Plasma homocysteine concentrations and risk of coronary heart disease in UK Indian Asian and European men

Lancet

Volumn 355, Issue 9203, 2000, Pages 523-527

  Chambers, John C ^a,c   Obeid, Omar A ^d   Refsum, Helga ^g   Ueland, Per ^g   Hackett, David ^e   Hooper, James ^f   Turner, Rebecca M ^b   Thompson, Simon G ^b   Kooner, Jaspal S ^a,c  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^c EALING HOSPITAL   (United Kingdom)

^d ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^e Hemel Hempstead General Hospital   (United Kingdom)

^f ROYAL BROMPTON HOSPITAL   (United Kingdom)

^g UNIVERSITY OF BERGEN   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE;

ADULT; AMINO ACID BLOOD LEVEL; ARTICLE; ASIAN; CARDIOVASCULAR RISK; CONTROLLED STUDY; DIET SUPPLEMENTATION; ETHNIC GROUP; FOLIC ACID BLOOD LEVEL; HUMAN; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; RISK FACTOR; UNITED KINGDOM; VITAMIN BLOOD LEVEL; VITAMIN INTAKE;

EID: 0034639623     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(99)93019-2     Document Type: Article

References (23)

1. Balarajan R. Ethnicity and variations in mortality from coronary heart disease. Health Trends. 28:1996;45-51.
2. McKeigue P.M., Shah B., Marmot M.G. Relation of central obesity and insulin resistance with high diabetes prevalance and cardiovascular risk in South Asians. Lancet. 337:1991;382-386.
3. McKeigue P.M., Ferrie J.E., Pierpoint T., Marmot M.G. Association of early-onset coronary heart disease in South Asian men with glucose intolerance and hyperinsulinemia. Circulation. 87:1993;152-161.
4. Mather H.M., Keen H. The Southall Diabetes Survey: prevalence of known diabetes in Asians and Europeans. BMJ. 291:1985;1081-1084.
5. Kooner J.S. Coronary heart disease in UK Indian Asians - the potential for prevention. Heart. 78:1997;530-532.
6. Hankey J.H., Eikelboom J.W. Homocysteine and vascular disease. Lancet. 354:1999;407-413.
7. Clarke R., Daly L., Robinson K.et al. Hyperhomocysteinaemia: an independent risk factor for vascular disease. N Engl J Med. 324:1991;1149-1155.
8. Graham I.M., Daly L.E., Refsum H.M.et al. Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project. JAMA. 277:1997;1775-1781.
9. Nygard O., Nodrehaug J.E., Refsum H., Ueland P.M., Farstad M., Vollset S.E. Plasma homocysteine levels and mortality in patients with coronary artery disease. N Engl J Med. 337:1997;230-236.
10. Stampfer M.J., Malinow M.R., Willett W.C.et al. A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians. JAMA. 268:1992;877-881.
11. Perry I.J., Refsum H., Morris R.W., Ebrahim S.B., Ueland P.M., Shaper A.G. Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men. Lancet. 346:1995;1395-1398.
12. Boushey C.J., Beresford S.A., Omenn G.S., Motulsky A.G. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease: probable benefits of increasing folic acid intakes. JAMA. 274:1995;1049-1057.
13. Abraham R., Brown M.C., North W.R., McFadyen I.R. Diets of Asian pregnant women in Harrow: iron and vitamins. Hum Nutr Appl Nutr. 41:1987;164-173.
14. Matthews J.H., Wood J.K. Megaloblastic anaemia in vegetarian Asians. Clin Lab Haematol. 6:1984;1-7.
15. Fiskerstrand T., Refsum H., Kvalheim G., Ueland P.M. Homocysteine and other thiols in plasma and urine: automated determination and sample stability. Clin Chem. 39:1993;263-271.
16. Altman D. Practical statistics for medical research. 1997;Chapman and Hall, London.
17. Evans R.W., Shaten B.J., Hempel J.D., Cutler J.A., Kuller L.H. Homocyst(e)ine and risk of cardiovascular disease in the Multiple Risk Factor Intervention Trial. Arterioscler Thromb Vasc Biol. 17:1997;1947-1953.
18. Armitage, P., Berry, G. Statistical methods in medical research. Oxford: Blackwell Scientific Publications, 1987: 91-92.
19. Clarke R., Woodhouse P., Ulvik A.et al. Variability and determinants of total homocysteine concentrations in plasma in an elderly population. Clin Chem. 44:1998;102-107.
20. MacMahon S., Peto R., Cutler J.et al. Blood pressure, stroke, and coronary heart disease. Part 1, prolonged difference in blood pressure: prospective observational studies corrected for the regression dilution bias. Lancet. 335:1990;765-774.
21. Danesh J., Lewington S. Plasma homocysteine and coronary heart disease: systematic review of published epidemiological studies. J Cardiovasc Risk. 5:1998;229-232.
22. Dawson D.W., Waters H.M. Malnutrition: folate and cobalamin deficiency. Br J Biomed Sci. 51:1994;221-227.
23. Lowering blood homocysteine wth folic acid based supplements: meta-analysis of randomised trials. BMJ. 316:1998;894-898.