메뉴 건너뛰기




Volumn 23, Issue 4, 2000, Pages 166-174

Mitochondrial membrane potential and neuronal glutamate excitotoxicity: Mortality and millivolts

Author keywords

[No Author keywords available]

Indexed keywords

EXCITOTOXIN; FLUORESCENT DYE; GLUTAMIC ACID; OLIGOMYCIN; RHODAMINE; RHODAMINE 123;

EID: 0034176843     PISSN: 01662236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-2236(99)01534-9     Document Type: Review
Times cited : (499)

References (101)
  • 1
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: An integrated view
    • Dirnagl, U. et al. (1999) Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci. 22, 391-397
    • (1999) Trends Neurosci. , vol.22 , pp. 391-397
    • Dirnagl, U.1
  • 2
    • 0033600277 scopus 로고    scopus 로고
    • The changing landscape of ischaemic brain injury mechanisms
    • Lee, J.M. et al. (1999) The changing landscape of ischaemic brain injury mechanisms. Nature 399, A7-A14
    • (1999) Nature , vol.399
    • Lee, J.M.1
  • 3
    • 0032504708 scopus 로고    scopus 로고
    • Mitochondria and neuronal glutamate excitotoxicity
    • Nicholls, D.G. and Budd, S.L. (1998) Mitochondria and neuronal glutamate excitotoxicity. Biochim. Biophys. Acta 1366, 97-112
    • (1998) Biochim. Biophys. Acta , vol.1366 , pp. 97-112
    • Nicholls, D.G.1    Budd, S.L.2
  • 5
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
    • Ankarcrona, M. et al. (1995) Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15, 961-973
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarcrona, M.1
  • 6
    • 0029788243 scopus 로고    scopus 로고
    • Mitochondrial depolarization in glutamate-stimulated neurons: An early signal specific to excitotoxin exposure
    • White, R.J. and Reynolds, I.J. (1996) Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure. J. Neurosci. 16, 5688-5697
    • (1996) J. Neurosci. , vol.16 , pp. 5688-5697
    • White, R.J.1    Reynolds, I.J.2
  • 7
    • 0029810095 scopus 로고    scopus 로고
    • Mitochondrial dysfunction is a primary event in glutamate excitotoxicity
    • Schinder, A.F. et al. (1996) Mitochondrial dysfunction is a primary event in glutamate excitotoxicity. J. Neurosci. 16, 6125-6133
    • (1996) J. Neurosci. , vol.16 , pp. 6125-6133
    • Schinder, A.F.1
  • 8
    • 0030592838 scopus 로고    scopus 로고
    • Mitochondrial deenergization underlies neuronal calcium overload following a prolonged glutamate challenge
    • Khodorov, B.I. et al. (1996) Mitochondrial deenergization underlies neuronal calcium overload following a prolonged glutamate challenge. FEBS Lett. 397, 230-234
    • (1996) FEBS Lett. , vol.397 , pp. 230-234
    • Khodorov, B.I.1
  • 9
    • 0030603110 scopus 로고    scopus 로고
    • 2+-dependent collapse of mitochondrial membrane potential and ultrastructural alterations of mitochondria
    • 2+-dependent collapse of mitochondrial membrane potential and ultrastructural alterations of mitochondria. FEBS Lett. 392, 143-147
    • (1996) FEBS Lett. , vol.392 , pp. 143-147
    • Isaev, N.K.1
  • 10
    • 0032529841 scopus 로고    scopus 로고
    • 2+ signaling and mitochondrial deficiencies in hippocampal neurons of trisomy 16 mice: A model of Down's syndrome
    • 2+ signaling and mitochondrial deficiencies in hippocampal neurons of trisomy 16 mice: a model of Down's syndrome. J. Neurosci. 18, 7216-7231
    • (1998) J. Neurosci. , vol.18 , pp. 7216-7231
    • Schuchmann, S.1
  • 11
    • 0031797319 scopus 로고    scopus 로고
    • Effects of oxidants and glutamate receptor activation on mitochondrial membrane potential in rat forebrain neurons
    • Scanlon, J.M. and Reynolds, I.J. (1998) Effects of oxidants and glutamate receptor activation on mitochondrial membrane potential in rat forebrain neurons. J. Neurochem. 71, 2392-2400
    • (1998) J. Neurochem. , vol.71 , pp. 2392-2400
    • Scanlon, J.M.1    Reynolds, I.J.2
  • 12
    • 0031891837 scopus 로고    scopus 로고
    • Mitochondrial transmembrane potential and free radical production in excitotoxic neurodegeneration
    • Prehn, J.H.M. (1998) Mitochondrial transmembrane potential and free radical production in excitotoxic neurodegeneration. Naunyn-Schmiedeberg's Arch. Pharmacol. 357, 316-322
    • (1998) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.357 , pp. 316-322
    • Prehn, J.H.M.1
  • 13
    • 0031818025 scopus 로고    scopus 로고
    • The difference between mechanisms of kainate and glutamate excitotoxicity in vitro: Osmotic lesion versus mitochondrial depolarization
