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Volumn 16, Issue 6, 1999, Pages 511-521

Postinjury cyclosporin A administration limits axonal damage and disconnection in traumatic brain injury

Author keywords

Axonal injury; Calpain; Cylosporin A; Mitochondrial permeability transition; Trauma

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CALPAIN; CYCLOSPORIN A;

EID: 0345379310     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.1999.16.511     Document Type: Article
Times cited : (180)

References (36)
  • 1
    • 0032944441 scopus 로고    scopus 로고
    • The role of calpain-mediated spectrin proteolysis in traumatically induced axonal injury
    • BÜKI, A., SIMAN, R., TROJANOWSKY, J.Q., and POVLISHOCK, J.T. (1999). The role of calpain-mediated spectrin proteolysis in traumatically induced axonal injury. J Neuropathol. Exp. Neurol. 58, 365-375.
    • (1999) J Neuropathol. Exp. Neurol. , vol.58 , pp. 365-375
    • Büki, A.1    Siman, R.2    Trojanowsky, J.Q.3    Povlishock, J.T.4
  • 3
    • 0023686594 scopus 로고
    • Axonal damage in severe traumatic brain injury: An experimental study in cat
    • ERB, D.E., and POVLISHOCK, J.T. (1988). Axonal damage in severe traumatic brain injury: an experimental study in cat. Acta Neuropathol. 76, 347-358.
    • (1988) Acta Neuropathol. , vol.76 , pp. 347-358
    • Erb, D.E.1    Povlishock, J.T.2
  • 4
    • 0027386025 scopus 로고
    • A GTP-dependent step in the activation mechanism of capacitative calcium influx
    • FASOLATO, C., HOTH, M., and PENNER, R. (1993). A GTP-dependent step in the activation mechanism of capacitative calcium influx. J. Biol. Chem. 268, 20737-20740.
    • (1993) J. Biol. Chem. , vol.268 , pp. 20737-20740
    • Fasolato, C.1    Hoth, M.2    Penner, R.3
  • 5
    • 0028085099 scopus 로고
    • A new model of diffuse brain injury in rats. Part II. Morphological characterization
    • FODA, M.A.A.-E., and MARMAROU, A. (1994). A new model of diffuse brain injury in rats. Part II. Morphological characterization. J. Neurosurg. 80, 301-313.
    • (1994) J. Neurosurg. , vol.80 , pp. 301-313
    • Foda, M.A.A.-E.1    Marmarou, A.2
  • 6
    • 0030959940 scopus 로고    scopus 로고
    • Changes in the bioenergetic state of rat hippocampus during 2.5 min of ischemia, and prevention of cell damage by cyclosporin A in hyperglycemic subjects
    • FOLBERGROVA, J., LI, P.A., UCHINO, H., SMITH, M.L., and SIESJO, B.K. (1997). Changes in the bioenergetic state of rat hippocampus during 2.5 min of ischemia, and prevention of cell damage by cyclosporin A in hyperglycemic subjects. Exp. Brain Res. 114, 44-50.
    • (1997) Exp. Brain Res. , vol.114 , pp. 44-50
    • Folbergrova, J.1    Li, P.A.2    Uchino, H.3    Smith, M.L.4    Siesjo, B.K.5
  • 7
    • 0032528154 scopus 로고    scopus 로고
    • Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death
    • FRIBERG, H., FERRAND-DRAKE, M., BENGTSSON, F., HALESTRAP, A.P., and WIELOCH, T. (1998). Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death. J. Neurosci. 18, 5151-5159.
    • (1998) J. Neurosci. , vol.18 , pp. 5151-5159
    • Friberg, H.1    Ferrand-Drake, M.2    Bengtsson, F.3    Halestrap, A.P.4    Wieloch, T.5
  • 9
    • 0028168369 scopus 로고
    • 2+ influx dependent on store depletion by intracellular adenine-guanine nucleotide levels
    • 2+ influx dependent on store depletion by intracellular adenine-guanine nucleotide levels. J. Biol. Chem. 269, 23597-23602.
    • (1994) J. Biol. Chem. , vol.269 , pp. 23597-23602
    • Gamberucci, A.1    Innocenti, B.2    Fulceri, R.3
