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Volumn 2014, Issue , 2014, Pages

Genetics of type 2 diabetes: Insights into the pathogenesis and its clinical application

Author keywords

[No Author keywords available]

Indexed keywords

ASIAN; DISEASE PREDISPOSITION; ETHNICITY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETICS; HUMAN; LINKAGE ANALYSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PHARMACOGENOMICS; REVIEW; GENETIC PREDISPOSITION; PHARMACOGENETICS; RESEARCH; TRENDS;

EID: 84900022532     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/926713     Document Type: Review
Times cited : (78)

References (183)
  • 1
    • 73749083481 scopus 로고    scopus 로고
    • Global estimates of the prevalence of diabetes for 2010 and 2030
    • 2-s2.0-73749083481 10.1016/j.diabres.2009.10.007
    • Shaw J. E., Sicree R. A., Zimmet P. Z., Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Research and Clinical Practice 2010 87 1 4 14 2-s2.0-73749083481 10.1016/j.diabres.2009.10.007
    • (2010) Diabetes Research and Clinical Practice , vol.87 , Issue.1 , pp. 4-14
    • Shaw, J.E.1    Sicree, R.A.2    Zimmet, P.Z.3
  • 4
    • 65349192772 scopus 로고    scopus 로고
    • Joint effects of common genetic variants on the risk for type 2 diabetes in US men and women of European ancestry
    • 2-s2.0-65349192772
    • Cornelis M. C., Qi L., Zhang C., Kraft P., Manson J., Cai T., Hunter D. J., Hu F. B., Joint effects of common genetic variants on the risk for type 2 diabetes in US men and women of European ancestry. Annals of Internal Medicine 2009 150 8 541 550 2-s2.0-65349192772
    • (2009) Annals of Internal Medicine , vol.150 , Issue.8 , pp. 541-550
    • Cornelis, M.C.1    Qi, L.2    Zhang, C.3    Kraft, P.4    Manson, J.5    Cai, T.6    Hunter, D.J.7    Hu, F.B.8
  • 6
    • 80051766486 scopus 로고    scopus 로고
    • Pharmacogenomics of oral antidiabetic medications: Current data and pharmacoepigenomic perspective
    • 2-s2.0-80051766486 10.2217/pgs.11.65
    • Manolopoulos V. G., Ragia G., Tavridou A., Pharmacogenomics of oral antidiabetic medications: current data and pharmacoepigenomic perspective. Pharmacogenomics 2011 12 8 1161 1191 2-s2.0-80051766486 10.2217/pgs.11.65
    • (2011) Pharmacogenomics , vol.12 , Issue.8 , pp. 1161-1191
    • Manolopoulos, V.G.1    Ragia, G.2    Tavridou, A.3
  • 7
    • 82255186505 scopus 로고    scopus 로고
    • Pharmacogenetics in type 2 diabetes: Potential implications for clinical practice
    • 2-s2.0-82255186505 10.1186/gm292
    • Huang C., Florez J. C., Pharmacogenetics in type 2 diabetes: potential implications for clinical practice. Genome Medicine 2011 3 11, article 76 2-s2.0-82255186505 10.1186/gm292
    • (2011) Genome Medicine , vol.3 , Issue.11
    • Huang, C.1    Florez, J.C.2
  • 12
    • 34547510624 scopus 로고    scopus 로고
    • Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes
    • 10.1038/ng2062
    • Gudmundsson J., Sulem P., Steinthorsdottir V., Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nature Genetics 2007 39 8 977 983 10.1038/ng2062
    • (2007) Nature Genetics , vol.39 , Issue.8 , pp. 977-983
    • Gudmundsson, J.1    Sulem, P.2    Steinthorsdottir, V.3
  • 13
    • 34249895023 scopus 로고    scopus 로고
    • Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
    • Zeggini E., Weedon M. N., Lindgren C. M., Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 2007 316 5829 1336 1341
    • (2007) Science , vol.316 , Issue.5829 , pp. 1336-1341
    • Zeggini, E.1    Weedon, M.N.2    Lindgren, C.M.3
  • 19
    • 42349106044 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
    • 2-s2.0-42349106044 10.1038/ng.120
    • Zeggini E., Scott L. J., Saxena R., Voight B. F., Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nature Genetics 2008 40 5 638 645 2-s2.0-42349106044 10.1038/ng.120
    • (2008) Nature Genetics , vol.40 , Issue.5 , pp. 638-645
    • Zeggini, E.1    Scott, L.J.2    Saxena, R.3    Voight, B.F.4
  • 22
    • 75749086085 scopus 로고    scopus 로고
    • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
    • Dupuis J., Langenberg C., Prokopenko I., New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nature Genetics 2010 42 2 105 116
    • (2010) Nature Genetics , vol.42 , Issue.2 , pp. 105-116
    • Dupuis, J.1    Langenberg, C.2    Prokopenko, I.3
  • 24
    • 77954143522 scopus 로고    scopus 로고
    • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
    • 10.1038/ng.609
    • Voight B. F., Scott L. J., Steinthorsdottir V., Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nature Genetics 2010 42 7 579 589 10.1038/ng.609
    • (2010) Nature Genetics , vol.42 , Issue.7 , pp. 579-589
    • Voight, B.F.1    Scott, L.J.2    Steinthorsdottir, V.3
  • 25
    • 84868337361 scopus 로고    scopus 로고
    • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
    • 10.1038/ng.2383
    • Morris A. P., Voight B. F., Teslovich T. M., Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nature Genetics 2012 44 9 981 990 10.1038/ng.2383
    • (2012) Nature Genetics , vol.44 , Issue.9 , pp. 981-990
    • Morris, A.P.1    Voight, B.F.2    Teslovich, T.M.3
  • 26
    • 67349205597 scopus 로고    scopus 로고
    • Variations in KCNQ1 are associated with type 2 diabetes and beta cell function in a Chinese population
    • 2-s2.0-67349205597 10.1007/s00125-009-1335-6
    • Hu C., Wang C., Zhang R., Ma X., Wang J., Lu J., Qin W., Bao Y., Xiang K., Jia W., Variations in KCNQ1 are associated with type 2 diabetes and beta cell function in a Chinese population. Diabetologia 2009 52 7 1322 1325 2-s2.0-67349205597 10.1007/s00125-009-1335-6
    • (2009) Diabetologia , vol.52 , Issue.7 , pp. 1322-1325
    • Hu, C.1    Wang, C.2    Zhang, R.3    Ma, X.4    Wang, J.5    Lu, J.6    Qin, W.7    Bao, Y.8    Xiang, K.9    Jia, W.10
  • 28
    • 78049438674 scopus 로고    scopus 로고
    • Identification of new genetic risk variants for type 2 diabetes
    • e1001127 10.1371/journal.pgen.1001127
    • Shu X. O., Long J., Cai Q., Identification of new genetic risk variants for type 2 diabetes. PLoS Genetics 2010 6 9 e1001127 10.1371/journal.pgen. 1001127
    • (2010) PLoS Genetics , vol.6 , Issue.9
    • Shu, X.O.1    Long, J.2    Cai, Q.3
  • 30
    • 84655162045 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians
    • Cho Y. S., Chen C. H., Hu C., Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nature Genetics 2012 44 1 67 72
    • (2012) Nature Genetics , vol.44 , Issue.1 , pp. 67-72
    • Cho, Y.S.1    Chen, C.H.2    Hu, C.3
  • 31
    • 84863503465 scopus 로고    scopus 로고
    • A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations
    • 10.1093/hmg/dds113
    • Imamura M., Maeda S., Yamauchi T., A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations. Human Molecular Genetics 2012 21 13 3042 3049 10.1093/hmg/dds113
    • (2012) Human Molecular Genetics , vol.21 , Issue.13 , pp. 3042-3049
    • Imamura, M.1    Maeda, S.2    Yamauchi, T.3
  • 32
    • 84872033833 scopus 로고    scopus 로고
    • A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans
    • 10.2337/db12-0454
    • Li H., Gan W., Lu L., A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans. Diabetes 2013 62 1 291 298 10.2337/db12-0454
    • (2013) Diabetes , vol.62 , Issue.1 , pp. 291-298
    • Li, H.1    Gan, W.2    Lu, L.3
  • 33
    • 84877728324 scopus 로고    scopus 로고
    • Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4
    • Ma R. C., Hu C., Tam C. H., Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4. Diabetologia 2013 56 6 1291 1305
    • (2013) Diabetologia , vol.56 , Issue.6 , pp. 1291-1305
    • Ma, R.C.1    Hu, C.2    Tam, C.H.3
  • 34
    • 84890397941 scopus 로고    scopus 로고
    • Genome-wide association study identifies three novel loci for type 2 diabetes
    • 10.1093/hmg/ddt399
    • Hara K., Fujita H., Johnson T. A., Genome-wide association study identifies three novel loci for type 2 diabetes. Human Molecular Genetics 2014 23 1 239 246 10.1093/hmg/ddt399
    • (2014) Human Molecular Genetics , vol.23 , Issue.1 , pp. 239-246
    • Hara, K.1    Fujita, H.2    Johnson, T.A.3
  • 35
    • 80053385333 scopus 로고    scopus 로고
    • Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci
    • 10.1038/ng.921
    • Kooner J. S., Saleheen D., Sim X., Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nature Genetics 2011 43 10 984 989 10.1038/ng.921
    • (2011) Nature Genetics , vol.43 , Issue.10 , pp. 984-989
    • Kooner, J.S.1    Saleheen, D.2    Sim, X.3
  • 36
    • 84874418247 scopus 로고    scopus 로고
    • Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21
    • 10.2337/db12-0406
    • Tabassum R., Chauhan G., Dwivedi O. P., Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21. Diabetes 2013 62 3 977 986 10.2337/db12-0406
    • (2013) Diabetes , vol.62 , Issue.3 , pp. 977-986
    • Tabassum, R.1    Chauhan, G.2    Dwivedi, O.P.3
  • 37
    • 84876536835 scopus 로고    scopus 로고
    • Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India
    • 10.2337/db12-1077
    • Saxena R., Saleheen D., Been L. F., Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. Diabetes 2013 62 5 1746 1755 10.2337/db12-1077
    • (2013) Diabetes , vol.62 , Issue.5 , pp. 1746-1755
    • Saxena, R.1    Saleheen, D.2    Been, L.F.3
  • 38
    • 0035960122 scopus 로고    scopus 로고
    • Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young
    • 2-s2.0-0035960122 10.1056/NEJMra002168
    • Fajans S. S., Bell G. I., Polonsky K. S., Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young. The New England Journal of Medicine 2001 345 13 971 980 2-s2.0-0035960122 10.1056/NEJMra002168
    • (2001) The New England Journal of Medicine , vol.345 , Issue.13 , pp. 971-980
    • Fajans, S.S.1    Bell, G.I.2    Polonsky, K.S.3
  • 39
    • 17844373857 scopus 로고    scopus 로고
    • Genetics of type 2 diabetes