    • Kiedrowski, L. (1998) The difference between mechanisms of kainate and glutamate excitotoxicity in vitro: osmotic lesion versus mitochondrial depolarization. Restor. Neurol. Neurosci. 12, 71-79
    • (1998) Restor. Neurol. Neurosci. , vol.12 , pp. 71-79
    • Kiedrowski, L.1
  • 14
    • 0033118649 scopus 로고    scopus 로고
    • Contributions of mitochondria to animal physiology: From homeostatic sensor to calcium signalling and cell death
    • Duchen, M.R. (1999) Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death. J. Physiol. 516, 1-17
    • (1999) J. Physiol. , vol.516 , pp. 1-17
    • Duchen, M.R.1
  • 15
    • 0033016172 scopus 로고    scopus 로고
    • Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice
    • Guo, Q. et al. (1999) Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice. Nat. Med. 5, 101-106
    • (1999) Nat. Med. , vol.5 , pp. 101-106
    • Guo, Q.1
  • 16
    • 0344224265 scopus 로고    scopus 로고
    • Nitric oxide mediates glutamate induced mitochondrial depolarization in rat cortical neurons
    • Almeida, A. et al. (1999) Nitric oxide mediates glutamate induced mitochondrial depolarization in rat cortical neurons. Brain Res. 816, 580-586
    • (1999) Brain Res. , vol.816 , pp. 580-586
    • Almeida, A.1
  • 17
    • 0026608995 scopus 로고
    • Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons
    • Randall, R.D. and Thayer, S.A. (1992) Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons. J. Neurosci. 12, 1882-1895
    • (1992) J. Neurosci. , vol.12 , pp. 1882-1895
    • Randall, R.D.1    Thayer, S.A.2
  • 18
    • 0027497936 scopus 로고
    • Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons
    • Tymianski, M. et al. (1993) Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons. J. Neurosci. 13, 2085-2104
    • (1993) J. Neurosci. , vol.13 , pp. 2085-2104
    • Tymianski, M.1
  • 19
    • 0029827804 scopus 로고    scopus 로고
    • Mitochondrial calcium regulation and acute glutamate excitotoxicity in cultured cerebellar granule cells
    • Budd, S.L. and Nicholls, D.G. (1996) Mitochondrial calcium regulation and acute glutamate excitotoxicity in cultured cerebellar granule cells. J. Neurochem. 67, 2282-2291
    • (1996) J. Neurochem. , vol.67 , pp. 2282-2291
    • Budd, S.L.1    Nicholls, D.G.2
  • 20
    • 0028126999 scopus 로고
    • Glutamate-induced intracellular calcium changes and neurotoxicity in cortical neurons in vitro: Effect of chemical ischemia
    • Rajdev, S. and Reynolds, I.J. (1994) Glutamate-induced intracellular calcium changes and neurotoxicity in cortical neurons in vitro: effect of chemical ischemia. Neuroscience 62, 667-679
    • (1994) Neuroscience , vol.62 , pp. 667-679
    • Rajdev, S.1    Reynolds, I.J.2
  • 21
    • 0033971898 scopus 로고    scopus 로고
    • Mitochondria and neuronal survival
    • Nicholls, D.G. and Budd, S.L. (2000) Mitochondria and neuronal survival. Physiol. Rev. 80, 315-360
    • (2000) Physiol. Rev. , vol.80 , pp. 315-360
    • Nicholls, D.G.1    Budd, S.L.2
  • 22
    • 0029691578 scopus 로고    scopus 로고
    • Cytosolic calcium concentrations and cell death in vitro
    • Tymianski, M. (1996) Cytosolic calcium concentrations and cell death in vitro. Adv. Neurol. 71, 85-105
    • (1996) Adv. Neurol. , vol.71 , pp. 85-105
    • Tymianski, M.1
  • 23
    • 0028985491 scopus 로고
    • 2+ exchange buffer glutamate-induced calcium loads in cultured cortical neurons
    • 2+ exchange buffer glutamate-induced calcium loads in cultured cortical neurons. J. Neurosci. 15, 1318-1328
    • (1995) J. Neurosci. , vol.15 , pp. 1318-1328
    • White, R.J.1    Reynolds, I.J.2
  • 24
    • 0028842324 scopus 로고
    • Glutamate-induced destabilization of intracellular calcium concentration homeostasis in cultured cerebellar granule cells: Role of mitochondria in calcium buffering
    • Kiedrowski, L. and Costa, E. (1995) Glutamate-induced destabilization of intracellular calcium concentration homeostasis in cultured cerebellar granule cells: role of mitochondria in calcium buffering. Mol. Pharmacol. 47, 140-147
    • (1995) Mol. Pharmacol. , vol.47 , pp. 140-147
    • Kiedrowski, L.1    Costa, E.2
  • 25
    • 0000434165 scopus 로고    scopus 로고
    • 2+ loads by mitochondria in cultured rat hippocampal neurons
    • 2+ loads by mitochondria in cultured rat hippocampal neurons. J. Neurophysiol. 76, 1611-1621
    • (1996) J. Neurophysiol. , vol.76 , pp. 1611-1621
    • Wang, G.J.1    Thayer, S.A.2
  • 26
