-
1
-
-
2342466734
-
Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
-
Wild S, Roglic G, Green A, Sicree R, King H (2004) Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 27: 1047-1053.
-
(2004)
Diabetes Care
, vol.27
, pp. 1047-1053
-
-
Wild, S.1
Roglic, G.2
Green, A.3
Sicree, R.4
King, H.5
-
2
-
-
0033624575
-
The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
-
Altshuler D, Hirschhorn JN, Klannemark M, Lindgren CM, Vohl MC, et al. (2000) The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 26: 76-80.
-
(2000)
Nat Genet
, vol.26
, pp. 76-80
-
-
Altshuler, D.1
Hirschhorn, J.N.2
Klannemark, M.3
Lindgren, C.M.4
Vohl, M.C.5
-
3
-
-
0037317981
-
Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes
-
Gloyn AL, Weedon MN, Owen KR, Turner MJ, Knight BA, et al. (2003) Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes. Diabetes 52: 568-572.
-
(2003)
Diabetes
, vol.52
, pp. 568-572
-
-
Gloyn, A.L.1
Weedon, M.N.2
Owen, K.R.3
Turner, M.J.4
Knight, B.A.5
-
4
-
-
32544451924
-
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
-
Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, et al. (2006) Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 38: 320-323.
-
(2006)
Nat Genet
, vol.38
, pp. 320-323
-
-
Grant, S.F.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Manolescu, A.5
-
5
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PI, et al. (2007) Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316: 1331-1336.
-
(2007)
Science
, vol.316
, pp. 1331-1336
-
-
Saxena, R.1
Voight, B.F.2
Lyssenko, V.3
Burtt, N.P.4
de Bakker, P.I.5
-
6
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, et al. (2007) A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 316: 889-894.
-
(2007)
Science
, vol.316
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
Zeggini, E.4
Freathy, R.M.5
-
7
-
-
34249885875
-
A genomewide association study of type 2 diabetes in Finns detects multiple susceptibility variants
-
Scott LJ, Mohlke KL, Bonnycastle LL, Willer CJ, Li Y, et al. (2007) A genomewide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 316: 1341-1345.
-
(2007)
Science
, vol.316
, pp. 1341-1345
-
-
Scott, L.J.1
Mohlke, K.L.2
Bonnycastle, L.L.3
Willer, C.J.4
Li, Y.5
-
8
-
-
33847176604
-
A genome-wide association study identifies novel risk loci for type 2 diabetes
-
Sladek R, Rocheleau G, Rung J, Dina C, Shen L, et al. (2007) A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 445: 881-885.
-
(2007)
Nature
, vol.445
, pp. 881-885
-
-
Sladek, R.1
Rocheleau, G.2
Rung, J.3
Dina, C.4
Shen, L.5
-
9
-
-
34249828965
-
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
-
Steinthorsdottir V, Thorleifsson G, Reynisdottir I, Benediktsson R, Jonsdottir T, et al. (2007) A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet 39: 770-775.
-
(2007)
Nat Genet
, vol.39
, pp. 770-775
-
-
Steinthorsdottir, V.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Jonsdottir, T.5
-
10
-
-
34249895023
-
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
-
Zeggini E, Weedon MN, Lindgren CM, Frayling TM, Elliott KS, et al. (2007) Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 316: 1336-1341.
-
(2007)
Science
, vol.316
, pp. 1336-1341
-
-
Zeggini, E.1
Weedon, M.N.2
Lindgren, C.M.3
Frayling, T.M.4
Elliott, K.S.5
-
11
-
-
34547510624
-
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes
-
Gudmundsson J, Sulem P, Steinthorsdottir V, Bergthorsson JT, Thorleifsson G, et al. (2007) Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet 39: 977-983.
