-
1
-
-
0032949426
-
The multidrug efflux protein NorM is a prototype of a new family of transporters
-
Brown, M. H., Paulsen, I. T. & Skurray, R. A. The multidrug efflux protein NorM is a prototype of a new family of transporters. Mol. Microbiol. 31, 394-395 (1999).
-
(1999)
Mol. Microbiol.
, vol.31
, pp. 394-395
-
-
Brown, M.H.1
Paulsen, I.T.2
Skurray, R.A.3
-
2
-
-
0346991732
-
1-coupled multidrug efflux pump, PmpM, a member of the MATE family of transporters, from Pseudomonas aeruginosa
-
1-coupled multidrug efflux pump, PmpM, a member of the MATE family of transporters, from Pseudomonas aeruginosa. J. Bacteriol. 186, 262-265 (2004).
-
(2004)
J. Bacteriol.
, vol.186
, pp. 262-265
-
-
He, G.X.1
-
3
-
-
18244388696
-
Multidrug resistance in Staphylococcus aureus due to overexpression of a novel multidrug and toxin extrusion (MATE) transport protein
-
Kaatz, G. W., McAleese, F. & Seo, S. M. Multidrug resistance in Staphylococcus aureus due to overexpression of a novel multidrug and toxin extrusion (MATE) transport protein. Antimicrob. Agents Chemother. 49, 1857-1864 (2005).
-
(2005)
Antimicrob. Agents Chemother.
, vol.49
, pp. 1857-1864
-
-
Kaatz, G.W.1
McAleese, F.2
Seo, S.M.3
-
4
-
-
18244403495
-
A novel MATE family efflux pump contributes to the reduced susceptibility of laboratory-derived Staphylococcus aureus mutants to tigecycline
-
McAleese, F. et al. A novel MATE family efflux pump contributes to the reduced susceptibility of laboratory-derived Staphylococcus aureus mutants to tigecycline. Antimicrob. Agents Chemother. 49, 1865-1871 (2005).
-
(2005)
Antimicrob. Agents Chemother.
, vol.49
, pp. 1865-1871
-
-
McAleese, F.1
-
5
-
-
33846854920
-
1/organic cation antiporter MATE1
-
1/organic cation antiporter MATE1. Am. J. Physiol. 292, F593-F598 (2007).
-
(2007)
Am. J. Physiol.
, vol.292
-
-
Tsuda, M.1
-
6
-
-
62749133967
-
Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect ofmetformininpatients with diabetes: A preliminary study
-
Becker, M. L. et al. Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect ofmetformininpatients with diabetes: a preliminary study. Diabetes 58, 745-749 (2009).
-
(2009)
Diabetes
, vol.58
, pp. 745-749
-
-
Becker, M.L.1
-
7
-
-
79955092770
-
Interactions of tyrosine kinase inhibitors with organic cation transporters and multidrug and toxic compound extrusion proteins
-
Minematsu, T. & Giacomini, K. M. Interactions of tyrosine kinase inhibitors with organic cation transporters and multidrug and toxic compound extrusion proteins. Mol. Cancer Ther. 10, 531-539 (2011).
-
(2011)
Mol. Cancer Ther.
, vol.10
, pp. 531-539
-
-
Minematsu, T.1
Giacomini, K.M.2
-
8
-
-
77949675459
-
Potent and specific inhibition of mMate1-mediated efflux of type i organic cations in the liver and kidney by pyrimethamine
-
Ito, S. et al. Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine. J. Pharmacol. Exp. Ther. 333, 341-350 (2010).
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.333
, pp. 341-350
-
-
Ito, S.1
-
9
-
-
79956333806
-
Effects of a MATE protein inhibitor, pyrimethamine, on the renal elimination of metformin at oral microdose and at therapeutic dose in healthy subjects
-
Kusuhara, H. et al. Effects of a MATE protein inhibitor, pyrimethamine, on the renal elimination of metformin at oral microdose and at therapeutic dose in healthy subjects. Clin. Pharmacol. Ther. 89, 837-844 (2011).
-
(2011)
Clin. Pharmacol. Ther.
, vol.89
, pp. 837-844
-
-
Kusuhara, H.1
-
10
-
-
33748644877
-
Structure of a bacterial multidrug ABC transporter
-
Dawson, R. J. & Locher, K. P. Structure of a bacterial multidrug ABC transporter. Nature 443, 180-185 (2006).
