-
1
-
-
85163545088
-
-
Academic, London
-
Holland, I. B., Cole, S. P. C., Kuchler, K. & Higgins, C. F. ABC Proteins: From Bacteria to Man (Academic, London, 2003).
-
(2003)
ABC Proteins: From Bacteria to Man
-
-
Holland, I.B.1
Cole, S.P.C.2
Kuchler, K.3
Higgins, C.F.4
-
2
-
-
0035682189
-
Overview: ABC transporters and human disease
-
Gottesman, M. M. & Ambudkar, S. V. Overview: ABC transporters and human disease. J. Bioenerg. Biomembr. 33, 453-458 (2001).
-
(2001)
J. Bioenerg. Biomembr.
, vol.33
, pp. 453-458
-
-
Gottesman, M.M.1
Ambudkar, S.V.2
-
3
-
-
0032912589
-
Structure and function of the CFTR chloride channel
-
Sheppard, D. N. & Welsh, M. J. Structure and function of the CFTR chloride channel. Physiol. Rev. 79, S23-S45 (1999).
-
(1999)
Physiol. Rev.
, vol.79
-
-
Sheppard, D.N.1
Welsh, M.J.2
-
4
-
-
0036080131
-
The transporter associated with antigen processing: Function and implications in human diseases
-
Lankat-Buttgereit, B. & Tampe, R. The transporter associated with antigen processing: function and implications in human diseases. Physiol. Rev. 82, 187-204 (2002).
-
(2002)
Physiol. Rev.
, vol.82
, pp. 187-204
-
-
Lankat-Buttgereit, B.1
Tampe, R.2
-
5
-
-
0032518394
-
A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene
-
van Veen, H.W. et al. A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene. Nature 391, 291-295 (1998).
-
(1998)
Nature
, vol.391
, pp. 291-295
-
-
Van Veen, H.W.1
-
6
-
-
0032698874
-
ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humans
-
Holland, I. B. & Blight, M. A. ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humans. J. Mol. Biol. 293, 381-399 (1999).
-
(1999)
J. Mol. Biol.
, vol.293
, pp. 381-399
-
-
Holland, I.B.1
Blight, M.A.2
-
7
-
-
0031810816
-
ATP-binding-cassette (ABC) transport systems: Functional and structural aspects of the ATP-hydrolyzing subunits/domains
-
Schneider, E. & Hunke, S. ATP-binding-cassette (ABC) transport systems: functional and structural aspects of the ATP-hydrolyzing subunits/domains. FEMS Microbiol. Rev. 22, 1-20 (1998).
-
(1998)
FEMS Microbiol. Rev.
, vol.22
, pp. 1-20
-
-
Schneider, E.1
Hunke, S.2
-
8
-
-
0029061103
-
Reconstitution of drug transport by purified P-glycoprotein
-
Shapiro, A. B. & Ling, V. Reconstitution of drug transport by purified P-glycoprotein. J. Biol. Chem. 270, 16167-16175 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 16167-16175
-
-
Shapiro, A.B.1
Ling, V.2
-
9
-
-
0034212332
-
The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism
-
van Veen, H. W., Margolles, A., Muller, M., Higgins, C. F. & Konings, W. N. The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism. EMBO J. 19, 2503-2514 (2000).
-
(2000)
EMBO J
, vol.19
, pp. 2503-2514
-
-
Van Veen, H.W.1
Margolles, A.2
Muller, M.3
Higgins, C.F.4
Konings, W.N.5
-
10
-
-
13244292479
-
Three-dimensional structure of P-glycoprotein-the transmembrane regions adopt an asymmetric configuration in the nucleotide-bound state
-
Rosenberg, M. F., Callaghan, R., Modok, S., Higgins, C. F. & Ford, R. C. Three-dimensional structure of P-glycoprotein-the transmembrane regions adopt an asymmetric configuration in the nucleotide-bound state. J. Biol. Chem. 280, 2857-2862 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 2857-2862
-
-
Rosenberg, M.F.1
Callaghan, R.2
Modok, S.3
Higgins, C.F.4
Ford, R.C.5
-
11
-
-
0037131184
-
Projection structure of P-glycoprotein by electron microscopy-evidence for a closed conformation of the nucleotide binding domains
-
Lee, J. Y., Urbatsch, I. L., Senior, A. E. & Wilkens, S. Projection structure of P-glycoprotein by electron microscopy-evidence for a closed conformation of the nucleotide binding domains. J. Biol. Chem. 277, 40125-40131 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 40125-40131
-
-
Lee, J.Y.1
Urbatsch, I.L.2
Senior, A.E.3
Wilkens, S.4
-
12
-
-
0035801375
-
Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing
-
Gaudet, R. & Wiley, D. C. Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing. EMBO J. 20, 4964-4972 (2001).
