-
1
-
-
0035856920
-
Global and societal implications of the diabetes epidemic
-
Zimmet P, Alberti KG, Shaw J (2001) Global and societal implications of the diabetes epidemic. Nature 414: 782-787.
-
(2001)
Nature
, vol.414
, pp. 782-787
-
-
Zimmet, P.1
Alberti, K.G.2
Shaw, J.3
-
2
-
-
17044386953
-
Type 2 diabetes: Principles of pathogenesis and therapy
-
Stumvoll M, Goldstein BJ, van Haeften TW (2005) Type 2 diabetes: principles of pathogenesis and therapy. Lancet 365: 1333-1346.
-
(2005)
Lancet
, vol.365
, pp. 1333-1346
-
-
Stumvoll, M.1
Goldstein, B.J.2
van Haeften, T.W.3
-
3
-
-
0028845529
-
Maturity-onset diabetes of the young (MODY) at least ten times more common in Europe than previously assumed?
-
Ledermann HM (1995) Maturity-onset diabetes of the young (MODY) at least ten times more common in Europe than previously assumed? Diabetologia 38: 1482.
-
(1995)
Diabetologia
, vol.38
, pp. 1482
-
-
Ledermann, H.M.1
-
4
-
-
0842285626
-
Mitochondrial diabetes: Molecular mechanisms and clinical presentation
-
Maassen JA, LM TH, Van Essen E, Heine RJ, Nijpels G, et al. (2004) Mitochondrial diabetes: molecular mechanisms and clinical presentation. Diabetes 53 Suppl 1: S103-109.
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 1
-
-
Maassen, J.A.1
LM, T.H.2
Van Essen, E.3
Heine, R.J.4
Nijpels, G.5
-
5
-
-
0035960122
-
Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young
-
Fajans SS, Bell GI, Polonsky KS (2001) Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young. N Engl J Med 345: 971-980.
-
(2001)
N Engl J Med
, vol.345
, pp. 971-980
-
-
Fajans, S.S.1
Bell, G.I.2
Polonsky, K.S.3
-
6
-
-
39649114799
-
Genetic susceptibility to type 2 diabetes and implications for antidiabetic therapy
-
Moore AF, Florez JC (2008) Genetic susceptibility to type 2 diabetes and implications for antidiabetic therapy. Annu Rev Med 59: 95-111.
-
(2008)
Annu Rev Med
, vol.59
, pp. 95-111
-
-
Moore, A.F.1
Florez, J.C.2
-
7
-
-
12144288056
-
Linkage of the metabolic syndrome to 1q23-q31 in Hispanic families: The Insulin Resistance Atherosclerosis Study Family Study
-
Langefeld CD, Wagenknecht LE, Rotter JI, Williams AH, Hokanson JE, et al. (2004) Linkage of the metabolic syndrome to 1q23-q31 in Hispanic families: the Insulin Resistance Atherosclerosis Study Family Study. Diabetes 53: 1170-1174.
-
(2004)
Diabetes
, vol.53
, pp. 1170-1174
-
-
Langefeld, C.D.1
Wagenknecht, L.E.2
Rotter, J.I.3
Williams, A.H.4
Hokanson, J.E.5
-
8
-
-
0032231322
-
An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians
-
Hanson RL, Ehm MG, Pettitt DJ, Prochazka M, Thompson DB, et al. (1998) An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians. Am J Hum Genet 63: 1130-1138.
-
(1998)
Am J Hum Genet
, vol.63
, pp. 1130-1138
-
-
Hanson, R.L.1
Ehm, M.G.2
Pettitt, D.J.3
Prochazka, M.4
Thompson, D.B.5
-
9
-
-
0032910599
-
A genome-wide search for type 2 diabetes susceptibility genes in Utah Caucasians
-
Elbein SC, Hoffman MD, Teng K, Leppert MF, Hasstedt SJ (1999) A genome-wide search for type 2 diabetes susceptibility genes in Utah Caucasians. Diabetes 48: 1175-1182.
-
(1999)
Diabetes
, vol.48
, pp. 1175-1182
-
-
Elbein, S.C.1
Hoffman, M.D.2
Teng, K.3
Leppert, M.F.4
Hasstedt, S.J.5
-
10
-
-
0033652271
-
Genomewide search for type 2 diabetes-susceptibility genes in French whites: Evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24
-
Vionnet N, Hani EH, Dupont S, Gallina S, Francke S, et al. (2000) Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24. Am J Hum Genet 67: 1470-1480.
-
(2000)
Am J Hum Genet
, vol.67
, pp. 1470-1480
-
-
Vionnet, N.1
Hani, E.H.2
Dupont, S.3
Gallina, S.4
Francke, S.5
-
11
-
-
0037302950
-
Genomic scan of glucose and insulin metabolism phenotypes: The HERITAGE Family Study
-
An P, Hong Y, Weisnagel SJ, Rice T, Rankinen T, et al. (2003) Genomic scan of glucose and insulin metabolism phenotypes: the HERITAGE Family Study. Metabolism 52: 246-253.
-
(2003)
Metabolism
, vol.52
, pp. 246-253
-
-
An, P.1
Hong, Y.2
Weisnagel, S.J.3
Rice, T.4
Rankinen, T.5
-
12
-
-
0034893106
-
A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): Analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q
-
Wiltshire S, Hattersley AT, Hitman GA,WalkerM, Levy JC, et al. (2001) A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q. Am J Hum Genet 69: 553-569.
