Direct interaction of multidrug efflux transporter AcrB and outer membrane channel TolC detected via site-directed disulfide cross-linking

Biochemistry

Volumn 44, Issue 33, 2005, Pages 11115-11121

  Tamura, Norihisa ^a,b   Murakami, Satoshi ^a,b   Oyama, Yoshiaki ^c   Ishiguro, Masaji ^d   Yamaguchi, Akihito ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c SUNTORY LTD   (Japan)

^d SUNTORY INSTITUTE FOR BIOORGANIC RESEARCH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CROSSLINKING; ESCHERICHIA COLI; MEMBRANES; PROTONS; TOXIC MATERIALS;

COILED COILS; DRUG TOLERANCE; EFFLUX TRANSPORTER; VERTICAL HAIRPINS;

DRUG DOSAGE;

ACRB PROTEIN; CARRIER PROTEIN; CYSTEINE; MEMBRANE PROTEIN; MUTANT PROTEIN; POLYHISTIDINE; TOLC PROTEIN; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL OUTER MEMBRANE; BINDING SITE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISULFIDE BOND; DRUG TOLERANCE; DRUG TRANSPORT; ESCHERICHIA COLI; MEMBRANE CHANNEL; MOLECULAR CLONING; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

AMINO ACID SUBSTITUTION; BACTERIAL OUTER MEMBRANE PROTEINS; CARRIER PROTEINS; CELL MEMBRANE; CYSTEINE; DISULFIDES; DRUG TOLERANCE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION; HISTIDINE; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MULTIPROTEIN COMPLEXES; POINT MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY;

ESCHERICHIA COLI; RUMEX;

EID: 23944509010     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050452u     Document Type: Article

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