    • 0030576914 scopus 로고    scopus 로고
    • Dominant role of mitochondria in protection against a delayed neuronal Ca overload induced by endogenous excitatory amino acids following a glutamate pulse
    • Khodorov, B.I. et al. (1996) Dominant role of mitochondria in protection against a delayed neuronal Ca overload induced by endogenous excitatory amino acids following a glutamate pulse. FEBS Lett. 393, 135-138
    • (1996) FEBS Lett. , vol.393 , pp. 135-138
    • Khodorov, B.I.1
  • 27
    • 0032535275 scopus 로고    scopus 로고
    • Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells
    • Castilho, R.F. et al. (1998) Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells. J. Neurosci. 18, 10277-10286
    • (1998) J. Neurosci. , vol.18 , pp. 10277-10286
    • Castilho, R.F.1
  • 28
    • 0031016799 scopus 로고    scopus 로고
    • 2+ following intense glutamate stimulation of cultured rat forebrain neurones
    • 2+ following intense glutamate stimulation of cultured rat forebrain neurones. J. Physiol. 498, 31-47
    • (1997) J. Physiol. , vol.498 , pp. 31-47
    • White, R.J.1    Reynolds, I.J.2
  • 29
    • 0033061920 scopus 로고    scopus 로고
    • Oxidative stress, mitochondrial function and acute glutamate excitotoxicity in cultured cerebellar granule cells
    • Castilho, R.F. and Nicholls, D.G. (1999) Oxidative stress, mitochondrial function and acute glutamate excitotoxicity in cultured cerebellar granule cells. J. Neurochem. 72, 1394-1401
    • (1999) J. Neurochem. , vol.72 , pp. 1394-1401
    • Castilho, R.F.1    Nicholls, D.G.2
  • 30
    • 0031839233 scopus 로고    scopus 로고
    • Privileged access to mitochondria of calcium influx through N-methyl-D-aspartate receptors
    • Peng, T.I. and Greenamyre, J.T. (1998) Privileged access to mitochondria of calcium influx through N-methyl-D-aspartate receptors. Mol. Pharmacol. 53, 974-980
    • (1998) Mol. Pharmacol. , vol.53 , pp. 974-980
    • Peng, T.I.1    Greenamyre, J.T.2
  • 31
    • 0018269944 scopus 로고
    • The regulation of extra-mitochondrial free Ca by rat liver mitochondria
    • Nicholls, D.G. (1978) The regulation of extra-mitochondrial free Ca by rat liver mitochondria. Biochem. J. 176, 463-474
    • (1978) Biochem. J. , vol.176 , pp. 463-474
    • Nicholls, D.G.1
  • 32
    • 0029998621 scopus 로고    scopus 로고
    • The permeability transition pore as a mitochondrial calcium release channel: A critical appraisal
    • Bernardi, P. and Petronilli, V. (1996) The permeability transition pore as a mitochondrial calcium release channel: a critical appraisal. J. Bioenerg. Biomembr. 28, 131-138
    • (1996) J. Bioenerg. Biomembr. , vol.28 , pp. 131-138
    • Bernardi, P.1    Petronilli, V.2
  • 33
    • 0029116916 scopus 로고
    • The mitochondrial permeability transition
    • Zoratti, M. and Szabo, I. (1995) The mitochondrial permeability transition. Biochim. Biophys. Acta 1241, 139-176
    • (1995) Biochim. Biophys. Acta , vol.1241 , pp. 139-176
    • Zoratti, M.1    Szabo, I.2
  • 34
    • 0032021067 scopus 로고    scopus 로고
    • 2+ regulation in neuronal and glial cell signalling
    • 2+ regulation in neuronal and glial cell signalling. Brain Res. Rev. 26, 72-81
    • (1998) Brain Res. Rev. , vol.26 , pp. 72-81
    • Simpson, P.B.1    Russell, J.T.2
  • 35
    • 0032530326 scopus 로고    scopus 로고
    • Calcium-induced activation of the mitochondrial permeability transition in hippocampal neurons
    • Dubinsky, J.M. and Levi, Y. (1998) Calcium-induced activation of the mitochondrial permeability transition in hippocampal neurons. J. Neurosci. Res. 53, 728-741
    • (1998) J. Neurosci. Res. , vol.53 , pp. 728-741
    • Dubinsky, J.M.1    Levi, Y.2
  • 36
    • 0031698036 scopus 로고    scopus 로고
    • 2+-dependent damage of cultured cerebellar granule cells
    • 2+-dependent damage of cultured cerebellar granule cells. FEBS Lett. 434, 188-192
    • (1998) FEBS Lett. , vol.434 , pp. 188-192
    • Isaev, N.K.1
  • 37
    • 0030298459 scopus 로고    scopus 로고
    • Cyclosporin a delays mitochondrial depolarization induced by N-methyl-D-aspartate in cortical neurons: Evidence of the mitochondrial permeability transition
    • Nieminen, A.L. et al. (1996) Cyclosporin a delays mitochondrial depolarization induced by N-methyl-D-aspartate in cortical neurons: evidence of the mitochondrial permeability transition. Neuroscience 75, 993-997
    • (1996) Neuroscience , vol.75 , pp. 993-997
    • Nieminen, A.L.1
  • 38
    • 0033199019 scopus 로고    scopus 로고
