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Volumn 54, Issue 10, 2005, Pages 2844-2851

Attenuated Wnt signaling perturbs pancreatic growth but not pancreatic function

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; FIBROBLAST GROWTH FACTOR 10; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FRIZZLED PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; TRANSCRIPTION FACTOR PDX 1; WNT PROTEIN; WNT1 PROTEIN;

EID: 25844530871     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.54.10.2844     Document Type: Article
Times cited : (132)

References (47)
  • 1
    • 0036301577 scopus 로고    scopus 로고
    • Pancreatic organogenesis-developmental mechanisms and implications for therapy
    • Edlund H: Pancreatic organogenesis-developmental mechanisms and implications for therapy. Nat Rev Genet 3:524-532, 2002
    • (2002) Nat Rev Genet , vol.3 , pp. 524-532
    • Edlund, H.1
  • 2
    • 0033155718 scopus 로고    scopus 로고
    • FGF-FGFR signaling in vertebrate organogenesis
    • Kato S, Sekine K: FGF-FGFR signaling in vertebrate organogenesis. Cell Mol Biol (Noisy-le-grand) 45:631-638, 1999
    • (1999) Cell Mol Biol (Noisy-le-grand) , vol.45 , pp. 631-638
    • Kato, S.1    Sekine, K.2
  • 3
    • 0031661435 scopus 로고    scopus 로고
    • Fibroblast growth factors as multifunctional signaling factors
    • Szebenyi G, Fallon JF: Fibroblast growth factors as multifunctional signaling factors. Int Rev Cytol 185:45-106, 1999
    • (1999) Int Rev Cytol , vol.185 , pp. 45-106
    • Szebenyi, G.1    Fallon, J.F.2
  • 4
    • 0031854251 scopus 로고    scopus 로고
    • Fibroblast growth factor 2 promotes pancreatic epithelial cell proliferation via functional fibroblast growth factor receptors during embryonic life
    • Le Bras S, Miralles F, Basmaciogullari A, Chernichow P, Scharfmann R: Fibroblast growth factor 2 promotes pancreatic epithelial cell proliferation via functional fibroblast growth factor receptors during embryonic life. Diabetes 47:1236-1242, 1998
    • (1998) Diabetes , vol.47 , pp. 1236-1242
    • Le Bras, S.1    Miralles, F.2    Basmaciogullari, A.3    Chernichow, P.4    Scharfmann, R.5
  • 5
    • 0035694459 scopus 로고    scopus 로고
    • Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis
    • Bhushan A, Itoh N, Kato S, Thiery JP, Czernichow P, Bellusci S, Scharfmann R: Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis. Development 128:5109-5117, 2001
    • (2001) Development , vol.128 , pp. 5109-5117
    • Bhushan, A.1    Itoh, N.2    Kato, S.3    Thiery, J.P.4    Czernichow, P.5    Bellusci, S.6    Scharfmann, R.7
  • 6
    • 0141593480 scopus 로고    scopus 로고
    • Fgf10 maintains notch activation, stimulates proliferation, and blocks differentiation of pancreatic epithelial cells
    • Hart AW, Papadopoulou S, Edlund H: Fgf10 maintains notch activation, stimulates proliferation, and blocks differentiation of pancreatic epithelial cells. Dev Dyn 228:185-193, 2003
    • (2003) Dev Dyn , vol.228 , pp. 185-193
    • Hart, A.W.1    Papadopoulou, S.2    Edlund, H.3
  • 7
    • 0344063697 scopus 로고    scopus 로고
    • FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ development
    • Norggard GA, Nyggard Jensen J, Jensen J: FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ development. Dev Biol 264:322-338, 2003
    • (2003) Dev Biol , vol.264 , pp. 322-338
