and mammalian cells. Structure-function relationship of arginine ligands
    • Johans M, Milanesi E, Franck M, Johans C, Liobikas J, et al. 2005. Modification of permeability transition pore arginine (s) by phenylglyoxal derivatives in isolated mitochondria and mammalian cells. Structure-function relationship of arginine ligands. J Biol Chem 280:12130-12136.
    • (2005) J Biol Chem , vol.280 , pp. 12130-12136
    • Johans, M.1    Milanesi, E.2    Franck, M.3    Johans, C.4    Liobikas, J.5
  • 162
    • 17644383671 scopus 로고    scopus 로고
    • Evidence in favour of a role for peripheral-type benzodiazepine receptor ligands in amplification of neuronal apoptosis
    • Jorda EG, Jimenez A, Verdaguer E, Canudas AM, Folch J, et al. 2005. Evidence in favour of a role for peripheral-type benzodiazepine receptor ligands in amplification of neuronal apoptosis. Apoptosis 10:91-104.
    • (2005) Apoptosis , vol.10 , pp. 91-104
    • Jorda, E.G.1    Jimenez, A.2    Verdaguer, E.3    Canudas, A.M.4    Folch, J.5
  • 163
    • 0025194251 scopus 로고
    • 2+ changes with metabolic state in isolated heart mitochondria
    • 2+ changes with metabolic state in isolated heart mitochondria. Biochemistry 29:4121-4128.
    • (1990) Biochemistry , vol.29 , pp. 4121-4128
    • Jung, D.W.1    Apel, L.2    Brierley, G.P.3
  • 164
    • 0026456627 scopus 로고
    • Effects of ketanserin and mianserin on delayed neuronal death induced by cerebral ischemia in Mongolian gerbils
    • Karasawa Y, Araki H, Otomo S. 1992. Effects of ketanserin and mianserin on delayed neuronal death induced by cerebral ischemia in Mongolian gerbils. Psychopharmacology (Berl) 109:264-270.
    • (1992) Psychopharmacology (Berl) , vol.109 , pp. 264-270
    • Karasawa, Y.1    Araki, H.2    Otomo, S.3
  • 165
    • 3042511616 scopus 로고    scopus 로고
    • Life span extension and reduced neuronal death after weekly intraventricular cyclosporin injections in the G93A transgenic mouse model of amyotrophic lateral sclerosis
    • Karlsson J, Fong KS, Hansson MJ, Elmer E, Csiszar K, et al. 2004. Life span extension and reduced neuronal death after weekly intraventricular cyclosporin injections in the G93A transgenic mouse model of amyotrophic lateral sclerosis. J Neurosurg 101:128-137.
    • (2004) J Neurosurg , vol.101 , pp. 128-137
    • Karlsson, J.1    Fong, K.S.2    Hansson, M.J.3    Elmer, E.4    Csiszar, K.5
  • 167
    • 0035896440 scopus 로고    scopus 로고
    • Intrathecal cyclosporin prolongs survival of late-stage ALS mice
    • Keep M, Elmer E, Fong KS, Csiszar K. 2001. Intrathecal cyclosporin prolongs survival of late-stage ALS mice. Brain Res 894:327-331.
    • (2001) Brain Res , vol.894 , pp. 327-331
    • Keep, M.1    Elmer, E.2    Fong, K.S.3    Csiszar, K.4
  • 168
    • 0032860116 scopus 로고    scopus 로고
    • Cyclosporin A and its nonimmunosuppressive analog N-Me-Va l-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons
    • Khaspekov L, Friberg H, Halestrap A, Viktorov I, Wieloch T. 1999. Cyclosporin A and its nonimmunosuppressive analog N-Me-Va l-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons. Eur J Neurosci 11:3194-3198.
    • (1999) Eur J Neurosci , vol.11 , pp. 3194-3198
    • Khaspekov, L.1    Friberg, H.2    Halestrap, A.3    Viktorov, I.4    Wieloch, T.5
  • 169
    • 0037427440 scopus 로고    scopus 로고
    • Mitochondrial permeability transition: A common pathway to necrosis and apoptosis
    • Kim JS, He L, Lemasters JJ. 2003. Mitochondrial permeability transition: A common pathway to necrosis and apoptosis. Biochem Biophys Res Commun 304:463-470.
    • (2003) Biochem Biophys Res Commun , vol.304 , pp. 463-470
    • Kim, J.S.1    He, L.2    Lemasters, J.J.3
  • 170
    • 0034698952 scopus 로고    scopus 로고
    • Acute treatment with tamoxifen reduces ischemic damage following middle cerebral artery occlusion
    • Kimelberg HK, Feustel PJ, Jin Y, Paquette J, Boulos A, et al. 2000. Acute treatment with tamoxifen reduces ischemic damage following middle cerebral artery occlusion. Neuroreport 11:2675-2679.
    • (2000) Neuroreport , vol.11 , pp. 2675-2679
    • Kimelberg, H.K.1    Feustel, P.J.2    Jin, Y.3    Paquette, J.4    Boulos, A.5
  • 171
    • 0024433994 scopus 로고
    • Mitochondrial channel activity studied by patch-clamping mitoplasts
    • Kinnally KW, Campo ML, Tedeschi H. 1989. Mitochondrial channel activity studied by patch-clamping mitoplasts. J Bioenerg Biomembr 21:497-506.
    • (1989) J Bioenerg Biomembr , vol.21 , pp. 497-506
    • Kinnally, K.W.1    Campo, M.L.2    Tedeschi, H.3
  • 172
    • 0027411220 scopus 로고
    • Mitochondrial benzodiazepine receptor linked to inner membrane ion channels by nanomolar actions of ligands
    • Kinnally KW, Zorov DB, Antonenko YN, Snyder SH, McEnery MW, et al. 1993. Mitochondrial benzodiazepine receptor linked to inner membrane ion channels by nanomolar actions of ligands. Proc Natl Acad Sci USA 90:1374-1378.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1374-1378
    • Kinnally, K.W.1    Zorov, D.B.2    Antonenko, Y.N.3    Snyder, S.H.4    McEnery, M.W.5
  • 173
    • 1842471937 scopus 로고    scopus 로고
    • Neuroprotective mechanisms of creatine occur in the absence of mitochondrial creatine kinase
    • Klivenyi P, Calingasan NY, Starkov A, Stavrovskaya IG, Kristal BS, et al. 2004. Neuroprotective mechanisms of creatine occur in the absence of mitochondrial creatine kinase. Neurobiol Dis 15:610-617.
    • (2004) Neurobiol Dis , vol.15 , pp. 610-617
    • Klivenyi, P.1    Calingasan, N.Y.2    Starkov, A.3    Stavrovskaya, I.G.4    Kristal, B.S.5
  • 174
    • 0033051815 scopus 로고    scopus 로고
    • Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis
    • Klivenyi P, Ferrante RJ, Matthews RT, Bogdanov MB, Klein AM, et al. 1999. Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis. Nat Med 5:347-350.
    • (1999) Nat Med , vol.5 , pp. 347-350
    • Klivenyi, P.1    Ferrante, R.J.2    Matthews, R.T.3    Bogdanov, M.B.4    Klein, A.M.5
  • 175
    • 0021111174 scopus 로고
    • Changes in freeze-fractured mitochondrial membranes correlated to their energetic state. Dynamic interactions of the boundary membranes
    • Knoll G, Brdiczka D. 1983. Changes in freeze-fractured mitochondrial membranes correlated to their energetic state. Dynamic interactions of the boundary membranes. Biochim Biophys Acta 733:102-110.
    • (1983) Biochim Biophys Acta , vol.733 , pp. 102-110
    • Knoll, G.1    Brdiczka, D.2
  • 176
    • 0037449421 scopus 로고    scopus 로고
    • Calcium-induced mitochondrial swelling and cytochrome c release in the brain: Its biochemical characteristics and implication in ischemic neuronal injury
    • Kobayashi T, Kuroda S, Tada M, Houkin K, Iwasaki Y, et al. 2003. Calcium-induced mitochondrial swelling and cytochrome c release in the brain: Its biochemical characteristics and implication in ischemic neuronal injury. Brain Res 960:62-70.
    • (2003) Brain Res , vol.960 , pp. 62-70
    • Kobayashi, T.1    Kuroda, S.2    Tada, M.3    Houkin, K.4    Iwasaki, Y.5
  • 177
    • 0842307483 scopus 로고    scopus 로고
    • The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore
    • Kokoszka JE, Waymire KG, Levy SE, Sligh JE, Cai J, et al. 2004. The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore. Nature 427:461-465.
    • (2004) Nature , vol.427 , pp. 461-465
    • Kokoszka, J.E.1    Waymire, K.G.2    Levy, S.E.3    Sligh, J.E.4    Cai, J.5
  • 179
    • 0035917814 scopus 로고    scopus 로고
    • Mitochondrial permeability transition and oxidative stress
    • Kowaltowski AJ, Castilho RF, Vercesi AE. 2001. Mitochondrial permeability transition and oxidative stress. FEBS Lett 495:12-15.
    • (2001) FEBS Lett , vol.495 , pp. 12-15
    • Kowaltowski, A.J.1    Castilho, R.F.2    Vercesi, A.E.3
  • 181
    • 0030800033 scopus 로고    scopus 로고
    • Mitochondrial permeability transition in the central nervous system: Induction by calcium cycling-dependent and-independent pathways
    • Kristal BS, Dubinsky JM. 1997. Mitochondrial permeability transition in the central nervous system: Induction by calcium cycling-dependent and -independent pathways. J Neurochem 69:524-538.
    • (1997) J Neurochem , vol.69 , pp. 524-538
    • Kristal, B.S.1    Dubinsky, J.M.2
  • 182
    • 3342967838 scopus 로고    scopus 로고
    • Metabolic stages, mitochondria, and calcium in hypoxic/ischemic brain damage
    • Kristian T. 2004. Metabolic stages, mitochondria, and calcium in hypoxic/ischemic brain damage. Cell Calcium 36:221-233.
    • (2004) Cell Calcium , vol.36 , pp. 221-233
    • Kristian, T.1
  • 183
    • 0034777484 scopus 로고    scopus 로고
    • Acidosis promotes the permeability transition in energized mitochondria: Implications for reperfusion injury
    • Kristian T, Bernardi P, Siesjo BK. 2001. Acidosis promotes the permeability transition in energized mitochondria: Implications for reperfusion injury. J Neurotrauma 18:1059-1074.