    • Glutamate-induced mitochondrial depolarization and perturbation of calcium homeostasis in cultured rat hippocampal neurones
    • Vergun, O. et al. (1999) Glutamate-induced mitochondrial depolarization and perturbation of calcium homeostasis in cultured rat hippocampal neurones. J. Physiol. 519, 451-466
    • (1999) J. Physiol. , vol.519 , pp. 451-466
    • Vergun, O.1
  • 39
    • 0017373769 scopus 로고
    • Inter-relationships between proton electrochemical gradient, adenine nucleotide phosphorylation potential and respiration during substrate-level and oxidative phosphorylation by mitochondria from brown adipose tissue of cold-adapted guinea-pigs
    • Nicholls, D.G. and Bernson, V.S.M. (1977) Inter-relationships between proton electrochemical gradient, adenine nucleotide phosphorylation potential and respiration during substrate-level and oxidative phosphorylation by mitochondria from brown adipose tissue of cold-adapted guinea-pigs. Eur. J. Biochem. 75, 601-612
    • (1977) Eur. J. Biochem. , vol.75 , pp. 601-612
    • Nicholls, D.G.1    Bernson, V.S.M.2
  • 40
    • 0029765443 scopus 로고    scopus 로고
    • Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants
    • Skulachev, V.P. (1996) Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants. Q. Rev. Biophys. 29, 169-202
    • (1996) Q. Rev. Biophys. , vol.29 , pp. 169-202
    • Skulachev, V.P.1
  • 41
    • 0030615104 scopus 로고    scopus 로고
    • 2 formation by rat heart mitochondria on substrate availability and donor age
    • 2 formation by rat heart mitochondria on substrate availability and donor age. J. Bioenerg. Biomembr. 29, 89-95
    • (1997) J. Bioenerg. Biomembr. , vol.29 , pp. 89-95
    • Hansford, R.G.1
  • 42
    • 0038061012 scopus 로고    scopus 로고
    • Role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation
    • Nègre-Salvayre, A. et al. (1997) Role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation. FASEB J. 11, 809-815
    • (1997) FASEB J. , vol.11 , pp. 809-815
    • Nègre-Salvayre, A.1
  • 43
    • 0027933701 scopus 로고
    • +: Implications for neurodegeneration
    • +: implications for neurodegeneration. J. Neurochem. 63, 584-591
    • (1994) J. Neurochem. , vol.63 , pp. 584-591
    • Dykens, J.A.1
  • 44
    • 0028821028 scopus 로고
    • 2+-induced mitochondrial membrane permeabilization: Role of coenzyme Q redox state
    • 2+-induced mitochondrial membrane permeabilization: role of coenzyme Q redox state. Am. J. Physiol. 269, C141-C147
    • (1995) Am. J. Physiol. , vol.269
    • Kowaltowski, A.J.1
  • 45
    • 0028882764 scopus 로고
    • Mitochondrial production of reactive oxygen species in cortical neurons following exposure to NMDA
    • Dugan, L.L. et al. (1995) Mitochondrial production of reactive oxygen species in cortical neurons following exposure to NMDA. J. Neurosci. 15, 6377-6388
    • (1995) J. Neurosci. , vol.15 , pp. 6377-6388
    • Dugan, L.L.1
  • 46
    • 0029064518 scopus 로고
    • Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation
    • Reynolds, I.J. and Hastings, T.G. (1995) Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. J. Neurosci. 15, 3318-3327
    • (1995) J. Neurosci. , vol.15 , pp. 3318-3327
    • Reynolds, I.J.1    Hastings, T.G.2
  • 47
    • 0030008052 scopus 로고    scopus 로고
    • Superoxide production in rat hippocampal neurons: Selective imaging with hydroethidine
    • Bindokas, V.P. et al. (1996) Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine. J. Neurosci. 16, 1324-1336
    • (1996) J. Neurosci. , vol.16 , pp. 1324-1336
    • Bindokas, V.P.1
  • 48
    • 0000236120 scopus 로고    scopus 로고
    • In vitro ischemia promotes glutamate-mediated free radical generation and intracellular calcium accumulation in hippocampal pyramidal neurons
    • Velazquez, J.L.P. et al. (1997) In vitro ischemia promotes glutamate-mediated free radical generation and intracellular calcium accumulation in hippocampal pyramidal neurons. J. Neurosci. 17, 9085-9094
    • (1997) J. Neurosci. , vol.17 , pp. 9085-9094
    • Velazquez, J.L.P.1
  • 49
    • 0031869004 scopus 로고    scopus 로고
    • NMDA-induced Superoxide production and neurotoxicity in cultured rat hippocampal neurons: Role of mitochondria
    • Sengpiel, B. et al. (1998) NMDA-induced Superoxide production and neurotoxicity in cultured rat hippocampal neurons: role of mitochondria. Eur. J. Neurosci. 10, 1903-1910
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 1903-1910
    • Sengpiel, B.1