    • 2-s2.0-17844373857 10.1111/j.1464-5491.2005.01550.x
    • Barroso I., Genetics of type 2 diabetes. Diabetic Medicine 2005 22 5 517 535 2-s2.0-17844373857 10.1111/j.1464-5491.2005.01550.x
    • (2005) Diabetic Medicine , vol.22 , Issue.5 , pp. 517-535
    • Barroso, I.1
  • 40
    • 43549084587 scopus 로고    scopus 로고
    • Monogenic diabetes in the young, pharmacogenetics and relevance to multifactorial forms of type 2 diabetes
    • 2-s2.0-43549084587 10.1210/er.2007-0024
    • Vaxillaire M., Froguel P., Monogenic diabetes in the young, pharmacogenetics and relevance to multifactorial forms of type 2 diabetes. Endocrine Reviews 2008 29 3 254 264 2-s2.0-43549084587 10.1210/er.2007-0024
    • (2008) Endocrine Reviews , vol.29 , Issue.3 , pp. 254-264
    • Vaxillaire, M.1    Froguel, P.2
  • 41
    • 0033772073 scopus 로고    scopus 로고
    • Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
    • 10.1038/79876
    • Horikawa Y., Oda N., Cox N. J., Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nature Genetics 2000 26 2 163 175 10.1038/79876
    • (2000) Nature Genetics , vol.26 , Issue.2 , pp. 163-175
    • Horikawa, Y.1    Oda, N.2    Cox, N.J.3
  • 43
    • 1842422877 scopus 로고    scopus 로고
    • A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor-4 α gene on chromosome 20 q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an Ashkenazi Jewish population
    • 2-s2.0-1842422877 10.2337/diabetes.53.4.1134
    • Love-Gregory L. D., Wasson J., Ma J., Jin C. H., Glaser B., Suarez B. K., Permutt M. A., A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor-4 α gene on chromosome 20 q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an Ashkenazi Jewish population. Diabetes 2004 53 4 1134 1140 2-s2.0-1842422877 10.2337/diabetes.53.4.1134
    • (2004) Diabetes , vol.53 , Issue.4 , pp. 1134-1140
    • Love-Gregory, L.D.1    Wasson, J.2    Ma, J.3    Jin, C.H.4    Glaser, B.5    Suarez, B.K.6    Permutt, M.A.7
  • 45
    • 18644369745 scopus 로고    scopus 로고
    • Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians
    • 2-s2.0-18644369745 10.1093/hmg/11.21.2607
    • Vasseur F., Helbecque N., Dina C., Lobbens S., Delannoy V., Gaget S., Boutin P., Vaxillaire M., Leprêtre F., Dupont S., Hara K., Clément K., Bihain B., Kadowaki T., Froguel P., Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians. Human Molecular Genetics 2002 11 21 2607 2614 2-s2.0-18644369745 10.1093/hmg/11.21.2607
    • (2002) Human Molecular Genetics , vol.11 , Issue.21 , pp. 2607-2614
    • Vasseur, F.1    Helbecque, N.2    Dina, C.3    Lobbens, S.4    Delannoy, V.5    Gaget, S.6    Boutin, P.7    Vaxillaire, M.8    Leprêtre, F.9    Dupont, S.10    Hara, K.11    Clément, K.12    Bihain, B.13    Kadowaki, T.14    Froguel, P.15
  • 46
    • 0031595923 scopus 로고    scopus 로고
    • A Pro12Ala substitution in PPAR γ 2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
    • 2-s2.0-0031595923 10.1038/3099
    • Deeb S. S., Fajas L., Nemoto M., Pihlajamäki J., Mykkänen L., Kuusisto J., Laakso M., Fujimoto W., Auwerx J., A Pro12Ala substitution in PPAR γ 2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nature Genetics 1998 20 3 284 287 2-s2.0-0031595923 10.1038/3099
    • (1998) Nature Genetics , vol.20 , Issue.3 , pp. 284-287
    • Deeb, S.S.1    Fajas, L.2    Nemoto, M.3    Pihlajamäki, J.4    Mykkänen, L.5    Kuusisto, J.6    Laakso, M.7    Fujimoto, W.8    Auwerx, J.9
  • 47
    • 0024599929 scopus 로고
    • Genetically programmed selective islet β -cell loss in diabetic subjects with Wolfram's syndrome
    • 2-s2.0-0024599929
    • Karasik A., O'Hara C., Srikanta S., Swift M., Soeldner J. S., Kahn C. R., Herskowitz R. D., Genetically programmed selective islet β -cell loss in diabetic subjects with Wolfram's syndrome. Diabetes Care 1989 12 2 135 138 2-s2.0-0024599929
    • (1989) Diabetes Care , vol.12 , Issue.2 , pp. 135-138
    • Karasik, A.1    O'Hara, C.2    Srikanta, S.3    Swift, M.4    Soeldner, J.S.5    Kahn, C.R.6    Herskowitz, R.D.7
  • 48
    • 27744523525 scopus 로고    scopus 로고
    • Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis
    • 2-s2.0-27744523525 10.1007/s00125-005-1947-4
    • Riggs A. C., Bernal-Mizrachi E., Ohsugi M., Wasson J., Fatrai S., Welling C., Murray J., Schmidt R. E., Herrera P. L., Permutt M. A., Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis. Diabetologia 2005 48 11 2313 2321 2-s2.0-27744523525 10.1007/s00125-005-1947-4
    • (2005) Diabetologia , vol.48 , Issue.11 , pp. 2313-2321
    • Riggs, A.C.1    Bernal-Mizrachi, E.2    Ohsugi, M.3    Wasson, J.4    Fatrai, S.5    Welling, C.6    Murray, J.7    Schmidt, R.E.8    Herrera, P.L.9    Permutt, M.A.10
  • 50
    • 33750602980 scopus 로고    scopus 로고
    • Association analysis of 6,736 UK subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk
    • 2-s2.0-33750602980 10.2337/db06-0355
    • Groves C. J., Zeggini E., Minton J., Frayling T. M., Weedon M. N., Rayner N. W., Hitman G. A., Walker M., Wiltshire S., Hattersley A. T., McCarthy M. I., Association analysis of 6,736 UK subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk. Diabetes 2006 55 9 2640 2644 2-s2.0-33750602980 10.2337/db06-0355
    • (2006) Diabetes , vol.55 , Issue.9 , pp. 2640-2644
    • Groves, C.J.1    Zeggini, E.2    Minton, J.3    Frayling, T.M.4    Weedon, M.N.5    Rayner, N.W.6    Hitman, G.A.7    Walker, M.8    Wiltshire, S.9    Hattersley, A.T.10    McCarthy, M.I.11
  • 51
    • 33750594321 scopus 로고    scopus 로고
    • Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes in large cohorts of US women and men
    • 2-s2.0-33750594321 10.2337/db06-0643
    • Zhang C., Qi L., Hunter D. J., Meigs J. B., Manson J. E., Van Dam R. M., Hu F. B., Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes in large cohorts of US women and men. Diabetes 2006 55 9 2645 2648 2-s2.0-33750594321 10.2337/db06-0643
    • (2006) Diabetes , vol.55 , Issue.9 , pp. 2645-2648
    • Zhang, C.1    Qi, L.2    Hunter, D.J.3    Meigs, J.B.4    Manson, J.E.5    Van Dam, R.M.6    Hu, F.B.7
  • 53
    • 33750584981 scopus 로고    scopus 로고
    • Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: Replication and evidence for a role in both insulin secretion and insulin resistance
    • 2-s2.0-33750584981 10.2337/db06-0338
    • Damcott C. M., Pollin T. I., Reinhart L. J., Ott S. H., Shen H., Silver K. D., Mitchell B. D., Shuldiner A. R., Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: replication and evidence for a role in both insulin secretion and insulin resistance. Diabetes 2006 55 9 2654 2659 2-s2.0-33750584981 10.2337/db06-0338
    • (2006) Diabetes , vol.55 , Issue.9 , pp. 2654-2659
    • Damcott, C.M.1    Pollin, T.I.2    Reinhart, L.J.3    Ott, S.H.4    Shen, H.5    Silver, K.D.6    Mitchell, B.D.7    Shuldiner, A.R.8
  • 55
    • 33750889376 scopus 로고    scopus 로고
    • Transcription factor TCF7L2 genetic study in the French population: Expression in human β -cells and adipose tissue and strong association with type 2 diabetes
    • 2-s2.0-33750889376 10.2337/db06-0474
    • Cauchi S., Meyre D., Dina C., Choquet H., Samson C., Gallina S., Balkau B., Charpentier G., Pattou F., Stetsyuk V., Scharfmann R., Staels B., Frühbeck G., Froguel P., Transcription factor TCF7L2 genetic study in the French population: expression in human β -cells and adipose tissue and strong association with type 2 diabetes. Diabetes 2006 55 10 2903 2908 2-s2.0-33750889376 10.2337/db06-0474
    • (2006) Diabetes , vol.55 , Issue.10 , pp. 2903-2908
    • Cauchi, S.1    Meyre, D.2    Dina, C.3    Choquet, H.4    Samson, C.5    Gallina, S.6    Balkau, B.7    Charpentier, G.8    Pattou, F.9    Stetsyuk, V.10    Scharfmann, R.11    Staels, B.12    Frühbeck, G.13    Froguel, P.14
  • 56
    • 34147119644 scopus 로고    scopus 로고
    • Replication study for the association of TCF7L2 with susceptibility to type 2 diabetes in a Japanese population
    • 2-s2.0-34147119644 10.1007/s00125-007-0618-z
    • Hayashi T., Iwamoto Y., Kaku K., Hirose H., Maeda S., Replication study for the association of TCF7L2 with susceptibility to type 2 diabetes in a Japanese population. Diabetologia 2007 50 5 980 984 2-s2.0-34147119644 10.1007/s00125-007-0618-z
    • (2007) Diabetologia , vol.50 , Issue.5 , pp. 980-984
    • Hayashi, T.1    Iwamoto, Y.2    Kaku, K.3    Hirose, H.4    Maeda, S.5
  • 57
    • 33847618213 scopus 로고    scopus 로고
    • A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population
    • 2-s2.0-33847618213 10.1007/s00125-006-0588-6
    • Horikoshi M., Hara K., Ito C., Nagai R., Froguel P., Kadowaki T., A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population. Diabetologia 2007 50 4 747 751 2-s2.0-33847618213 10.1007/s00125-006-0588-6
    • (2007) Diabetologia , vol.50 , Issue.4 , pp. 747-751
    • Horikoshi, M.1    Hara, K.2    Ito, C.3    Nagai, R.4    Froguel, P.5    Kadowaki, T.6
  • 58
    • 13244291649 scopus 로고    scopus 로고
    • Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex
    • 2-s2.0-13244291649 10.1101/gad.1279405
    • Foley A. C., Mercola M., Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex. Genes & Development 2005 19 3 387 396 2-s2.0-13244291649 10.1101/gad.1279405
    • (2005) Genes & Development , vol.19 , Issue.3 , pp. 387-396
    • Foley, A.C.1    Mercola, M.2
  • 60
    • 50049119989 scopus 로고    scopus 로고
    • Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123 / CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 Loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged danes
    • 2-s2.0-50049119989 10.2337/db08-0436
    • Grarup N., Andersen G., Krarup N. T., Albrechtsen A., Schmitz O., Joørgensen T., Borch-Johnsen K., Hansen T., Pedersen O., Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123 / CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 Loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged danes. Diabetes 2008 57 9 2534 2540 2-s2.0-50049119989 10.2337/db08-0436