    • (2001) J Neurotrauma , vol.18 , pp. 1059-1074
    • Kristian, T.1    Bernardi, P.2    Siesjo, B.K.3
  • 184
    • 0034090710 scopus 로고    scopus 로고
    • Characteristics of the calcium-triggered mitochondrial permeability transition in nonsynaptic brain mitochondria: Effect of cyclosporin A and ubiquinone O
    • Kristian T, Gertsch J, Bates TE, Siesjo BK. 2000. Characteristics of the calcium-triggered mitochondrial permeability transition in nonsynaptic brain mitochondria: Effect of cyclosporin A and ubiquinone O. J Neurochem 74:1999-2009.
    • (2000) J Neurochem , vol.74 , pp. 1999-2009
    • Kristian, T.1    Gertsch, J.2    Bates, T.E.3    Siesjo, B.K.4
  • 185
    • 0242684750 scopus 로고    scopus 로고
    • Heterogeneity of the calcium-induced permeability transition in isolated nonsynaptic brain mitochondria
    • Kristian T, Weatherby TM, Bates TE, Fiskum G. 2002. Heterogeneity of the calcium-induced permeability transition in isolated nonsynaptic brain mitochondria. J Neurochem 83:1297-1308.
    • (2002) J Neurochem , vol.83 , pp. 1297-1308
    • Kristian, T.1    Weatherby, T.M.2    Bates, T.E.3    Fiskum, G.4
  • 186
    • 0031439426 scopus 로고    scopus 로고
    • The calmodulin antagonist trifluoperazine in transient focal brain ischemia in rats. Antiischemic effect and therapeutic window
    • Kuroda S, Nakai A, Kristian T, Siesjo BK. 1997. The calmodulin antagonist trifluoperazine in transient focal brain ischemia in rats. Antiischemic effect and therapeutic window. Stroke 28:2539-2544.
    • (1997) Stroke , vol.28 , pp. 2539-2544
    • Kuroda, S.1    Nakai, A.2    Kristian, T.3    Siesjo, B.K.4
  • 187
    • 0034655601 scopus 로고    scopus 로고
    • Prooxidants open both the mitochondrial permeability transition pore and a lowconductance channel in the inner mitochondrial membrane
    • Kushnareva YE, Sokolove PM. 2000. Prooxidants open both the mitochondrial permeability transition pore and a lowconductance channel in the inner mitochondrial membrane. Arch Biochem Biophys 376:377-388.
    • (2000) Arch Biochem Biophys , vol.376 , pp. 377-388
    • Kushnareva, Y.E.1    Sokolove, P.M.2
  • 189
    • 0028225879 scopus 로고
    • The mitochondrial permeability transition. Interactions of spermine, ADP, and inorganic phosphate
    • Lapidus RG, Sokolove PM. 1994. The mitochondrial permeability transition. Interactions of spermine, ADP, and inorganic phosphate. J Biol Chem 269:18931-18936.
    • (1994) J Biol Chem , vol.269 , pp. 18931-18936
    • Lapidus, R.G.1    Sokolove, P.M.2
  • 190
    • 0000848071 scopus 로고
    • Effect of surface active agents on the latent ATPase of mitochondria
    • Lardy HA, Pressman BC. 1956. Effect of surface active agents on the latent ATPase of mitochondria. Biochim Biophys Acta 21:458-466.
    • (1956) Biochim Biophys Acta , vol.21 , pp. 458-466
    • Lardy, H.A.1    Pressman, B.C.2
  • 191
    • 0021847071 scopus 로고
    • Crucial role of sulfhydryl groups in the mitochondrial inner membrane structure
    • Le-Quoc K, Le-Quoc D. 1985. Crucial role of sulfhydryl groups in the mitochondrial inner membrane structure. J Biol Chem 260:7422-7428.
    • (1985) J Biol Chem , vol.260 , pp. 7422-7428
    • Le-Quoc, K.1    Le-Quoc, D.2
  • 192
    • 18144447966 scopus 로고
    • Protective effect of organic Ca antagonists (iproveratril, D 600, prenylamine) against isoproterenol-induced myocardial necrosis
    • Leder O, Doring HJ, Reindell A, Fleckenstein A. 1969. Protective effect of organic Ca antagonists (iproveratril, D 600, prenylamine) against isoproterenol-induced myocardial necrosis. Pflugers Arch 312:R9-10.
    • (1969) Pflugers Arch , vol.312
    • Leder, O.1    Doring, H.J.2    Reindell, A.3    Fleckenstein, A.4
  • 193
    • 77957755462 scopus 로고
    • Esterification of inorganic phosphate coupled to electron transport between dihydrodiphosdphopyridine nucleotide and oxygen
    • Lehninger AL. 1949. Esterification of inorganic phosphate coupled to electron transport between dihydrodiphosdphopyridine nucleotide and oxygen. J Biol Chem 178:625-644.
    • (1949) J Biol Chem , vol.178 , pp. 625-644
    • Lehninger, A.L.1
  • 194
    • 0000955838 scopus 로고
    • Water uptake and extrusion by mitochondria in relation to oxidative phosphorylation
    • Lehninger AL. 1962. Water uptake and extrusion by mitochondria in relation to oxidative phosphorylation. Physiol Rev 42:467-517.
    • (1962) Physiol Rev , vol.42 , pp. 467-517
    • Lehninger, A.L.1
  • 195
    • 0004690804 scopus 로고
    • An endogenous uncoupling and swelling agent in liver mitochondria and its enzymic formation
    • Lehninger AL, Remmert LF. 1959. An endogenous uncoupling and swelling agent in liver mitochondria and its enzymic formation. J Biol Chem 234:2459-2464.
    • (1959) J Biol Chem , vol.234 , pp. 2459-2464
    • Lehninger, A.L.1    Remmert, L.F.2
  • 197
    • 0034597411 scopus 로고    scopus 로고
    • Cyclosporin A protects striatal neurons in vitro and in vivo from 3-nitropropionic acid toxicity
    • Leventhal L, Sortwell CE, Hanbury R, Collier TJ, Kordower JH, et al. 2000. Cyclosporin A protects striatal neurons in vitro and in vivo from 3-nitropropionic acid toxicity. J Comp Neurol 425:471-478.
    • (2000) J Comp Neurol , vol.425 , pp. 471-478
    • Leventhal, L.1    Sortwell, C.E.2    Hanbury, R.3    Collier, T.J.4    Kordower, J.H.5
  • 198
    • 0037163117 scopus 로고    scopus 로고
    • Mitochondrial targeted cyclophilin D protects cells from cell death by peptidyl prolyl isomerization
    • Lin DT, Lechleiter JD. 2002. Mitochondrial targeted cyclophilin D protects cells from cell death by peptidyl prolyl isomerization. J Biol Chem 277:31134-31141.
    • (2002) J Biol Chem , vol.277 , pp. 31134-31141
    • Lin, D.T.1    Lechleiter, J.D.2
  • 199
    • 0035667431 scopus 로고    scopus 로고
    • 2+-induced membrane permeability transition in brain mitochondria
    • 2+-induced membrane permeability transition in brain mitochondria. J Neurochem 79:1237-1245.
    • (2001) J Neurochem , vol.79 , pp. 1237-1245
    • Maciel, E.N.1    Vercesi, A.E.2    Castilho, R.F.3
  • 201
    • 9744221185 scopus 로고    scopus 로고
    • Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak
    • Majewski N, Nogueira V, Bhaskar P, Coy PE, Skeen JE, et al. 2004a. Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak. Mol Cell 16:819-830.
    • (2004) Mol Cell , vol.16 , pp. 819-830
    • Majewski, N.1    Nogueira, V.2    Bhaskar, P.3    Coy, P.E.4    Skeen, J.E.5
  • 202
    • 0347986675 scopus 로고    scopus 로고
    • Akt inhibits apoptosis downstream of BID cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases
    • Majewski N, Nogueira V, Robey RB, Hay N. 2004b. Akt inhibits apoptosis downstream of BID cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases. Mol Cell Biol 24:730-740.
    • (2004) Mol Cell Biol , vol.24 , pp. 730-740
    • Majewski, N.1    Nogueira, V.2    Robey, R.B.3    Hay, N.4
  • 203
    • 0031857554 scopus 로고    scopus 로고
    • Conformational changes in the mitochondrial channel protein, VDAC, and their functional implications
    • Mannella CA. 1998. Conformational changes in the mitochondrial channel protein, VDAC, and their functional implications. J Struct Biol 121:207-218.
    • (1998) J Struct Biol , vol.121 , pp. 207-218
    • Mannella, C.A.1
  • 204
    • 0032125488 scopus 로고    scopus 로고
    • Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis
    • Martin LJ, Al-Abdulla NA, Brambrink AM, Kirsch JR, Sieber FE, et al. 1998. Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis. Brain Res Bull 46:281-309.
    • (1998) Brain Res Bull , vol.46 , pp. 281-309
    • Martin, L.J.1    Al-Abdulla, N.A.2    Brambrink, A.M.3    Kirsch, J.R.4    Sieber, F.E.5
  • 205
    • 0032566649 scopus 로고    scopus 로고
    • Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis
    • Marzo I, Brenner C, Zamzami N, Jurgensmeier JM, Susin SA, et al. 1998a. Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science 281:2027-2031.
    • (1998) Science , vol.281 , pp. 2027-2031
    • Marzo, I.1    Brenner, C.2    Zamzami, N.3    Jurgensmeier, J.M.4    Susin, S.A.5
  • 206
    • 0032550363 scopus 로고    scopus 로고
    • The permeability transition pore complex: A target for apoptosis regulation by caspases and bcl-2-related proteins
    • Marzo I, Brenner C, Zamzami N, Susin SA, Beutner G, et al. 1998b. The permeability transition pore complex: A target for apoptosis regulation by caspases and bcl-2-related proteins. J Exp Med 187:1261-1271.