-
(2001)
EMBO J
, vol.20
, pp. 4964-4972
-
-
Gaudet, R.1
Wiley, D.C.2
-
13
-
-
0034705293
-
Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily
-
Hopfner, K. P. et al. Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily. Cell 101, 789-800 (2000).
-
(2000)
Cell
, vol.101
, pp. 789-800
-
-
Hopfner, K.P.1
-
14
-
-
0036342413
-
ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer
-
Smith, P. C. et al. ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer. Mol. Cell 10, 139-149 (2002).
-
(2002)
Mol. Cell
, vol.10
, pp. 139-149
-
-
Smith, P.C.1
-
15
-
-
0032479280
-
Mechanism of action of human P-glycoprotein ATPase activity-photochemical cleavage during a catalytic transition state using orthovanadate reveals cross-talk between the two ATP sites
-
Hrycyna, C. A. et al. Mechanism of action of human P-glycoprotein ATPase activity-photochemical cleavage during a catalytic transition state using orthovanadate reveals cross-talk between the two ATP sites. J. Biol. Chem. 273, 16631-16634 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16631-16634
-
-
Hrycyna, C.A.1
-
16
-
-
0035852667
-
Trapping the transition state of an ATP-binding cassette transporter: Evidence for a concerted mechanism of maltose transport
-
Chen, J., Sharma, S., Quiocho, F. A. & Davidson, A. L. Trapping the transition state of an ATP-binding cassette transporter: evidence for a concerted mechanism of maltose transport. Proc. Natl Acad. Sci. USA 98, 1525-1530 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 1525-1530
-
-
Chen, J.1
Sharma, S.2
Quiocho, F.A.3
Davidson, A.L.4
-
17
-
-
14544300522
-
CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains
-
Vergani, P., Lockless, S. W., Nairn, A. C. & Gadsby, D. C. CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains. Nature 433, 876-880 (2005).
-
(2005)
Nature
, vol.433
, pp. 876-880
-
-
Vergani, P.1
Lockless, S.W.2
Nairn, A.C.3
Gadsby, D.C.4
-
18
-
-
0032548468
-
P-glycoprotein shows strong catalytic cooperativity between the two nucleotide sites
-
Senior, A. E. & Bhagat, S. P-glycoprotein shows strong catalytic cooperativity between the two nucleotide sites. Biochemistry 37, 831-836 (1998).
-
(1998)
Biochemistry
, vol.37
, pp. 831-836
-
-
Senior, A.E.1
Bhagat, S.2
-
19
-
-
0037052565
-
The E. coli BtuCD structure: A framework for ABC transporter architecture and mechanism
-
Locher, K. P., Lee, A. T. & Rees, D. C. The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism. Science 296, 1091-1098 (2002).
-
(2002)
Science
, vol.296
, pp. 1091-1098
-
-
Locher, K.P.1
Lee, A.T.2
Rees, D.C.3
-
20
-
-
0042430573
-
Glycerol facilitator GlpF and the associated aquaporin family of channels
-
Stroud, R. M. et al. Glycerol facilitator GlpF and the associated aquaporin family of channels. Curr. Opin. Struct. Biol. 13, 424-431 (2003).
-
(2003)
Curr. Opin. Struct. Biol.
, vol.13
, pp. 424-431
-
-
Stroud, R.M.1
-
21
-
-
4143061717
-
Structural comparison of lactose permease and the glycerol-3-phosphate antiporter: Members of the major facilitator superfamily
-
Abramson, J., Kaback, H. R. & Iwata, S. Structural comparison of lactose permease and the glycerol-3-phosphate antiporter: members of the major facilitator superfamily. Curr. Opin. Struct. Biol. 14, 413-419 (2004).
-
(2004)
Curr. Opin. Struct. Biol.
, vol.14
, pp. 413-419
-
-
Abramson, J.1
Kaback, H.R.2
Iwata, S.3
-
22
-
-
0642272487
-
An atomic detail model for the human ATP binding cassette transporter P-glycoprotein derived from disulphide cross-linking and homology modeling
-
Stenham, D. R. et al. An atomic detail model for the human ATP binding cassette transporter P-glycoprotein derived from disulphide cross-linking and homology modeling. FASEB J. 17, 2287-2289 (2003).