    • (2008) Diabetes , vol.57 , Issue.9 , pp. 2534-2540
    • Grarup, N.1    Andersen, G.2    Krarup, N.T.3    Albrechtsen, A.4    Schmitz, O.5    Joørgensen, T.6    Borch-Johnsen, K.7    Hansen, T.8    Pedersen, O.9
  • 61
    • 58149156287 scopus 로고    scopus 로고
    • Variants in MTNR1B influence fasting glucose levels
    • 10.1038/ng.290
    • Prokopenko I., Langenberg C., Florez J. C., Variants in MTNR1B influence fasting glucose levels. Nature Genetics 2009 41 1 77 81 10.1038/ng.290
    • (2009) Nature Genetics , vol.41 , Issue.1 , pp. 77-81
    • Prokopenko, I.1    Langenberg, C.2    Florez, J.C.3
  • 62
    • 84884383343 scopus 로고    scopus 로고
    • 3 family with a novel HNF1A germline mutation
    • 10.1016/j.jhep.2013.05.024
    • 3 family with a novel HNF1A germline mutation. Journal of Hepatology 2013 59 4 904 907 10.1016/j.jhep.2013.05.024
    • (2013) Journal of Hepatology , vol.59 , Issue.4 , pp. 904-907
    • Willson, J.S.1    Godwin, T.D.2    Wiggins, G.A.3
  • 63
    • 63249116231 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 1- α mutation in normal glucose-tolerant subjects and early-onset type 2 diabetic patients
    • 2-s2.0-63249116231 10.3904/kjim.2008.23.4.165
    • Lim D. M., Huh N., Park K. Y., Hepatocyte nuclear factor 1- α mutation in normal glucose-tolerant subjects and early-onset type 2 diabetic patients. Korean Journal of Internal Medicine 2008 23 4 165 169 2-s2.0-63249116231 10.3904/kjim.2008.23.4.165
    • (2008) Korean Journal of Internal Medicine , vol.23 , Issue.4 , pp. 165-169
    • Lim, D.M.1    Huh, N.2    Park, K.Y.3
  • 64
    • 0033027001 scopus 로고    scopus 로고
    • The hepatic nuclear factor-1 α G319S variant is associated with early-onset type 2 diabetes in Canadian Oji-Cree
    • 2-s2.0-0033027001
    • Hegele R. A., Cao H., Harris S. B., Hanley A. J. G., Zinman B., The hepatic nuclear factor-1 α G319S variant is associated with early-onset type 2 diabetes in Canadian Oji-Cree. The Journal of Clinical Endocrinology & Metabolism 1999 84 3 1077 1082 2-s2.0-0033027001
    • (1999) The Journal of Clinical Endocrinology & Metabolism , vol.84 , Issue.3 , pp. 1077-1082
    • Hegele, R.A.1    Cao, H.2    Harris, S.B.3    Hanley, A.J.G.4    Zinman, B.5
  • 65
    • 0042530516 scopus 로고    scopus 로고
    • Dual specificity mitogen-activated protein (MAP) kinase phosphatase-4 plays a potential role in insulin resistance
    • 2-s2.0-0042530516 10.1074/jbc.M302010200
    • Xu H., Dembski M., Yang Q., Yang D., Moriarty A., Tayber O., Chen H., Kapeller R., Tartaglia L. A., Dual specificity mitogen-activated protein (MAP) kinase phosphatase-4 plays a potential role in insulin resistance. The Journal of Biological Chemistry 2003 278 32 30187 30192 2-s2.0-0042530516 10.1074/jbc.M302010200
    • (2003) The Journal of Biological Chemistry , vol.278 , Issue.32 , pp. 30187-30192
    • Xu, H.1    Dembski, M.2    Yang, Q.3    Yang, D.4    Moriarty, A.5    Tayber, O.6    Chen, H.7    Kapeller, R.8    Tartaglia, L.A.9
  • 66
    • 3042836359 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase (MAPK) phosphatase-1 and -4 attenuate p38 MAPK during dexamethasone-induced insulin resistance in 3T3-L1 adipocytes
    • 2-s2.0-3042836359 10.1210/me.2003-0213
    • Bazuine M., Carlotti F., Tafrechi R. S., Hoeben R. C., Maassen J. A., Mitogen-activated protein kinase (MAPK) phosphatase-1 and -4 attenuate p38 MAPK during dexamethasone-induced insulin resistance in 3T3-L1 adipocytes. Molecular Endocrinology 2004 18 7 1697 1707 2-s2.0-3042836359 10.1210/me.2003-0213
    • (2004) Molecular Endocrinology , vol.18 , Issue.7 , pp. 1697-1707
    • Bazuine, M.1    Carlotti, F.2    Tafrechi, R.S.3    Hoeben, R.C.4    Maassen, J.A.5
  • 67
    • 42149155999 scopus 로고    scopus 로고
    • Overexpression of the dual-specificity phosphatase MKP-4/DUSP-9 protects against stress-induced insulin resistance
    • 2-s2.0-42149155999 10.1073/pnas.0712275105
    • Emanuelli B., Eberlé D., Suzuki R., Kahn C. R., Overexpression of the dual-specificity phosphatase MKP-4/DUSP-9 protects against stress-induced insulin resistance. Proceedings of the National Academy of Sciences of the United States of America 2008 105 9 3545 3550 2-s2.0-42149155999 10.1073/pnas.0712275105
    • (2008) Proceedings of the National Academy of Sciences of the United States of America , vol.105 , Issue.9 , pp. 3545-3550
    • Emanuelli, B.1    Eberlé, D.2    Suzuki, R.3    Kahn, C.R.4
  • 68
    • 84876219189 scopus 로고    scopus 로고
    • Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with decreased β -cell function whereas risk alleles near ANKRD55 and GRB14 associate with decreased insulin sensitivity in the Danish Inter99 cohort
    • 10.1210/jc.2012-4169
    • Harder M. N., Ribel-Madsen R., Justesen J. M., Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with decreased β -cell function whereas risk alleles near ANKRD55 and GRB14 associate with decreased insulin sensitivity in the Danish Inter99 cohort. The Journal of Clinical Endocrinology & Metabolism 2013 98 4 E801 E806 10.1210/jc.2012-4169
    • (2013) The Journal of Clinical Endocrinology & Metabolism , vol.98 , Issue.4
    • Harder, M.N.1    Ribel-Madsen, R.2    Justesen, J.M.3
  • 69
    • 84870538495 scopus 로고    scopus 로고
    • Diabetes prevalence and determinants in adults in China mainland from 2000 to 2010: A systematic review
    • 10.1016/j.diabres.2012.05.010
    • Li H., Oldenburg B., Chamberlain C., Diabetes prevalence and determinants in adults in China mainland from 2000 to 2010: a systematic review. Diabetes Research and Clinical Practice 2012 98 2 226 235 10.1016/j.diabres.2012.05.010
    • (2012) Diabetes Research and Clinical Practice , vol.98 , Issue.2 , pp. 226-235
    • Li, H.1    Oldenburg, B.2    Chamberlain, C.3
  • 70
    • 50449085998 scopus 로고    scopus 로고
    • Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
    • 10.1038/ng.207
    • Yasuda K., Miyake K., Horikawa Y., Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nature Genetics 2008 40 9 1092 1097 10.1038/ng.207
    • (2008) Nature Genetics , vol.40 , Issue.9 , pp. 1092-1097
    • Yasuda, K.1    Miyake, K.2    Horikawa, Y.3
  • 72
    • 57349191471 scopus 로고    scopus 로고
    • Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population
    • 2-s2.0-57349191471 10.1007/s10038-008-0341-8
    • Lee Y.-H., Kang E. S., Kim S. H., Han S. J., Kim C. H., Kim H. J., Ahn C. W., Cha B. S., Nam M., Nam C. M., Lee H. C., Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population. Journal of Human Genetics 2008 53 11-12 991 998 2-s2.0-57349191471 10.1007/s10038-008-0341-8
    • (2008) Journal of Human Genetics , vol.53 , Issue.11-12 , pp. 991-998
    • Lee, Y.-H.1    Kang, E.S.2    Kim, S.H.3    Han, S.J.4    Kim, C.H.5    Kim, H.J.6    Ahn, C.W.7    Cha, B.S.8    Nam, M.9    Nam, C.M.10    Lee, H.C.11
  • 73
    • 66649101376 scopus 로고    scopus 로고
    • Genetic variation in KCNQ1 associates with fasting glucose and β -cell function: A study of 3,734 subjects comprising three ethnicities living in Singapore
    • 2-s2.0-66649101376 10.2337/db08-1138
    • Tan J. T., Nurbaya S., Gardner D., Ye S., Tai E. S., Ng D. P. K., Genetic variation in KCNQ1 associates with fasting glucose and β -cell function: a study of 3,734 subjects comprising three ethnicities living in Singapore. Diabetes 2009 58 6 1445 1449 2-s2.0-66649101376 10.2337/db08-1138
    • (2009) Diabetes , vol.58 , Issue.6 , pp. 1445-1449
    • Tan, J.T.1    Nurbaya, S.2    Gardner, D.3    Ye, S.4    Tai, E.S.5    Ng, D.P.K.6
  • 75
    • 84863046601 scopus 로고    scopus 로고
    • Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort
    • 10.1111/j.1365-2265.2011.04175.x
    • Chang Y. C., Chiu Y. F., Liu P. H., Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort. Clinical Endocrinology 2012 76 3 365 372 10.1111/j.1365-2265.2011.04175.x
    • (2012) Clinical Endocrinology , vol.76 , Issue.3 , pp. 365-372
    • Chang, Y.C.1    Chiu, Y.F.2    Liu, P.H.3
  • 76
    • 0033539510 scopus 로고    scopus 로고
    • Serine racemase: A glial enzyme synthesizing D-serine to regulate glutamate- N -methyl-D-aspartate neurotransmission
    • 2-s2.0-0033539510 10.1073/pnas.96.23.13409
    • Wolosker H., Blackshaw S., Snyder S. H., Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate- N -methyl-D-aspartate neurotransmission. Proceedings of the National Academy of Sciences of the United States of America 1999 96 23 13409 13414 2-s2.0-0033539510 10.1073/pnas.96.23. 13409
    • (1999) Proceedings of the National Academy of Sciences of the United States of America , vol.96 , Issue.23 , pp. 13409-13414
    • Wolosker, H.1    Blackshaw, S.2    Snyder, S.H.3
  • 78
    • 78649461131 scopus 로고    scopus 로고
    • 1C levels via glycemic and nonglycemic pathways
    • 10.2337/db10-0502
    • 1C levels via glycemic and nonglycemic pathways. Diabetes 2010 59 12 3229 3239 10.2337/db10-0502
    • (2010) Diabetes , vol.59 , Issue.12 , pp. 3229-3239
    • Soranzo, N.1    Sanna, S.2    Wheeler, E.3
  • 79
    • 84870389491 scopus 로고    scopus 로고
    • GRK5 ablation contributes to insulin resistance
    • 10.1016/j.bbrc.2012.10.077
    • Wang L., Shen M., Wang F., GRK5 ablation contributes to insulin resistance. Biochemical and Biophysical Research Communications 2012 429 1-2 99 104 10.1016/j.bbrc.2012.10.077
    • (2012) Biochemical and Biophysical Research Communications , vol.429 , Issue.1-2 , pp. 99-104
    • Wang, L.1    Shen, M.2    Wang, F.3
  • 80
    • 0347722280 scopus 로고    scopus 로고
    • The concerted activities of PAX4 and Nkx2.2 are essential to initiate pancreatic β -cell differentiation
    • 2-s2.0-0347722280 10.1016/j.ydbio.2003.10.018