    • (1998) J Exp Med , vol.187 , pp. 1261-1271
    • Marzo, I.1    Brenner, C.2    Zamzami, N.3    Susin, S.A.4    Beutner, G.5
  • 207
    • 0033495895 scopus 로고    scopus 로고
    • Blockade of the mitochondrial permeability transition pore diminishes infarct size in the rat after transient middle cerebral artery occlusion
    • Matsumoto S, Friberg H, Ferrand-Drake M, Wieloch T. 1999. Blockade of the mitochondrial permeability transition pore diminishes infarct size in the rat after transient middle cerebral artery occlusion. J Cereb Blood Flow Metab 19:736-741.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 736-741
    • Matsumoto, S.1    Friberg, H.2    Ferrand-Drake, M.3    Wieloch, T.4
  • 208
    • 0031964359 scopus 로고    scopus 로고
    • Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease
    • Matthews RT, Yang L, Jenkins BG, Ferrante RJ, Rosen BR, et al. 1998. Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease. J Neurosci 18:156-163.
    • (1998) J Neurosci , vol.18 , pp. 156-163
    • Matthews, R.T.1    Yang, L.2    Jenkins, B.G.3    Ferrante, R.J.4    Rosen, B.R.5
  • 209
    • 0141987911 scopus 로고    scopus 로고
    • Flow cytometric analysis of mitochondria from CA1 and CA3 regions of rat hippocampus reveals differences in permeability transition pore activation
    • Mattiasson G, Friberg H, Hansson M, Elmer E, Wieloch T. 2003. Flow cytometric analysis of mitochondria from CA1 and CA3 regions of rat hippocampus reveals differences in permeability transition pore activation. J Neurochem 87:532-544.
    • (2003) J Neurochem , vol.87 , pp. 532-544
    • Mattiasson, G.1    Friberg, H.2    Hansson, M.3    Elmer, E.4    Wieloch, T.5
  • 210
    • 0026538576 scopus 로고
    • The mitochondrial benzodiazepine receptor: Evidence for association with the voltage-dependent anion channel (VDAC)
    • McEnery MW. 1992. The mitochondrial benzodiazepine receptor: Evidence for association with the voltage-dependent anion channel (VDAC). J Bioenerg Biomembr 24:63-69.
    • (1992) J Bioenerg Biomembr , vol.24 , pp. 63-69
    • McEnery, M.W.1
  • 211
    • 0026591024 scopus 로고
    • Isolation of the mitochondrial benzodiazepine receptor: Association with the voltage-dependent anion channel and the adenine nucleotide carrier
    • McEnery MW, Snowman AM, Trifiletti RR, Snyder SH. 1992. Isolation of the mitochondrial benzodiazepine receptor: Association with the voltage-dependent anion channel and the adenine nucleotide carrier. Proc Natl Acad Sci USA 89:3170-3174.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 3170-3174
    • McEnery, M.W.1    Snowman, A.M.2    Trifiletti, R.R.3    Snyder, S.H.4
  • 213
    • 0037109064 scopus 로고    scopus 로고
    • Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore
    • McStay GP, Clarke SJ, Halestrap AP. 2002. Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore. Biochem J 367:541-548.
    • (2002) Biochem J , vol.367 , pp. 541-548
    • McStay, G.P.1    Clarke, S.J.2    Halestrap, A.P.3
  • 214
    • 33645319458 scopus 로고    scopus 로고
    • Clinical treatments for mitochondrial dysfunctions after brain injury
    • Merenda A, Bullock R. 2006. Clinical treatments for mitochondrial dysfunctions after brain injury. Curr Opin Crit Care 12:90-96.
    • (2006) Curr Opin Crit Care , vol.12 , pp. 90-96
    • Merenda, A.1    Bullock, R.2
  • 215
    • 0030993026 scopus 로고    scopus 로고
    • Expression of functional mitochondrial creatine kinase in liver of transgenic mice
    • Miller K, Sharer K, Suhan J, Koretsky AP. 1997. Expression of functional mitochondrial creatine kinase in liver of transgenic mice. Am J Physiol 272:C1193-C1202.
    • (1997) Am J Physiol , vol.272
    • Miller, K.1    Sharer, K.2    Suhan, J.3    Koretsky, A.P.4
  • 216
    • 0034640519 scopus 로고    scopus 로고
    • The human nm23-H4 gene product is a mitochondrial nucleoside diphosphate kinase
    • Milon L, Meyer P, Chiadmi M, Munier A, Johansson M, et al. 2000. The human nm23-H4 gene product is a mitochondrial nucleoside diphosphate kinase. J Biol Chem 275:14264-14272.
    • (2000) J Biol Chem , vol.275 , pp. 14264-14272
    • Milon, L.1    Meyer, P.2    Chiadmi, M.3    Munier, A.4    Johansson, M.5
  • 217
    • 0033540289 scopus 로고    scopus 로고
    • Mitochondrial permeability transition and swelling can occur reversibly without inducing cell death in intact human cells
    • Minamikawa T, Williams DA, Bowser DN, Nagley P. 1999. Mitochondrial permeability transition and swelling can occur reversibly without inducing cell death in intact human cells. Exp Cell Res 246:26-37.
    • (1999) Exp Cell Res , vol.246 , pp. 26-37
    • Minamikawa, T.1    Williams, D.A.2    Bowser, D.N.3    Nagley, P.4
  • 219
    • 13844275276 scopus 로고    scopus 로고
    • Brain mitochondrial injury induced by oxidative stress-related events is prevented by tamoxifen
    • Moreira PI, Custodio JB, Oliveira CR, Santos MS. 2005. Brain mitochondrial injury induced by oxidative stress-related events is prevented by tamoxifen. Neuropharmacology 48:435-447.
    • (2005) Neuropharmacology , vol.48 , pp. 435-447
    • Moreira, P.I.1    Custodio, J.B.2    Oliveira, C.R.3    Santos, M.S.4
  • 220
    • 15844407874 scopus 로고    scopus 로고
    • Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
    • Nakagawa T, Shimizu S, Watanabe T, Yamaguchi O, Otsu K, et al. 2005. Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 434:652-658.
    • (2005) Nature , vol.434 , pp. 652-658
    • Nakagawa, T.1    Shimizu, S.2    Watanabe, T.3    Yamaguchi, O.4    Otsu, K.5
  • 221
    • 0026728095 scopus 로고
    • Protective effects of serotonin reuptake inhibitors, citalopram and clomipramine, against hippocampal CA1 neuronal damage following transient ischemia in the gerbil
    • Nakata N, Kato H, Kogure K. 1992. Protective effects of serotonin reuptake inhibitors, citalopram and clomipramine, against hippocampal CA1 neuronal damage following transient ischemia in the gerbil. Brain Res 590:48-52.
    • (1992) Brain Res , vol.590 , pp. 48-52
    • Nakata, N.1    Kato, H.2    Kogure, K.3
  • 222
    • 0032422488 scopus 로고    scopus 로고
    • Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria
    • Narita M, Shimizu S, Ito T, Chittenden T, Lutz RJ, et al. 1998. Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria. Proc Natl Acad Sci USA 95:14681-14686.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 14681-14686
    • Narita, M.1    Shimizu, S.2    Ito, T.3    Chittenden, T.4    Lutz, R.J.5
  • 223
    • 0141533205 scopus 로고    scopus 로고
    • New roles for astrocytes: Redefining the functional architecture of the brain
    • Nedergaard M, Ransom B, Goldman SA. 2003. New roles for astrocytes: Redefining the functional architecture of the brain. Trends Neurosci 26:523-530.
    • (2003) Trends Neurosci , vol.26 , pp. 523-530
    • Nedergaard, M.1    Ransom, B.2    Goldman, S.A.3
  • 224
    • 0037459081 scopus 로고    scopus 로고
    • Mitochondria: Releasing power for life and unleashing the machineries of death
    • Newmeyer DD, Ferguson-Miller S. 2003. Mitochondria: Releasing power for life and unleashing the machineries of death. Cell 112:481-490.
    • (2003) Cell , vol.112 , pp. 481-490
    • Newmeyer, D.D.1    Ferguson-Miller, S.2
  • 225
    • 0032504708 scopus 로고    scopus 로고
    • Mitochondria and neuronal glutamate excitotoxicity
    • Nicholls DG, Budd SL. 1998. Mitochondria and neuronal glutamate excitotoxicity. Biochim Biophys Acta 1366:97-112.
    • (1998) Biochim Biophys Acta , vol.1366 , pp. 97-112
    • Nicholls, D.G.1    Budd, S.L.2
  • 226
    • 10244257617 scopus 로고    scopus 로고
    • The integration of mitochondrial calcium transport and storage
    • Nicholls DG, Chalmers S. 2004. The integration of mitochondrial calcium transport and storage. J Bioenerg Biomembr 36:277-281.
    • (2004) J Bioenerg Biomembr , vol.36 , pp. 277-281
    • Nicholls, D.G.1    Chalmers, S.2
  • 227
    • 0019324973 scopus 로고
    • The regulation of brain mitochondrial calcium ion transport. The role of ATP in the discrimination between kinetic and membrane potentialdependent calcium ion efflux mechanisms
    • Nicholls DG, Scott ID. 1980. The regulation of brain mitochondrial calcium ion transport. The role of ATP in the discrimination between kinetic and membrane potentialdependent calcium ion efflux mechanisms. Biochem J 186:833-839.
    • (1980) Biochem J , vol.186 , pp. 833-839
    • Nicholls, D.G.1    Scott, I.D.2
  • 228
    • 0034176843 scopus 로고    scopus 로고
    • Mitochondrial membrane potential and neuronal glutamate excitotoxicity: Mortality and millivolts
    • Nicholls DG, Ward MW. 2000. Mitochondrial membrane potential and neuronal glutamate excitotoxicity: Mortality and millivolts. Trends Neurosci 23:166-174.
    • (2000) Trends Neurosci , vol.23 , pp. 166-174
    • Nicholls, D.G.1    Ward, M.W.2
  • 229
    • 0027207302 scopus 로고
    • Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by matrix pH. Evidence that the pore open-closed probability is regulated by reversible histidine protonation
    • Nicolli A, Petronilli V, Bernardi P. 1993. Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by matrix pH. Evidence that the pore open-closed probability is regulated by reversible histidine protonation. Biochemistry 32:4461-4465.
    • (1993) Biochemistry , vol.32 , pp. 4461-4465
    • Nicolli, A.1    Petronilli, V.2    Bernardi, P.3
  • 230
    • 0030298459 scopus 로고    scopus 로고
    • Cyclosporin A delays mitochondrial depolarization induced by N-methyl-D-aspartate in cortical neurons: Evidence of the mitochondrial permeability transition
    • Nieminen AL, Petrie TG, Lemasters JJ, Selman WR. 1996. Cyclosporin A delays mitochondrial depolarization induced by N-methyl-D-aspartate in cortical neurons: Evidence of the mitochondrial permeability transition. Neuroscience 75:993-997.
