Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with decreased β-cell function whereas risk alleles near ANKRD55 and GRB14 associate with decreased insulin sensitivity in the danish Inter99 cohort

Journal of Clinical Endocrinology and Metabolism

Volumn 98, Issue 4, 2013, Pages

  Harder, Marie N ^a   Ribel Madsen, Rasmus ^a   Justesen, Johanne M ^a   Sparsø, Thomas ^a   Andersson, Ehm A ^a   Grarup, Niels ^a   Jørgensen, Torben ^b,d   Linneberg, Allan ^d   Hansen, Torben ^a,e   Pedersen, Oluf ^a,c,f  

^a Capital Region   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d GLOSTRUP UNIVERSITY HOSPITAL   (Denmark)

^e UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^f AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN;

ADULT; ALLELE; ANK1 GENE; ANKRD55 GENE; ARTICLE; BCAR1 GENE; CASE CONTROL STUDY; CELL FUNCTION; CILP2 GENE; COHORT ANALYSIS; CONTROLLED STUDY; DANISH; DIABETOGENESIS; DISEASE PREDISPOSITION; ETHNIC GROUP; FEMALE; GENE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GLUCOSE BLOOD LEVEL; GRB14 GENE; HMG20A GENE; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; KLHDC5 GENE; MAJOR CLINICAL STUDY; MALE; MC4R GENE; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; QUANTITATIVE TRAIT; RATING SCALE; SINGLE NUCLEOTIDE POLYMORPHISM; WAIST CIRCUMFERENCE; ZMIZ1 GENE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; ALLELES; ANKYRINS; CASE-CONTROL STUDIES; COHORT STUDIES; CRK-ASSOCIATED SUBSTRATE PROTEIN; DENMARK; DIABETES MELLITUS, TYPE 2; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INSULIN; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PREDIABETIC STATE; QUANTITATIVE TRAIT LOCI; RISK FACTORS;

EID: 84876219189     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2012-4169     Document Type: Article

References (13)

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