    • Wang J., Elghazi L., Parker S. E., Kizilocak H., Asano M., Sussel L., Sosa-Pineda B., The concerted activities of PAX4 and Nkx2.2 are essential to initiate pancreatic β -cell differentiation. Developmental Biology 2004 266 1 178 189 2-s2.0-0347722280 10.1016/j.ydbio.2003.10.018
    • (2004) Developmental Biology , vol.266 , Issue.1 , pp. 178-189
    • Wang, J.1    Elghazi, L.2    Parker, S.E.3    Kizilocak, H.4    Asano, M.5    Sussel, L.6    Sosa-Pineda, B.7
  • 81
    • 0028139089 scopus 로고
    • Positional cloning of the mouse obese gene and its human homologue
    • 2-s2.0-0028139089 10.1038/372425a0
    • Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., Friedman J. M., Positional cloning of the mouse obese gene and its human homologue. Nature 1994 372 6505 425 432 2-s2.0-0028139089 10.1038/372425a0
    • (1994) Nature , vol.372 , Issue.6505 , pp. 425-432
    • Zhang, Y.1    Proenca, R.2    Maffei, M.3    Barone, M.4    Leopold, L.5    Friedman, J.M.6
  • 82
    • 53549096229 scopus 로고    scopus 로고
    • Positive association between variations in CDKAL1 and type 2 diabetes in Han Chinese individuals
    • 2-s2.0-53549096229 10.1007/s00125-008-1141-6
    • Liu Y., Yu L., Zhang D., Chen Z., Zhou D. Z., Zhao T., Li S., Wang T., Hu X., Feng G. Y., Zhang Z. F., He L., Xu H., Positive association between variations in CDKAL1 and type 2 diabetes in Han Chinese individuals. Diabetologia 2008 51 11 2134 2137 2-s2.0-53549096229 10.1007/s00125-008-1141-6
    • (2008) Diabetologia , vol.51 , Issue.11 , pp. 2134-2137
    • Liu, Y.1    Yu, L.2    Zhang, D.3    Chen, Z.4    Zhou, D.Z.5    Zhao, T.6    Li, S.7    Wang, T.8    Hu, X.9    Feng, G.Y.10    Zhang, Z.F.11    He, L.12    Xu, H.13
  • 83
    • 78649526616 scopus 로고    scopus 로고
    • Combined effects of 19 common variations on type 2 diabetes in Chinese: Results from two community-based studies
    • 2-s2.0-78649526616 10.1371/journal.pone.0014022 e14022
    • Xu M., Bi Y., Xu Y., Yu B., Huang Y., Gu L., Wu Y., Zhu X., Li M., Wang T., Song A., Hou J., Li X., Ning G., Combined effects of 19 common variations on type 2 diabetes in Chinese: results from two community-based studies. PLoS ONE 2010 5 11 2-s2.0-78649526616 10.1371/journal.pone.0014022 e14022
    • (2010) PLoS ONE , vol.5 , Issue.11
    • Xu, M.1    Bi, Y.2    Xu, Y.3    Yu, B.4    Huang, Y.5    Gu, L.6    Wu, Y.7    Zhu, X.8    Li, M.9    Wang, T.10    Song, A.11    Hou, J.12    Li, X.13    Ning, G.14
  • 84
    • 56349170898 scopus 로고    scopus 로고
    • Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population
    • 2-s2.0-56349170898 10.2337/db08-0047
    • Wu Y., Li H., Loos R. J. F., Yu Z., Ye X., Chen L., Pan A., Hu F. B., Lin X., Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population. Diabetes 2008 57 10 2834 2842 2-s2.0-56349170898 10.2337/db08-0047
    • (2008) Diabetes , vol.57 , Issue.10 , pp. 2834-2842
    • Wu, Y.1    Li, H.2    Loos, R.J.F.3    Yu, Z.4    Ye, X.5    Chen, L.6    Pan, A.7    Hu, F.B.8    Lin, X.9
  • 85
    • 77955051399 scopus 로고    scopus 로고
    • Meta-analysis added power to identify variants in FTO associated with type 2 diabetes and obesity in the Asian population
    • 2-s2.0-77955051399 10.1038/oby.2009.469
    • Liu Y., Liu Z., Song Y., Zhou D., Zhang D., Zhao T., Chen Z., Yu L., Yang Y., Feng G., Li J., Zhang J., Liu S., Zhang Z., He L., Xu H., Meta-analysis added power to identify variants in FTO associated with type 2 diabetes and obesity in the Asian population. Obesity 2010 18 8 1619 1624 2-s2.0-77955051399 10.1038/oby.2009.469
    • (2010) Obesity , vol.18 , Issue.8 , pp. 1619-1624
    • Liu, Y.1    Liu, Z.2    Song, Y.3    Zhou, D.4    Zhang, D.5    Zhao, T.6    Chen, Z.7    Yu, L.8    Yang, Y.9    Feng, G.10    Li, J.11    Zhang, J.12    Liu, S.13    Zhang, Z.14    He, L.15    Xu, H.16
  • 86
    • 77949346987 scopus 로고    scopus 로고
    • Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort
    • 2-s2.0-77949346987 10.1371/journal.pone.0009153 e9153
    • Wen J., Rönn T., Olsson A., Yang Z., Lu B., Du Y., Groop L., Ling C., Hu R., Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort. PLoS ONE 2010 5 2 2-s2.0-77949346987 10.1371/journal.pone.0009153 e9153
    • (2010) PLoS ONE , vol.5 , Issue.2
    • Wen, J.1    Rönn, T.2    Olsson, A.3    Yang, Z.4    Lu, B.5    Du, Y.6    Groop, L.7    Ling, C.8    Hu, R.9
  • 87
    • 70449433016 scopus 로고    scopus 로고
    • PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a chinese population
    • 2-s2.0-70449433016 10.1371/journal.pone.0007643 e7643
    • Hu C., Zhang R., Wang C., Wang J., Ma X., Lu J., Qin W., Hou X., Wang C., Bao Y., Xiang K., Jia W., PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a chinese population. PLoS ONE 2009 4 10 2-s2.0-70449433016 10.1371/journal.pone.0007643 e7643
    • (2009) PLoS ONE , vol.4 , Issue.10
    • Hu, C.1    Zhang, R.2    Wang, C.3    Wang, J.4    Ma, X.5    Lu, J.6    Qin, W.7    Hou, X.8    Wang, C.9    Bao, Y.10    Xiang, K.11    Jia, W.12
  • 89
    • 64149094603 scopus 로고    scopus 로고
    • A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals
    • 2-s2.0-64149094603 10.1007/s00125-009-1297-8
    • Rönn T., Wen J., Yang Z., Lu B., Du Y., Groop L., Hu R., Ling C., A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals. Diabetologia 2009 52 5 830 833 2-s2.0-64149094603 10.1007/s00125-009-1297-8
    • (2009) Diabetologia , vol.52 , Issue.5 , pp. 830-833
    • Rönn, T.1    Wen, J.2    Yang, Z.3    Lu, B.4    Du, Y.5    Groop, L.6    Hu, R.7    Ling, C.8
  • 90
    • 34548765645 scopus 로고    scopus 로고
    • Replication and identification of novel variants at TCF7L2 associated with type 2 diabetes in Hong Kong Chinese
    • 2-s2.0-34548765645 10.1210/jc.2007-0849
    • Ng M. C. Y., Tam C. H. T., Lam V. K. L., So W.-Y., Ma R. C. W., Chan J. C. N., Replication and identification of novel variants at TCF7L2 associated with type 2 diabetes in Hong Kong Chinese. The Journal of Clinical Endocrinology & Metabolism 2007 92 9 3733 3737 2-s2.0-34548765645 10.1210/jc.2007-0849
    • (2007) The Journal of Clinical Endocrinology & Metabolism , vol.92 , Issue.9 , pp. 3733-3737
    • Ng, M.C.Y.1    Tam, C.H.T.2    Lam, V.K.L.3    So, W.-Y.4    Ma, R.C.W.5    Chan, J.C.N.6
  • 91
    • 50449104632 scopus 로고    scopus 로고
    • Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians
    • 2-s2.0-50449104632 10.2337/db07-1583
    • Ng M. C. Y., Park K. S., Oh B., Tam C. H. T., Cho Y. M., Shin H. D., Lam V. K. L., Ma R. C. W., So W. Y., Cho Y. S., Kim H.-L., Lee H. K., Chan J. C. N., Cho N. H., Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians. Diabetes 2008 57 8 2226 2233 2-s2.0-50449104632 10.2337/db07-1583
    • (2008) Diabetes , vol.57 , Issue.8 , pp. 2226-2233
    • Ng, M.C.Y.1    Park, K.S.2    Oh, B.3    Tam, C.H.T.4    Cho, Y.M.5    Shin, H.D.6    Lam, V.K.L.7    Ma, R.C.W.8    So, W.Y.9    Cho, Y.S.10    Kim, H.-L.11    Lee, H.K.12    Chan, J.C.N.13    Cho, N.H.14
  • 92
    • 34948845069 scopus 로고    scopus 로고
    • Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population
    • 2-s2.0-34948845069 10.2337/db07-0421
    • Chang Y.-C., Chang T.-J., Jiang Y.-D., Kuo S.-S., Lee K.-C., Chiu K. C., Chuang L.-M., Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population. Diabetes 2007 56 10 2631 2637 2-s2.0-34948845069 10.2337/db07-0421
    • (2007) Diabetes , vol.56 , Issue.10 , pp. 2631-2637
    • Chang, Y.-C.1    Chang, T.-J.2    Jiang, Y.-D.3    Kuo, S.-S.4    Lee, K.-C.5    Chiu, K.C.6    Chuang, L.-M.7
  • 93
    • 84866946023 scopus 로고    scopus 로고
    • A single nucleotide polymorphism within DUSP9 is associated with susceptibility to type 2 diabetes in a Japanese population
    • 10.1371/journal.pone.0046263 e46263
    • Fukuda H., Imamura M., Tanaka Y., A single nucleotide polymorphism within DUSP9 is associated with susceptibility to type 2 diabetes in a Japanese population. PLoS One 2012 7 9 10.1371/journal.pone.0046263 e46263
    • (2012) PLoS One , vol.7 , Issue.9
    • Fukuda, H.1    Imamura, M.2    Tanaka, Y.3
  • 94
    • 1842558762 scopus 로고    scopus 로고
    • Cardiovascular and infectious diseases in South Asia: The double whammy
    • 2-s2.0-1842558762 10.1136/bmj.328.7443.781
    • Basnyat B., Rajapaksa L. C., Cardiovascular and infectious diseases in South Asia: the double whammy. British Medical Journal 2004 328 7443 781 2-s2.0-1842558762 10.1136/bmj.328.7443.781
    • (2004) British Medical Journal , vol.328 , Issue.7443 , pp. 781
    • Basnyat, B.1    Rajapaksa, L.C.2
  • 96
    • 75149176607 scopus 로고    scopus 로고
    • Diabetes in Asia
    • 2-s2.0-75149176607 10.1016/S0140-6736(09)60937-5
    • Ramachandran A., Ma R. C., Snehalatha C., Diabetes in Asia. The Lancet 2010 375 9712 408 418 2-s2.0-75149176607 10.1016/S0140-6736(09)60937-5
    • (2010) The Lancet , vol.375 , Issue.9712 , pp. 408-418
    • Ramachandran, A.1    Ma, R.C.2    Snehalatha, C.3
  • 97
    • 0034639623 scopus 로고    scopus 로고
    • Plasma homocysteine concentrations and risk of coronary heart disease in UK Indian Asian and European men
    • 2-s2.0-0034639623
    • Chambers J. C., Obeid O. A., Refsum H., Ueland P., Hackett D., Hooper J., Turner R. M., Thompson S. G., Kooner J. S., Plasma homocysteine concentrations and risk of coronary heart disease in UK Indian Asian and European men. The Lancet 2000 355 9203 523 527 2-s2.0-0034639623
    • (2000) The Lancet , vol.355 , Issue.9203 , pp. 523-527
    • Chambers, J.C.1    Obeid, O.A.2    Refsum, H.3    Ueland, P.4    Hackett, D.5    Hooper, J.6    Turner, R.M.7    Thompson, S.G.8    Kooner, J.S.9
  • 98
    • 47749128415 scopus 로고    scopus 로고
    • Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk
    • 2-s2.0-47749128415 10.1186/1471-2350-9-59