-
(2001)
Am J Hum Genet
, vol.69
, pp. 553-569
-
-
Wiltshire, S.1
Hattersley, A.T.2
Hitman, G.A.3
Walker, M.4
Levy, J.C.5
-
13
-
-
0037312885
-
Genome-wide and fine-mapping linkage studies of type 2 diabetes and glucose traits in the Old Order Amish: Evidence for a new diabetes locus on chromosome 14q11 and confirmation of a locus on chromosome 1q21-q24
-
Hsueh WC, St Jean PL, Mitchell BD, Pollin TI, Knowler WC, et al. (2003) Genome-wide and fine-mapping linkage studies of type 2 diabetes and glucose traits in the Old Order Amish: evidence for a new diabetes locus on chromosome 14q11 and confirmation of a locus on chromosome 1q21-q24. Diabetes 52: 550-557.
-
(2003)
Diabetes
, vol.52
, pp. 550-557
-
-
Hsueh, W.C.1
St Jean, P.L.2
Mitchell, B.D.3
Pollin, T.I.4
Knowler, W.C.5
-
14
-
-
0030897631
-
Linkage of genetic markers on human chromosomes 20 and 12 to NIDDM in Caucasian sib pairs with a history of diabetic nephropathy
-
Bowden DW, Sale M, Howard TD, Qadri A, Spray BJ, et al. (1997) Linkage of genetic markers on human chromosomes 20 and 12 to NIDDM in Caucasian sib pairs with a history of diabetic nephropathy. Diabetes 46: 882-886.
-
(1997)
Diabetes
, vol.46
, pp. 882-886
-
-
Bowden, D.W.1
Sale, M.2
Howard, T.D.3
Qadri, A.4
Spray, B.J.5
-
15
-
-
9144243533
-
Genome-wide search for type 2 diabetes/impaired glucose homeostasis susceptibility genes in the Chinese: Significant linkage to chromosome 6q21-q23 and chromosome 1q21-q24
-
Xiang K, Wang Y, Zheng T, Jia W, Li J, et al. (2004) Genome-wide search for type 2 diabetes/impaired glucose homeostasis susceptibility genes in the Chinese: significant linkage to chromosome 6q21-q23 and chromosome 1q21-q24. Diabetes 53: 228-234.
-
(2004)
Diabetes
, vol.53
, pp. 228-234
-
-
Xiang, K.1
Wang, Y.2
Zheng, T.3
Jia, W.4
Li, J.5
-
16
-
-
0030907295
-
New susceptibility locus for NIDDM is localized to human chromosome 20q
-
Ji L, Malecki M, Warram JH, Yang Y, Rich SS, et al. (1997) New susceptibility locus for NIDDM is localized to human chromosome 20q. Diabetes 46: 876-881.
-
(1997)
Diabetes
, vol.46
, pp. 876-881
-
-
Ji, L.1
Malecki, M.2
Warram, J.H.3
Yang, Y.4
Rich, S.S.5
-
17
-
-
0030766446
-
A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene
-
Zouali H, Hani EH, Philippi A, Vionnet N, Beckmann JS, et al. (1997) A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene. Hum Mol Genet 6: 1401-1408.
-
(1997)
Hum Mol Genet
, vol.6
, pp. 1401-1408
-
-
Zouali, H.1
Hani, E.H.2
Philippi, A.3
Vionnet, N.4
Beckmann, J.S.5
-
18
-
-
13044277561
-
Type 2 diabetes: Evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs
-
Ghosh S, Watanabe RM, Hauser ER, Valle T, Magnuson VL, et al. (1999) Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs. Proc Natl Acad Sci U S A 96: 2198-2203.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 2198-2203
-
-
Ghosh, S.1
Watanabe, R.M.2
Hauser, E.R.3
Valle, T.4
Magnuson, V.L.5
-
19
-
-
0033658920
-
Further evidence for a susceptibility locus for type 2 diabetes on chromosome 20q13.1-q13.2
-
Klupa T, Malecki MT, Pezzolesi M, Ji L, Curtis S, et al. (2000) Further evidence for a susceptibility locus for type 2 diabetes on chromosome 20q13.1-q13.2. Diabetes 49: 2212-2216.
-
(2000)
Diabetes
, vol.49
, pp. 2212-2216
-
-
Klupa, T.1
Malecki, M.T.2
Pezzolesi, M.3
Ji, L.4
Curtis, S.5
-
20
-
-
0033624575
-
The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
-
Altshuler D, Hirschhorn JN, Klannemark M, Lindgren CM, Vohl MC, et al. (2000) The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 26: 76-80.
-
(2000)
Nat Genet
, vol.26
, pp. 76-80
-
-
Altshuler, D.1
Hirschhorn, J.N.2
Klannemark, M.3
Lindgren, C.M.4
Vohl, M.C.5
-
21
-
-
2342561802
-
Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region
-
Florez JC, Burtt N, de Bakker PI, Almgren P, Tuomi T, et al. (2004) Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region. Diabetes 53: 1360-1368.
-
(2004)
Diabetes
, vol.53
, pp. 1360-1368
-
-
Florez, J.C.1
Burtt, N.2
de Bakker, P.I.3
Almgren, P.4
Tuomi, T.5
-
22
-
-
0037317981
-
Largescale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes
-
Gloyn AL, Weedon MN, Owen KR, Turner MJ, Knight BA, et al. (2003) Largescale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes. Diabetes 52: 568-572.
-
(2003)
Diabetes
, vol.52
, pp. 568-572
-
-
Gloyn, A.L.1
Weedon, M.N.2
Owen, K.R.3
Turner, M.J.4
Knight, B.A.5
-
23
-
-
0037312864
-
The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes
-
Nielsen EM, Hansen L, Carstensen B, Echwald SM, Drivsholm T, et al. (2003) The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes. Diabetes 52: 573-577.