-
(2003)
FASEB J
, vol.17
, pp. 2287-2289
-
-
Stenham, D.R.1
-
23
-
-
0035823075
-
Structure of MsbA from E. coli: A homolog of the multidrug resistance ATP binding cassette (ABC) transporters
-
Chang, G. & Roth, C. B. Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters. Science 293, 1793-1800 (2001).
-
(2001)
Science
, vol.293
, pp. 1793-1800
-
-
Chang, G.1
Roth, C.B.2
-
24
-
-
0038799725
-
Structure of MsbA from Vibrio cholera: A multidrug resistance ABC transporter homolog in a closed conformation
-
Chang, G. Structure of MsbA from Vibrio cholera: a multidrug resistance ABC transporter homolog in a closed conformation. J. Mol. Biol. 330, 419-430 (2003).
-
(2003)
J. Mol. Biol.
, vol.330
, pp. 419-430
-
-
Chang, G.1
-
25
-
-
18644363550
-
Structure of the ABC transporter MsbA in complex with ADP-vanadate and lipopolysaccharide
-
Reyes, C. L. & Chang, G. Structure of the ABC transporter MsbA in complex with ADP-vanadate and lipopolysaccharide. Science 308, 1028-1031 (2005).
-
(2005)
Science
, vol.308
, pp. 1028-1031
-
-
Reyes, C.L.1
Chang, G.2
-
26
-
-
0026473238
-
Identification of residues in the first cytoplasmic loop of P-glycoprotein involved in the function of chimeric human MDR1-MDR2 transporters
-
Currier, S. J. et al. Identification of residues in the first cytoplasmic loop of P-glycoprotein involved in the function of chimeric human MDR1-MDR2 transporters. J. Biol. Chem. 267, 25153-25159 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 25153-25159
-
-
Currier, S.J.1
-
27
-
-
0029835571
-
Effect of cystic fibrosis-associated mutations in the fourth intracellular loop of cystic fibrosis transmembrane conductance regulator
-
Cotten, J. F., Ostedgaard, L. S., Carson, M. R. & Welsh, M. J. Effect of cystic fibrosis-associated mutations in the fourth intracellular loop of cystic fibrosis transmembrane conductance regulator. J. Biol. Chem. 271, 21279-21284 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 21279-21284
-
-
Cotten, J.F.1
Ostedgaard, L.S.2
Carson, M.R.3
Welsh, M.J.4
-
28
-
-
0036108484
-
3D domain swapping: As domains continue to swap
-
Liu, Y. & Eisenberg, D. 3D domain swapping: as domains continue to swap. Protein Sci. 11, 1285-1299 (2002).
-
(2002)
Protein Sci.
, vol.11
, pp. 1285-1299
-
-
Liu, Y.1
Eisenberg, D.2
-
29
-
-
17944370228
-
Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle
-
Rosenberg, M. F. et al. Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle. EMBO J. 20, 5615-5625 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 5615-5625
-
-
Rosenberg, M.F.1
-
30
-
-
0032492724
-
Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state
-
Ramachandra, M. et al. Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state. Biochemistry 37, 5010-5019 (1998).
-
(1998)
Biochemistry
, vol.37
, pp. 5010-5019
-
-
Ramachandra, M.1
-
32
-
-
32044453808
-
Recent progress in understanding the mechanism of P-glycoprotein-mediated drug efflux
-
Loo, T. W. & Clarke, D. M. Recent progress in understanding the mechanism of P-glycoprotein-mediated drug efflux. J. Membr. Biol. 206, 173-185 (2005).
-
(2005)
J. Membr. Biol.
, vol.206
, pp. 173-185
-
-
Loo, T.W.1
Clarke, D.M.2
-
33
-
-
0030589291
-
Multiple regions of the transporter associated with antigen processing (TAP) contribute to its peptide binding site
-
Nijenhuis, M. & Hammerling, G. J. Multiple regions of the transporter associated with antigen processing (TAP) contribute to its peptide binding site. J. Immunol. 157, 5467-5477 (1996).
-
(1996)
J. Immunol.
, vol.157
, pp. 5467-5477
-
-
Nijenhuis, M.1
Hammerling, G.J.2
-
34
-
-
0014029736
-
Simple allosteric model for membrane pumps
-
Jardetzky, O. Simple allosteric model for membrane pumps. Nature 211, 969-970 (1966).