    • Sanghera D. K., Ortega L., Han S., Singh J., Ralhan S. K., Wander G. S., Mehra N. K., Mulvihill J. J., Ferrell R. E., Nath S. K., Kamboh M. I., Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk. BMC Medical Genetics 2008 9, article 59 2-s2.0-47749128415 10.1186/1471-2350-9-59
    • (2008) BMC Medical Genetics , vol.959
    • Sanghera, D.K.1    Ortega, L.2    Han, S.3    Singh, J.4    Ralhan, S.K.5    Wander, G.S.6    Mehra, N.K.7    Mulvihill, J.J.8    Ferrell, R.E.9    Nath, S.K.10    Kamboh, M.I.11
  • 100
    • 78549232589 scopus 로고    scopus 로고
    • Replication of recently described type 2 diabetes gene variants in a South Indian population
    • 2-s2.0-78549232589 10.1016/j.metabol.2010.04.024
    • Chidambaram M., Radha V., Mohan V., Replication of recently described type 2 diabetes gene variants in a South Indian population. Metabolism 2010 59 12 1760 1766 2-s2.0-78549232589 10.1016/j.metabol.2010.04.024
    • (2010) Metabolism , vol.59 , Issue.12 , pp. 1760-1766
    • Chidambaram, M.1    Radha, V.2    Mohan, V.3
  • 102
    • 80052517091 scopus 로고    scopus 로고
    • Replication of 13 genome-wide association (GWA)-validated risk variants for type 2 diabetes in Pakistani populations
    • 2-s2.0-80052517091 10.1007/s00125-011-2063-2
    • Rees S. D., Hydrie M. Z. I., Shera A. S., Kumar S., O'Hare J. P., Barnett A. H., Basit A., Kelly M. A., Replication of 13 genome-wide association (GWA)-validated risk variants for type 2 diabetes in Pakistani populations. Diabetologia 2011 54 6 1368 1374 2-s2.0-80052517091 10.1007/s00125-011-2063-2
    • (2011) Diabetologia , vol.54 , Issue.6 , pp. 1368-1374
    • Rees, S.D.1    Hydrie, M.Z.I.2    Shera, A.S.3    Kumar, S.4    O'Hare, J.P.5    Barnett, A.H.6    Basit, A.7    Kelly, M.A.8
  • 103
    • 34248162419 scopus 로고    scopus 로고
    • Variants in ARHGEF11, a candidate gene for the linkage to type 2 diabetes on chromosome 1q, are nominally associated with insulin resistance and type 2 diabetes in Pima Indians
    • 2-s2.0-34248162419 10.2337/db06-0640
    • Ma L., Hanson R. L., Que L. N., Cali A. M. G., Fu M., Mack J. L., Infante A. M., Kobes S., Bogardus C., Shuldiner A. R., Baier L. J., Variants in ARHGEF11, a candidate gene for the linkage to type 2 diabetes on chromosome 1q, are nominally associated with insulin resistance and type 2 diabetes in Pima Indians. Diabetes 2007 56 5 1454 1459 2-s2.0-34248162419 10.2337/db06-0640
    • (2007) Diabetes , vol.56 , Issue.5 , pp. 1454-1459
    • Ma, L.1    Hanson, R.L.2    Que, L.N.3    Cali, A.M.G.4    Fu, M.5    Mack, J.L.6    Infante, A.M.7    Kobes, S.8    Bogardus, C.9    Shuldiner, A.R.10    Baier, L.J.11
  • 104
    • 58149333719 scopus 로고    scopus 로고
    • PCLO variants are nominally associated with early-onset type 2 diabetes and insulin resistance in Pima Indians
    • 2-s2.0-58149333719 10.2337/db07-1800
    • Ma L., Hanson R. L., Que L. N., Guo Y., Kobes S., Bogardus C., Baier L. J., PCLO variants are nominally associated with early-onset type 2 diabetes and insulin resistance in Pima Indians. Diabetes 2008 57 11 3156 3160 2-s2.0-58149333719 10.2337/db07-1800
    • (2008) Diabetes , vol.57 , Issue.11 , pp. 3156-3160
    • Ma, L.1    Hanson, R.L.2    Que, L.N.3    Guo, Y.4    Kobes, S.5    Bogardus, C.6    Baier, L.J.7
  • 105
    • 77955657911 scopus 로고    scopus 로고
    • Variants in ACAD10 are associated with type 2 diabetes, insulin resistance and lipid oxidation in Pima Indians
    • 2-s2.0-77955657911 10.1007/s00125-010-1695-y
    • Bian L., Hanson R. L., Muller Y. L., Ma L., Kobes S., Knowler W. C., Bogardus C., Baier L. J., Variants in ACAD10 are associated with type 2 diabetes, insulin resistance and lipid oxidation in Pima Indians. Diabetologia 2010 53 7 1349 1353 2-s2.0-77955657911 10.1007/s00125-010-1695-y
    • (2010) Diabetologia , vol.53 , Issue.7 , pp. 1349-1353
    • Bian, L.1    Hanson, R.L.2    Muller, Y.L.3    Ma, L.4    Kobes, S.5    Knowler, W.C.6    Bogardus, C.7    Baier, L.J.8
  • 106
    • 77951784610 scopus 로고    scopus 로고
    • Variants in ASK1 are associated with skeletal muscle ASK1 expression, in vivo insulin resistance, and type 2 diabetes in Pima Indians
    • 2-s2.0-77951784610 10.2337/db09-1700
    • Bian L., Hanson R. L., Ossowski V., Wiedrich K., Mason C. C., Traurig M., Muller Y. L., Kobes S., Knowler W. C., Baier L. J., Bogardus C., Variants in ASK1 are associated with skeletal muscle ASK1 expression, in vivo insulin resistance, and type 2 diabetes in Pima Indians. Diabetes 2010 59 5 1276 1282 2-s2.0-77951784610 10.2337/db09-1700
    • (2010) Diabetes , vol.59 , Issue.5 , pp. 1276-1282
    • Bian, L.1    Hanson, R.L.2    Ossowski, V.3    Wiedrich, K.4    Mason, C.C.5    Traurig, M.6    Muller, Y.L.7    Kobes, S.8    Knowler, W.C.9    Baier, L.J.10    Bogardus, C.11
  • 107
    • 63249107785 scopus 로고    scopus 로고
    • Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians
    • 2-s2.0-63249107785 10.2337/db08-0877
    • Rong R., Hanson R. L., Ortiz D., Wiedrich C., Kobes S., Knowler W. C., Bogardus C., Baier L. J., Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians. Diabetes 2009 58 2 478 488 2-s2.0-63249107785 10.2337/db08-0877
    • (2009) Diabetes , vol.58 , Issue.2 , pp. 478-488
    • Rong, R.1    Hanson, R.L.2    Ortiz, D.3    Wiedrich, C.4    Kobes, S.5    Knowler, W.C.6    Bogardus, C.7    Baier, L.J.8
  • 109
    • 79960923810 scopus 로고    scopus 로고
    • Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals
    • 2-s2.0-79960923810 10.1007/s00125-011-2188-3
    • Below J. E., Gamazon E. R., Morrison J. V., Konkashbaev A., Pluzhnikov A., McKeigue P. M., Parra E. J., Elbein S. C., Hallman D. M., Nicolae D. L., Bell G. I., Cruz M., Cox N. J., Hanis C. L., Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals. Diabetologia 2011 54 8 2047 2055 2-s2.0-79960923810 10.1007/s00125-011-2188-3
    • (2011) Diabetologia , vol.54 , Issue.8 , pp. 2047-2055
    • Below, J.E.1    Gamazon, E.R.2    Morrison, J.V.3    Konkashbaev, A.4    Pluzhnikov, A.5    McKeigue, P.M.6    Parra, E.J.7    Elbein, S.C.8    Hallman, D.M.9    Nicolae, D.L.10    Bell, G.I.11    Cruz, M.12    Cox, N.J.13    Hanis, C.L.14
  • 110
    • 84893716900 scopus 로고    scopus 로고
    • Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico
    • 10.1038/nature12828
    • Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. Nature 2013 506 97 101 10.1038/nature12828
    • (2013) Nature , vol.506 , pp. 97-101
  • 112
    • 77955509318 scopus 로고    scopus 로고
    • Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people
    • 2-s2.0-77955509318 10.1007/s00125-010-1753-5
    • Boesgaard T. W., Grarup N., Jørgensen T., Borch-Johnsen K., Hansen T., Pedersen O., Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people. Diabetologia 2010 53 8 1647 1655 2-s2.0-77955509318 10.1007/s00125-010-1753-5
    • (2010) Diabetologia , vol.53 , Issue.8 , pp. 1647-1655
    • Boesgaard, T.W.1    Grarup, N.2    Jørgensen, T.3    Borch-Johnsen, K.4    Hansen, T.5    Pedersen, O.6
  • 113
    • 79954632738 scopus 로고    scopus 로고
    • Type 2 diabetes risk allele near CENTD2 is associated with decreased glucose-stimulated insulin release
    • 2-s2.0-79954632738 10.1007/s00125-011-2054-3
    • Nielsen T., Sparsø T., Grarup N., Jørgensen T., Pisinger C., Witte D. R., Hansen T., Pedersen O., Type 2 diabetes risk allele near CENTD2 is associated with decreased glucose-stimulated insulin release. Diabetologia 2011 54 5 1052 1056 2-s2.0-79954632738 10.1007/s00125-011-2054-3
    • (2011) Diabetologia , vol.54 , Issue.5 , pp. 1052-1056
    • Nielsen, T.1    Sparsø, T.2    Grarup, N.3    Jørgensen, T.4    Pisinger, C.5    Witte, D.R.6    Hansen, T.7    Pedersen, O.8
  • 114
    • 80052939674 scopus 로고    scopus 로고
    • Effects of 16 genetic variants on fasting glucose and type 2 diabetes in South Asians: ADCY5 and GLIS3 variants may predispose to type 2 diabetes
    • 2-s2.0-80052939674 10.1371/journal.pone.0024710 e24710
    • Rees S. D., Hydrie M. Z. I., O'Hare J. P., Kumar S., Shera A. S., Basit A., Barnett A. H., Kelly M. A., Effects of 16 genetic variants on fasting glucose and type 2 diabetes in South Asians: ADCY5 and GLIS3 variants may predispose to type 2 diabetes. PLoS ONE 2011 6 9 2-s2.0-80052939674 10.1371/journal.pone.0024710 e24710
    • (2011) PLoS ONE , vol.6 , Issue.9
    • Rees, S.D.1    Hydrie, M.Z.I.2    O'Hare, J.P.3    Kumar, S.4    Shera, A.S.5    Basit, A.6    Barnett, A.H.7    Kelly, M.A.8
  • 116
    • 0034069653 scopus 로고    scopus 로고
    • In vivo modulation of Hmgic reduces obesity
    • 2-s2.0-0034069653 10.1038/74207
    • Anand A., Chada K., In vivo modulation of Hmgic reduces obesity. Nature Genetics 2000 24 4 377 380 2-s2.0-0034069653 10.1038/74207
    • (2000) Nature Genetics , vol.24 , Issue.4 , pp. 377-380
    • Anand, A.1    Chada, K.2
  • 117
    • 84872410740 scopus 로고    scopus 로고
    • Association of the common FTO -rs9939609 polymorphism with type 2 diabetes, independent of obesity-related traits in a Vietnamese population
    • 10.1016/j.gene.2012.10.082
    • Binh T. Q., Phuong P. T., Nhung B. T., Association of the common FTO -rs9939609 polymorphism with type 2 diabetes, independent of obesity-related traits in a Vietnamese population. Gene 2013 513 1 31 35 10.1016/j.gene.2012.10. 082
    • (2013) Gene , vol.513 , Issue.1 , pp. 31-35
    • Binh, T.Q.1    Phuong, P.T.2    Nhung, B.T.3
  • 118
    • 84866110736 scopus 로고    scopus 로고
    • Common polymorphism near the MC4R gene is associated with type 2 diabetes: Data from a meta-analysis of 123, 373 individuals
    • Xi B., Takeuchi F., Chandak G. R., Common polymorphism near the MC4R gene is associated with type 2 diabetes: data from a meta-analysis of 123, 373 individuals. Diabetologia 2012 55 10 2660 2666
    • (2012) Diabetologia , vol.55 , Issue.10 , pp. 2660-2666
    • Xi, B.1    Takeuchi, F.2    Chandak, G.R.3
  • 120
    • 77449099615 scopus 로고    scopus 로고
    • TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action
    • 2-s2.0-77449099615 10.2337/db09-1169
    • Villareal D. T., Robertson H., Bell G. I., Patterson B. W., Tran H., Wice B., Polonsky K. S., TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action. Diabetes 2010 59 2 479 485 2-s2.0-77449099615 10.2337/db09-1169
    • (2010) Diabetes , vol.59 , Issue.2 , pp. 479-485
    • Villareal, D.T.1    Robertson, H.2    Bell, G.I.3    Patterson, B.W.4    Tran, H.5    Wice, B.6    Polonsky, K.S.7
  • 121
    • 84866072918 scopus 로고    scopus 로고
    • TCF7L2 rs7903146 impairs islet function and morphology in non-diabetic individuals
    • 10.1007/s00125-012-2660-8
    • le Bacquer O., Kerr-Conte J., Gargani S., TCF7L2 rs7903146 impairs islet function and morphology in non-diabetic individuals. Diabetologia 2012 55 10 2677 2681 10.1007/s00125-012-2660-8
    • (2012) Diabetologia , vol.55 , Issue.10 , pp. 2677-2681
    • Le Bacquer, O.1    Kerr-Conte, J.2    Gargani, S.3
  • 122
    • 84856711643 scopus 로고    scopus 로고
    • Reduction of both β cell death and alpha cell proliferation by dipeptidyl peptidase-4 inhibition in a streptozotocin-induced model of diabetes in mice
    • 2-s2.0-84856711643 10.1007/s00125-011-2365-4
    • Takeda Y., Fujita Y., Honjo J., Yanagimachi T., Sakagami H., Takiyama Y., Makino Y., Abiko A., Kieffer T. J., Haneda M., Reduction of both β cell death and alpha cell proliferation by dipeptidyl peptidase-4 inhibition in a streptozotocin-induced model of diabetes in mice. Diabetologia 2012 55 2 404 412 2-s2.0-84856711643 10.1007/s00125-011-2365-4
    • (2012) Diabetologia , vol.55 , Issue.2 , pp. 404-412
    • Takeda, Y.1    Fujita, Y.2    Honjo, J.3    Yanagimachi, T.4    Sakagami, H.5    Takiyama, Y.6    Makino, Y.7    Abiko, A.8    Kieffer, T.J.9    Haneda, M.10
  • 123
    • 0038707331 scopus 로고    scopus 로고
    • Selective β -cell loss and α -cell expansion in patients with type 2 diabetes mellitus in Korea
    • 10.1210/jc.2002-020735
    • Yoon K. H., Ko S. H., Cho J. H., Selective β -cell loss and α -cell expansion in patients with type 2 diabetes mellitus in Korea. The Journal of Clinical Endocrinology & Metabolism 2003 88 5 2300 2308 10.1210/jc.2002-020735
    • (2003) The Journal of Clinical Endocrinology & Metabolism , vol.88 , Issue.5 , pp. 2300-2308
    • Yoon, K.H.1    Ko, S.H.2    Cho, J.H.3
  • 124
    • 77955261951 scopus 로고    scopus 로고
    • Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: Correlations with age or BMI of islet donors
    • e11053 2-s2.0-77956197973 10.1371/journal.pone.0011053
    • Kirkpatrick C. L., Marchetti P., Purrello F., Piro S., Bugliani M., Bosco D., de Koning E. J. P., Engelse M. A., Kerr-Conte J., Pattou F., Wollheim C. B., Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors. PLoS ONE 2010 5 6 e11053 2-s2.0-77956197973 10.1371/journal.pone.0011053
    • (2010) PLoS ONE , vol.5 , Issue.6
    • Kirkpatrick, C.L.1    Marchetti, P.2    Purrello, F.3    Piro, S.4    Bugliani, M.5    Bosco, D.6    De Koning, E.J.P.7    Engelse, M.A.8    Kerr-Conte, J.9    Pattou, F.10    Wollheim, C.B.11
  • 125
    • 0031848068 scopus 로고    scopus 로고
    • Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
    • 2-s2.0-0031848068 10.1038/1270
    • Korinek V., Barker N., Moerer P., van Donselaar E., Huls G., Peters P. J., Clevers H., Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nature Genetics 1998 19 4 379 383 2-s2.0-0031848068 10.1038/1270
    • (1998) Nature Genetics , vol.19 , Issue.4 , pp. 379-383
    • Korinek, V.1    Barker, N.2    Moerer, P.3    Van Donselaar, E.4    Huls, G.5    Peters, P.J.6    Clevers, H.7
  • 126
    • 84867191630 scopus 로고    scopus 로고
    • The involvement of the Wnt signaling pathway and TCF7L2 in diabetes mellitus: The current understanding, dispute, and perspective
    • 10.1186/2045-3701-2-28
    • Ip W., Chiang Y. T., Jin T., The involvement of the Wnt signaling pathway and TCF7L2 in diabetes mellitus: the current understanding, dispute, and perspective. Cell & Bioscience 2012 2 1, article 28 10.1186/2045-3701-2-28
    • (2012) Cell & Bioscience , vol.2 , Issue.1
    • Ip, W.1    Chiang, Y.T.2    Jin, T.3
  • 127
    • 24944487996 scopus 로고    scopus 로고
    • Pancreas-specific deletion of β -catenin reveals Wnt-dependent and Wnt-independent functions during development
    • 2-s2.0-24944487996 10.1016/j.cub.2005.08.037
    • Dessimoz J., Bonnard C., Huelsken J., Grapin-Botton A., Pancreas-specific deletion of β -catenin reveals Wnt-dependent and Wnt-independent functions during development. Current Biology 2005 15 18 1677 1683 2-s2.0-24944487996 10.1016/j.cub.2005.08.037
    • (2005) Current Biology , vol.15 , Issue.18 , pp. 1677-1683
    • Dessimoz, J.1    Bonnard, C.2    Huelsken, J.3    Grapin-Botton, A.4
  • 128
    • 28044449357 scopus 로고    scopus 로고
    • β -catenin is essential for pancreatic acinar but not islet development
    • 2-s2.0-28044449357 10.1242/dev.02063
    • Murtaugh L. C., Law A. C., Dor Y., Melton D. A., β -catenin is essential for pancreatic acinar but not islet development. Development 2005 132 21 4663 4674 2-s2.0-28044449357 10.1242/dev.02063
    • (2005) Development , vol.132 , Issue.21 , pp. 4663-4674
    • Murtaugh, L.C.1    Law, A.C.2    Dor, Y.3    Melton, D.A.4
  • 129
    • 25844530871 scopus 로고    scopus 로고
    • Attenuated Wnt signaling perturbs pancreatic growth but not pancreatic function
    • 2-s2.0-25844530871 10.2337/diabetes.54.10.2844
    • Papadopoulou S., Edlund H., Attenuated Wnt signaling perturbs pancreatic growth but not pancreatic function. Diabetes 2005 54 10 2844 2851 2-s2.0-25844530871 10.2337/diabetes.54.10.2844
    • (2005) Diabetes , vol.54 , Issue.10 , pp. 2844-2851
    • Papadopoulou, S.1    Edlund, H.2
  • 130
    • 33745084564 scopus 로고    scopus 로고
    • Stabilization of β -catenin impacts pancreas growth
    • 2-s2.0-33745084564 10.1242/dev.02366
    • Heiser P. W., Lau J., Taketo M. M., Herrera P. L., Hebrok M., Stabilization of β -catenin impacts pancreas growth. Development 2006 133 10 2023 2032 2-s2.0-33745084564 10.1242/dev.02366
    • (2006) Development , vol.133 , Issue.10 , pp. 2023-2032
    • Heiser, P.W.1    Lau, J.2    Taketo, M.M.3    Herrera, P.L.4    Hebrok, M.5
  • 131
    • 0036842027 scopus 로고    scopus 로고
    • Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation
    • 2-s2.0-0036842027 10.1002/dvdy.10157
    • Heller R. S., Dichmann D. S., Jensen J., Miller C., Wong G., Madsen O. D., Serup P., Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation. Developmental Dynamics 2002 225 3 260 270 2-s2.0-0036842027 10.1002/dvdy.10157
    • (2002) Developmental Dynamics , vol.225 , Issue.3 , pp. 260-270
    • Heller, R.S.1    Dichmann, D.S.2    Jensen, J.3    Miller, C.4    Wong, G.5    Madsen, O.D.6    Serup, P.7
  • 133
    • 84871596296 scopus 로고    scopus 로고
    • Diabetes risk gene and Wnt effector TCF7L2 /TCF4 controls hepatic response to perinatal and adult metabolic demand
    • 10.1016/j.cell.2012.10.053
    • Boj S. F., van Es J. H., Huch M., Diabetes risk gene and Wnt effector TCF7L2 /TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell 2012 151 7 1595 1607 10.1016/j.cell.2012.10.053
    • (2012) Cell , vol.151 , Issue.7 , pp. 1595-1607
    • Boj, S.F.1    Van Es, J.H.2    Huch, M.3
  • 134
    • 24744451161 scopus 로고    scopus 로고
    • ZnT-8, a pancreatic β -cell-specific zinc transporter
    • 2-s2.0-24744451161 10.1007/s10534-005-3687-9
    • Chimienti F., Favier A., Seve M., ZnT-8, a pancreatic β -cell-specific zinc transporter. Biometals 2005 18 4 313 317 2-s2.0-24744451161 10.1007/s10534-005-3687-9
    • (2005) Biometals , vol.18 , Issue.4 , pp. 313-317
    • Chimienti, F.1    Favier, A.2    Seve, M.3
  • 135
    • 77955518148 scopus 로고    scopus 로고
    • Downregulation of ZnT8 expression in pancreatic β -cells of diabetic mice
    • 2-s2.0-77955518148
    • Tamaki M., Fujitani Y., Uchida T., Hirose T., Kawamori R., Watada H., Downregulation of ZnT8 expression in pancreatic β -cells of diabetic mice. Islets 2009 1 2 124 128 2-s2.0-77955518148
    • (2009) Islets , vol.1 , Issue.2 , pp. 124-128
    • Tamaki, M.1    Fujitani, Y.2    Uchida, T.3    Hirose, T.4    Kawamori, R.5    Watada, H.6
  • 137
    • 84885050266 scopus 로고    scopus 로고
    • The diabetes-susceptible gene SLC30A8 /ZnT8 regulates hepatic insulin clearance
    • 10.1172/JCI68807
    • Tamaki M., Fujitani Y., Hara A., The diabetes-susceptible gene SLC30A8 /ZnT8 regulates hepatic insulin clearance. The Journal of Clinical Investigation 2013 123 10 4513 4524 10.1172/JCI68807
    • (2013) The Journal of Clinical Investigation , vol.123 , Issue.10 , pp. 4513-4524
    • Tamaki, M.1    Fujitani, Y.2    Hara, A.3
  • 139
    • 79551470998 scopus 로고    scopus 로고
    • The pancreatic islet β -cell-enriched transcription factor Pdx-1 regulates Slc30a8 gene transcription through an intronic enhancer
    • 2-s2.0-79551470998 10.1042/BJ20101488
    • Pound L. D., Hang Y., Sarkar S. A., Wang Y., Milam L. A., Oeser J. K., Printz R. L., Lee C. E., Stein R., Hutton J. C., O'Brien R. M., The pancreatic islet β -cell-enriched transcription factor Pdx-1 regulates Slc30a8 gene transcription through an intronic enhancer. Biochemical Journal 2011 433 1 95 105 2-s2.0-79551470998 10.1042/BJ20101488
    • (2011) Biochemical Journal , vol.433 , Issue.1 , pp. 95-105
    • Pound, L.D.1    Hang, Y.2    Sarkar, S.A.3    Wang, Y.4    Milam, L.A.5    Oeser, J.K.6    Printz, R.L.7    Lee, C.E.8    Stein, R.9    Hutton, J.C.10    O'Brien, R.M.11
  • 140
    • 84865344371 scopus 로고    scopus 로고
    • Genetics of type 2 diabetes in European populations
    • 10.1111/j.1753-0407.2012.00224.x
    • Qi Q., Hu F. B., Genetics of type 2 diabetes in European populations. Journal of Diabetes 2012 4 3 203 212 10.1111/j.1753-0407.2012.00224.x