    • (1996) Neuroscience , vol.75 , pp. 993-997
    • Nieminen, A.L.1    Petrie, T.G.2    Lemasters, J.J.3    Selman, W.R.4
  • 231
    • 0028923778 scopus 로고
    • Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide
    • Nieminen AL, Saylor AK, Tesfai SA, Herman B, Lemasters JJ. 1995. Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide. Biochem J 307(Pt 1):99-106.
    • (1995) Biochem J , vol.307 , Issue.PART 1 , pp. 99-106
    • Nieminen, A.L.1    Saylor, A.K.2    Tesfai, S.A.3    Herman, B.4    Lemasters, J.J.5
  • 233
    • 0028340683 scopus 로고
    • Magnesium ion modulates the sensitivity of the mitochondrial permeability transition pore to cyclosporin A and ADP
    • Novgorodov SA, Gudz TI, Brierley GP, Pfeiffer DR. 1994. Magnesium ion modulates the sensitivity of the mitochondrial permeability transition pore to cyclosporin A and ADP. Arch Biochem Biophys 311:219-228.
    • (1994) Arch Biochem Biophys , vol.311 , pp. 219-228
    • Novgorodov, S.A.1    Gudz, T.I.2    Brierley, G.P.3    Pfeiffer, D.R.4
  • 234
    • 0025679160 scopus 로고
    • Effect of ADP/ATP antiporter conformational state on the suppression of the nonspecific permeability of the inner mitochondrial membrane by cyclosporin A
    • Novgorodov SA, Gudz TI, Kushnareva YE, Zorov DB, Kudrjashov YB. 1990. Effect of ADP/ATP antiporter conformational state on the suppression of the nonspecific permeability of the inner mitochondrial membrane by cyclosporin A. FEBS Lett 277:123-126.
    • (1990) FEBS Lett , vol.277 , pp. 123-126
    • Novgorodov, S.A.1    Gudz, T.I.2    Kushnareva, Y.E.3    Zorov, D.B.4    Kudrjashov, Y.B.5
  • 235
    • 0026742968 scopus 로고
    • The permeability transition in heart mitochondria is regulated synergistically by ADP and cyclosporin A
    • Novgorodov SA, Gudz TI, Milgrom YM, Brierley GP. 1992. The permeability transition in heart mitochondria is regulated synergistically by ADP and cyclosporin A. J Biol Chem 267:16274-16282.
    • (1992) J Biol Chem , vol.267 , pp. 16274-16282
    • Novgorodov, S.A.1    Gudz, T.I.2    Milgrom, Y.M.3    Brierley, G.P.4
  • 236
    • 0031559949 scopus 로고    scopus 로고
    • The role of creatine kinase in inhibition of mitochondrial permeability transition
    • O'Gorman E, Beutner G, Dolder M, Koretsky AP, Brdiczka D, et al. 1997. The role of creatine kinase in inhibition of mitochondrial permeability transition. FEBS Lett 414:253-257.
    • (1997) FEBS Lett , vol.414 , pp. 253-257
    • O'Gorman, E.1    Beutner, G.2    Dolder, M.3    Koretsky, A.P.4    Brdiczka, D.5
  • 237
    • 0033509493 scopus 로고    scopus 로고
    • An intrathecal bolus of cyclosporin A before injury preserves mitochondrial integrity and attenuates axonal disruption in traumatic brain injury
    • Okonkwo DO, Povlishock JT. 1999. An intrathecal bolus of cyclosporin A before injury preserves mitochondrial integrity and attenuates axonal disruption in traumatic brain injury. J Cereb Blood Flow Metab 19:443-451.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 443-451
    • Okonkwo, D.O.1    Povlishock, J.T.2
  • 238
    • 0037416358 scopus 로고    scopus 로고
    • Dose-response of cyclosporin A in attenuating traumatic axonal injury in rat
    • Okonkwo DO, Melon DE, Pellicane AJ, Mutlu LK, Rubin DG, et al. 2003. Dose-response of cyclosporin A in attenuating traumatic axonal injury in rat. Neuroreport 14:463-466.
    • (2003) Neuroreport , vol.14 , pp. 463-466
    • Okonkwo, D.O.1    Melon, D.E.2    Pellicane, A.J.3    Mutlu, L.K.4    Rubin, D.G.5
  • 239
    • 0033503975 scopus 로고    scopus 로고
    • Survival- and death-promoting events after transient cerebral ischemia: Phosphorylation of Akt, release of cytochrome c, and activation of caspase-like proteases
    • Ouyang YB, Tan Y, Comb M, Liu CL, Martone ME, et al. 1999. Survival- and death-promoting events after transient cerebral ischemia: Phosphorylation of Akt, release of cytochrome c, and activation of caspase-like proteases. J Cereb Blood Flow Metab 19:1126-1135.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 1126-1135
    • Ouyang, Y.B.1    Tan, Y.2    Comb, M.3    Liu, C.L.4    Martone, M.E.5
  • 240
    • 0026732816 scopus 로고
    • Classification of compounds for prevention of NMDLA-induced seizures/mortality, or maximal electroshock and pentylenetetrazol seizures in mice and antagonism of MK801 binding in vitro
    • Palmer GC, Harris EW, Ray R, Stagnitto ML, Schmiesing RJ. 1992. Classification of compounds for prevention of NMDLA-induced seizures/mortality, or maximal electroshock and pentylenetetrazol seizures in mice and antagonism of MK801 binding in vitro. Arch Int Pharmacodyn Ther 317:16-34.
    • (1992) Arch Int Pharmacodyn Ther , vol.317 , pp. 16-34
    • Palmer, G.C.1    Harris, E.W.2    Ray, R.3    Stagnitto, M.L.4    Schmiesing, R.J.5
  • 241
    • 1242317666 scopus 로고    scopus 로고
    • The mitochondrial transporter family (SLC25): Physiological and pathological implications
    • Palmieri F. 2004. The mitochondrial transporter family (SLC25): Physiological and pathological implications. Pflugers Arch 447:689-709.
    • (2004) Pflugers Arch , vol.447 , pp. 689-709
    • Palmieri, F.1
  • 242
    • 29644447278 scopus 로고    scopus 로고
    • Rotenone model of Parkinson disease: Multiple brain mitochondria dysfunctions after short-term systemic rotenone intoxication
    • Panov A, Dikalov S, Shalbuyeva N, Taylor G, Sherer T, et al. 2005. Rotenone model of Parkinson disease: Multiple brain mitochondria dysfunctions after short-term systemic rotenone intoxication. J Biol Chem 280:42026-42035.
    • (2005) J Biol Chem , vol.280 , pp. 42026-42035
    • Panov, A.1    Dikalov, S.2    Shalbuyeva, N.3    Taylor, G.4    Sherer, T.5
  • 243
    • 1542268971 scopus 로고    scopus 로고
    • Quantitative evaluation of the effects of mitochondrial permeability transition pore modifiers on accumulation of calcium phosphate: Comparison of rat liver and brain mitochondria
    • Panov AV, Andreeva L, Greenamyre JT. 2004. Quantitative evaluation of the effects of mitochondrial permeability transition pore modifiers on accumulation of calcium phosphate: Comparison of rat liver and brain mitochondria. Arch Biochem Biophys 424:44-52.
    • (2004) Arch Biochem Biophys , vol.424 , pp. 44-52
    • Panov, A.V.1    Andreeva, L.2    Greenamyre, J.T.3
  • 244
    • 0031031675 scopus 로고    scopus 로고
    • Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis
    • Papadopoulos V, Amri H, Boujrad N, Cascio C, Culty M, et al. 1997. Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis. Steroids 62:21-28.
    • (1997) Steroids , vol.62 , pp. 21-28
    • Papadopoulos, V.1    Amri, H.2    Boujrad, N.3    Cascio, C.4    Culty, M.5
  • 245
    • 0036645380 scopus 로고    scopus 로고
    • Platelet-activating factor induces permeability transition and cytochrome c release in isolated brain mitochondria
    • Parker MA, Bazan HE, Marcheselli V, Rodriguez de Turco EB, Bazan NG. 2002. Platelet-activating factor induces permeability transition and cytochrome c release in isolated brain mitochondria. J Neurosci Res 69:39-50.
    • (2002) J Neurosci Res , vol.69 , pp. 39-50
    • Parker, M.A.1    Bazan, H.E.2    Marcheselli, V.3    Rodriguez De Turco, E.B.4    Bazan, N.G.5
  • 246
    • 0346727130 scopus 로고    scopus 로고
    • Evolutionary conservation of biogenesis of β-barrel membrane proteins
    • Paschen SA, Waizenegger T, Stan T, Preuss M, Cyrklaff M, et al. 2003. Evolutionary conservation of biogenesis of β-barrel membrane proteins. Nature 426:862-866.
    • (2003) Nature , vol.426 , pp. 862-866
    • Paschen, S.A.1    Waizenegger, T.2    Stan, T.3    Preuss, M.4    Cyrklaff, M.5
  • 247
    • 0041309460 scopus 로고    scopus 로고
    • Hexokinase II: The integration of energy metabolism and control of apoptosis
    • Pastorino JG, Hoek JB. 2003. Hexokinase II: The integration of energy metabolism and control of apoptosis. Curr Med Chem 10:1535-1551.
    • (2003) Curr Med Chem , vol.10 , pp. 1535-1551
    • Pastorino, J.G.1    Hoek, J.B.2
  • 248
    • 0032571294 scopus 로고    scopus 로고
    • The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition
    • Pastorino JG, Chen ST, Tafani M, Snyder JW, Farber JL. 1998. The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition. J Biol Chem 273:7770-7775.
    • (1998) J Biol Chem , vol.273 , pp. 7770-7775
    • Pastorino, J.G.1    Chen, S.T.2    Tafani, M.3    Snyder, J.W.4    Farber, J.L.5
  • 249
    • 28544436922 scopus 로고    scopus 로고
    • Activation of glycogen synthase kinase 3β disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity
    • Pastorino JG, Hoek JB, Shulga N. 2005. Activation of glycogen synthase kinase 3β disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity. Cancer Res 65:10545-10554.