  • 10
    • 0027482350 scopus 로고
    • Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injury
    • GENTLEMAN, S.M., NASH, M.J., SWEETING, C.J., GRAHAM, D.I., and ROBERTS, G.W. (1993). Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injury. Neurosci. Lett. 160, 139-144.
    • (1993) Neurosci. Lett. , vol.160 , pp. 139-144
    • Gentleman, S.M.1    Nash, M.J.2    Sweeting, C.J.3    Graham, D.I.4    Roberts, G.W.5
  • 13
    • 0031843505 scopus 로고    scopus 로고
    • Post traumatic hypothermia protects against axonal damage in an animal model of traumatic axonal injury
    • KOIZUMI, H., and POVLISHOCK, J.T. (1998). Post traumatic hypothermia protects against axonal damage in an animal model of traumatic axonal injury. J. Neurosurg. 89, 303-309.
    • (1998) J. Neurosurg. , vol.89 , pp. 303-309
    • Koizumi, H.1    Povlishock, J.T.2
  • 14
    • 0023520075 scopus 로고
    • Monoclonal antibodies distinguish several differentially phosphorylated states of the two largest rat neurofilament subunits (NF-H and NF-M) and demonstrate their existence in the normal nervous system of adult rats
    • LEE, V.M., GARDEN, M.J., SCHLAEPFER, W.W., and TROJANOWSKI, J.Q. (1987). Monoclonal antibodies distinguish several differentially phosphorylated states of the two largest rat neurofilament subunits (NF-H and NF-M) and demonstrate their existence in the normal nervous system of adult rats. J. Neurosci. 7, 3474-3488.
    • (1987) J. Neurosci. , vol.7 , pp. 3474-3488
    • Lee, V.M.1    Garden, M.J.2    Schlaepfer, W.W.3    Trojanowski, J.Q.4
  • 16
    • 0030752893 scopus 로고    scopus 로고
    • A mechanistic analysis of nondisruptive axonal injury: A review
    • MAXWELL, W.L., POVLISHOCK, J.T., and GRAHAM, D.L. (1997). A mechanistic analysis of nondisruptive axonal injury: a review. J. Neurotrauma 14, 419-440.
    • (1997) J. Neurotrauma , vol.14 , pp. 419-440
    • Maxwell, W.L.1    Povlishock, J.T.2    Graham, D.L.3
  • 17
    • 0027234432 scopus 로고
    • Ultrastructural evidence of axonal shearing as a result of lateral accaleration of the head in non-human primates
    • MAXWELL, W.L., WATT, C., GRAHAM, D.I., and GENNARELLI, T. A. (1993). Ultrastructural evidence of axonal shearing as a result of lateral accaleration of the head in non-human primates. Acta Neuropathol. 86, 136-144.
    • (1993) Acta Neuropathol. , vol.86 , pp. 136-144
    • Maxwell, W.L.1    Watt, C.2    Graham, D.I.3    Gennarelli, T.A.4
  • 18
    • 0032536329 scopus 로고    scopus 로고
    • Alteration of the neurofilament sidearm and its relation to neurofilament compaction occurring with traumatic axonal injury
    • OKONKWO, D.O., PETTUS, E.H., MOROI, J., POVLISHOCK, J.T. (1998). Alteration of the neurofilament sidearm and its relation to neurofilament compaction occurring with traumatic axonal injury. Brain Res. 78, 1-6.
    • (1998) Brain Res. , vol.78 , pp. 1-6
    • Okonkwo, D.O.1    Pettus, E.H.2    Moroi, J.3    Povlishock, J.T.4
  • 19
    • 0033525008 scopus 로고    scopus 로고
    • Cyclosporin A limits calcium-induced axonal damage following traumatic brain injury
    • OKONKWO, D.O., BÜKI, A., SIMAN, R., and POVLISHOCK, J.T. (1999). Cyclosporin A limits calcium-induced axonal damage following traumatic brain injury. Neuroreport 10, 353-358.
    • (1999) Neuroreport , vol.10 , pp. 353-358
    • Okonkwo, D.O.1    Büki, A.2    Siman, R.3    Povlishock, J.T.4
  • 20
    • 0033509493 scopus 로고    scopus 로고