  • 50
    • 0033574169 scopus 로고    scopus 로고
    • Sources of reactive oxygen species production in excitotoxin-stimulated cerebellar granule cells
    • Boldyrev, A.A. et al. (1999) Sources of reactive oxygen species production in excitotoxin-stimulated cerebellar granule cells. Biochem. Biophys. Res. Commun. 256, 320-324
    • (1999) Biochem. Biophys. Res. Commun. , vol.256 , pp. 320-324
    • Boldyrev, A.A.1
  • 51
    • 0032150860 scopus 로고    scopus 로고
    • Glutamate-induced neuron death requires mitochondrial calcium uptake
    • Stout, A.K. et al. (1998) Glutamate-induced neuron death requires mitochondrial calcium uptake. Nat. Neurosci. 1, 366-373
    • (1998) Nat. Neurosci. , vol.1 , pp. 366-373
    • Stout, A.K.1
  • 52
    • 0033609791 scopus 로고    scopus 로고
    • TM) induces the mitochondrial permeability transition and inhibits respiratory complex I: Implications for the mechanism of cytochrome c release
    • TM) induces the mitochondrial permeability transition and inhibits respiratory complex I: implications for the mechanism of cytochrome c release. J. Biol. Chem. 274, 24657-24663
    • (1999) J. Biol. Chem. , vol.274 , pp. 24657-24663
    • Scorrano, L.1
  • 53
    • 0031601257 scopus 로고    scopus 로고
    • Is chloromethyl-X-rosamine useful in measuring mitochondrial transmembrane potential?
    • Ferlini, C. et al. (1998) Is chloromethyl-X-rosamine useful in measuring mitochondrial transmembrane potential? Cytometry 31, 74-75
    • (1998) Cytometry , vol.31 , pp. 74-75
    • Ferlini, C.1
  • 54
    • 0029966796 scopus 로고    scopus 로고
    • Chloromethyl-X-rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis
    • Macho, A. et al. (1996) Chloromethyl-X-rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis. Cytometry 25, 333-340
    • (1996) Cytometry , vol.25 , pp. 333-340
    • Macho, A.1
  • 55
    • 0032472329 scopus 로고    scopus 로고
    • Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
    • Bossy-Wetzel, E. et al. (1998) Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization. EMBO J. 17, 37-49
    • (1998) EMBO J. , vol.17 , pp. 37-49
    • Bossy-Wetzel, E.1
  • 56
    • 3242842321 scopus 로고    scopus 로고
    • Analysis of mitochondrial morphology and function with novel fixable fluorescent stains
    • Poot, M. et al. (1996) Analysis of mitochondrial morphology and function with novel fixable fluorescent stains. j. Histochem. Cytochem. 44, 1363-1372
    • (1996) J. Histochem. Cytochem. , vol.44 , pp. 1363-1372
    • Poot, M.1
  • 57
    • 0026580059 scopus 로고
    • Influx and efflux kinetics of cationic dye binding to respiring mitochondria
    • Bunting, J.R. (1992) Influx and efflux kinetics of cationic dye binding to respiring mitochondria. Biophys. Chem. 42, 163-175
    • (1992) Biophys. Chem. , vol.42 , pp. 163-175
    • Bunting, J.R.1
  • 58
    • 0022492812 scopus 로고
    • Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: Spectral and metabolic properties
    • Emaus, R.K. et al. (1986) Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties. Biochim. Biophys. Acta 850, 436-448
    • (1986) Biochim. Biophys. Acta , vol.850 , pp. 436-448
    • Emaus, R.K.1
  • 59
    • 0019480519 scopus 로고
    • Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy
    • Johnson, L.V. et al. (1981) Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy. J. Cell Biol. 88, 526-535
    • (1981) J. Cell Biol. , vol.88 , pp. 526-535
    • Johnson, L.V.1
  • 60
    • 0033081618 scopus 로고    scopus 로고
    • L regulates apoptosis by heterodimerization-dependent and -independent mechanisms
    • L regulates apoptosis by heterodimerization-dependent and -independent mechanisms. EMBO J. 18, 632-643
    • (1999) EMBO J. , vol.18 , pp. 632-643
    • Minn, A.J.1
  • 61
    • 0028838282 scopus 로고
    • Excitotoxic degeneration is initiated at non-random sites in cultured rat cerebellar neurons
    • Bindokas, V.P. and Miller, R.J. (1995) Excitotoxic degeneration is initiated at non-random sites in cultured rat cerebellar neurons. J. Neurosci. 15, 6999-7011
    • (1995) J. Neurosci. , vol.15 , pp. 6999-7011
    • Bindokas, V.P.1    Miller, R.J.2
  • 62
    • 0026767130 scopus 로고
    • i in type I cells isolated from the rabbit carotid body
    • i in type I cells isolated from the rabbit carotid body. J. Physiol. 450, 33-61
    • (1992) J. Physiol. , vol.450 , pp. 33-61
    • Duchen, M.R.1    Biscoe, T.J.2
  • 63
    • 0026555280 scopus 로고