-
(2003)
Diabetes
, vol.52
, pp. 573-577
-
-
Nielsen, E.M.1
Hansen, L.2
Carstensen, B.3
Echwald, S.M.4
Drivsholm, T.5
-
24
-
-
34547510624
-
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes
-
Gudmundsson J, Sulem P, Steinthorsdottir V, Bergthorsson JT, Thorleifsson G, et al. (2007) Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet 39: 977-983.
-
(2007)
Nat Genet
, vol.39
, pp. 977-983
-
-
Gudmundsson, J.1
Sulem, P.2
Steinthorsdottir, V.3
Bergthorsson, J.T.4
Thorleifsson, G.5
-
25
-
-
33847361938
-
Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes
-
Winckler W, Weedon MN, Graham RR, McCarroll SA, Purcell S, et al. (2007) Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes. Diabetes 56: 685-693.
-
(2007)
Diabetes
, vol.56
, pp. 685-693
-
-
Winckler, W.1
Weedon, M.N.2
Graham, R.R.3
McCarroll, S.A.4
Purcell, S.5
-
26
-
-
34547536393
-
Common variants in WFS1 confer risk of type 2 diabetes
-
Sandhu MS, Weedon MN, Fawcett KA, Wasson J, Debenham SL, et al. (2007) Common variants in WFS1 confer risk of type 2 diabetes. Nat Genet 39: 951-953.
-
(2007)
Nat Genet
, vol.39
, pp. 951-953
-
-
Sandhu, M.S.1
Weedon, M.N.2
Fawcett, K.A.3
Wasson, J.4
Debenham, S.L.5
-
27
-
-
34249885875
-
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
-
Scott LJ, Mohlke KL, Bonnycastle LL, Willer CJ, Li Y, et al. (2007) A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 316: 1341-1345.
-
(2007)
Science
, vol.316
, pp. 1341-1345
-
-
Scott, L.J.1
Mohlke, K.L.2
Bonnycastle, L.L.3
Willer, C.J.4
Li, Y.5
-
28
-
-
50449085998
-
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
-
Yasuda K, Miyake K, Horikawa Y, Hara K, Osawa H, et al. (2008) Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nat Genet 40: 1092-1097.
-
(2008)
Nat Genet
, vol.40
, pp. 1092-1097
-
-
Yasuda, K.1
Miyake, K.2
Horikawa, Y.3
Hara, K.4
Osawa, H.5
-
29
-
-
50449085212
-
SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations
-
Unoki H, Takahashi A, Kawaguchi T, Hara K, Horikoshi M, et al. (2008) SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nat Genet 40: 1098-1102.
-
(2008)
Nat Genet
, vol.40
, pp. 1098-1102
-
-
Unoki, H.1
Takahashi, A.2
Kawaguchi, T.3
Hara, K.4
Horikoshi, M.5
-
30
-
-
34249828965
-
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
-
Steinthorsdottir V, Thorleifsson G, Reynisdottir I, Benediktsson R, Jonsdottir T, et al. (2007) A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet 39: 770-775.
-
(2007)
Nat Genet
, vol.39
, pp. 770-775
-
-
Steinthorsdottir, V.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Jonsdottir, T.5
-
31
-
-
84969213492
-
000 cases of seven common diseases and 3,000 shared controls
-
Genome-wide association study of 14
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447: 661-678.
-
Nature
, vol.447
, pp. 661-678
-
-
-
32
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PI, et al. (2007) Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316: 1331-1336.
-
(2007)
Science
, vol.316
, pp. 1331-1336
-
-
Saxena, R.1
Voight, B.F.2
Lyssenko, V.3
Burtt, N.P.4
de Bakker, P.I.5
-
33
-
-
34249895023
-
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
-
Zeggini E, Weedon MN, Lindgren CM, Frayling TM, Elliott KS, et al. (2007) Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 316: 1336-1341.
-
(2007)
Science
, vol.316
, pp. 1336-1341
-
-
Zeggini, E.1
Weedon, M.N.2
Lindgren, C.M.3
Frayling, T.M.4
Elliott, K.S.5
-
34
-
-
42349106044
-
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
-
Zeggini E, Scott LJ, Saxena R, Voight BF, Marchini JL, et al. (2008) Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 40: 638-645.
-
(2008)
Nat Genet
, vol.40
, pp. 638-645
-
-
Zeggini, E.1
Scott, L.J.2
Saxena, R.3
Voight, B.F.4
Marchini, J.L.5
-
35
-
-
58149175143
-
A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk
-
Bouatia-Naji N, Bonnefond A, Cavalcanti-Proenca C, Sparso T, Holmkvist J, et al. (2009) A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk. Nat Genet 41: 89-94.
-
(2009)
Nat Genet
, vol.41
, pp. 89-94
-
-
Bouatia-Naji, N.1
Bonnefond, A.2
Cavalcanti-Proenca, C.3
Sparso, T.4
Holmkvist, J.5
-
36
-
-
58149175669
-
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion
-
Lyssenko V, Nagorny CL, Erdos MR, Wierup N, Jonsson A, et al. (2009) Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion. Nat Genet 41: 82-88.
-
(2009)
Nat Genet
, vol.41
, pp. 82-88
-
-
Lyssenko, V.1
Nagorny, C.L.2
Erdos, M.R.3
Wierup, N.4
Jonsson, A.5
-
37
-
-
58149156287
-
Variants in MTNR1B influence fasting glucose levels
-
Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, et al. (2009) Variants in MTNR1B influence fasting glucose levels. Nat Genet 41: 77-81.
