A novel MATE family efflux pump contributes to the reduced susceptibility of laboratory-derived Staphylococcus aureus mutants to tigecycline

Antimicrobial Agents and Chemotherapy

Volumn 49, Issue 5, 2005, Pages 1865-1871

  McAleese, Fionnuala ^a,c   Petersen, Peter ^a   Ruzin, Alexey ^a   Dunman, Paul M ^a,c   Murphy, Ellen ^a   Projan, Steven J ^b   Bradford, Patricia A ^a  

^a WYETH RESEARCH   (United States)

^b Bldg 200 ^*

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 DEOXY 7 DIMETHYLAMINO 9 (N,N DIMETHYLGLYCINAMIDO) 6 NORTETRACYCLINE; 9 N,N DIMETHYLGLYCINAMIDO 6 NOR 6 DEOXYTETRACYCLINE; AMPICILLIN; BACTERIAL PROTEIN; CHLORAMPHENICOL; CIPROFLOXACIN; ERYTHROMYCIN; ETHIDIUM BROMIDE; IMIPENEM; KANAMYCIN; LEVOFLOXACIN; MINOCYCLINE; NORFLOXACIN; OXACILLIN; PIPERACILLIN PLUS TAZOBACTAM; PROTEIN MATE; TETRACYCLINE; TETRAPHENYLPHOSPHONIUM; TIGECYCLINE; TOBRAMYCIN; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIUM MUTANT; DNA FINGERPRINTING; DRUG SENSITIVITY; GENE CLUSTER; GENE DELETION; GENE OVEREXPRESSION; GENETIC COMPLEMENTATION; MAPA GENE; MEPR GENE; MEPRAB GENE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; REPRESSOR GENE; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; DNA PROBES; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; MICROBIAL SENSITIVITY TESTS; MINOCYCLINE; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLASMIDS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, BACTERIAL; STAPHYLOCOCCUS AUREUS;

EID: 18244403495     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.49.5.1865-1871.2005     Document Type: Article

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