    • (2005) Cancer Res , vol.65 , pp. 10545-10554
    • Pastorino, J.G.1    Hoek, J.B.2    Shulga, N.3
  • 250
    • 0036510541 scopus 로고    scopus 로고
    • Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis
    • Pastorino JG, Shulga N, Hoek JB. 2002. Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis. J Biol Chem 277:7610-7618.
    • (2002) J Biol Chem , vol.277 , pp. 7610-7618
    • Pastorino, J.G.1    Shulga, N.2    Hoek, J.B.3
  • 251
    • 0033615649 scopus 로고    scopus 로고
    • Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore
    • Pastorino JG, Tafani M, Rothman RJ, Marcineviciute A, Hoek JB, et al. 1999. Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore. J Biol Chem 274:31734-31739.
    • (1999) J Biol Chem , vol.274 , pp. 31734-31739
    • Pastorino, J.G.1    Tafani, M.2    Rothman, R.J.3    Marcineviciute, A.4    Hoek, J.B.5
  • 254
    • 0027433653 scopus 로고
    • Physiological effectors modify voltage sensing by the cyclosporin A-sensitive permeability transition pore of mitochondria
    • Petronilli V, Cola C, Massari S, Colonna R, Bernardi P. 1993b. Physiological effectors modify voltage sensing by the cyclosporin A-sensitive permeability transition pore of mitochondria. J Biol Chem 268:21939-21945.
    • (1993) J Biol Chem , vol.268 , pp. 21939-21945
    • Petronilli, V.1    Cola, C.2    Massari, S.3    Colonna, R.4    Bernardi, P.5
  • 255
    • 0028239794 scopus 로고
    • The voltage sensor of the mitochondrial permeability transition pore is tuned by the oxidation-reduction state of vicinal thiols. Increase of the gating potential by oxidants and its reversal by reducing agents
    • Petronilli V, Costantini P, Scorrano L, Colonna R, Passamonti S, et al. 1994a. The voltage sensor of the mitochondrial permeability transition pore is tuned by the oxidation-reduction state of vicinal thiols. Increase of the gating potential by oxidants and its reversal by reducing agents. J Biol Chem 269:16638-16642.
    • (1994) J Biol Chem , vol.269 , pp. 16638-16642
    • Petronilli, V.1    Costantini, P.2    Scorrano, L.3    Colonna, R.4    Passamonti, S.5
  • 256
    • 0028074839 scopus 로고
    • Regulation of the permeability transition pore, a voltage-dependent mitochondrial channel inhibited by cyclosporin A
    • Petronilli V, Nicolli A, Costantini P, Colonna R, Bernardi P. 1994b. Regulation of the permeability transition pore, a voltage-dependent mitochondrial channel inhibited by cyclosporin A. Biochim Biophys Acta 1187:255-259.
    • (1994) Biochim Biophys Acta , vol.1187 , pp. 255-259
    • Petronilli, V.1    Nicolli, A.2    Costantini, P.3    Colonna, R.4    Bernardi, P.5
  • 257
    • 0033021780 scopus 로고    scopus 로고
    • Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence
    • Petronilli V, Miotto G, Canton M, Brini M, Colonna R, et al. 1999. Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence. Biophys J 76:725-734.
    • (1999) Biophys J , vol.76 , pp. 725-734
    • Petronilli, V.1    Miotto, G.2    Canton, M.3    Brini, M.4    Colonna, R.5
  • 258
    • 0024787657 scopus 로고
    • The inner mitochondrial membrane contains ion-conducting channels similar to those found in bacteria
    • Petronilli V, Szabo I, Zoratti M. 1989. The inner mitochondrial membrane contains ion-conducting channels similar to those found in bacteria. FEBS Lett 259:137-143.
    • (1989) FEBS Lett , vol.259 , pp. 137-143
    • Petronilli, V.1    Szabo, I.2    Zoratti, M.3
  • 261
    • 4544298249 scopus 로고    scopus 로고
    • Mitochondrial mechanisms of neural cell apoptosis
    • Polster BM, Fiskum G. 2004. Mitochondrial mechanisms of neural cell apoptosis. J Neurochem 90:1281-1289.
    • (2004) J Neurochem , vol.90 , pp. 1281-1289
    • Polster, B.M.1    Fiskum, G.2
  • 262
    • 84900907271 scopus 로고
    • The assay of animal tissues for respiratory enzymes. VI. Further studies on oxidative phosphorylation
    • Potter VR. 1947. The assay of animal tissues for respiratory enzymes. VI. Further studies on oxidative phosphorylation. J Biol Chem 169:17-37.
    • (1947) J Biol Chem , vol.169 , pp. 17-37
    • Potter, V.R.1
  • 263
    • 0035742481 scopus 로고    scopus 로고
    • Cerebral hypoxia-ischemia in immature rats: Involvement of mitochondrial permeability transition?
    • Puka-Sundvall M, Gilland E, Hagberg H. 2001. Cerebral hypoxia-ischemia in immature rats: Involvement of mitochondrial permeability transition? Dev Neurosci 23:192-197.
    • (2001) Dev Neurosci , vol.23 , pp. 192-197
    • Puka-Sundvall, M.1    Gilland, E.2    Hagberg, H.3
  • 264
    • 84960993949 scopus 로고
    • Swelling of isolated mitochondria of the liver and their susceptibility to physicochemical influences
    • Raaflaub J. 1953. Swelling of isolated mitochondria of the liver and their susceptibility to physicochemical influences. Helv Physiol Pharmacol Acta 11:142-156.
    • (1953) Helv Physiol Pharmacol Acta , vol.11 , pp. 142-156
    • Raaflaub, J.1
  • 265
    • 0038509984 scopus 로고    scopus 로고
    • Ammonia neurotoxicity: Role of the mitochondrial permeability transition
    • Rama Rao KV, Jayakumar AR, Norenberg DM. 2003. Ammonia neurotoxicity: Role of the mitochondrial permeability transition. Metab Brain Dis 18:113-127.
    • (2003) Metab Brain Dis , vol.18 , pp. 113-127
    • Rama Rao, K.V.1    Jayakumar, A.R.2    Norenberg, D.M.3
  • 266
    • 20544437331 scopus 로고    scopus 로고
    • Role of oxidative stress in the ammonia-induced mitochondrial permeability transition in cultured astrocytes
    • Rama Rao KV, Jayakumar AR, Norenberg MD. 2005. Role of oxidative stress in the ammonia-induced mitochondrial permeability transition in cultured astrocytes. Neurochem Int 47:31-38.
    • (2005) Neurochem Int , vol.47 , pp. 31-38
    • Rama Rao, K.V.1    Jayakumar, A.R.2    Norenberg, M.D.3
  • 267
    • 0035449974 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore and nitric oxide synthase mediate early mitochondrial depolarization in astrocytes during oxygen-glucose deprivation
    • Reichert SA, Kim-Han JS, Dugan LL. 2001. The mitochondrial permeability transition pore and nitric oxide synthase mediate early mitochondrial depolarization in astrocytes during oxygen-glucose deprivation. J Neurosci 21:6608-6616.
    • (2001) J Neurosci , vol.21 , pp. 6608-6616
    • Reichert, S.A.1    Kim-Han, J.S.2    Dugan, L.L.3
  • 268
    • 0033559011 scopus 로고    scopus 로고
    • Influence of calcium and iron on cell death and mitochondrial function in oxidatively stressed astrocytes
    • Robb SJ, Robb-Gaspers LD, Scaduto RC, Jr., Thomas AP, Connor JR. 1999. Influence of calcium and iron on cell death and mitochondrial function in oxidatively stressed astrocytes. J Neurosci Res 55:674-686.
    • (1999) J Neurosci Res , vol.55 , pp. 674-686
    • Robb, S.J.1    Robb-Gaspers, L.D.2    Scaduto Jr., R.C.3    Thomas, A.P.4    Connor, J.R.5
  • 269
  • 272
    • 28244437805 scopus 로고    scopus 로고
    • The temperature dependence and involvement of mitochondria permeability transition and caspase activation in damage to organotypic hippocampal slices following in vitro ischemia
    • Rytter A, Cardoso CM, Johansson P, Cronberg T, Hansson MJ, et al. 2005. The temperature dependence and involvement of mitochondria permeability transition and caspase activation in damage to organotypic hippocampal slices following in vitro ischemia. J Neurochem 95:1108-1117.
    • (2005) J Neurochem , vol.95 , pp. 1108-1117
    • Rytter, A.1    Cardoso, C.M.2    Johansson, P.3    Cronberg, T.4    Hansson, M.J.5
  • 274
    • 0035914399 scopus 로고    scopus 로고
    • Immotile sperm and infertility in mice lacking mitochondrial voltage-dependent anion channel type 3
    • Sampson MJ, Decker WK, Beaudet AL, Ruitenbeek W, Armstrong D, et al. 2001. Immotile sperm and infertility in mice lacking mitochondrial voltage-dependent anion channel type 3. J Biol Chem 276:39206-39212.
    • (2001) J Biol Chem , vol.276 , pp. 39206-39212
    • Sampson, M.J.1    Decker, W.K.2    Beaudet, A.L.3    Ruitenbeek, W.4    Armstrong, D.5
  • 275
    • 0034998271 scopus 로고    scopus 로고
    • Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction
    • discussion 1399-1401
    • Sanchez Mejia RO, Ona VO, Li M, Friedlander RM. 2001. Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction. Neurosurgery 48:1393-1399; discussion 1399-1401.
    • (2001) Neurosurgery , vol.48 , pp. 1393-1399
    • Sanchez Mejia, R.O.1    Ona, V.O.2    Li, M.3    Friedlander, R.M.4
  • 276
    • 0043073123 scopus 로고    scopus 로고
    • Protection provided by cyclosporin A against excitotoxic neuronal death is genotype dependent
    • Santos JB, Schauwecker PE. 2003. Protection provided by cyclosporin A against excitotoxic neuronal death is genotype dependent. Epilepsia 44:995-1002.
    • (2003) Epilepsia , vol.44 , pp. 995-1002
    • Santos, J.B.1    Schauwecker, P.E.2
  • 277
    • 0018636340 scopus 로고
    • Calcium dependence of toxic cell death: A final common pathway
    • Schanne FA, Kane AB, Young EE, Farber JL. 1979. Calcium dependence of toxic cell death: A final common pathway. Science 206:700-702.