    • A single intrathecal bolus of cyclosporin A before injury preserves mitochondrial integrity and attenuates axonal disruption following traumatic brain injury
    • OKONKWO, D.O., and POVLISHOCK, J.T. (1999). A single intrathecal bolus of cyclosporin A before injury preserves mitochondrial integrity and attenuates axonal disruption following traumatic brain injury. J. Cereb. Blood Flow Metab 19, 443-451.
    • (1999) J. Cereb. Blood Flow Metab , vol.19 , pp. 443-451
    • Okonkwo, D.O.1    Povlishock, J.T.2
  • 21
    • 0028152764 scopus 로고
    • Traumatically induced altered membrane permeability: Its relationship to traumatically induced reactive axonal change
    • PETTUS, E.H., CHRISTMAN, C.W., GIEBEL, M.L., and POVLISHOCK, J.T. (1994). Traumatically induced altered membrane permeability: its relationship to traumatically induced reactive axonal change. J. Neurotrauma 11, 507-522.
    • (1994) J. Neurotrauma , vol.11 , pp. 507-522
    • Pettus, E.H.1    Christman, C.W.2    Giebel, M.L.3    Povlishock, J.T.4
  • 22
    • 0029896102 scopus 로고    scopus 로고
    • Characterization of a distinct set of intra-axonal ultrastructural changes associated with traumatically induced alteration in axolemmal permeability
    • PETTUS, E.H., and POVLISHOCK, J.T. (1996). Characterization of a distinct set of intra-axonal ultrastructural changes associated with traumatically induced alteration in axolemmal permeability. Brain Res. 722, 1-11.
    • (1996) Brain Res. , vol.722 , pp. 1-11
    • Pettus, E.H.1    Povlishock, J.T.2
  • 24
    • 0030725073 scopus 로고    scopus 로고
    • Impact acceleration injury in the rat: Evidence for focal axolemmal change and related neurofilament sidearm alteration
    • POVLISHOCK, J.T., MARMAROU, A., MCINTOSH, T., TROJANOWSKI, J.Q., and MOROI, J. (1997). Impact acceleration injury in the rat: evidence for focal axolemmal change and related neurofilament sidearm alteration. J. neuropathol. Exp. Neurol. 56, 347-359.
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 347-359
    • Povlishock, J.T.1    Marmarou, A.2    McIntosh, T.3    Trojanowski, J.Q.4    Moroi, J.5
  • 25
    • 0029691406 scopus 로고    scopus 로고
    • Traumatically induced axonal damage: Evidence for enduring changes in axolemmal permeability with associated cytoskeletal change
    • POVLISHOCK, J.T., and PETTUS, E.H. (1996). Traumatically induced axonal damage: evidence for enduring changes in axolemmal permeability with associated cytoskeletal change. Acta Neurochir. Suppl. (Wien) 66, 81-86.
    • (1996) Acta Neurochir. Suppl. (Wien) , vol.66 , pp. 81-86
    • Povlishock, J.T.1    Pettus, E.H.2
  • 26
    • 0028282502 scopus 로고
    • Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain
    • ROBERTS-LEWIS, J.M., SAVAGE, M.J., MARCY, V.R., PINSKER, L.R., and SIMAN, R. (1994). Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain. J. Neurosci. 14, 3934-3944.
    • (1994) J. Neurosci. , vol.14 , pp. 3934-3944
    • Roberts-Lewis, J.M.1    Savage, M.J.2    Marcy, V.R.3    Pinsker, L.R.4    Siman, R.5
  • 27
    • 0031243290 scopus 로고    scopus 로고
    • Neural roles of immunophilins and their ligands
    • SABATINI, D.M., LAI, M.M., and SNYDER, S.H. (1997). Neural roles of immunophilins and their ligands. Mol. Neurobiol. 15, 223-239.
    • (1997) Mol. Neurobiol. , vol.15 , pp. 223-239
    • Sabatini, D.M.1    Lai, M.M.2    Snyder, S.H.3
  • 28
    • 0026446691 scopus 로고
    • Cyclosporin A protects against ischemia-reperfusion injury in the brain
    • SHIGA, Y., ONODERA, H., MATSUO, Y., and KOGURE, K. (1992). Cyclosporin A protects against ischemia-reperfusion injury in the brain. Brain Res. 595, 145-148.
