TCF7L2 rs7903146 impairs islet function and morphology in non-diabetic individuals

Diabetologia

Volumn 55, Issue 10, 2012, Pages 2677-2681

  Le Bacquer, O ^a,b,c   Kerr Conte, J ^a,b   Gargani, S ^a,b   Delalleau, N ^a,b   Huyvaert, M ^a,c   Gmyr, V ^a,b   Froguel, P ^a,c,d   Neve, B ^a,c   Pattou, F ^a,b,e  

^a UNIV LILLE   (France)

^b Biotherapies for Diabetes   (France)

^c INSTITUT DE BIOLOGIE DE LILLE   (France)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e LILLE UNIVERSITY HOSPITAL   (France)

Author keywords

Human islet; Morphological analysis; Polymorphism; TCF7L2

Indexed keywords

C REACTIVE PROTEIN; DNA; GLUCAGON; HEMOGLOBIN A1C; INSULIN; TRANSCRIPTION FACTOR 7 LIKE 2; WNT PROTEIN;

ALLELE; ARTICLE; CELL SUBPOPULATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA POLYMORPHISM; GENETIC ANALYSIS; GENETIC VARIABILITY; GENOTYPE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INSULIN RELEASE; MORPHOMETRICS; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS;

ALLELES; CELLS, CULTURED; GENOTYPE; GLUCAGON; GLUCAGON-SECRETING CELLS; GLUCOSE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; POLYMORPHISM, SINGLE NUCLEOTIDE; RETROSPECTIVE STUDIES; TRANSCRIPTION FACTOR 7-LIKE 2 PROTEIN;

EID: 84866072918     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2660-8     Document Type: Article

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