    • 2+-dependent changes in the mitochondrial energetics in single dissociated mouse sensory neurons
    • 2+-dependent changes in the mitochondrial energetics in single dissociated mouse sensory neurons. Biochem. J. 283, 41-50
    • (1992) Biochem. J. , vol.283 , pp. 41-50
    • Duchen, M.R.1
  • 64
    • 9044243405 scopus 로고    scopus 로고
    • Protective effect of transforming growth factor-beta 1 on beta- Amyloid neurotoxicity in rat hippocampal neurons
    • Prehn, J.H.M. et al. (1996) Protective effect of transforming growth factor-beta 1 on beta- amyloid neurotoxicity in rat hippocampal neurons. Mol.Pharmacol. 49, 319-328
    • (1996) Mol.Pharmacol. , vol.49 , pp. 319-328
    • Prehn, J.H.M.1
  • 65
    • 0345120940 scopus 로고    scopus 로고
    • Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives
    • Scaduto-RC, J. and Grotyohann, L.W. (1999) Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives. Biophys. J. 76, 469-477
    • (1999) Biophys. J. , vol.76 , pp. 469-477
    • Scaduto-Rc, J.1    Grotyohann, L.W.2
  • 66
    • 0024834522 scopus 로고
    • Simultaneous imaging of cell and mitochondrial membrane potentials
    • Farkas, D.L. et al. (1989) Simultaneous imaging of cell and mitochondrial membrane potentials. Biophys. J. 56, 1053-1069
    • (1989) Biophys. J. , vol.56 , pp. 1053-1069
    • Farkas, D.L.1
  • 67
    • 0027146417 scopus 로고
    • Imaging in five dimensions: Time-dependent membrane potentials in individual mitochondria
    • Loew, L.M. et al. (1993) Imaging in five dimensions: time-dependent membrane potentials in individual mitochondria [see comments]. Biophys. J. 65, 2396-2407
    • (1993) Biophys. J. , vol.65 , pp. 2396-2407
    • Loew, L.M.1
  • 68
    • 0033605376 scopus 로고    scopus 로고
    • Mitochondrial depolarization accompanies cytochrome c release during apoptosis in PC6 cells
    • Heiskanen, K.M. et al. (1999) Mitochondrial depolarization accompanies cytochrome c release during apoptosis in PC6 cells. J. Biol. Chem. 274, 5654-5658
    • (1999) J. Biol. Chem. , vol.274 , pp. 5654-5658
    • Heiskanen, K.M.1
  • 69
    • 0023928504 scopus 로고
    • Membrane potential can be determined in individual cells from the nernstian distribution of cationic dyes
    • Ehrenberg, B. et al. (1988) Membrane potential can be determined in individual cells from the nernstian distribution of cationic dyes. Biophys. J. 53, 785-794
    • (1988) Biophys. J. , vol.53 , pp. 785-794
    • Ehrenberg, B.1
  • 71
    • 0028670473 scopus 로고
    • 2+ transients evoke concurrent mitochondrial depolarizations
    • 2+ transients evoke concurrent mitochondrial depolarizations. Proc. Natl. Acad. Sci. U.S.A. 91, 12579-12583
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 12579-12583
    • Loew, L.M.1
  • 72
    • 0032490114 scopus 로고    scopus 로고
    • Inhibitors of NADH-ubiquinone reductase: An overview
    • Degli Esposti, M. (1998) Inhibitors of NADH-ubiquinone reductase: an overview. Biochim. Biophys. Acta 1364, 222-235
    • (1998) Biochim. Biophys. Acta , vol.1364 , pp. 222-235
    • Degli Esposti, M.1
  • 73
    • 0032538051 scopus 로고    scopus 로고
    • Quantitative assay by flow cytometry of the mitochondrial membrane potential in intact cells
    • Rottenberg, H. and Wu, S.L. (1998) Quantitative assay by flow cytometry of the mitochondrial membrane potential in intact cells. Biochim. Biophys. Acta 1404, 393-404
    • (1998) Biochim. Biophys. Acta , vol.1404 , pp. 393-404
    • Rottenberg, H.1    Wu, S.L.2
  • 74
    • 0031558793 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in lymphocytes from old mice: Enhanced activation of the permeability transition
    • Rottenberg, H. and Wu, S. (1997) Mitochondrial dysfunction in lymphocytes from old mice: enhanced activation of the permeability transition. Biochem. Biophys. Res. Commun. 240, 68-74
    • (1997) Biochem. Biophys. Res. Commun. , vol.240 , pp. 68-74
    • Rottenberg, H.1    Wu, S.2
  • 75
    • 0032528118 scopus 로고    scopus 로고
    • Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis
    • Gross, A. et al. (1998) Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis. EMBO J. 17, 3878-3885
    • (1998) EMBO J. , vol.17 , pp. 3878-3885
    • Gross, A.1
  • 76
    • 0032571294 scopus 로고    scopus 로고
    • The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition
    • Pastorino, J.G. et al. (1998) The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition. J. Biol. Chem. 273, 7770-7775
    • (1998) J. Biol. Chem. , vol.273 , pp. 7770-7775