-
(2009)
Nat Genet
, vol.41
, pp. 77-81
-
-
Prokopenko, I.1
Langenberg, C.2
Florez, J.C.3
Saxena, R.4
Soranzo, N.5
-
38
-
-
33847176604
-
A genome-wide association study identifies novel risk loci for type 2 diabetes
-
Sladek R, Rocheleau G, Rung J, Dina C, Shen L, et al. (2007) A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 445: 881-885.
-
(2007)
Nature
, vol.445
, pp. 881-885
-
-
Sladek, R.1
Rocheleau, G.2
Rung, J.3
Dina, C.4
Shen, L.5
-
39
-
-
32544451924
-
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
-
Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, et al. (2006) Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 38: 320-323.
-
(2006)
Nat Genet
, vol.38
, pp. 320-323
-
-
Grant, S.F.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Manolescu, A.5
-
40
-
-
67650248695
-
Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population
-
Takeuchi F, Serizawa M, Yamamoto K, Fujisawa T, Nakashima E, et al. (2009) Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. Diabetes 58: 1690-1699.
-
(2009)
Diabetes
, vol.58
, pp. 1690-1699
-
-
Takeuchi, F.1
Serizawa, M.2
Yamamoto, K.3
Fujisawa, T.4
Nakashima, E.5
-
41
-
-
40949087723
-
Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population
-
Omori S, Tanaka Y, Takahashi A, Hirose H, Kashiwagi A, et al. (2008) Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population. Diabetes 57: 791-795.
-
(2008)
Diabetes
, vol.57
, pp. 791-795
-
-
Omori, S.1
Tanaka, Y.2
Takahashi, A.3
Hirose, H.4
Kashiwagi, A.5
-
42
-
-
67349205597
-
Variations in KCNQ1 are associated with type 2 diabetes and beta cell function in a Chinese population
-
Hu C, Wang C, Zhang R, Ma X, Wang J, et al. (2009) Variations in KCNQ1 are associated with type 2 diabetes and beta cell function in a Chinese population. Diabetologia 52: 1322-1325.
-
(2009)
Diabetologia
, vol.52
, pp. 1322-1325
-
-
Hu, C.1
Wang, C.2
Zhang, R.3
Ma, X.4
Wang, J.5
-
43
-
-
56349170898
-
Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population
-
Wu Y, Li H, Loos RJ, Yu Z, Ye X, et al. (2008) Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population. Diabetes 57: 2834-2842.
-
(2008)
Diabetes
, vol.57
, pp. 2834-2842
-
-
Wu, Y.1
Li, H.2
Loos, R.J.3
Yu, Z.4
Ye, X.5
-
44
-
-
34948845069
-
Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population
-
Chang YC, Chang TJ, Jiang YD, Kuo SS, Lee KC, et al. (2007) Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population. Diabetes 56: 2631-2637.
-
(2007)
Diabetes
, vol.56
, pp. 2631-2637
-
-
Chang, Y.C.1
Chang, T.J.2
Jiang, Y.D.3
Kuo, S.S.4
Lee, K.C.5
-
45
-
-
64149094603
-
A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals
-
Ronn T, Wen J, Yang Z, Lu B, Du Y, et al. (2009) A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals. Diabetologia 52: 830-833.
-
(2009)
Diabetologia
, vol.52
, pp. 830-833
-
-
Ronn, T.1
Wen, J.2
Yang, Z.3
Lu, B.4
Du, Y.5
-
46
-
-
64649086755
-
Common variants of hepatocyte nuclear factor 1beta are associated with type 2 diabetes in a Chinese population
-
Wang C, Hu C, Zhang R, Bao Y, Ma X, et al. (2009) Common variants of hepatocyte nuclear factor 1beta are associated with type 2 diabetes in a Chinese population. Diabetes 58: 1023-1027.
-
(2009)
Diabetes
, vol.58
, pp. 1023-1027
-
-
Wang, C.1
Hu, C.2
Zhang, R.3
Bao, Y.4
Ma, X.5
-
47
-
-
68449086849
-
The E23K variation in the KCNJ11 gene is associated with type 2 diabetes in Chinese and East Asian population
-
Zhou D, Zhang D, Liu Y, Zhao T, Chen Z, et al. (2009) The E23K variation in the KCNJ11 gene is associated with type 2 diabetes in Chinese and East Asian population. J Hum Genet 54: 433-435.
-
(2009)
J Hum Genet
, vol.54
, pp. 433-435
-
-
Zhou, D.1
Zhang, D.2
Liu, Y.3
Zhao, T.4
Chen, Z.5
-
48
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81: 559-575.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.5
-
49
-
-
0031594367
-
Transgenic mice deficient in the LAR protein-tyrosine phosphatase exhibit profound defects in glucose homeostasis
-
Ren JM, Li PM, Zhang WR, Sweet LJ, Cline G, et al. (1998) Transgenic mice deficient in the LAR protein-tyrosine phosphatase exhibit profound defects in glucose homeostasis. Diabetes 47: 493-497.
-
(1998)
Diabetes
, vol.47
, pp. 493-497
-
-
Ren, J.M.1
Li, P.M.2
Zhang, W.R.3
Sweet, L.J.4
Cline, G.5
-
50
-
-
33845423553
-
Altered glucose homeostasis in mice lacking the receptor protein tyrosine phosphatase sigma
-
Chagnon MJ, Elchebly M, Uetani N, Dombrowski L, Cheng A, et al. (2006) Altered glucose homeostasis in mice lacking the receptor protein tyrosine phosphatase sigma. Can J Physiol Pharmacol 84: 755-763.
