Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk

Diabetes

Volumn 55, Issue 9, 2006, Pages 2640-2644

  Groves, Christopher J ^a   Zeggini, Eleftheria ^a,b   Minton, Jayne ^c   Frayling, Timothy M ^c   Weedon, Michael N ^c   Rayner, Nigel W ^a,b   Hitman, Graham A ^d   Walker, Mark ^e   Wiltshire, Steven ^b   Hattersley, Andrew T ^c   McCarthy, Mark I ^a,b  

^a CHURCHILL HOSPITAL   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c PENINSULA MEDICAL SCHOOL   (United Kingdom)

^d QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^e NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

SNP, single nucleotide polymorphism

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR 7 LIKE 2; T CELL FACTOR 4; T CELL FACTOR PROTEIN;

ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; FAMILY ASSESSMENT; FAMILY HISTORY; GENE FREQUENCY; GENE LOCUS; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOME; GENOTYPE; HIGH RISK POPULATION; HUMAN; MAJOR CLINICAL STUDY; MORBIDITY; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED KINGDOM; ADULT; AGED; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC PREDISPOSITION; GENETICS; MALE; MIDDLE AGED; POPULATION GENETICS; RISK FACTOR;

ADULT; AGED; DIABETES MELLITUS, TYPE 2; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENETICS, POPULATION; GENOTYPE; GREAT BRITAIN; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; TCF TRANSCRIPTION FACTORS;

EID: 33750602980     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db06-0355     Document Type: Article

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