    • Norggard, G.A.1    Nyggard Jensen, J.2    Jensen, J.3
  • 8
    • 0026772731 scopus 로고
    • Wnt genes
    • Nusse R, Varmus HE: Wnt genes. Cell 69:1073-1078, 1992
    • (1992) Cell , vol.69 , pp. 1073-1078
    • Nusse, R.1    Varmus, H.E.2
  • 10
  • 11
    • 0034053069 scopus 로고    scopus 로고
    • Wnt signaling in oncogenesis and embryogenesis: A look outside the nucleus
    • Peifer M, Polakis P: Wnt signaling in oncogenesis and embryogenesis: a look outside the nucleus. Science 287:1606-1609, 2000
    • (2000) Science , vol.287 , pp. 1606-1609
    • Peifer, M.1    Polakis, P.2
  • 12
    • 0032729458 scopus 로고    scopus 로고
    • Signaling through beta-catenin and Lef/Tcf
    • Novak A, Dedhar S: Signaling through beta-catenin and Lef/Tcf. Cell Mol Life Sci 56:523-537, 1999
    • (1999) Cell Mol Life Sci , vol.56 , pp. 523-537
    • Novak, A.1    Dedhar, S.2
  • 14
    • 0037829660 scopus 로고    scopus 로고
    • Canonical Wnt signals are essential for homeostasis of the intestinal epithelium
    • Pinto D, Gregorieff A, Begthel H, Clevers H: Canonical Wnt signals are essential for homeostasis of the intestinal epithelium. Genes Dev 17:1709-1713, 2003
    • (2003) Genes Dev , vol.17 , pp. 1709-1713
    • Pinto, D.1    Gregorieff, A.2    Begthel, H.3    Clevers, H.4
  • 15
    • 0344413420 scopus 로고    scopus 로고
    • Live and let die in the intestinal epithelium
    • Sancho E, Battle E, Clevers H: Live and let die in the intestinal epithelium. Curr Opin Cell Biol 15:763-770, 2003
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 763-770
    • Sancho, E.1    Battle, E.2    Clevers, H.3
  • 16
    • 0036236572 scopus 로고    scopus 로고
    • WNT signaling and lymphocyte development
    • van de Wetering M, de Lau W, Clevers H: WNT signaling and lymphocyte development. Cell 109 (Suppl.):S13-S19, 2002
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Van De Wetering, M.1    De Lau, W.2    Clevers, H.3
  • 18
    • 0036842027 scopus 로고    scopus 로고
    • Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation
    • Heller RS, Dichmann DS, Jensen J, Miller C, Wong G, Madsen OD, Serup P: Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation. Dev Dyn 225:260-270, 2002
    • (2002) Dev Dyn , vol.225 , pp. 260-270
    • Heller, R.S.1    Dichmann, D.S.2    Jensen, J.3    Miller, C.4    Wong, G.5    Madsen, O.D.6    Serup, P.7
  • 21
    • 0033616573 scopus 로고    scopus 로고
    • Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein
    • Hsieh JC, Rattner A, Smallwood PM, Nathans J: Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein. Proc Natl Acad Sci U S A 96:3546-3551, 1999
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 3546-3551
    • Hsieh, J.C.1    Rattner, A.2    Smallwood, P.M.3    Nathans, J.4
  • 24
    • 0031260579 scopus 로고    scopus 로고
    • Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas
    • Apelqvist A, Ahlgren U, Edlund H: Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas. Curr Biol 7:801-804, 1997
    • (1997) Curr Biol , vol.7 , pp. 801-804
    • Apelqvist, A.1    Ahlgren, U.2    Edlund, H.3
  • 25
    • 0034649608 scopus 로고    scopus 로고
    • Attenuation of FGF signalling in mouse beta-cells leads to diabetes
    • Hart AW, Baeza N, Apelqvist A, Edlund H: Attenuation of FGF signalling in mouse beta-cells leads to diabetes. Nature 408:864-868, 2000
    • (2000) Nature , vol.408 , pp. 864-868