    • (2012) Journal of Diabetes , vol.4 , Issue.3 , pp. 203-212
    • Qi, Q.1    Hu, F.B.2
  • 141
    • 84885236294 scopus 로고    scopus 로고
    • Assessing the clinical utility of a genetic risk score constructed using 49 susceptibility alleles for type 2 diabetes in a Japanese population
    • 10.1210/jc.2012-3791
    • Imamura M., Shigemizu D., Tsunoda T., Assessing the clinical utility of a genetic risk score constructed using 49 susceptibility alleles for type 2 diabetes in a Japanese population. The Journal of Clinical Endocrinology & Metabolism 2013 98 10 1667 1673 10.1210/jc.2012-3791
    • (2013) The Journal of Clinical Endocrinology & Metabolism , vol.98 , Issue.10 , pp. 1667-1673
    • Imamura, M.1    Shigemizu, D.2    Tsunoda, T.3
  • 142
    • 84859068424 scopus 로고    scopus 로고
    • Genetic risk assessment of type 2 diabetes-associated polymorphisms in African Americans
    • 2-s2.0-84859068424 10.2337/dc11-0957
    • Cooke J. N., Ng M. C. Y., Palmer N. D., Hester J. M., Freedman B. I., Langefeld C. D., An S. S., Bowden D. W., Genetic risk assessment of type 2 diabetes-associated polymorphisms in African Americans. Diabetes Care 2012 35 2 287 292 2-s2.0-84859068424 10.2337/dc11-0957
    • (2012) Diabetes Care , vol.35 , Issue.2 , pp. 287-292
    • Cooke, J.N.1    Ng, M.C.Y.2    Palmer, N.D.3    Hester, J.M.4    Freedman, B.I.5    Langefeld, C.D.6    An, S.S.7    Bowden, D.W.8
  • 143
    • 84864383698 scopus 로고    scopus 로고
    • Genetic risk score constructed using 14 susceptibility alleles for type 2 diabetes is associated with the early onset of diabetes and may predict the future requirement of insulin injections among Japanese individuals
    • Iwata M., Maeda S., Kamura Y., Genetic risk score constructed using 14 susceptibility alleles for type 2 diabetes is associated with the early onset of diabetes and may predict the future requirement of insulin injections among Japanese individuals. Diabetes Care 2012 35 8 1763 1770
    • (2012) Diabetes Care , vol.35 , Issue.8 , pp. 1763-1770
    • Iwata, M.1    Maeda, S.2    Kamura, Y.3
  • 145
    • 79951715822 scopus 로고    scopus 로고
    • Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms
    • 2-s2.0-79951715822 10.2337/dc10-1265
    • de Miguel-Yanes J. M., Shrader P., Pencina M. J., Fox C. S., Manning A. K., Grant R. W., Dupuis J., Florez J. C., D'Agostino R. B., Cupples L. A., Meigs J. B., Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms. Diabetes Care 2011 34 1 121 125 2-s2.0-79951715822 10.2337/dc10-1265
    • (2011) Diabetes Care , vol.34 , Issue.1 , pp. 121-125
    • De Miguel-Yanes, J.M.1    Shrader, P.2    Pencina, M.J.3    Fox, C.S.4    Manning, A.K.5    Grant, R.W.6    Dupuis, J.7    Florez, J.C.8    D'Agostino, R.B.9    Cupples, L.A.10    Meigs, J.B.11
  • 146
    • 84864185305 scopus 로고    scopus 로고
    • Gene-environment interactions in the development of type 2 diabetes: Recent progress and continuing challenges
    • Cornelis M. C., Hu F. B., Gene-environment interactions in the development of type 2 diabetes: recent progress and continuing challenges. Annual Review of Nutrition 2012 32 245 259
    • (2012) Annual Review of Nutrition , vol.32 , pp. 245-259
    • Cornelis, M.C.1    Hu, F.B.2
  • 147
    • 79953174333 scopus 로고    scopus 로고
    • Genomics and drug response
    • 2-s2.0-79953174333 10.1056/NEJMra1010600
    • Wang L., McLeod H. L., Weinshilboum R. M., Genomics and drug response. The New England Journal of Medicine 2011 364 12 1144 1153 2-s2.0-79953174333 10.1056/NEJMra1010600
    • (2011) The New England Journal of Medicine , vol.364 , Issue.12 , pp. 1144-1153
    • Wang, L.1    McLeod, H.L.2    Weinshilboum, R.M.3
  • 148
    • 84873430927 scopus 로고    scopus 로고
    • Individualized therapy for type 2 diabetes: Clinical implications of pharmacogenetic data
    • Mannino G. C., Sesti G., Individualized therapy for type 2 diabetes: clinical implications of pharmacogenetic data. Molecular Diagnosis & Therapy 2012 16 5 285 302
    • (2012) Molecular Diagnosis & Therapy , vol.16 , Issue.5 , pp. 285-302
    • Mannino, G.C.1    Sesti, G.2
  • 149
    • 70450133969 scopus 로고    scopus 로고
    • Influence of genetic polymorphisms on the pharmacokinetics and pharmacodynamics of sulfonylurea drugs
    • 2-s2.0-70450133969 10.2174/138920009789375388
    • Xu H., Murray M., McLachlan A. J., Influence of genetic polymorphisms on the pharmacokinetics and pharmacodynamics of sulfonylurea drugs. Current Drug Metabolism 2009 10 6 643 658 2-s2.0-70450133969 10.2174/138920009789375388
    • (2009) Current Drug Metabolism , vol.10 , Issue.6 , pp. 643-658
    • Xu, H.1    Murray, M.2    McLachlan, A.J.3
  • 152
    • 56149106823 scopus 로고    scopus 로고
    • Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients
    • 2-s2.0-56149106823 10.2337/dc07-2248
    • Feng Y., Mao G., Ren X., Xing H., Tang G., Li Q., Li X., Sun L., Yang J., Ma W., Wang X., Xu X., Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients. Diabetes Care 2008 31 10 1939 1944 2-s2.0-56149106823 10.2337/dc07-2248
    • (2008) Diabetes Care , vol.31 , Issue.10 , pp. 1939-1944
    • Feng, Y.1    Mao, G.2    Ren, X.3    Xing, H.4    Tang, G.5    Li, Q.6    Li, X.7    Sun, L.8    Yang, J.9    Ma, W.10    Wang, X.11    Xu, X.12
  • 154
    • 67649088187 scopus 로고    scopus 로고
    • Effect of the Gly972Arg, SNP43 and Pro12Ala polymorphisms of the genes IRS1, CAPN10 and PPARG2 on secondary failure to sulphonylurea and metformin in patients with type 2 diabetes in Yucatán, México
    • 2-s2.0-67649088187
    • García-Escalante M. G., Suárez-Solís V. M., López-Ávila M. T. D. J., Pinto-Escalante D. D. C., Laviada-Molina H., Effect of the Gly972Arg, SNP43 and Pro12Ala polymorphisms of the genes IRS1, CAPN10 and PPARG2 on secondary failure to sulphonylurea and metformin in patients with type 2 diabetes in Yucatán, México. Investigacion Clinica 2009 50 1 65 76 2-s2.0-67649088187
    • (2009) Investigacion Clinica , vol.50 , Issue.1 , pp. 65-76
    • García-Escalante, M.G.1    Suárez-Solís, V.M.2    López-Ávila, M.T.D.J.3    Pinto-Escalante, D.D.C.4    Laviada-Molina, H.5
  • 155
    • 53049096127 scopus 로고    scopus 로고
    • Common variation in the NOS1AP gene is associated with reduced glucose-lowering effect and with increased mortality in users of sulfonylurea
    • 2-s2.0-53049096127 10.1097/FPC.0b013e328300e8c5
    • Becker M. L., Aarnoudse A.-J., Newton-Cheh C., Hofman A., Witteman J. C. M., Uitterlinden A. G., Visser L. E., Stricker B. H. C., Common variation in the NOS1AP gene is associated with reduced glucose-lowering effect and with increased mortality in users of sulfonylurea. Pharmacogenetics and Genomics 2008 18 7 591 597 2-s2.0-53049096127 10.1097/FPC.0b013e328300e8c5
    • (2008) Pharmacogenetics and Genomics , vol.18 , Issue.7 , pp. 591-597
    • Becker, M.L.1    Aarnoudse, A.-J.2    Newton-Cheh, C.3    Hofman, A.4    Witteman, J.C.M.5    Uitterlinden, A.G.6    Visser, L.E.7    Stricker, B.H.C.8
  • 156
    • 77958580853 scopus 로고    scopus 로고
    • Genetic variants of the insulin receptor substrate-1 are influencing the therapeutic efficacy of oral antidiabetics
    • 2-s2.0-77958580853 10.1111/j.1463-1326.2010.01301.x
    • Seeringer A., Parmar S., Fischer A., Altissimo B., Zondler L., Lebedeva E., Pitterle K., Roots I., Kirchheiner J., Genetic variants of the insulin receptor substrate-1 are influencing the therapeutic efficacy of oral antidiabetics. Diabetes, Obesity and Metabolism 2010 12 12 1106 1112 2-s2.0-77958580853 10.1111/j.1463-1326.2010.01301.x
    • (2010) Diabetes, Obesity and Metabolism , vol.12 , Issue.12 , pp. 1106-1112
    • Seeringer, A.1    Parmar, S.2    Fischer, A.3    Altissimo, B.4    Zondler, L.5    Lebedeva, E.6    Pitterle, K.7    Roots, I.8    Kirchheiner, J.9
  • 160
  • 161
    • 67849116869 scopus 로고    scopus 로고
    • Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus
    • 2-s2.0-67849116869 10.1038/tpj.2009.15
    • Becker M. L., Visser L. E., van Schaik R. H. N., Hofman A., Uitterlinden A. G., Stricker B. H. C., Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus. Pharmacogenomics Journal 2009 9 4 242 247 2-s2.0-67849116869 10.1038/tpj.2009.15
    • (2009) Pharmacogenomics Journal , vol.9 , Issue.4 , pp. 242-247
    • Becker, M.L.1    Visser, L.E.2    Van Schaik, R.H.N.3    Hofman, A.4    Uitterlinden, A.G.5    Stricker, B.H.C.6
  • 162
    • 81055140250 scopus 로고    scopus 로고
    • The pharmacogenetics of metformin and its impact on plasma metformin steady-state levels and glycosylated hemoglobin A1c
    • 2-s2.0-81055140250 10.1097/FPC.0b013e32834c0010
    • Christensen M. M. H., Brasch-Andersen C., Green H., Nielsen F., Damkier P., Beck-Nielsen H., Brosen K., The pharmacogenetics of metformin and its impact on plasma metformin steady-state levels and glycosylated hemoglobin A1c. Pharmacogenetics and Genomics 2011 21 12 837 850 2-s2.0-81055140250 10.1097/FPC.0b013e32834c0010
    • (2011) Pharmacogenetics and Genomics , vol.21 , Issue.12 , pp. 837-850
    • Christensen, M.M.H.1    Brasch-Andersen, C.2    Green, H.3    Nielsen, F.4    Damkier, P.5    Beck-Nielsen, H.6    Brosen, K.7
  • 163
    • 54249106729 scopus 로고    scopus 로고
    • Genetic variants of the organic cation transporter 2 influence the disposition of metformin
    • 2-s2.0-54249106729 10.1038/clpt.2008.61
    • Song I. S., Shin H. J., Shim E. J., Jung I. S., Kim W. Y., Shon J. H., Shin J. G., Genetic variants of the organic cation transporter 2 influence the disposition of metformin. Clinical Pharmacology & Therapeutics 2008 84 5 559 562 2-s2.0-54249106729 10.1038/clpt.2008.61
    • (2008) Clinical Pharmacology & Therapeutics , vol.84 , Issue.5 , pp. 559-562
    • Song, I.S.1    Shin, H.J.2    Shim, E.J.3    Jung, I.S.4    Kim, W.Y.5    Shon, J.H.6    Shin, J.G.7