-
(2006)
Nature
, vol.443
, pp. 180-185
-
-
Dawson, R.J.1
Locher, K.P.2
-
11
-
-
33748670458
-
Crystal structures of a multidrug transporter reveal a functionally rotating mechanism
-
Murakami, S., Nakashima, R., Yamashita, E., Matsumoto, T. & Yamaguchi, A. Crystal structures of a multidrug transporter reveal a functionally rotating mechanism. Nature 443, 173-179 (2006).
-
(2006)
Nature
, vol.443
, pp. 173-179
-
-
Murakami, S.1
Nakashima, R.2
Yamashita, E.3
Matsumoto, T.4
Yamaguchi, A.5
-
12
-
-
65749116076
-
Active efflux as the multidrug resistance mechanism
-
Wasaznik, A., Grinholc, M. & Bielawski, K. P. Active efflux as the multidrug resistance mechanism. Postepy Hig. Med. Dosw. 63, 123-133 (2009).
-
(2009)
Postepy Hig. Med. Dosw.
, vol.63
, pp. 123-133
-
-
Wasaznik, A.1
Grinholc, M.2
Bielawski, K.P.3
-
13
-
-
0031836031
-
NorM, a putative multidrug efflux protein, of Vibrio parahaemolyticus andits homologinEscherichia coli
-
Morita, Y. et al. NorM, a putative multidrug efflux protein, of Vibrio parahaemolyticus andits homologinEscherichia coli. Antimicrob. Agents Chemother. 42, 1778-1782 (1998).
-
(1998)
Antimicrob. Agents Chemother.
, vol.42
, pp. 1778-1782
-
-
Morita, Y.1
-
15
-
-
14244266607
-
1/multidrug antiporter in Vibrio parahaemolyticus
-
1/multidrug antiporter in Vibrio parahaemolyticus. J. Bacteriol. 187, 1552-1558 (2005).
-
(2005)
J. Bacteriol.
, vol.187
, pp. 1552-1558
-
-
Otsuka, M.1
-
16
-
-
77958596325
-
Structure of a cation-bound multidrug and toxic compound extrusion transporter
-
He, X. et al. Structure of a cation-bound multidrug and toxic compound extrusion transporter. Nature 467, 991-994 (2010).
-
(2010)
Nature
, vol.467
, pp. 991-994
-
-
He, X.1
-
17
-
-
53849119555
-
Ins and outs of major facilitator superfamily antiporters
-
Law, C. J., Maloney, P. C. & Wang, D. N. Ins and outs of major facilitator superfamily antiporters. Annu. Rev. Microbiol. 62, 289-305 (2008).
-
(2008)
Annu. Rev. Microbiol.
, vol.62
, pp. 289-305
-
-
Law, C.J.1
Maloney, P.C.2
Wang, D.N.3
-
18
-
-
80052089906
-
Lipidic cubic phase technologies for membrane protein structural studies
-
Cherezov, V. Lipidic cubic phase technologies for membrane protein structural studies. Curr. Opin. Struct. Biol. 21, 559-566 (2011).
-
(2011)
Curr. Opin. Struct. Biol.
, vol.21
, pp. 559-566
-
-
Cherezov, V.1
-
19
-
-
84859627442
-
Ribosomal production and in vitro selection of natural product-like peptidomimetics: The FIT and RaPID systems
-
Hipolito, C. J. & Suga, H. Ribosomal production and in vitro selection of natural product-like peptidomimetics: the FIT and RaPID systems. Curr. Opin. Chem. Biol. 16, 196-203 (2012).
-
(2012)
Curr. Opin. Chem. Biol.
, vol.16
, pp. 196-203
-
-
Hipolito, C.J.1
Suga, H.2
-
20
-
-
84858657128
-
In vitro selection of anti-Akt2 thioether-macrocyclic peptides leading to isoform-selective inhibitors
-
Hayashi, Y., Morimoto, J. & Suga, H. In vitro selection of anti-Akt2 thioether-macrocyclic peptides leading to isoform-selective inhibitors. ACS Chem. Biol. 7, 607-613 (2012).
-
(2012)
ACS Chem. Biol.
, vol.7
, pp. 607-613
-
-
Hayashi, Y.1
Morimoto, J.2
Suga, H.3
-
21
-
-
84555190565
-
Natural product-like macrocyclic N-methyl-peptide inhibitors against a ubiquitin ligase uncovered from a ribosome-expressed de novo library
-
Yamagishi, Y. et al. Natural product-like macrocyclic N-methyl-peptide inhibitors against a ubiquitin ligase uncovered from a ribosome-expressed de novo library. Chem. Biol. 18, 1562-1570 (2011).