    • (1979) Science , vol.206 , pp. 700-702
    • Schanne, F.A.1    Kane, A.B.2    Young, E.E.3    Farber, J.L.4
  • 278
    • 0029810095 scopus 로고    scopus 로고
    • Mitochondrial dysfunction is a primary event in glutamate neurotoxicity
    • Schinder AF, Olson EC, Spitzer NC, Montal M. 1996. Mitochondrial dysfunction is a primary event in glutamate neurotoxicity. J Neurosci 16:6125-6133.
    • (1996) J Neurosci , vol.16 , pp. 6125-6133
    • Schinder, A.F.1    Olson, E.C.2    Spitzer, N.C.3    Montal, M.4
  • 279
    • 24744460273 scopus 로고    scopus 로고
    • Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia
    • Schinzel AC, Takeuchi O, Huang Z, Fisher JK, Zhou Z, et al. 2005. Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia. Proc Natl Acad Sci USA 102:12005-12010.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 12005-12010
    • Schinzel, A.C.1    Takeuchi, O.2    Huang, Z.3    Fisher, J.K.4    Zhou, Z.5
  • 280
    • 0034705558 scopus 로고    scopus 로고
    • Differential changes of bax, caspase-3, and p21 mRNA expression after transient focal brain ischemia in the rat
    • Schmidt-Kastner R, Truettner J, Zhao W, Belayev L, Krieger C, et al. 2000. Differential changes of bax, caspase-3, and p21 mRNA expression after transient focal brain ischemia in the rat. Brain Res Mol Brain Res 79:88-101.
    • (2000) Brain Res Mol Brain Res , vol.79 , pp. 88-101
    • Schmidt-Kastner, R.1    Truettner, J.2    Zhao, W.3    Belayev, L.4    Krieger, C.5
  • 281
    • 0037314215 scopus 로고    scopus 로고
    • Neuronal degeneration and mitochondrial dysfunction
    • Schon EA, Manfredi G. 2003. Neuronal degeneration and mitochondrial dysfunction. J Clin Invest 111:303-312.
    • (2003) J Clin Invest , vol.111 , pp. 303-312
    • Schon, E.A.1    Manfredi, G.2
  • 282
    • 0031590634 scopus 로고    scopus 로고
    • Fatty acid-promoted mitochondrial permeability transition by membrane depolarization and binding to the ADP/ATP carrier
    • Schonfeld P, Bohnensack R. 1997. Fatty acid-promoted mitochondrial permeability transition by membrane depolarization and binding to the ADP/ATP carrier. FEBS Lett 420:167-170.
    • (1997) FEBS Lett , vol.420 , pp. 167-170
    • Schonfeld, P.1    Bohnensack, R.2
  • 283
    • 1542332908 scopus 로고    scopus 로고
    • Cyclophilin D, a component of the permeability transition-pore, is an apoptosis repressor
    • Schubert A, Grimm S. 2004. Cyclophilin D, a component of the permeability transition-pore, is an apoptosis repressor. Cancer Res 64:85-93.
    • (2004) Cancer Res , vol.64 , pp. 85-93
    • Schubert, A.1    Grimm, S.2
  • 284
    • 0021765973 scopus 로고
    • Immunochemical characterization of the adenine nucleotide translocator. Organ specificity and conformation specificity
    • Schultheiss HP, Klingenberg M. 1984. Immunochemical characterization of the adenine nucleotide translocator. Organ specificity and conformation specificity. Eur J Biochem 143:599-605.
    • (1984) Eur J Biochem , vol.143 , pp. 599-605
    • Schultheiss, H.P.1    Klingenberg, M.2
  • 285
    • 0036007116 scopus 로고    scopus 로고
    • A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis
    • Scorrano L, Ashiya M, Buttle K, Weiler S, Oakes SA, et al. 2002. A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis. Dev Cell 2:55-67.
    • (2002) Dev Cell , vol.2 , pp. 55-67
    • Scorrano, L.1    Ashiya, M.2    Buttle, K.3    Weiler, S.4    Oakes, S.A.5
  • 286
    • 0030766182 scopus 로고    scopus 로고
    • Two modes of activation of the permeability transition pore: The role of mitochondrial cyclophilin
    • Scorrano L, Nicolli A, Basso E, Petronilli V, Bernardi P. 1997. Two modes of activation of the permeability transition pore: The role of mitochondrial cyclophilin. Mol Cell Biochem 174:181-184.
    • (1997) Mol Cell Biochem , vol.174 , pp. 181-184
    • Scorrano, L.1    Nicolli, A.2    Basso, E.3    Petronilli, V.4    Bernardi, P.5
  • 287
    • 0035853767 scopus 로고    scopus 로고
    • Arachidonic acid causes cell death through the mitochondrial permeability transition. Implications for tumor necrosis factor-A aopototic signaling
    • Scorrano L, Penzo D, Petronilli V, Pagano F, Bernardi P. 2001. Arachidonic acid causes cell death through the mitochondrial permeability transition. Implications for tumor necrosis factor-A aopototic signaling. J Biol Chem 276:12035-12040.
    • (2001) J Biol Chem , vol.276 , pp. 12035-12040
    • Scorrano, L.1    Penzo, D.2    Petronilli, V.3    Pagano, F.4    Bernardi, P.5
  • 288
    • 0026446691 scopus 로고
    • Cyclosporin A protects against ischemia-reperfusion injury in the brain
    • Shiga Y, Onodera H, Matsuo Y, Kogure K. 1992. Cyclosporin A protects against ischemia-reperfusion injury in the brain. Brain Res 595:145-148.
    • (1992) Brain Res , vol.595 , pp. 145-148
    • Shiga, Y.1    Onodera, H.2    Matsuo, Y.3    Kogure, K.4
  • 289
    • 0019842691 scopus 로고
    • Cell damage in the brain: A speculative synthesis
    • Siesjo BK. 1981. Cell damage in the brain: A speculative synthesis. J Cereb Blood Flow Metab 1:155-185.
    • (1981) J Cereb Blood Flow Metab , vol.1 , pp. 155-185
    • Siesjo, B.K.1
  • 290
    • 0036175596 scopus 로고    scopus 로고
    • Mitochondrial contributions to tissue damage in stroke
    • Sims NR, Anderson MF. 2002. Mitochondrial contributions to tissue damage in stroke. Neurochem Int 40:511-526.
    • (2002) Neurochem Int , vol.40 , pp. 511-526
    • Sims, N.R.1    Anderson, M.F.2
  • 291
    • 0034967409 scopus 로고    scopus 로고
    • The immunophilin ligand FK506 attenuates axonal injury in an impact-acceleration model of traumatic brain injury
    • Singleton RH, Stone JR, Okonkwo DO, Pellicane AJ, Povlishock JT. 2001. The immunophilin ligand FK506 attenuates axonal injury in an impact-acceleration model of traumatic brain injury. J Neurotrauma 18:607-614.
    • (2001) J Neurotrauma , vol.18 , pp. 607-614
    • Singleton, R.H.1    Stone, J.R.2    Okonkwo, D.O.3    Pellicane, A.J.4    Povlishock, J.T.5
  • 292
    • 84965156221 scopus 로고
    • The effect of calcium on the respiratory and phosphorylative activities of heart-muscle sarcosomes
    • Slater EC, Cleland KW. 1953. The effect of calcium on the respiratory and phosphorylative activities of heart-muscle sarcosomes. Biochem J 55:566-590.
    • (1953) Biochem J , vol.55 , pp. 566-590
    • Slater, E.C.1    Cleland, K.W.2
  • 293
    • 0030695078 scopus 로고    scopus 로고
    • Progressive atrophy and neuron death for one year following brain trauma in the rat
    • Smith DH, Chen XH, Pierce JE, Wolf JA, Trojanowski JQ, et al. 1997. Progressive atrophy and neuron death for one year following brain trauma in the rat. J Neurotrauma 14:715-727.
    • (1997) J Neurotrauma , vol.14 , pp. 715-727
    • Smith, D.H.1    Chen, X.H.2    Pierce, J.E.3    Wolf, J.A.4    Trojanowski, J.Q.5
  • 294
    • 0026726556 scopus 로고
    • Protection by cyclosporin A of cultured hepatocytes from the toxic consequences of the loss of mitochondrial energization produced by 1-methyl-4-phenylpyridinium
    • Snyder JW, Pastorino JG, Attie AM, Farber JL. 1992. Protection by cyclosporin A of cultured hepatocytes from the toxic consequences of the loss of mitochondrial energization produced by 1-methyl-4-phenylpyridinium. Biochem Pharmacol 44:833-835.
    • (1992) Biochem Pharmacol , vol.44 , pp. 833-835
    • Snyder, J.W.1    Pastorino, J.G.2    Attie, A.M.3    Farber, J.L.4
  • 295
    • 0347124689 scopus 로고    scopus 로고
    • Nitricoxide-induced depolarization of neuronal mitochondria: Implications for neuronal cell death
    • Solenski NJ, Kostecki VK, Dovey S, Periasamy A. 2003. Nitricoxide-induced depolarization of neuronal mitochondria: Implications for neuronal cell death. Mol Cell Neurosci 24:1151-1169.
    • (2003) Mol Cell Neurosci , vol.24 , pp. 1151-1169
    • Solenski, N.J.1    Kostecki, V.K.2    Dovey, S.3    Periasamy, A.4
  • 296
    • 24144483470 scopus 로고    scopus 로고
    • 2+-induced mitochondrial oxidative stress and PC12 cell death
    • 2+-induced mitochondrial oxidative stress and PC12 cell death. Signal 7:1110-1116.
    • (2005) Signal , vol.7 , pp. 1110-1116
    • Sousa, S.C.1    Castilho, R.F.2
  • 297
    • 0037716926 scopus 로고    scopus 로고
    • 2+-induced oxidative stress in brain mitochondria treated with the respiratory chain inhibitor rotenone
    • 2+-induced oxidative stress in brain mitochondria treated with the respiratory chain inhibitor rotenone. FEBS Lett 543:179-183.
