Structural basis for the inhibition of bacterial multidrug exporters

Nature

Volumn 500, Issue 7460, 2013, Pages 102-106

  Nakashima, Ryosuke ^a   Sakurai, Keisuke ^a   Yamasaki, Seiji ^a   Hayashi, Katsuhiko ^a   Nagata, Chikahiro ^b   Hoshino, Kazuki ^b   Onodera, Yoshikuni ^b   Nishino, Kunihiko ^a   Yamaguchi, Akihito ^a  

^a OSAKA UNIVERSITY   (Japan)

^b DAIICHI SANKYO CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; MEMBRANE PROTEIN; MINOCYCLINE; PHENYLALANINE; PROTEIN ACRB; PROTEIN MEXB; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBIOTICS; BACTERIUM; CRYSTAL STRUCTURE; INHIBITION; PATHOGEN;

ARTICLE; BINDING KINETICS; CONTROLLED STUDY; DRUG PROTEIN BINDING; HYDROPHOBICITY; INHIBITION KINETICS; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; PSEUDOMONAS AERUGINOSA;

ANTI-BACTERIAL AGENTS; BACTERIAL OUTER MEMBRANE PROTEINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MEMBRANE TRANSPORT PROTEINS; MODELS, MOLECULAR; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PROTEIN MULTIMERIZATION; PSEUDOMONAS AERUGINOSA; PYRIDINES; PYRIMIDINES; PYRIMIDINONES; ROTATION;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; PSEUDOMONAS AERUGINOSA;

EID: 84881474318     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature12300     Document Type: Article

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