    • Hart, A.W.1    Baeza, N.2    Apelqvist, A.3    Edlund, H.4
  • 26
    • 0026335927 scopus 로고
    • The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat
    • Thor S, Ericson J, Brannstrom T, Edlund T: The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat. Neuron 7:881-889, 1991
    • (1991) Neuron , vol.7 , pp. 881-889
    • Thor, S.1    Ericson, J.2    Brannstrom, T.3    Edlund, T.4
  • 27
    • 0035584535 scopus 로고    scopus 로고
    • Persistent expression of Hlxb9 in the pancreatic epithelium impairs pancreatic development
    • Li H, Edlund H: Persistent expression of Hlxb9 in the pancreatic epithelium impairs pancreatic development. Dev Biol 240:247-253, 2001
    • (2001) Dev Biol , vol.240 , pp. 247-253
    • Li, H.1    Edlund, H.2
  • 28
    • 12144279068 scopus 로고    scopus 로고
    • Nuclear factor-(kappa)B activity in (beta)-cells is required for glucose-stimulated insulin secretion
    • Norlin S, Ahlgren U, Edlund H: Nuclear factor-(kappa)B activity in (beta)-cells is required for glucose-stimulated insulin secretion. Diabetes 54:125-132, 2005
    • (2005) Diabetes , vol.54 , pp. 125-132
    • Norlin, S.1    Ahlgren, U.2    Edlund, H.3
  • 29
    • 0036802645 scopus 로고    scopus 로고
    • WntTb regulates mesenchymal proliferation and vascular development in the lung
    • Shu W, Jiang YQ, Lu MM, Morrisey EE: WntTb regulates mesenchymal proliferation and vascular development in the lung. Development 129: 4831-4842, 2002
    • (2002) Development , vol.129 , pp. 4831-4842
    • Shu, W.1    Jiang, Y.Q.2    Lu, M.M.3    Morrisey, E.E.4
  • 33
    • 4544308625 scopus 로고    scopus 로고
    • Beta-catenin signaling marks the prospective site of primitive streak formation in the mouse embryo
    • Mohamed OA, Clarke HJ, Dufort D: Beta-catenin signaling marks the prospective site of primitive streak formation in the mouse embryo. Dev Dyn 231:416-424, 2004
    • (2004) Dev Dyn , vol.231 , pp. 416-424
    • Mohamed, O.A.1    Clarke, H.J.2    Dufort, D.3
  • 34
    • 0032525981 scopus 로고    scopus 로고
    • Beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes
    • Ahlgren U, Jonsson J, Jonsson L, Simu K, Edlund H: beta-Cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes. Genes Dev 12:1763-1768, 1998
    • (1998) Genes Dev , vol.12 , pp. 1763-1768
    • Ahlgren, U.1    Jonsson, J.2    Jonsson, L.3    Simu, K.4    Edlund, H.5
  • 35
    • 0032957137 scopus 로고    scopus 로고
    • The specification of dorsal cell fates in the vertebrate central nervous system
    • Lee KJ, Jessell TM: The specification of dorsal cell fates in the vertebrate central nervous system. Annu Rev Neurosci 22:261-294, 1999
    • (1999) Annu Rev Neurosci , vol.22 , pp. 261-294
    • Lee, K.J.1    Jessell, T.M.2
  • 36
    • 0033998420 scopus 로고    scopus 로고
    • Reiterative signaling and patterning during mammalian tooth morphogenesis
    • Jernvall J, Thesleff I: Reiterative signaling and patterning during mammalian tooth morphogenesis. Mech Dev 92:19-29, 2000
    • (2000) Mech Dev , vol.92 , pp. 19-29
    • Jernvall, J.1    Thesleff, I.2
  • 37
    • 1342344014 scopus 로고    scopus 로고
    • Tomorrow's skeleton staff: Mesenchymal stem cells and the repair of bone and cartilage
    • Otto WR, Rao J: Tomorrow's skeleton staff: mesenchymal stem cells and the repair of bone and cartilage. Cell Prolif 37:97-110, 2004
