Multidrug resistance and efflux pumps: Insights from molecular dynamics simulations

Current Topics in Medicinal Chemistry

Volumn 13, Issue 24, 2013, Pages 3165-3183

  Collu, Francesca ^a   Cascella, Michele ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Active transport; ATP binding cassette; Computational structural biology; Major facilitator superfamily; Multidrug and toxic compound extrusion; Resistance nodulation division

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; BACTERIAL PROTEIN; IMIPENEM; MEMBRANE FUSION PROTEIN; MEROPENEM; MEXA PROTEIN; MEXB PROTEIN; MSBA PROTEIN; MULTIDRUG RESISTANCE PROTEIN; OPRM PROTEIN; SAV1866 PROTEIN; UNCLASSIFIED DRUG;

BACTERIAL PHENOMENA AND FUNCTIONS; BINDING AFFINITY; CONFORMATION; CRYSTAL STRUCTURE; EFFLUX PUMP; GENE MUTATION; HYDROGEN BOND; HYDROPHOBICITY; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MULTIDRUG RESISTANCE; PROTEIN STRUCTURE; PROTON TRANSPORT; RESISTANCE NODULATION DIVISION EFFLUX PUMP; REVIEW; SIMULATION;

ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; BIOLOGICAL TRANSPORT; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI PROTEINS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR DYNAMICS SIMULATION; P-GLYCOPROTEIN;

EID: 84890961488     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/15680266113136660224     Document Type: Review

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