-
(2007)
Nat Genet
, vol.39
, pp. 977-983
-
-
Gudmundsson, J.1
Sulem, P.2
Steinthorsdottir, V.3
Bergthorsson, J.T.4
Thorleifsson, G.5
-
12
-
-
42349106044
-
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
-
Zeggini E, Scott LJ, Saxena R, Voight BF, Marchini JL, et al. (2008) Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 40: 638-645.
-
(2008)
Nat Genet
, vol.40
, pp. 638-645
-
-
Zeggini, E.1
Scott, L.J.2
Saxena, R.3
Voight, B.F.4
Marchini, J.L.5
-
13
-
-
44349166252
-
Common genetic variation near MC4R is associated with waist circumference and insulin resistance
-
Chambers JC, Elliott P, Zabaneh D, Zhang W, Li Y, et al. (2008) Common genetic variation near MC4R is associated with waist circumference and insulin resistance. Nat Genet 40: 716-718.
-
(2008)
Nat Genet
, vol.40
, pp. 716-718
-
-
Chambers, J.C.1
Elliott, P.2
Zabaneh, D.3
Zhang, W.4
Li, Y.5
-
14
-
-
44349142294
-
Common variants near MC4R are associated with fat mass, weight and risk of obesity
-
Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, et al. (2008) Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 40: 768-775.
-
(2008)
Nat Genet
, vol.40
, pp. 768-775
-
-
Loos, R.J.1
Lindgren, C.M.2
Li, S.3
Wheeler, E.4
Zhao, J.H.5
-
15
-
-
42449159284
-
Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study
-
Palmer ND, Goodarzi MO, Langefeld CD, Ziegler J, Norris JM, et al. (2008) Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study. Diabetes 57: 1093-1100.
-
(2008)
Diabetes
, vol.57
, pp. 1093-1100
-
-
Palmer, N.D.1
Goodarzi, M.O.2
Langefeld, C.D.3
Ziegler, J.4
Norris, J.M.5
-
16
-
-
38849129636
-
-
PLoS
-
Staiger H, Machicao F, Stefan N, Tschritter O, Thamer C, et al. (2007) Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function. PLoS ONE 2: e832.
-
(2007)
Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function
, vol.ONE 2
-
-
Staiger, H.1
Machicao, F.2
Stefan, N.3
Tschritter, O.4
Thamer, C.5
-
17
-
-
36849011549
-
Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: Validation and extension of genome-wide association studies
-
Grarup N, Rose CS, Andersson EA, Andersen G, Nielsen AL, et al. (2007) Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies. Diabetes 56: 3105-3111.
-
(2007)
Diabetes
, vol.56
, pp. 3105-3111
-
-
Grarup, N.1
Rose, C.S.2
Andersson, E.A.3
Andersen, G.4
Nielsen, A.L.5
-
18
-
-
53549096229
-
Positive association between variations in CDKAL1 and type 2 diabetes in Han Chinese individuals
-
Liu Y, Yu L, Zhang D, Chen Z, Zhou DZ, et al. (2008) Positive association between variations in CDKAL1 and type 2 diabetes in Han Chinese individuals. Diabetologia 51: 2134-2137.
-
(2008)
Diabetologia
, vol.51
, pp. 2134-2137
-
-
Liu, Y.1
Yu, L.2
Zhang, D.3
Chen, Z.4
Zhou, D.Z.5
-
19
-
-
50449104632
-
Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians
-
Ng MC, Park KS, Oh B, Tam CH, Cho YM, et al. (2008) Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians. Diabetes 57: 2226-2233.
-
(2008)
Diabetes
, vol.57
, pp. 2226-2233
-
-
Ng, M.C.1
Park, K.S.2
Oh, B.3
Tam, C.H.4
Cho, Y.M.5
-
20
-
-
56349170898
-
Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population
-
Wu Y, Li H, Loos RJ, Yu Z, Ye X, et al. (2008) Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population. Diabetes 57: 2834-2842.