-
(1966)
Nature
, vol.211
, pp. 969-970
-
-
Jardetzky, O.1
-
35
-
-
0041529863
-
The ATP/substrate stoichiometry of the ATP-binding cassette (ABC) transporter OpuA
-
Patzlaff, J. S., van der Heide, T. & Poolman, B. The ATP/substrate stoichiometry of the ATP-binding cassette (ABC) transporter OpuA. J. Biol. Chem. 278, 29546-29551 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 29546-29551
-
-
Patzlaff, J.S.1
Van Der Heide, T.2
Poolman, B.3
-
36
-
-
0034646468
-
Evidence for a requirement for ATP hydrolysis at two distinct steps during a single turnover of the catalytic cycle of human P-glycoprotein
-
Sauna, Z. E. & Ambudkar, S. V. Evidence for a requirement for ATP hydrolysis at two distinct steps during a single turnover of the catalytic cycle of human P-glycoprotein. Proc. Natl Acad. Sci. USA 97, 2515-2520 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2515-2520
-
-
Sauna, Z.E.1
Ambudkar, S.V.2
-
37
-
-
0030782511
-
Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities
-
Shapiro, A. B. & Ling, V. Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities. Eur. J. Biochem. 250, 130-137 (1997).
-
(1997)
Eur. J. Biochem.
, vol.250
, pp. 130-137
-
-
Shapiro, A.B.1
Ling, V.2
-
38
-
-
0037666795
-
Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2)
-
Zelcer, N. et al. Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2). J. Biol. Chem. 278, 23538-23544 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 23538-23544
-
-
Zelcer, N.1
-
39
-
-
0037077296
-
Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters
-
Moody, J. E., Millen, L., Binns, D., Hunt, J. F. & Thomas, P. J. Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters. J. Biol. Chem. 277, 21111-21114 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21111-21114
-
-
Moody, J.E.1
Millen, L.2
Binns, D.3
Hunt, J.F.4
Thomas, P.J.5
-
40
-
-
0141527345
-
A tweezers-like motion of the ATP-binding cassette dimer in an ABC transport cycle
-
Chen, J., Lu, G., Lin, J., Davidson, A. L. & Quiocho, F. A. A tweezers-like motion of the ATP-binding cassette dimer in an ABC transport cycle. Mol. Cell 12, 651-661 (2003).
-
(2003)
Mol. Cell
, vol.12
, pp. 651-661
-
-
Chen, J.1
Lu, G.2
Lin, J.3
Davidson, A.L.4
Quiocho, F.A.5
-
41
-
-
27844520938
-
Crystallographic and single-particle analyses of native and nucleotide-bound forms of the cystic fibrosis transmembrane conductance regulator (CFTR) protein
-
Awayn, N. H. et al. Crystallographic and single-particle analyses of native and nucleotide-bound forms of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Biochem. Soc. Trans. 33, 996-999 (2005).
-
(2005)
Biochem. Soc. Trans.
, vol.33
, pp. 996-999
-
-
Awayn, N.H.1
-
42
-
-
0035853856
-
Demonstration of conformational changes associated with activation of the maltose transport complex
-
Mannering, D. E., Sharma, S. & Davidson, A. L. Demonstration of conformational changes associated with activation of the maltose transport complex. J. Biol. Chem. 276, 12362-12368 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12362-12368
-
-
Mannering, D.E.1
Sharma, S.2
Davidson, A.L.3
-
43
-
-
0025133518
-
Identification of mutations in regions corresponding to the two putative nucleotide (ATP)-binding folds of the cystic-fibrosis gene
-
Kerem, B. S. et al. Identification of mutations in regions corresponding to the two putative nucleotide (ATP)-binding folds of the cystic-fibrosis gene. Proc. Natl Acad. Sci. USA 87, 8447-8451 (1990).
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 8447-8451
-
-
Kerem, B.S.1
-
44
-
-
0026641782
-
The spectrum of cystic-fibrosis mutations
-
Tsui, L. C. The spectrum of cystic-fibrosis mutations. Trends Genet. 8, 392-398 (1992).
-
(1992)
Trends Genet.
, vol.8
, pp. 392-398
-
-
Tsui, L.C.1
-
45
-
-
19944432524
-
Impact of the ΔF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure
-
Lewis, H. A. et al. Impact of the ΔF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure. J. Biol. Chem. 280, 1346-1353 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 1346-1353
-
-
Lewis, H.A.1
|