-
(2006)
Can J Physiol Pharmacol
, vol.84
, pp. 755-763
-
-
Chagnon, M.J.1
Elchebly, M.2
Uetani, N.3
Dombrowski, L.4
Cheng, A.5
-
51
-
-
0036137813
-
Pituitary, pancreatic and gut neuroendocrine defects in protein tyrosine phosphatase-sigma-deficient mice
-
Batt J, Asa S, Fladd C, Rotin D (2002) Pituitary, pancreatic and gut neuroendocrine defects in protein tyrosine phosphatase-sigma-deficient mice. Mol Endocrinol 16: 155-169.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 155-169
-
-
Batt, J.1
Asa, S.2
Fladd, C.3
Rotin, D.4
-
52
-
-
84890417804
-
The genetical structure of populations
-
Wright S (1951) The genetical structure of populations. Annals of Eugenics 15: 323-354.
-
(1951)
Annals of Eugenics
, vol.15
, pp. 323-354
-
-
Wright, S.1
-
53
-
-
0034659955
-
Impaired learning with enhanced hippocampal long-term potentiation in PTPdelta-deficient mice
-
Uetani N, Kato K, Ogura H, Mizuno K, Kawano K, et al. (2000) Impaired learning with enhanced hippocampal long-term potentiation in PTPdelta-deficient mice. Embo J 19: 2775-2785.
-
(2000)
Embo J
, vol.19
, pp. 2775-2785
-
-
Uetani, N.1
Kato, K.2
Ogura, H.3
Mizuno, K.4
Kawano, K.5
-
54
-
-
0029417204
-
The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: Multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1
-
Pulido R, Serra-Pages C, Tang M, Streuli M (1995) The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1. Proc Natl Acad Sci U S A 92: 11686-11690.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 11686-11690
-
-
Pulido, R.1
Serra-Pages, C.2
Tang, M.3
Streuli, M.4
-
55
-
-
26944490279
-
Identification of chromosome arm 9p as the most frequent target of homozygous deletions in lung cancer
-
Sato M, Takahashi K, Nagayama K, Arai Y, Ito N, et al. (2005) Identification of chromosome arm 9p as the most frequent target of homozygous deletions in lung cancer. Genes Chromosomes Cancer 44: 405-414.
-
(2005)
Genes Chromosomes Cancer
, vol.44
, pp. 405-414
-
-
Sato, M.1
Takahashi, K.2
Nagayama, K.3
Arai, Y.4
Ito, N.5
-
56
-
-
16844386333
-
Functional significance of the LAR receptor protein tyrosine phosphatase family in development and diseases
-
Chagnon MJ, Uetani N, Tremblay ML (2004) Functional significance of the LAR receptor protein tyrosine phosphatase family in development and diseases. Biochem Cell Biol 82: 664-675.
-
(2004)
Biochem Cell Biol
, vol.82
, pp. 664-675
-
-
Chagnon, M.J.1
Uetani, N.2
Tremblay, M.L.3
-
57
-
-
0035942161
-
Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance
-
Zabolotny JM, Kim YB, Peroni OD, Kim JK, Pani MA, et al. (2001) Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance. Proc Natl Acad Sci U S A 98: 5187-5192.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 5187-5192
-
-
Zabolotny, J.M.1
Kim, Y.B.2
Peroni, O.D.3
Kim, J.K.4
Pani, M.A.5
-
58
-
-
0033539510
-
Serine racemase: A glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission
-
Wolosker H, Blackshaw S, Snyder SH (1999) Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission. Proc Natl Acad Sci U S A 96: 13409-13414.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 13409-13414
-
-
Wolosker, H.1
Blackshaw, S.2
Snyder, S.H.3
-
59
-
-
0033582230
-
Purification of serine racemase: Biosynthesis of the neuromodulator D-serine
-
Wolosker H, Sheth KN, Takahashi M, Mothet JP, Brady RO Jr, et al. (1999) Purification of serine racemase: biosynthesis of the neuromodulator D-serine. Proc Natl Acad Sci U S A 96: 721-725.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 721-725
-
-
Wolosker, H.1
Sheth, K.N.2
Takahashi, M.3
Mothet, J.P.4
Brady Jr, R.O.5
-
60
-
-
0037195093
-
Cofactors of serine racemase that physiologically stimulate the synthesis of the N-methyl-Daspartate (NMDA) receptor coagonist D-serine
-
De Miranda J, Panizzutti R, Foltyn VN, Wolosker H (2002) Cofactors of serine racemase that physiologically stimulate the synthesis of the N-methyl-Daspartate (NMDA) receptor coagonist D-serine. Proc Natl Acad Sci U S A 99: 14542-14547.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 14542-14547
-
-
De Miranda, J.1
Panizzutti, R.2
Foltyn, V.N.3
Wolosker, H.4
-
61
-
-
0034712857
-
Dserine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor
-
Mothet JP, Parent AT, Wolosker H, Brady RO Jr, Linden DJ, et al. (2000) Dserine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. Proc Natl Acad Sci U S A 97: 4926-4931.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 4926-4931
-
-
Mothet, J.P.1
Parent, A.T.2
Wolosker, H.3
Brady Jr, R.O.4
Linden, D.J.5
-
62
-
-
50549099422
-
D-amino acids in the brain: D-serine in neurotransmission and neurodegeneration
-
Wolosker H, Dumin E, Balan L, Foltyn VN (2008) D-amino acids in the brain: D-serine in neurotransmission and neurodegeneration. Febs J 275: 3514-3526.