    • Pastorino, J.G.1
  • 77
    • 0025830873 scopus 로고
    • J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential
    • Reers, M. et al. (1991) J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential. Biochemistry 30, 4480-4486
    • (1991) Biochemistry , vol.30 , pp. 4480-4486
    • Reers, M.1
  • 78
    • 0028881848 scopus 로고
    • Mitochondrial membrane potential monitored by JC-1 dye
    • Reers, M. et al. (1995) Mitochondrial membrane potential monitored by JC-1 dye. Methods Enzymol. 260, 406-417
    • (1995) Methods Enzymol. , vol.260 , pp. 406-417
    • Reers, M.1
  • 79
    • 0029065448 scopus 로고
    • Mitochondrial membrane potential in single living adult rat cardiac myocytes exposed to anoxia or metabolic inhibition
    • Di Lisa, F. et al. (1995) Mitochondrial membrane potential in single living adult rat cardiac myocytes exposed to anoxia or metabolic inhibition. J. Physiol. 486, 1-13
    • (1995) J. Physiol. , vol.486 , pp. 1-13
    • Di Lisa, F.1
  • 80
    • 0027374638 scopus 로고
    • A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazol- carbocyanin iodide (JC-1)
    • Cossarizza, A. et al. (1993) A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazol- carbocyanin iodide (JC-1). Biochem. Biophys. Res. Commun. 197, 40-45
    • (1993) Biochem. Biophys. Res. Commun. , vol.197 , pp. 40-45
    • Cossarizza, A.1
  • 81
    • 0030057708 scopus 로고    scopus 로고
    • Functional heterogeneity of an isolated mitochondrial population revealed by cytofluorometric analysis at the single organelle level
    • Cossarizza, A. et al. (1996) Functional heterogeneity of an isolated mitochondrial population revealed by cytofluorometric analysis at the single organelle level. Exp. Cell Res. 222, 84-94
    • (1996) Exp. Cell Res. , vol.222 , pp. 84-94
    • Cossarizza, A.1
  • 82
    • 0030612749 scopus 로고    scopus 로고
    • 6(3) or rhodamine 123, is a reliable fluorescent probe to assess DeltaPsi changes in intact cells: Implications for studies on mitochondrial functionality during apoptosis
    • 6(3) or rhodamine 123, is a reliable fluorescent probe to assess DeltaPsi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis. FEBS Lett. 411, 77-82
    • (1997) FEBS Lett. , vol.411 , pp. 77-82
    • Salvioli, S.1
  • 84
    • 0031689215 scopus 로고    scopus 로고
    • Intracellular fluorescent probe concentrations by confocal microscopy
    • Fink, C. et al. (1998) Intracellular fluorescent probe concentrations by confocal microscopy. Biophys. J. 75, 1648-1658
    • (1998) Biophys. J. , vol.75 , pp. 1648-1658
    • Fink, C.1
  • 85
    • 0029617756 scopus 로고
    • Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo
    • Castedo, M. et al. (1995) Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo. Eur. J. Immunol. 25, 3277-3284
    • (1995) Eur. J. Immunol. , vol.25 , pp. 3277-3284
    • Castedo, M.1
  • 86
    • 0028903933 scopus 로고
    • Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo
    • Zamzami, N. et al. (1995) Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J. Exp. Med. 181, 1661-1672
    • (1995) J. Exp. Med. , vol.181 , pp. 1661-1672
    • Zamzami, N.1
  • 87
    • 0032924009 scopus 로고    scopus 로고
    • Generation of hydrogen peroxide precedes loss of mitochondrial membrane potential during DNA alkylation-induced apoptosis
    • Tada-Oikawa, S. et al. (1999) Generation of hydrogen peroxide precedes loss of mitochondrial membrane potential during DNA alkylation-induced apoptosis. FEBS Lett. 442, 65-69
    • (1999) FEBS Lett. , vol.442 , pp. 65-69
    • Tada-Oikawa, S.1
  • 88
    • 0031589693 scopus 로고    scopus 로고
    • Modulation of neuronal mitochondrial membrane potential by the NMDA receptor: Role of arachidonic acid
    • Camins, A. et al. (1997) Modulation of neuronal mitochondrial membrane potential by the NMDA receptor: role of arachidonic acid. Brain Res. 777, 69-74
    • (1997) Brain Res. , vol.777 , pp. 69-74
    • Camins, A.1
  • 89
    • 0032526921 scopus 로고    scopus 로고
    • Flow cytometric study of mitochondrial dysfunction after AMPA receptor activation
    • Camins, A. et al. (1998) Flow cytometric study of mitochondrial dysfunction after AMPA receptor activation. J. Neurosci. Res. 52, 684-690
    • (1998) J. Neurosci. Res. , vol.52 , pp. 684-690
    • Camins, A.1
  • 90
    • 0017880705 scopus 로고
    • Changes in membrane potential during calcium ion influx and efflux across the mitochondrial membrane