-
(2008)
Diabetes
, vol.57
, pp. 2834-2842
-
-
Wu, Y.1
Li, H.2
Loos, R.J.3
Yu, Z.4
Ye, X.5
-
21
-
-
64149094603
-
-
diabetes and fasting plasma glucose in Han Chinese individuals. Diabetologia
-
Ronn T, Wen J, Yang Z, Lu B, Du Y, et al. (2009) A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals. Diabetologia.
-
(2009)
A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type
, vol.2
-
-
Ronn, T.1
Wen, J.2
Yang, Z.3
Lu, B.4
Du, Y.5
-
22
-
-
34548765645
-
Replication and identification of novel variants at TCF7L2 associated with type 2 diabetes in Hong Kong Chinese
-
Ng MC, Tam CH, Lam VK, So WY, Ma RC, et al. (2007) Replication and identification of novel variants at TCF7L2 associated with type 2 diabetes in Hong Kong Chinese. J Clin Endocrinol Metab 92: 3733-3737.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 3733-3737
-
-
Ng, M.C.1
Tam, C.H.2
Lam, V.K.3
So, W.Y.4
Ma, R.C.5
-
23
-
-
34948845069
-
Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population
-
Chang YC, Chang TJ, Jiang YD, Kuo SS, Lee KC, et al. (2007) Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population. Diabetes 56: 2631-2637.
-
(2007)
Diabetes
, vol.56
, pp. 2631-2637
-
-
Chang, Y.C.1
Chang, T.J.2
Jiang, Y.D.3
Kuo, S.S.4
Lee, K.C.5
-
24
-
-
44749093346
-
Exon sequencing and association analysis of polymorphisms in TCF7L2 with type 2 diabetes in a Chinese population
-
Ren Q, Han XY, Wang F, Zhang XY, Han LC, et al. (2008) Exon sequencing and association analysis of polymorphisms in TCF7L2 with type 2 diabetes in a Chinese population. Diabetologia 51: 1146-1152.
-
(2008)
Diabetologia
, vol.51
, pp. 1146-1152
-
-
Ren, Q.1
Han, X.Y.2
Wang, F.3
Zhang, X.Y.4
Han, L.C.5
-
25
-
-
0031851293
-
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
-
Alberti KG, Zimmet PZ (1998) Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 15: 539-553.
-
(1998)
Diabet Med
, vol.15
, pp. 539-553
-
-
Alberti, K.G.1
Zimmet, P.Z.2
-
26
-
-
12244264435
-
Genetic Power Calculator: Design of linkage and association genetic mapping studies of complex traits
-
Purcell S, Cherny SS, Sham PC (2003) Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics 19: 149-150.
-
(2003)
Bioinformatics
, vol.19
, pp. 149-150
-
-
Purcell, S.1
Cherny, S.S.2
Sham, P.C.3
-
27
-
-
33751369509
-
Common variants in the TCF7L2 gene and predisposition to type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and women
-
Humphries SE, Gable D, Cooper JA, Ireland H, Stephens JW, et al. (2006) Common variants in the TCF7L2 gene and predisposition to type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and women. J Mol Med 84: 1005-1014.
-
(2006)
J Mol Med
, vol.84
, pp. 1005-1014
-
-
Humphries, S.E.1
Gable, D.2
Cooper, J.A.3
Ireland, H.4
Stephens, J.W.5
-
28
-
-
33750594321
-
Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes in large cohorts of U.S. women and men
-
Zhang C, Qi L, Hunter DJ, Meigs JB, Manson JE, et al. (2006) Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes in large cohorts of U.S. women and men. Diabetes 55: 2645-2648.
-
(2006)
Diabetes
, vol.55
, pp. 2645-2648
-
-
Zhang, C.1
Qi, L.2
Hunter, D.J.3
Meigs, J.B.4
Manson, J.E.5
-
29
-
-
33845936147
-
Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population
-
Chandak GR, Janipalli CS, Bhaskar S, Kulkarni SR, Mohankrishna P, et al. (2007) Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population. Diabetologia 50: 63-67.