  • 164
    • 62749133967 scopus 로고    scopus 로고
    • Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect of metformin in patients with diabetes: A preliminary study
    • 2-s2.0-62749133967 10.2337/db08-1028
    • Becker M. L., Visser L. E., van Schaik R. H. N., Hofman A., Uitterlinden A. G., Stricker B. H. C., Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect of metformin in patients with diabetes: a preliminary study. Diabetes 2009 58 3 745 749 2-s2.0-62749133967 10.2337/db08-1028
    • (2009) Diabetes , vol.58 , Issue.3 , pp. 745-749
    • Becker, M.L.1    Visser, L.E.2    Van Schaik, R.H.N.3    Hofman, A.4    Uitterlinden, A.G.5    Stricker, B.H.C.6
  • 168
    • 29244482237 scopus 로고    scopus 로고
    • Effect of genetic polymorphisms in cytochrome P450 (CYP) 2C9 and CYP2C8 on the pharmacokinetics of oral antidiabetic drugs: Clinical relevance
    • 2-s2.0-29244482237 10.2165/00003088-200544120-00002
    • Kirchheiner J., Roots I., Goldammer M., Rosenkranz B., Brockmöller J., Effect of genetic polymorphisms in cytochrome P450 (CYP) 2C9 and CYP2C8 on the pharmacokinetics of oral antidiabetic drugs: clinical relevance. Clinical Pharmacokinetics 2005 44 12 1209 1225 2-s2.0-29244482237 10.2165/00003088- 200544120-00002
    • (2005) Clinical Pharmacokinetics , vol.44 , Issue.12 , pp. 1209-1225
    • Kirchheiner, J.1    Roots, I.2    Goldammer, M.3    Rosenkranz, B.4    Brockmöller, J.5
  • 169
    • 84877147862 scopus 로고    scopus 로고
    • Effect of CYP2C9 and SLCO1B1 polymorphisms on the pharmacokinetics and pharmacodynamics of nateglinide in healthy Chinese male volunteers
    • 10.1007/s00228-012-1364-9
    • Cheng Y., Wang G., Zhang W., Effect of CYP2C9 and SLCO1B1 polymorphisms on the pharmacokinetics and pharmacodynamics of nateglinide in healthy Chinese male volunteers. European Journal of Clinical Pharmacology 2013 69 3 407 413 10.1007/s00228-012-1364-9
    • (2013) European Journal of Clinical Pharmacology , vol.69 , Issue.3 , pp. 407-413
    • Cheng, Y.1    Wang, G.2    Zhang, W.3
  • 171
    • 78649328506 scopus 로고    scopus 로고
    • Association analysis of SLC30A8 rs13266634 and rs16889462 polymorphisms with type 2 diabetes mellitus and repaglinide response in Chinese patients
    • 2-s2.0-78649328506 10.1007/s00228-010-0882-6
    • Huang Q., Yin J.-Y., Dai X.-P., Wu J., Chen X., Deng C.-S., Yu M., Gong Z.-C., Zhou H.-H., Liu Z.-Q., Association analysis of SLC30A8 rs13266634 and rs16889462 polymorphisms with type 2 diabetes mellitus and repaglinide response in Chinese patients. European Journal of Clinical Pharmacology 2010 66 12 1207 1215 2-s2.0-78649328506 10.1007/s00228-010-0882-6
    • (2010) European Journal of Clinical Pharmacology , vol.66 , Issue.12 , pp. 1207-1215
    • Huang, Q.1    Yin, J.-Y.2    Dai, X.-P.3    Wu, J.4    Chen, X.5    Deng, C.-S.6    Yu, M.7    Gong, Z.-C.8    Zhou, H.-H.9    Liu, Z.-Q.10
  • 172
    • 84862803165 scopus 로고    scopus 로고
    • The influence of MDR1 G2677T/A genetic polymorphisms on the pharmacokinetics of repaglinide in healthy Chinese volunteers
    • 2-s2.0-84857712798 10.1159/000336345
    • Xiang Q., Cui Y. M., Zhao X., Yan L., Zhou Y., The influence of MDR1 G2677T/A genetic polymorphisms on the pharmacokinetics of repaglinide in healthy Chinese volunteers. Pharmacology 2012 89 1-2 105 110 2-s2.0-84857712798 10.1159/000336345
    • (2012) Pharmacology , vol.89 , Issue.1-2 , pp. 105-110
    • Xiang, Q.1    Cui, Y.M.2    Zhao, X.3    Yan, L.4    Zhou, Y.5
  • 173
    • 84860234285 scopus 로고    scopus 로고
    • KCNQ1 gene polymorphisms are associated with the therapeutic efficacy of repaglinide in Chinese type 2 diabetic patients
    • 2-s2.0-84860234285 10.1111/j.1440-1681.2012.05701.x
    • Dai X.-P., Huang Q., Yin J.-Y., Guo Y., Gong Z.-C., Lei M.-X., Jiang T.-J., Zhou H.-H., Liu Z.-Q., KCNQ1 gene polymorphisms are associated with the therapeutic efficacy of repaglinide in Chinese type 2 diabetic patients. Clinical and Experimental Pharmacology and Physiology 2012 39 5 462 468 2-s2.0-84860234285 10.1111/j.1440-1681.2012.05701.x
    • (2012) Clinical and Experimental Pharmacology and Physiology , vol.39 , Issue.5 , pp. 462-468
    • Dai, X.-P.1    Huang, Q.2    Yin, J.-Y.3    Guo, Y.4    Gong, Z.-C.5    Lei, M.-X.6    Jiang, T.-J.7    Zhou, H.-H.8    Liu, Z.-Q.9
  • 175
    • 80455129101 scopus 로고    scopus 로고
    • Genetic polymorphisms of SLCO1B1 for drug pharmacokinetics and its clinical implications
    • 2-s2.0-80455129101 10.1248/yakushi.131.1589
    • Takane H., Genetic polymorphisms of SLCO1B1 for drug pharmacokinetics and its clinical implications. Yakugaku Zasshi 2011 131 11 1589 1594 2-s2.0-80455129101 10.1248/yakushi.131.1589
    • (2011) Yakugaku Zasshi , vol.131 , Issue.11 , pp. 1589-1594
    • Takane, H.1
  • 176
    • 79959753093 scopus 로고    scopus 로고
    • Effects of SLCO1B1 polymorphisms on the pharmacokinetics and pharmacodynamics of repaglinide in healthy Chinese volunteers
    • 2-s2.0-79959753093 10.1007/s00228-011-0994-7
    • He J., Qiu Z., Li N., Yu Y., Lu Y., Han D., Li T., Zhao D., Sun W., Fang F., Zheng J., Fan H., Chen X., Effects of SLCO1B1 polymorphisms on the pharmacokinetics and pharmacodynamics of repaglinide in healthy Chinese volunteers. European Journal of Clinical Pharmacology 2011 67 7 701 707 2-s2.0-79959753093 10.1007/s00228-011-0994-7
    • (2011) European Journal of Clinical Pharmacology , vol.67 , Issue.7 , pp. 701-707
    • He, J.1    Qiu, Z.2    Li, N.3    Yu, Y.4    Lu, Y.5    Han, D.6    Li, T.7    Zhao, D.8    Sun, W.9    Fang, F.10    Zheng, J.11    Fan, H.12    Chen, X.13
  • 177
    • 0036959197 scopus 로고    scopus 로고
    • Pioglitazone: Cardiovascular effects in prediabetic patients
    • 2-s2.0-0036959197
    • Mizushige K., Tsuji T., Noma T., Pioglitazone: cardiovascular effects in prediabetic patients. Cardiovascular Drug Reviews 2002 20 4 329 340 2-s2.0-0036959197
    • (2002) Cardiovascular Drug Reviews , vol.20 , Issue.4 , pp. 329-340
    • Mizushige, K.1    Tsuji, T.2    Noma, T.3
  • 178
    • 23444457610 scopus 로고    scopus 로고
    • Effects of Pro12Ala polymorphism of peroxisome proliferator-activated receptor γ 2 gene on rosiglitazone response in type 2 diabetes
    • 2-s2.0-23444457610 10.1016/j.clpt.2005.04.013
    • Kang E. S., Park S. Y., Kim H. J., Chul S. K., Chul W. A., Bong S. C., Sung K. L., Chung M. N., Hyun C. L., Effects of Pro12Ala polymorphism of peroxisome proliferator-activated receptor γ 2 gene on rosiglitazone response in type 2 diabetes. Clinical Pharmacology & Therapeutics 2005 78 2 202 208 2-s2.0-23444457610 10.1016/j.clpt.2005.04.013
    • (2005) Clinical Pharmacology & Therapeutics , vol.78 , Issue.2 , pp. 202-208
    • Kang, E.S.1    Park, S.Y.2    Kim, H.J.3    Chul, S.K.4    Chul, W.A.5    Bong, S.C.6    Sung, K.L.7    Chung, M.N.8    Hyun, C.L.9
  • 179
    • 78650571748 scopus 로고    scopus 로고
    • Effects of the peroxisome proliferator activated receptor- γ coactivator-1 α (PGC -1 α) Thr394Thr and Gly482Ser polymorphisms on rosiglitazone response in Chinese patients with type 2 diabetes mellitus
    • 2-s2.0-78650571748 10.1177/0091270009355159
    • Zhang K.-H., Huang Q., Dai X.-P., Yin J.-Y., Zhang W., Zhou G., Zhou H.-H., Liu Z.-Q., Effects of the peroxisome proliferator activated receptor- γ coactivator-1 α (PGC -1 α) Thr394Thr and Gly482Ser polymorphisms on rosiglitazone response in Chinese patients with type 2 diabetes mellitus. The Journal of Clinical Pharmacology 2010 50 9 1022 1030 2-s2.0-78650571748 10.1177/0091270009355159
    • (2010) The Journal of Clinical Pharmacology , vol.50 , Issue.9 , pp. 1022-1030
    • Zhang, K.-H.1    Huang, Q.2    Dai, X.-P.3    Yin, J.-Y.4    Zhang, W.5    Zhou, G.6    Zhou, H.-H.7    Liu, Z.-Q.8
  • 180
    • 74749093514 scopus 로고    scopus 로고
    • A pilot study suggests that the G/G genotype of resistin single nucleotide polymorphism at -420 may be an independent predictor of a reduction in fasting plasma glucose and insulin resistance by pioglitazone in type 2 diabetes
    • 2-s2.0-74749093514 10.1507/endocrj.K08E-320
    • Makino H., Shimizu I., Murao S., Kondo S., Tabara Y., Fujiyama M., Fujii Y., Takada Y., Nakai K., Izumi K., Ohashi J., Kawamura R., Yamauchi J., Takata Y., Nishida W., Hashiramoto M., Onuma H., Osawa H., A pilot study suggests that the G/G genotype of resistin single nucleotide polymorphism at -420 may be an independent predictor of a reduction in fasting plasma glucose and insulin resistance by pioglitazone in type 2 diabetes. Endocrine Journal 2009 56 9 1049 1058 2-s2.0-74749093514 10.1507/endocrj.K08E-320
    • (2009) Endocrine Journal , vol.56 , Issue.9 , pp. 1049-1058
    • Makino, H.1    Shimizu, I.2    Murao, S.3    Kondo, S.4    Tabara, Y.5    Fujiyama, M.6    Fujii, Y.7    Takada, Y.8    Nakai, K.9    Izumi, K.10    Ohashi, J.11    Kawamura, R.12    Yamauchi, J.13    Takata, Y.14    Nishida, W.15    Hashiramoto, M.16    Onuma, H.17    Osawa, H.18
  • 181
    • 43549096615 scopus 로고    scopus 로고
    • The association of adiponectin allele 45T/G and - 11377C/G polymorphisms with type 2 diabetes and rosiglitazone response in Chinese patients
    • 2-s2.0-43549096615 10.1111/j.1365-2125.2008.03145.x
    • Sun H., Gong Z.-C., Yin J.-Y., Liu H.-L., Liu Y.-Z., Guo Z.-W., Zhou H.-H., Wu J., Liu Z.-Q., The association of adiponectin allele 45T/G and-11377C/G polymorphisms with type 2 diabetes and rosiglitazone response in Chinese patients. British Journal of Clinical Pharmacology 2008 65 6 917 926 2-s2.0-43549096615 10.1111/j.1365-2125.2008.03145.x
    • (2008) British Journal of Clinical Pharmacology , vol.65 , Issue.6 , pp. 917-926
    • Sun, H.1    Gong, Z.-C.2    Yin, J.-Y.3    Liu, H.-L.4    Liu, Y.-Z.5    Guo, Z.-W.6    Zhou, H.-H.7    Wu, J.8    Liu, Z.-Q.9
  • 182


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