    • (2003) FEBS Lett , vol.543 , pp. 179-183
    • Sousa, S.C.1    Maciel, E.N.2    Vercesi, A.E.3    Castilho, R.F.4
  • 298
    • 12844260125 scopus 로고    scopus 로고
    • Octameric mitochondrial creatine kinase induces and stabilizes contact sites between the inner and outer membrane
    • Speer O, Back N, Buerklen T, Brdiczka D, Koretsky A, et al. 2005. Octameric mitochondrial creatine kinase induces and stabilizes contact sites between the inner and outer membrane. Biochem J 385:445-450.
    • (2005) Biochem J , vol.385 , pp. 445-450
    • Speer, O.1    Back, N.2    Buerklen, T.3    Brdiczka, D.4    Koretsky, A.5
  • 299
    • 26444489119 scopus 로고    scopus 로고
    • Connected to death: The (unexpurgated) mitochondrial pathway of apoptosis
    • Spierings D, McStay G, Saleh M, Bender C, Chipuk J, et al. 2005. Connected to death: The (unexpurgated) mitochondrial pathway of apoptosis. Science 310:66-67.
    • (2005) Science , vol.310 , pp. 66-67
    • Spierings, D.1    McStay, G.2    Saleh, M.3    Bender, C.4    Chipuk, J.5
  • 300
    • 3342910554 scopus 로고    scopus 로고
    • Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury
    • Starkov AA, Chinopoulos C, Fiskum G. 2004. Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury. Cell Calcium 36:257-264.
    • (2004) Cell Calcium , vol.36 , pp. 257-264
    • Starkov, A.A.1    Chinopoulos, C.2    Fiskum, G.3
  • 301
    • 0028235262 scopus 로고
    • 2+-dependent uncoupling and activation of external pathway of NADH oxidation are coupled to cyclosporin A-sensitive mitochondrial permeability transition
    • 2+-dependent uncoupling and activation of external pathway of NADH oxidation are coupled to cyclosporin A-sensitive mitochondrial permeability transition. Biochem Mol Biol Int 32:1147-1155.
    • (1994) Biochem Mol Biol Int , vol.32 , pp. 1147-1155
    • Starkov, A.A.1    Markova, O.V.2    Mokhova, E.N.3    Arrigoni-Martelli, E.4    Bobyleva, V.A.5
  • 302
    • 3242755831 scopus 로고    scopus 로고
    • Clinically approved heterocyclics act on a mitochondrial target and reduce stroke-induced pathology
    • Stavrovskaya IG, Narayanan MV, Zhang W, Krasnikov BF, Heemskerk J, et al. 2004. Clinically approved heterocyclics act on a mitochondrial target and reduce stroke-induced pathology. J Exp Med 200:211-222.
    • (2004) J Exp Med , vol.200 , pp. 211-222
    • Stavrovskaya, I.G.1    Narayanan, M.V.2    Zhang, W.3    Krasnikov, B.F.4    Heemskerk, J.5
  • 303
    • 0034619442 scopus 로고    scopus 로고
    • Dose-response curve and optimal dosing regimen of cyclosporin A after traumatic brain injury in rats
    • Sullivan PG, Rabchevsky AG, Hicks RR, Gibson TR, Fletcher-Turner A, et al. 2000. Dose-response curve and optimal dosing regimen of cyclosporin A after traumatic brain injury in rats. Neuroscience 101:289-295.
    • (2000) Neuroscience , vol.101 , pp. 289-295
    • Sullivan, P.G.1    Rabchevsky, A.G.2    Hicks, R.R.3    Gibson, T.R.4    Fletcher-Turner, A.5
  • 304
    • 12244281831 scopus 로고    scopus 로고
    • Mitochondrial permeability transition in CNS trauma: Cause or effect of neuronal cell death?
    • Sullivan PG, Rabchevsky AG, Waldmeier PC, Springer JE. 2005. Mitochondrial permeability transition in CNS trauma: Cause or effect of neuronal cell death? J Neurosci Res 79:231-239.
    • (2005) J Neurosci Res , vol.79 , pp. 231-239
    • Sullivan, P.G.1    Rabchevsky, A.G.2    Waldmeier, P.C.3    Springer, J.E.4
  • 305
    • 1842587600 scopus 로고    scopus 로고
    • Astrocyte influences on ischemic neuronal death
    • Swanson RA, Ying W, Kauppinen TM. 2004. Astrocyte influences on ischemic neuronal death. Curr Mol Med 4:193-205.
    • (2004) Curr Mol Med , vol.4 , pp. 193-205
    • Swanson, R.A.1    Ying, W.2    Kauppinen, T.M.3
  • 306
    • 0025905910 scopus 로고
    • The giant channel of the inner mitochondrial membrane is inhibited by cyclosporin A
    • Szabo I, Zoratti M. 1991. The giant channel of the inner mitochondrial membrane is inhibited by cyclosporin A. J Biol Chem 266:3376-3379.
    • (1991) J Biol Chem , vol.266 , pp. 3376-3379
    • Szabo, I.1    Zoratti, M.2
  • 307
    • 0027234336 scopus 로고
    • The mitochondrial permeability transition pore may comprise VDAC molecules. I. Binary structure and voltage dependence of the pore
    • Szabo I, Zoratti M. 1993. The mitochondrial permeability transition pore may comprise VDAC molecules. I. Binary structure and voltage dependence of the pore. FEBS Lett 330:201-205.
    • (1993) FEBS Lett , vol.330 , pp. 201-205
    • Szabo, I.1    Zoratti, M.2
  • 308
    • 0027236162 scopus 로고
    • The mitochondrial permeability transition pore may comprise VDAC molecules. II. The electrophysiological properties of VDAC are compatible with those of the mitochondrial megachannel
    • Szabo I, De Pinto V, Zoratti M. 1993. The mitochondrial permeability transition pore may comprise VDAC molecules. II. The electrophysiological properties of VDAC are compatible with those of the mitochondrial megachannel. FEBS Lett 330:206-210.
    • (1993) FEBS Lett , vol.330 , pp. 206-210
    • Szabo, I.1    De Pinto, V.2    Zoratti, M.3
  • 309
    • 12144290904 scopus 로고    scopus 로고
    • Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury
    • Teng YD, Choi H, Onario RC, Zhu S, Desilets FC, et al. 2004. Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury. Proc Natl Acad Sci USA 101:3071-3076.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 3071-3076
    • Teng, Y.D.1    Choi, H.2    Onario, R.C.3    Zhu, S.4    Desilets, F.C.5
  • 310
    • 16844369318 scopus 로고    scopus 로고
    • 2+ exchange are reduced in Alzheimer's disease cybrids
    • 2+ exchange are reduced in Alzheimer's disease cybrids. Mitochondrion 5:109-119.
    • (2005) Mitochondrion , vol.5 , pp. 109-119
    • Thiffault, C.1    Bennett Jr., J.P.2
  • 312
    • 0032561733 scopus 로고    scopus 로고
    • Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat
    • Uchino H, Elmer E, Uchino K, Li PA, He QP, et al. 1998. Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat. Brain Res 812:216-226.
    • (1998) Brain Res , vol.812 , pp. 216-226
    • Uchino, H.1    Elmer, E.2    Uchino, K.3    Li, P.A.4    He, Q.P.5
  • 313
    • 0029590050 scopus 로고
    • Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat
    • Uchino H, Elmer E, Uchino K, Lindvall O, Siesjo BK. 1995. Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat. Acta Physiol Scand 155:469-471.
    • (1995) Acta Physiol Scand , vol.155 , pp. 469-471
    • Uchino, H.1    Elmer, E.2    Uchino, K.3    Lindvall, O.4    Siesjo, B.K.5
  • 314
    • 0036403825 scopus 로고    scopus 로고
    • Differential neuroprotection by cyclosporin A and FK506 following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition
    • Uchino H, Minamikawa-Tachino R, Kristian T, Perkins G, Narazaki M, et al. 2002. Differential neuroprotection by cyclosporin A and FK506 following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition. Neurobiol Dis 10:219-233.
    • (2002) Neurobiol Dis , vol.10 , pp. 219-233
    • Uchino, H.1    Minamikawa-Tachino, R.2    Kristian, T.3    Perkins, G.4    Narazaki, M.5
  • 315
    • 0030565010 scopus 로고    scopus 로고
    • Ultrastructural morphological changes are not characteristic of apoptotic cell death following focal cerebral ischaemia in the rat
    • Van Lookeren Campagne M, Gill R. 1996. Ultrastructural morphological changes are not characteristic of apoptotic cell death following focal cerebral ischaemia in the rat. Neurosci Lett 21:111-114.
    • (1996) Neurosci Lett , vol.21 , pp. 111-114
    • Van Lookeren Campagne, M.1    Gill, R.2
  • 317
    • 1342305498 scopus 로고    scopus 로고
    • Study of PTPC composition during apoptosis for identification of viral protein target
    • Verrier F, Mignotte B, Jan G, Brenner C. 2003. Study of PTPC composition during apoptosis for identification of viral protein target. Ann N Y Acad Sci 1010:126-142.
    • (2003) Ann N Y Acad Sci , vol.1010 , pp. 126-142
    • Verrier, F.1    Mignotte, B.2    Jan, G.3    Brenner, C.4
  • 318
    • 1642524332 scopus 로고    scopus 로고
    • The intramitochondrial cytochrome c distribution varies correlated to the formation of a complex between VDAC and the adenine nucleotide translocase: This affects Bax-dependent cytochrome c release
    • Vyssokikh M, Zorova L, Zorov D, Heimlich G, Jurgensmeier J, et al. 2004. The intramitochondrial cytochrome c distribution varies correlated to the formation of a complex between VDAC and the adenine nucleotide translocase: This affects Bax-dependent cytochrome c release. Biochim Biophys Acta 1644:27-36.
    • (2004) Biochim Biophys Acta , vol.1644 , pp. 27-36
    • Vyssokikh, M.1    Zorova, L.2    Zorov, D.3    Heimlich, G.4    Jurgensmeier, J.5
  • 320
    • 10044224443 scopus 로고    scopus 로고
    • Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death
    • Wang H, Yu SW, Koh DW, Lew J, Coombs C, et al. 2004. Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death. J Neurosci 24:10963-10973.