-
(2007)
Diabetologia
, vol.50
, pp. 63-67
-
-
Chandak, G.R.1
Janipalli, C.S.2
Bhaskar, S.3
Kulkarni, S.R.4
Mohankrishna, P.5
-
30
-
-
33750889376
-
Transcription factor TCF7L2 genetic study in the French population: Expression in human beta-cells and adipose tissue and strong association with type 2 diabetes
-
Cauchi S, Meyre D, Dina C, Choquet H, Samson C, et al. (2006) Transcription factor TCF7L2 genetic study in the French population: expression in human beta-cells and adipose tissue and strong association with type 2 diabetes. Diabetes 55: 2903-2908.
-
(2006)
Diabetes
, vol.55
, pp. 2903-2908
-
-
Cauchi, S.1
Meyre, D.2
Dina, C.3
Choquet, H.4
Samson, C.5
-
31
-
-
79959503826
-
-
The International HapMap Project
-
(2003) The International HapMap Project. Nature 426: 789-796.
-
Nature
, vol.426
, pp. 789-796
-
-
-
32
-
-
34147119644
-
Replication study for the association of TCF7L2 with susceptibility to type 2 diabetes in a Japanese population
-
Hayashi T, Iwamoto Y, Kaku K, Hirose H, Maeda S (2007) Replication study for the association of TCF7L2 with susceptibility to type 2 diabetes in a Japanese population. Diabetologia 50: 980-984.
-
(2007)
Diabetologia
, vol.50
, pp. 980-984
-
-
Hayashi, T.1
Iwamoto, Y.2
Kaku, K.3
Hirose, H.4
Maeda, S.5
-
33
-
-
33847618213
-
A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population
-
Horikoshi M, Hara K, Ito C, Nagai R, Froguel P, et al. (2007) A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population. Diabetologia 50: 747-751.
-
(2007)
Diabetologia
, vol.50
, pp. 747-751
-
-
Horikoshi, M.1
Hara, K.2
Ito, C.3
Nagai, R.4
Froguel, P.5
-
34
-
-
34547625955
-
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
-
Scuteri A, Sanna S, Chen WM, Uda M, Albai G, et al. (2007) Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet 3: e115.
-
(2007)
PLoS Genet
, vol.3
-
-
Scuteri, A.1
Sanna, S.2
Chen, W.M.3
Uda, M.4
Albai, G.5
-
35
-
-
35848945259
-
Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population
-
Horikoshi M, Hara K, Ito C, Shojima N, Nagai R, et al. (2007) Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population. Diabetologia 50: 2461-2466.
-
(2007)
Diabetologia
, vol.50
, pp. 2461-2466
-
-
Horikoshi, M.1
Hara, K.2
Ito, C.3
Shojima, N.4
Nagai, R.5
-
36
-
-
38449097877
-
Variants in the fat mass- and obesity-associated (FTO) gene are not associated with obesity in a Chinese Han population
-
Li H, Wu Y, Loos RJ, Hu FB, Liu Y, et al. (2008) Variants in the fat mass- and obesity-associated (FTO) gene are not associated with obesity in a Chinese Han population. Diabetes 57: 264-268.
-
(2008)
Diabetes
, vol.57
, pp. 264-268
-
-
Li, H.1
Wu, Y.2
Loos, R.J.3
Hu, F.B.4
Liu, Y.5
-
37
-
-
58149470594
-
FTO gene variants are strongly associated with type 2 diabetes in South Asian Indians
-
Yajnik CS, Janipalli CS, Bhaskar S, Kulkarni SR, Freathy RM, et al. (2009) FTO gene variants are strongly associated with type 2 diabetes in South Asian Indians. Diabetologia 52: 247-252.
-
(2009)
Diabetologia
, vol.52
, pp. 247-252
-
-
Yajnik, C.S.1
Janipalli, C.S.2
Bhaskar, S.3
Kulkarni, S.R.4
Freathy, R.M.5
|