-
(2008)
Febs J
, vol.275
, pp. 3514-3526
-
-
Wolosker, H.1
Dumin, E.2
Balan, L.3
Foltyn, V.N.4
-
63
-
-
0032409042
-
Whole body autoradiographic study on the distribution of 14C-D-serine administered intravenously to rats
-
Imai K, Fukushima T, Santa T, Homma H, Huang Y, et al. (1998) Whole body autoradiographic study on the distribution of 14C-D-serine administered intravenously to rats. Amino Acids 15: 351-361.
-
(1998)
Amino Acids
, vol.15
, pp. 351-361
-
-
Imai, K.1
Fukushima, T.2
Santa, T.3
Homma, H.4
Huang, Y.5
-
64
-
-
0028275894
-
Functional neuronal ionotropic glutamate receptors are expressed in the non-neuronal cell line MIN6
-
Gonoi T, Mizuno N, Inagaki N, Kuromi H, Seino Y, et al. (1994) Functional neuronal ionotropic glutamate receptors are expressed in the non-neuronal cell line MIN6. J Biol Chem 269: 16989-16992.
-
(1994)
J Biol Chem
, vol.269
, pp. 16989-16992
-
-
Gonoi, T.1
Mizuno, N.2
Inagaki, N.3
Kuromi, H.4
Seino, Y.5
-
65
-
-
0029078886
-
Expression and role of ionotropic glutamate receptors in pancreatic islet cells
-
Inagaki N, Kuromi H, Gonoi T, Okamoto Y, Ishida H, et al. (1995) Expression and role of ionotropic glutamate receptors in pancreatic islet cells. Faseb J 9: 686-691.
-
(1995)
Faseb J
, vol.9
, pp. 686-691
-
-
Inagaki, N.1
Kuromi, H.2
Gonoi, T.3
Okamoto, Y.4
Ishida, H.5
-
66
-
-
0027302112
-
Glutamate stimulates glucagon secretion via an excitatory amino acid receptor of the AMPA subtype in rat pancreas
-
Bertrand G, Gross R, Puech R, Loubatieres-Mariani MM, Bockaert J (1993) Glutamate stimulates glucagon secretion via an excitatory amino acid receptor of the AMPA subtype in rat pancreas. Eur J Pharmacol 237: 45-50.
-
(1993)
Eur J Pharmacol
, vol.237
, pp. 45-50
-
-
Bertrand, G.1
Gross, R.2
Puech, R.3
Loubatieres-Mariani, M.M.4
Bockaert, J.5
-
67
-
-
0034655131
-
WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer
-
Bednarek AK, Laflin KJ, Daniel RL, Liao Q, Hawkins KA, et al. (2000) WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer. Cancer Res 60: 2140-2145.
-
(2000)
Cancer Res
, vol.60
, pp. 2140-2145
-
-
Bednarek, A.K.1
Laflin, K.J.2
Daniel, R.L.3
Liao, Q.4
Hawkins, K.A.5
-
68
-
-
17444440946
-
Common chromosomal fragile site FRA16D sequence: Identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells
-
Ried K, Finnis M, Hobson L, Mangelsdorf M, Dayan S, et al. (2000) Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells. Hum Mol Genet 9: 1651-1663.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 1651-1663
-
-
Ried, K.1
Finnis, M.2
Hobson, L.3
Mangelsdorf, M.4
Dayan, S.5
-
69
-
-
20144372911
-
Fragile genes as biomarkers: Epigenetic control of WWOX and FHIT in lung, breast and bladder cancer
-
Iliopoulos D, Guler G, Han SY, Johnston D, Druck T, et al. (2005) Fragile genes as biomarkers: epigenetic control of WWOX and FHIT in lung, breast and bladder cancer. Oncogene 24: 1625-1633.
-
(2005)
Oncogene
, vol.24
, pp. 1625-1633
-
-
Iliopoulos, D.1
Guler, G.2
Han, S.Y.3
Johnston, D.4
Druck, T.5
-
70
-
-
11144354718
-
The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis
-
Kuroki T, Yendamuri S, Trapasso F, Matsuyama A, Aqeilan RI, et al. (2004) The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis. Clin Cancer Res 10: 2459-2465.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2459-2465
-
-
Kuroki, T.1
Yendamuri, S.2
Trapasso, F.3
Matsuyama, A.4
Aqeilan, R.I.5
-
71
-
-
0035949591
-
WWOX: A candidate tumor suppressor gene involved in multiple tumor types
-
Paige AJ, Taylor KJ, Taylor C, Hillier SG, Farrington S, et al. (2001) WWOX: a candidate tumor suppressor gene involved in multiple tumor types. Proc Natl Acad Sci U S A 98: 11417-11422.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 11417-11422
-
-
Paige, A.J.1
Taylor, K.J.2
Taylor, C.3
Hillier, S.G.4
Farrington, S.5
-
72
-
-
0037089477
-
Genetic alterations of the tumor suppressor gene WWOX in esophageal squamous cell carcinoma
-
Kuroki T, Trapasso F, Shiraishi T, Alder H, Mimori K, et al. (2002) Genetic alterations of the tumor suppressor gene WWOX in esophageal squamous cell carcinoma. Cancer Res 62: 2258-2260.
-
(2002)
Cancer Res
, vol.62
, pp. 2258-2260
-
-
Kuroki, T.1
Trapasso, F.2
Shiraishi, T.3
Alder, H.4
Mimori, K.5
-
73
-
-
0037442728
-
WW domain containing oxidoreductase gene expression is altered in non-small cell lung cancer
-
Yendamuri S, Kuroki T, Trapasso F, Henry AC, Dumon KR, et al. (2003) WW domain containing oxidoreductase gene expression is altered in non-small cell lung cancer. Cancer Res 63: 878-881.
