Simulation of spontaneous substrate binding revealing the binding pathway and mechanism and initial conformational response of GlpT

Biochemistry

Volumn 49, Issue 6, 2010, Pages 1105-1114

  Enkavi, Giray ^a   Tajkhorshid, Emad ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONAL RESPONSE; DIRECT CONTACT; ELECTROSTATIC POTENTIALS; EQUILIBRIUM SIMULATIONS; INORGANIC PHOSPHATES; KEY BINDING; PHOSPHATE TRANSPORTERS; PSEUDOSYMMETRY; SALT BRIDGES; SUBSTRATE BINDING; SUBSTRATE-BOUND; SWITCH MECHANISM; WILD TYPES;

BINDING ENERGY; GLYCEROL; PHYSIOLOGICAL MODELS; PROTEINS;

SUBSTRATES;

CARRIER PROTEIN; GLYCEROL 3 PHOSPHATE TRANSPORT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; SIMULATION; STRUCTURE ANALYSIS;

ARGININE; BINDING SITES; CYTOPLASM; ESCHERICHIA COLI PROTEINS; HISTIDINE; MEMBRANE TRANSPORT PROTEINS; MEMBRANES, ARTIFICIAL; MOLECULAR DYNAMICS SIMULATION; MUTAGENESIS, SITE-DIRECTED; PERIPLASM; PHOSPHATIDYLETHANOLAMINES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TRANSPORT; STATIC ELECTRICITY; SUBSTRATE SPECIFICITY;

EID: 76749163994     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi901412a     Document Type: Article

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