    • Åkerman, K.E.O. (1978) Changes in membrane potential during calcium ion influx and efflux across the mitochondrial membrane. Biochim. Biophys. Acta 502, 359-366
    • (1978) Biochim. Biophys. Acta , vol.502 , pp. 359-366
    • Åkerman, K.E.O.1
  • 91
    • 0007574262 scopus 로고
    • Localization of mitochondria in living cells with rhodamine 123
    • Johnson, L.V. et al. (1980) Localization of mitochondria in living cells with rhodamine 123. Proc. Natl. Acad. Sci. U. S. A. 77, 990-994
    • (1980) Proc. Natl. Acad. Sci. U. S. A. , vol.77 , pp. 990-994
    • Johnson, L.V.1
  • 92
    • 0026580059 scopus 로고
    • Influx and efflux kinetics of cationic dye binding to respiring mitochondria
    • Bunting, J.R. (1992) Influx and efflux kinetics of cationic dye binding to respiring mitochondria. Biophys. Chem. 42, 163-175
    • (1992) Biophys. Chem. , vol.42 , pp. 163-175
    • Bunting, J.R.1
  • 93
    • 17344371804 scopus 로고    scopus 로고
    • Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: Suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction
    • Keller, J.N. et al. (1998) Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction. J. Neurosci. 18, 687-697
    • (1998) J. Neurosci. , vol.18 , pp. 687-697
    • Keller, J.N.1
  • 94
    • 0030574021 scopus 로고    scopus 로고
    • Calcineurin and mitochondrial function in glutamate-induced neuronal cell death
    • Ankarcrona, M. et al. (1996) Calcineurin and mitochondrial function in glutamate-induced neuronal cell death. FEBS Lett. 394, 321-324
    • (1996) FEBS Lett. , vol.394 , pp. 321-324
    • Ankarcrona, M.1
  • 95
    • 0030729437 scopus 로고    scopus 로고
    • Trifluoperazine and dibucaine-induced inhibition of glutamate-induced mitochondrial depolarization in rat cultured forebrain neurones
    • Hoyt, K.R. et al. (1997) Trifluoperazine and dibucaine-induced inhibition of glutamate-induced mitochondrial depolarization in rat cultured forebrain neurones. Br. J. Pharmacol. 122, 803-808
    • (1997) Br. J. Pharmacol. , vol.122 , pp. 803-808
    • Hoyt, K.R.1
  • 96
    • 0032523737 scopus 로고    scopus 로고
    • 2+ changes in rat forebrain neurones
    • in press
    • 2+ changes in rat forebrain neurones. J. Physiol. (in press)
    • J. Physiol.
    • Hoyt, K.R.1
  • 97
    • 0344603640 scopus 로고    scopus 로고
    • Glutathione depletion and neuronal cell death: The role of reactive oxygen intermediates and mitochondrial function
    • Wüllner, U. et al. (1999) Glutathione depletion and neuronal cell death: the role of reactive oxygen intermediates and mitochondrial function. Brain Res. 826, 53-62
    • (1999) Brain Res. , vol.826 , pp. 53-62
    • Wüllner, U.1
  • 98
    • 0018864653 scopus 로고
    • Energy transduction in intact synaptosomes: Influence of plasma-membrane depolarization on the respiration and membrane potential of internal mitochondria determined in situ
    • Scott, I.D. and Nicholls, D.G. (1980) Energy transduction in intact synaptosomes: influence of plasma-membrane depolarization on the respiration and membrane potential of internal mitochondria determined in situ. Biochem. J. 186, 21-23
    • (1980) Biochem. J. , vol.186 , pp. 21-23
    • Scott, I.D.1    Nicholls, D.G.2
  • 99
    • 0029834431 scopus 로고    scopus 로고
    • Rapid uncoupling of oxidative phosphorylation accompanies glutamate toxicity in rat cerebellar granule cells
    • Atlante, A. et al. (1996) Rapid uncoupling of oxidative phosphorylation accompanies glutamate toxicity in rat cerebellar granule cells. NeuroReport 7, 2519-2523
    • (1996) NeuroReport , vol.7 , pp. 2519-2523
    • Atlante, A.1
  • 100
    • 0029969392 scopus 로고    scopus 로고
    • Oxidative modification of a carboxylterminal vicinal methionine in calmodulin by hydrogen peroxide inhibits calmodulin-dependent activation of the plasma membrane Ca-ATPase
    • Yao, Y. et al. (1996) Oxidative modification of a carboxylterminal vicinal methionine in calmodulin by hydrogen peroxide inhibits calmodulin-dependent activation of the plasma membrane Ca-ATPase. Biochemistry 35, 2767-2787
    • (1996) Biochemistry , vol.35 , pp. 2767-2787
    • Yao, Y.1
  • 101
    • 0031885987 scopus 로고    scopus 로고
    • Loss of conformational stability in calmodulin upon methionine oxidation
    • Gao, J. et al. (1998) Loss of conformational stability in calmodulin upon methionine oxidation. Biophys. J. 74, 1115-1134
    • (1998) Biophys. J. , vol.74 , pp. 1115-1134
    • Gao, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.