-
(2003)
Cancer Res
, vol.63
, pp. 878-881
-
-
Yendamuri, S.1
Kuroki, T.2
Trapasso, F.3
Henry, A.C.4
Dumon, K.R.5
-
74
-
-
0031045566
-
Rat maf related genes: Specific expression in chondrocytes, lens and spinal cord
-
Sakai M, Imaki J, Yoshida K, Ogata A, Matsushima-Hibaya Y, et al. (1997) Rat maf related genes: specific expression in chondrocytes, lens and spinal cord. Oncogene 14: 745-750.
-
(1997)
Oncogene
, vol.14
, pp. 745-750
-
-
Sakai, M.1
Imaki, J.2
Yoshida, K.3
Ogata, A.4
Matsushima-Hibaya, Y.5
-
75
-
-
0033616621
-
Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development
-
Kim JI, Li T, Ho IC, Grusby MJ, Glimcher LH (1999) Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development. Proc Natl Acad Sci U S A 96: 3781-3785.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 3781-3785
-
-
Kim, J.I.1
Li, T.2
Ho, I.C.3
Grusby, M.J.4
Glimcher, L.H.5
-
76
-
-
3142709424
-
Developmental contribution of c-maf in the kidney: Distribution and developmental study of c-maf mRNA in normal mice kidney and histological study of cmaf knockout mice kidney and liver
-
Imaki J, Tsuchiya K, Mishima T, Onodera H, Kim JI, et al. (2004) Developmental contribution of c-maf in the kidney: distribution and developmental study of c-maf mRNA in normal mice kidney and histological study of cmaf knockout mice kidney and liver. Biochem Biophys Res Commun 320: 1323-1327.
-
(2004)
Biochem Biophys Res Commun
, vol.320
, pp. 1323-1327
-
-
Imaki, J.1
Tsuchiya, K.2
Mishima, T.3
Onodera, H.4
Kim, J.I.5
-
77
-
-
0242416575
-
Cytokines and transcription factors that regulate T helper cell differentiation: New players and new insights
-
Agnello D, Lankford CS, Bream J, Morinobu A, Gadina M, et al. (2003) Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights. J Clin Immunol 23: 147-161.
-
(2003)
J Clin Immunol
, vol.23
, pp. 147-161
-
-
Agnello, D.1
Lankford, C.S.2
Bream, J.3
Morinobu, A.4
Gadina, M.5
-
78
-
-
0141570693
-
Regulation and differential expression of the c-maf gene in differentiating cultured cells
-
Serria MS, Ikeda H, Omoteyama K, Hirokawa J, Nishi S, et al. (2003) Regulation and differential expression of the c-maf gene in differentiating cultured cells. Biochem Biophys Res Commun 310: 318-326.
-
(2003)
Biochem Biophys Res Commun
, vol.310
, pp. 318-326
-
-
Serria, M.S.1
Ikeda, H.2
Omoteyama, K.3
Hirokawa, J.4
Nishi, S.5
-
79
-
-
33646842161
-
Potential roles of large mafs in cell lineages and developing pancreas
-
Tsuchiya M, Taniguchi S, Yasuda K, Nitta K, Maeda A, et al. (2006) Potential roles of large mafs in cell lineages and developing pancreas. Pancreas 32: 408-416.
-
(2006)
Pancreas
, vol.32
, pp. 408-416
-
-
Tsuchiya, M.1
Taniguchi, S.2
Yasuda, K.3
Nitta, K.4
Maeda, A.5
-
80
-
-
1542271011
-
-
Kataoka K, Shioda S, Ando K, Sakagami K, Handa H, et al. (2004) Differentially expressed Maf family transcription factors, c-Maf and MafA, activate glucagon and insulin gene expression in pancreatic islet alpha- and beta-cells. J Mol Endocrinol 32: 9-20.
-
Kataoka K, Shioda S, Ando K, Sakagami K, Handa H, et al. (2004) Differentially expressed Maf family transcription factors, c-Maf and MafA, activate glucagon and insulin gene expression in pancreatic islet alpha- and beta-cells. J Mol Endocrinol 32: 9-20.
-
-
-
-
81
-
-
36849075622
-
Pax-6 and c-Maf functionally interact with the alpha-cell-specific DNA element G1 in vivo to promote glucagon gene expression
-
Gosmain Y, Avril I, Mamin A, Philippe J (2007) Pax-6 and c-Maf functionally interact with the alpha-cell-specific DNA element G1 in vivo to promote glucagon gene expression. J Biol Chem 282: 35024-35034.
-
(2007)
J Biol Chem
, vol.282
, pp. 35024-35034
-
-
Gosmain, Y.1
Avril, I.2
Mamin, A.3
Philippe, J.4
-
82
-
-
59149097625
-
Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations
-
Meyre D, Delplanque J, Chevre JC, Lecoeur C, Lobbens S, et al. (2009) Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat Genet 41: 157-159.
-
(2009)
Nat Genet
, vol.41
, pp. 157-159
-
-
Meyre, D.1
Delplanque, J.2
Chevre, J.C.3
Lecoeur, C.4
Lobbens, S.5
-
83
-
-
0029854263
-
Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel
-
Sanguinetti MC, Curran ME, Zou A, Shen J, Spector PS, et al. (1996) Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel. Nature 384: 80-83.
-
(1996)
Nature
, vol.384
, pp. 80-83
-
-
Sanguinetti, M.C.1
Curran, M.E.2
Zou, A.3
Shen, J.4
Spector, P.S.5
-
84
-
-
0029952101
-
K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current
-
Barhanin J, Lesage F, Guillemare E, Fink M, Lazdunski M, et al. (1996) K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current. Nature 384: 78-80.