    • (1992) Brain Res. , vol.595 , pp. 145-148
    • Shiga, Y.1    Onodera, H.2    Matsuo, Y.3    Kogure, K.4
  • 29
    • 0021273261 scopus 로고
    • Brain fodrin: Substrate for calpain I, an endogenous calcium-activated protease
    • SIMAN, R., BAUDRY, M., and LYNCH, G. (1984). Brain fodrin: substrate for calpain I, an endogenous calcium-activated protease. Proc. Natl. Acad. Sci. U.S.A. 81, 3572-3576.
    • (1984) Proc. Natl. Acad. Sci. U.S.A. , vol.81 , pp. 3572-3576
    • Siman, R.1    Baudry, M.2    Lynch, G.3
  • 30
    • 0024363137 scopus 로고
    • Calpain 1 activation is specifically related to excitatory amino acid induction of hippocampal damage
    • SIMAN, R., NOSZEK, J.C., and KEGERISE, C. (1989). Calpain 1 activation is specifically related to excitatory amino acid induction of hippocampal damage. J. Neurosci. 9, 1579-1590.
    • (1989) J. Neurosci. , vol.9 , pp. 1579-1590
    • Siman, R.1    Noszek, J.C.2    Kegerise, C.3
  • 31
    • 0029952158 scopus 로고    scopus 로고
    • Mechanisms of secondary brain injury
    • SIESJO, B.K., and SIESJO, P. (1996). Mechanisms of secondary brain injury. Eur. J. Anaesthesiol. 13, 247-268.
    • (1996) Eur. J. Anaesthesiol. , vol.13 , pp. 247-268
    • Siesjo, B.K.1    Siesjo, P.2
  • 32
    • 0033010343 scopus 로고    scopus 로고
    • The EM visualization of antibodies targeted to amyloid precursor proteins in axons undergoing traumatically induced reactive change
    • STONE, J.P., CHRISTMAN, C.W., and POVLISHOCK, J.T. (1999). The EM visualization of antibodies targeted to amyloid precursor proteins in axons undergoing traumatically induced reactive change. Acta Neuropathol. 97, 335-345.
    • (1999) Acta Neuropathol. , vol.97 , pp. 335-345
    • Stone, J.P.1    Christman, C.W.2    Povlishock, J.T.3
  • 33
    • 0031029081 scopus 로고    scopus 로고
    • Inhibition of the electrogenic Na pump underlies delayed depolarization of cortical neurons after mechanical injury or glutamate
    • TAVALIN, S.J., ELLIS, E.F., and SATIN, L.S. (1997). Inhibition of the electrogenic Na pump underlies delayed depolarization of cortical neurons after mechanical injury or glutamate J. Neurophysiol. 77, 632-638.
    • (1997) J. Neurophysiol. , vol.77 , pp. 632-638
    • Tavalin, S.J.1    Ellis, E.F.2    Satin, L.S.3
  • 34
    • 0029590050 scopus 로고
    • Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischemia in the rat
    • UCHINO, H., ELMER, E., UCHINO, K., LINDVALL, O., and SIESJO, B.K. (1995). Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischemia in the rat. Acta Physiol. Scand. 155, 469-471.
    • (1995) Acta Physiol. Scand. , vol.155 , pp. 469-471
    • Uchino, H.1    Elmer, E.2    Uchino, K.3    Lindvall, O.4    Siesjo, B.K.5
  • 35
    • 0022518521 scopus 로고
    • Spectrin subtypes in mammalian brain: An immunoelectron microscopic study
    • ZAGON, I.S., HIGBEE, R., RIEDERER, B.M., and GOODMAN, S.R. (1986). Spectrin subtypes in mammalian brain: an immunoelectron microscopic study. J. Neurosci. 6, 2977-2986.
    • (1986) J. Neurosci. , vol.6 , pp. 2977-2986
    • Zagon, I.S.1    Higbee, R.2    Riederer, B.M.3    Goodman, S.R.4
  • 36
    • 0029116916 scopus 로고
    • The mitochondrial permeability transition
    • ZORATTI, M., and SZABO, I. (1995). The mitochondrial permeability transition. Biochim. Biophys. Acta 1241, 139-176.
    • (1995) Biochim. Biophys. Acta , vol.1241 , pp. 139-176
    • Zoratti, M.1    Szabo, I.2


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