    • (2004) Cell Prolif , vol.37 , pp. 97-110
    • Otto, W.R.1    Rao, J.2
  • 38
    • 0028149890 scopus 로고
    • Insulin-promoter-factor 1 is required for pancreas development in mice
    • Jonsson J, Carlsson L, Edlund T, Edlund H: Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371:606-609, 1994
    • (1994) Nature , vol.371 , pp. 606-609
    • Jonsson, J.1    Carlsson, L.2    Edlund, T.3    Edlund, H.4
  • 40
    • 0027384997 scopus 로고
    • IPF1, a homeodomain-containing transactivator of the insulin gene
    • Ohlsson H, Karlsson K, Edlund T: IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J 12:4251-4259, 1993
    • (1993) EMBO J , vol.12 , pp. 4251-4259
    • Ohlsson, H.1    Karlsson, K.2    Edlund, T.3
  • 41
    • 0035122488 scopus 로고    scopus 로고
    • Endocrine pancreas plasticity under physiological and pathological conditions
    • Bernard-Kargar C, Ktorza A: Endocrine pancreas plasticity under physiological and pathological conditions. Diabetes 50 (Suppl. 1):S30-S35, 2001
    • (2001) Diabetes , vol.50 , Issue.SUPPL. 1
    • Bernard-Kargar, C.1    Ktorza, A.2
  • 42
    • 0023936007 scopus 로고
    • Morphological evidence for pancreatic polarity of beta-cell within islets of Langerhans
    • Bonner-Weir S: Morphological evidence for pancreatic polarity of beta-cell within islets of Langerhans. Diabetes 37:616-621, 1988
    • (1988) Diabetes , vol.37 , pp. 616-621
    • Bonner-Weir, S.1
  • 43
    • 0023940801 scopus 로고
    • Minimal chronic hyperglycemia is a critical determinant of impaired insulin secretion after an incomplete pancreatectomy
    • Leahy JL, Bonner-Weir S, Weir GC: Minimal chronic hyperglycemia is a critical determinant of impaired insulin secretion after an incomplete pancreatectomy. J Clin Invest 81:1407-1414, 1988
    • (1988) J Clin Invest , vol.81 , pp. 1407-1414
    • Leahy, J.L.1    Bonner-Weir, S.2    Weir, G.C.3
  • 45
    • 0030961962 scopus 로고    scopus 로고
    • Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes: Genetic reconstitution of diabetes as a polygenic disease
    • Terauchi Y, Iwamoto K, Tamemoto H, Komeda K, Ishii C, Kanazawa Y, Asanuma N, Aizawa T, Akanuma Y, Yasuda K, Kodama T, Tobe K, Yazaki Y, Kadowaki T: Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes: genetic reconstitution of diabetes as a polygenic disease. J Clin Invest 99:861-866, 1997
    • (1997) J Clin Invest , vol.99 , pp. 861-866
    • Terauchi, Y.1    Iwamoto, K.2    Tamemoto, H.3    Komeda, K.4    Ishii, C.5    Kanazawa, Y.6    Asanuma, N.7    Aizawa, T.8    Akanuma, Y.9    Yasuda, K.10    Kodama, T.11    Tobe, K.12    Yazaki, Y.13    Kadowaki, T.14
  • 47
    • 12144272235 scopus 로고    scopus 로고
    • Reduction of beta cell mass: Partial insulin secretory compensation from the residual beta cell population in the nicotinamide-streptozotocin Gottingen minipig after oral glucose in vivo and in the perfused pancreas
    • Larsen MO, Rolin B, Gotfredsen CF, Carr RD, Holst JJ: Reduction of beta cell mass: partial insulin secretory compensation from the residual beta cell population in the nicotinamide-streptozotocin Gottingen minipig after oral glucose in vivo and in the perfused pancreas. Diabetologia 47:1873-1878, 2004
    • (2004) Diabetologia , vol.47 , pp. 1873-1878
    • Larsen, M.O.1    Rolin, B.2    Gotfredsen, C.F.3    Carr, R.D.4    Holst, J.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.