-
(2011)
Chem. Biol.
, vol.18
, pp. 1562-1570
-
-
Yamagishi, Y.1
-
22
-
-
84859239807
-
Discoveryof macrocyclic peptides armed with a mechanism-based warhead: Isoform-selective inhibition of human deacetylase SIRT2
-
Morimoto, J., Hayashi, Y. & Suga, H. Discoveryof macrocyclic peptides armed with a mechanism-based warhead: isoform-selective inhibition of human deacetylase SIRT2. Angew. Chem. Int. Ed. 51, 3423-3427 (2012).
-
(2012)
Angew. Chem. Int. Ed.
, vol.51
, pp. 3423-3427
-
-
Morimoto, J.1
Hayashi, Y.2
Suga, H.3
-
23
-
-
27144489108
-
Protein database searches using compositionally adjusted substitution matrices
-
Altschul, S. F. et al. Protein database searches using compositionally adjusted substitution matrices. FEBS J. 272, 5101-5109 (2005).
-
(2005)
FEBS J.
, vol.272
, pp. 5101-5109
-
-
Altschul, S.F.1
-
24
-
-
0019252702
-
Structure-activity relationships of antibacterial 6, 7-and 7, 8-disubstituted 1-alkyl-1, 4-dihydro-4-oxoquinoline-3-carboxylic acids
-
Koga, H., Itoh, A., Murayama, S., Suzue, S. & Irikura, T. Structure-activity relationships of antibacterial 6, 7-and 7, 8-disubstituted 1-alkyl-1, 4-dihydro-4-oxoquinoline-3-carboxylic acids. J. Med. Chem. 23, 1358-1363 (1980).
-
(1980)
J. Med. Chem.
, vol.23
, pp. 1358-1363
-
-
Koga, H.1
Itoh, A.2
Murayama, S.3
Suzue, S.4
Irikura, T.5
-
25
-
-
84873431135
-
1-coupled, substrate-bound MATE multidrug transporter
-
1-coupled, substrate-bound MATE multidrug transporter. Proc. Natl Acad. Sci. USA 110, 2099-2104 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 2099-2104
-
-
Lu, M.1
-
26
-
-
73449131843
-
The ID23-2 structural biology microfocus beamline at the ESRF
-
Flot, D. et al. The ID23-2 structural biology microfocus beamline at the ESRF. J. Synchrotron Radiat. 17, 107-118 (2010).
-
(2010)
J. Synchrotron Radiat.
, vol.17
, pp. 107-118
-
-
Flot, D.1
-
27
-
-
0024300293
-
Intracellular pHofhalobacteria can be determined by the fluorescent dye 29, 79-bis (carboxyethyl)-5 (6)-carboxyfluorescein
-
Tsujimoto, K., Semadeni, M., Huflejt, M. & Packer, L. Intracellular pHofhalobacteria can be determined by the fluorescent dye 29, 79-bis (carboxyethyl)-5 (6)-carboxyfluorescein. Biochem. Biophys. Res. Commun. 155, 123-129 (1988).
-
(1988)
Biochem. Biophys. Res. Commun.
, vol.155
, pp. 123-129
-
-
Tsujimoto, K.1
Semadeni, M.2
Huflejt, M.3
Packer, L.4
-
28
-
-
12244293832
-
Contributions of MexAB-OprM and an EmrE homolog to intrinsic resistance of Pseudomonas aeruginosa to aminoglycosides and dyes
-
Li, X. Z., Poole, K. & Nikaido, H. Contributions of MexAB-OprM and an EmrE homolog to intrinsic resistance of Pseudomonas aeruginosa to aminoglycosides and dyes. Antimicrob. Agents Chemother. 47, 27-33 (2003).
-
(2003)
Antimicrob. Agents Chemother.
, vol.47
, pp. 27-33
-
-
Li, X.Z.1
Poole, K.2
Nikaido, H.3
-
30
-
-
43749121852
-
SnB version 2.3: Triplet sieve phasing for centrosymmetric structures
-
Xu, H., Smith, A. B., Sahinidis, N. V. & Weeks, C. M. SnB version 2. 3: triplet sieve phasing for centrosymmetric structures. J. Appl. Cryst. 41, 644-646 (2008).