    • (2004) J Neurosci , vol.24 , pp. 10963-10973
    • Wang, H.1    Yu, S.W.2    Koh, D.W.3    Lew, J.4    Coombs, C.5
  • 321
    • 4444351598 scopus 로고    scopus 로고
    • Necrosis, apoptosis, and hybrid death in the cortex and thalamus after barrel cortex ischemia in rats
    • Wei L, Ying DJ, Cui L, Langsdorf J, Yu SP. 2004. Necrosis, apoptosis, and hybrid death in the cortex and thalamus after barrel cortex ischemia in rats. Brain Res 1022:54-61.
    • (2004) Brain Res , vol.1022 , pp. 54-61
    • Wei, L.1    Ying, D.J.2    Cui, L.3    Langsdorf, J.4    Yu, S.P.5
  • 322
    • 0029788243 scopus 로고    scopus 로고
    • Mitochondrial depolarization in glutamate-stimulated neurons: An early signal specific to excitotoxin exposure
    • White RJ, Reynolds IJ. 1996. Mitochondrial depolarization in glutamate-stimulated neurons: An early signal specific to excitotoxin exposure. J Neurosci 16:5688-5697.
    • (1996) J Neurosci , vol.16 , pp. 5688-5697
    • White, R.J.1    Reynolds, I.J.2
  • 323
    • 0032570563 scopus 로고    scopus 로고
    • Fatty acid-induced uncoupling of oxidative phosphorylation is partly due to opening of the mitochondrial permeability transition pore
    • Wieckowski MR, Wojtczak L. 1998. Fatty acid-induced uncoupling of oxidative phosphorylation is partly due to opening of the mitochondrial permeability transition pore. FEBS Lett 423:339-342.
    • (1998) FEBS Lett , vol.423 , pp. 339-342
    • Wieckowski, M.R.1    Wojtczak, L.2
  • 324
    • 0034602536 scopus 로고    scopus 로고
    • Long-chain fatty acids promote opening of the reconstituted mitochondrial permeability transition pore
    • Wieckowski MR, Brdiczka D, Wojtczak L. 2000. Long-chain fatty acids promote opening of the reconstituted mitochondrial permeability transition pore. FEBS Lett 484:61-64.
    • (2000) FEBS Lett , vol.484 , pp. 61-64
    • Wieckowski, M.R.1    Brdiczka, D.2    Wojtczak, L.3
  • 325
    • 2442555970 scopus 로고    scopus 로고
    • The protein import machinery of mitochondria
    • Wiedemann N, Frazier AE, Pfanner N. 2004. The protein import machinery of mitochondria. J Biol Chem 279:14473-14476.
    • (2004) J Biol Chem , vol.279 , pp. 14473-14476
    • Wiedemann, N.1    Frazier, A.E.2    Pfanner, N.3
  • 326
    • 0022344980 scopus 로고
    • Hypoglycemia-induced neuronal damage prevented by an N-methyl-D-aspartate antagonist
    • Wieloch T. 1985. Hypoglycemia-induced neuronal damage prevented by an N-methyl-D-aspartate antagonist. Science 230:681-683.
    • (1985) Science , vol.230 , pp. 681-683
    • Wieloch, T.1
  • 327
    • 0001118297 scopus 로고
    • Formation and disappearance of an endogenous uncoupling factor during swelling and contraction of mitochondria
    • Wojtczak L, Lehninger AL. 1961. Formation and disappearance of an endogenous uncoupling factor during swelling and contraction of mitochondria. Biochim Biophys Acta 51:442-456.
    • (1961) Biochim Biophys Acta , vol.51 , pp. 442-456
    • Wojtczak, L.1    Lehninger, A.L.2
  • 328
    • 0344110248 scopus 로고    scopus 로고
    • Protonophoric activity of fatty acid analogs and derivatives in the inner mitochondrial membrane: A further argument for the fatty acid cycling model
    • Wojtczak L, Wieckowski MR, Schonfeld P. 1998. Protonophoric activity of fatty acid analogs and derivatives in the inner mitochondrial membrane: A further argument for the fatty acid cycling model. Arch Biochem Biophys 357:76-84.
    • (1998) Arch Biochem Biophys , vol.357 , pp. 76-84
    • Wojtczak, L.1    Wieckowski, M.R.2    Schonfeld, P.3
  • 329
    • 0032387842 scopus 로고    scopus 로고
    • Direct demonstration of a specific interaction between cyclophilin D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition
    • Woodfield K, Ruck A, Brdiczka D, Halestrap AP. 1998. Direct demonstration of a specific interaction between cyclophilin D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition. Biochem J 336(Pt 2):287-290.
    • (1998) Biochem J , vol.336 , Issue.PART 2 , pp. 287-290
    • Woodfield, K.1    Ruck, A.2    Brdiczka, D.3    Halestrap, A.P.4
  • 330
    • 0032765963 scopus 로고    scopus 로고
    • Mouse VDAC isoforms expressed in yeast: Channel properties and their roles in mitochondrial outer membrane permeability
    • Xu X, Decker W, Sampson MJ, Craigen WJ, Colombini M. 1999. Mouse VDAC isoforms expressed in yeast: Channel properties and their roles in mitochondrial outer membrane permeability. J Membr Biol 170:89-102.
    • (1999) J Membr Biol , vol.170 , pp. 89-102
    • Xu, X.1    Decker, W.2    Sampson, M.J.3    Craigen, W.J.4    Colombini, M.5
  • 331
    • 0033612939 scopus 로고    scopus 로고
    • Posttreatment with the immunosuppressant cyclosporin A in transient focal ischemia
    • Yoshimoto T, Siesjo BK. 1999. Posttreatment with the immunosuppressant cyclosporin A in transient focal ischemia. Brain Res 839:283-291.
    • (1999) Brain Res , vol.839 , pp. 283-291
    • Yoshimoto, T.1    Siesjo, B.K.2
  • 332
    • 0032442475 scopus 로고    scopus 로고
    • Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia
    • Yrjanheikki J, Keinanen R, Pellikka M, Hokfelt T, Koistinaho J. 1998. Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia. Proc Natl Acad Sci USA 95:15769-15774.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15769-15774
    • Yrjanheikki, J.1    Keinanen, R.2    Pellikka, M.3    Hokfelt, T.4    Koistinaho, J.5
  • 333
    • 0033539522 scopus 로고    scopus 로고
    • A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window
    • Yrjanheikki J, Tikka T, Keinanen R, Goldsteins G, Chan PH, et al. 1999. A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window. Proc Natl Acad Sci USA 96:13496-13500.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13496-13500
    • Yrjanheikki, J.1    Tikka, T.2    Keinanen, R.3    Goldsteins, G.4    Chan, P.H.5
  • 335
    • 1842636834 scopus 로고    scopus 로고
    • Adenine nucleotide translocase 3 (ANT3) overexpression induces apoptosis in cultured cells
    • Zamora M, Granell M, Mampel T, Vinas O. 2004. Adenine nucleotide translocase 3 (ANT3) overexpression induces apoptosis in cultured cells. FEBS Lett 563:155-160.
    • (2004) FEBS Lett , vol.563 , pp. 155-160
    • Zamora, M.1    Granell, M.2    Mampel, T.3    Vinas, O.4
  • 336
    • 0029101644 scopus 로고
    • Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death
    • Zamzami N, Marchetti P, Castedo M, Decaudin D, Macho A, et al. 1995a. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J Exp Med 182:367-377.
    • (1995) J Exp Med , vol.182 , pp. 367-377
    • Zamzami, N.1    Marchetti, P.2    Castedo, M.3    Decaudin, D.4    Macho, A.5
  • 338
    • 0029983059 scopus 로고    scopus 로고
    • Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis
    • Zamzami N, Marchetti P, Castedo M, Hirsch T, Susin SA, et al. 1996. Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis. FEBS Lett 384:53-57.
    • (1996) FEBS Lett , vol.384 , pp. 53-57
    • Zamzami, N.1    Marchetti, P.2    Castedo, M.3    Hirsch, T.4    Susin, S.A.5
  • 339
    • 0000713806 scopus 로고
    • Induction of swelling of liver mitochondria by fatty acids of various chain lengths
    • Zborowski J, Wojtczak L. 1963. Induction of swelling of liver mitochondria by fatty acids of various chain lengths. Biochim Biophys Acta 70:596-598.
    • (1963) Biochim Biophys Acta , vol.70 , pp. 596-598
    • Zborowski, J.1    Wojtczak, L.2
  • 340
    • 0037007645 scopus 로고    scopus 로고
    • Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice
    • Zhu S, Stavrovskaya IG, Drozda M, Kim BY, Ona V, et al. 2002. Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice. Nature 417:74-78.
    • (2002) Nature , vol.417 , pp. 74-78
    • Zhu, S.1    Stavrovskaya, I.G.2    Drozda, M.3    Kim, B.Y.4    Ona, V.5
  • 341
    • 0024554184 scopus 로고
    • Phenothiazines reduce ischemic damage to the central nervous system
    • Zivin JA, Kochhar A, Saitoh T. 1989. Phenothiazines reduce ischemic damage to the central nervous system. Brain Res 482:189-193.
    • (1989) Brain Res , vol.482 , pp. 189-193
    • Zivin, J.A.1    Kochhar, A.2    Saitoh, T.3
  • 342
    • 0028158479 scopus 로고
    • NADH regulates the gating of VDAC, the mitochondrial outer membrane channel
    • Zizi M, Forte M, Blachly-Dyson E, Colombini M. 1994. NADH regulates the gating of VDAC, the mitochondrial outer membrane channel. J Biol Chem 269:1614-1616.
    • (1994) J Biol Chem , vol.269 , pp. 1614-1616
    • Zizi, M.1    Forte, M.2    Blachly-Dyson, E.3    Colombini, M.4
  • 343
    • 0029116916 scopus 로고
    • The mitochondrial permeability transition
    • Zoratti M, Szabo I. 1995. The mitochondrial permeability transition. Biochim Biophys Acta 1241:139-176.
    • (1995) Biochim Biophys Acta , vol.1241 , pp. 139-176
    • Zoratti, M.1    Szabo, I.2
  • 344
    • 11144300815 scopus 로고    scopus 로고
    • Mitochondrial permeability transitions: How many doors to the house?
    • Zoratti M, Szabo I, De Marchi U. 2005. Mitochondrial permeability transitions: How many doors to the house? Biochim Biophys Acta 1706:40-52.
    • (2005) Biochim Biophys Acta , vol.1706 , pp. 40-52
    • Zoratti, M.1    Szabo, I.2    De Marchi, U.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.