-
(1996)
Nature
, vol.384
, pp. 78-80
-
-
Barhanin, J.1
Lesage, F.2
Guillemare, E.3
Fink, M.4
Lazdunski, M.5
-
85
-
-
0031054075
-
A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome
-
Neyroud N, Tesson F, Denjoy I, Leibovici M, Donger C, et al. (1997) A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome. Nat Genet 15: 186-189.
-
(1997)
Nat Genet
, vol.15
, pp. 186-189
-
-
Neyroud, N.1
Tesson, F.2
Denjoy, I.3
Leibovici, M.4
Donger, C.5
-
86
-
-
9044240040
-
Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias
-
Wang Q, Curran ME, Splawski I, Burn TC, Millholland JM, et al. (1996) Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias. Nat Genet 12: 17-23.
-
(1996)
Nat Genet
, vol.12
, pp. 17-23
-
-
Wang, Q.1
Curran, M.E.2
Splawski, I.3
Burn, T.C.4
Millholland, J.M.5
-
87
-
-
0037428218
-
KCNQ1 gainof-function mutation in familial atrial fibrillation
-
Chen YH, Xu SJ, Bendahhou S, Wang XL, Wang Y, et al. (2003) KCNQ1 gainof-function mutation in familial atrial fibrillation. Science 299: 251-254.
-
(2003)
Science
, vol.299
, pp. 251-254
-
-
Chen, Y.H.1
Xu, S.J.2
Bendahhou, S.3
Wang, X.L.4
Wang, Y.5
-
88
-
-
0034518479
-
Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice
-
Lee MP, Ravenel JD, Hu RJ, Lustig LR, Tomaselli G, et al. (2000) Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice. J Clin Invest 106: 1447-1455.
-
(2000)
J Clin Invest
, vol.106
, pp. 1447-1455
-
-
Lee, M.P.1
Ravenel, J.D.2
Hu, R.J.3
Lustig, L.R.4
Tomaselli, G.5
-
89
-
-
0035020014
-
Differential expression of KvLQT1 and its regulator IsK in mouse epithelia
-
Demolombe S, Franco D, de Boer P, Kuperschmidt S, Roden D, et al. (2001) Differential expression of KvLQT1 and its regulator IsK in mouse epithelia. Am J Physiol Cell Physiol 280: C359-372.
-
(2001)
Am J Physiol Cell Physiol
, vol.280
-
-
Demolombe, S.1
Franco, D.2
de Boer, P.3
Kuperschmidt, S.4
Roden, D.5
-
90
-
-
0030799943
-
Properties of KvLQT1 K+ channel mutations in Romano-Ward and Jervell and Lange-Nielsen inherited cardiac arrhythmias
-
Chouabe C, Neyroud N, Guicheney P, Lazdunski M, Romey G, et al. (1997) Properties of KvLQT1 K+ channel mutations in Romano-Ward and Jervell and Lange-Nielsen inherited cardiac arrhythmias. Embo J 16: 5472-5479.
-
(1997)
Embo J
, vol.16
, pp. 5472-5479
-
-
Chouabe, C.1
Neyroud, N.2
Guicheney, P.3
Lazdunski, M.4
Romey, G.5
-
91
-
-
28344448471
-
Effects of I(Ks) channel inhibitors in insulin-secreting INS-1 cells
-
Ullrich S, Su J, Ranta F, Wittekindt OH, Ris F, et al. (2005) Effects of I(Ks) channel inhibitors in insulin-secreting INS-1 cells. Pflugers Arch 451: 428-436.
-
(2005)
Pflugers Arch
, vol.451
, pp. 428-436
-
-
Ullrich, S.1
Su, J.2
Ranta, F.3
Wittekindt, O.H.4
Ris, F.5
-
92
-
-
0035956935
-
Targeted disruption of the Kcnq1 gene produces a mouse model of Jervell and Lange-Nielsen Syndrome
-
Casimiro MC, Knollmann BC, Ebert SN, Vary JC Jr, Greene AE, et al. (2001) Targeted disruption of the Kcnq1 gene produces a mouse model of Jervell and Lange-Nielsen Syndrome. Proc Natl Acad Sci U S A 98: 2526-2531.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 2526-2531
-
-
Casimiro, M.C.1
Knollmann, B.C.2
Ebert, S.N.3
Vary Jr, J.C.4
Greene, A.E.5
-
93
-
-
67049115995
-
Enhanced insulin sensitivity of gene-targeted mice lacking functional KCNQ1
-
Boini KM, Graf D, Hennige AM, Koka S, Kempe DS, et al. (2009) Enhanced insulin sensitivity of gene-targeted mice lacking functional KCNQ1. Am J Physiol Regul Integr Comp Physiol 296: R1695-1701.
-
(2009)
Am J Physiol Regul Integr Comp Physiol
, vol.296
-
-
Boini, K.M.1
Graf, D.2
Hennige, A.M.3
Koka, S.4
Kempe, D.S.5
-
94
-
-
33646753192
-
Han Chinese cell and genome bank in Taiwan: Purpose, design and ethical considerations
-
Pan WH, Fann CS, Wu JY, Hung YT, Ho MS, et al. (2006) Han Chinese cell and genome bank in Taiwan: purpose, design and ethical considerations. HumHered 61: 27-30.
-
(2006)
HumHered
, vol.61
, pp. 27-30
-
-
Pan, W.H.1
Fann, C.S.2
Wu, J.Y.3
Hung, Y.T.4
Ho, M.S.5
|