-
(2008)
J. Appl. Cryst.
, vol.41
, pp. 644-646
-
-
Xu, H.1
Smith, A.B.2
Sahinidis, N.V.3
Weeks, C.M.4
-
31
-
-
36549027357
-
Automated structure solution with autoSHARP
-
Vonrhein, C., Blanc, E., Roversi, P. & Bricogne, G. Automated structure solution with autoSHARP. Methods Mol. Biol. 364, 215-230 (2007).
-
(2007)
Methods Mol. Biol.
, vol.364
, pp. 215-230
-
-
Vonrhein, C.1
Blanc, E.2
Roversi, P.3
Bricogne, G.4
-
32
-
-
48849113878
-
Comparative protein structure modeling using MODELLER
-
Eswar, N. et al. Comparative protein structure modeling using MODELLER. Curr. Protoc. Protein Sci. 2, 2. 9. 1-2. 9. 31 (2007).
-
(2007)
Curr. Protoc. Protein Sci.
, vol.2
, pp. 291-2931
-
-
Eswar, N.1
-
33
-
-
13244281317
-
Coot: Model-building tools for molecular graphics
-
Emsley, P. & Cowtan, K. Coot: model-building tools for molecular graphics. Acta Crystallogr. D 60, 2126-2132 (2004).
-
(2004)
Acta Crystallogr. D
, vol.60
, pp. 2126-2132
-
-
Emsley, P.1
Cowtan, K.2
-
34
-
-
77949535720
-
Features and development of Coot
-
Emsley, P., Lohkamp, B., Scott, W. G. & Cowtan, K. Features and development of Coot. Acta Crystallogr. D 66, 486-501 (2010).
-
(2010)
Acta Crystallogr. D
, vol.66
, pp. 486-501
-
-
Emsley, P.1
Lohkamp, B.2
Scott, W.G.3
Cowtan, K.4
-
35
-
-
76449098262
-
PHENIX: A comprehensive Python-based system for macromolecular structure solution
-
Adams, P. D. et al. PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr. D 66, 213-221 (2010).
-
(2010)
Acta Crystallogr. D
, vol.66
, pp. 213-221
-
-
Adams, P.D.1
-
36
-
-
84860287260
-
Exploiting structure similarityin refinement: Automated NCS and target-structure restraints in BUSTER
-
Smart, O. S. et al. Exploiting structure similarityin refinement: automated NCS and target-structure restraints in BUSTER. Acta Crystallogr. D 68, 368-380 (2012).
-
(2012)
Acta Crystallogr. D
, vol.68
, pp. 368-380
-
-
Smart, O.S.1
-
37
-
-
74549178560
-
Mol Probity: All-atom structure validation for macromolecular crystallography
-
Chen, V. B. et al. Mol Probity: all-atom structure validation for macromolecular crystallography. Acta Crystallogr. D 66, 12-21 (2010).
-
(2010)
Acta Crystallogr. D
, vol.66
, pp. 12-21
-
-
Chen, V.B.1
-
38
-
-
34447508216
-
Phaser crystallographic software
-
McCoy, A. J. et al. Phaser crystallographic software. J. Appl. Cryst. 40, 658-674 (2007).
-
(2007)
J. Appl. Cryst.
, vol.40
, pp. 658-674
-
-
McCoy, A.J.1
-
39
-
-
49649085631
-
Automated structure solution with the PHENIX suite
-
Zwart, P. H. et al. Automated structure solution with the PHENIX suite. Methods Mol. Biol. 426, 419-435 (2008).
-
(2008)
Methods Mol. Biol.
, vol.426
, pp. 419-435
-
-
Zwart, P.H.1
-
40
-
-
0029975504
-
Conserved motifs in prokaryotic and eukaryotic polypeptide release factors: TRNA-protein mimicry hypothesis
-
Ito, K., Ebihara, K., Uno, M. & Nakamura, Y. Conserved motifs in prokaryotic and eukaryotic polypeptide release factors: tRNA-protein mimicry hypothesis. Proc. Natl Acad. Sci. USA 93, 5443-5448 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 5443-5448
-
-
Ito, K.1
Ebihara, K.2
Uno, M.3
Nakamura, Y.4
-
41
-
-
0000574498
-
Pressure-sensitive ion channel in Escherichia coli
-
Martinac, B., Buechner, M., Delcour, A. H., Adler, J. & Kung, C. Pressure-sensitive ion channel in Escherichia coli. Proc. Natl Acad. Sci. USA 84, 2297-2301 (1987).
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.84
, pp. 2297-2301
-
-
Martinac, B.1
Buechner, M.2
Delcour, A.H.3
Adler, J.4
Kung, C.5
|