-
1
-
-
0028314541
-
Multidrug resistance pumps in bacteria: Variations on a theme
-
Lewis, K. 1994. Multidrug resistance pumps in bacteria: variations on a theme. Trends Biochem. Sci. 19:119-123.
-
(1994)
Trends Biochem. Sci.
, vol.19
, pp. 119-123
-
-
Lewis, K.1
-
2
-
-
0029845913
-
Multidrug efflux pumps of Gram-negative bacteria
-
Nikaido, H. 1996. Multidrug efflux pumps of Gram-negative bacteria. J. Bacteriol. 178:5853-5859.
-
(1996)
J. Bacteriol.
, vol.178
, pp. 5853-5859
-
-
Nikaido, H.1
-
3
-
-
0027494050
-
Multiple antibiotic resistance in Pseudomonas aeruginosa: Evidence for involvement of an efflux operon
-
Poole, K., K. Krebes, C. McNally, and S. Neshat. 1993. Multiple antibiotic resistance in Pseudomonas aeruginosa: evidence for involvement of an efflux operon. J. Bacteriol. 175:7363-7372.
-
(1993)
J. Bacteriol.
, vol.175
, pp. 7363-7372
-
-
Poole, K.1
Krebes, K.2
McNally, C.3
Neshat, S.4
-
4
-
-
0029796966
-
Evidence that TolC is required for functioning of the mar/acrab efflux pump of Escherichia coli
-
Fralick, J. A. 1996. Evidence that TolC is required for functioning of the mar/acrab efflux pump of Escherichia coli. J. Bacteriol. 178:5803-5805.
-
(1996)
J. Bacteriol.
, vol.178
, pp. 5803-5805
-
-
Fralick, J.A.1
-
5
-
-
0035150225
-
Type I secretion and multidrug efflux: Transport through the TolC channel-tunnel
-
Buchanan, S. K. 2001. Type I secretion and multidrug efflux: transport through the TolC channel-tunnel. Trends Biochem. Sci. 26:3-6.
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 3-6
-
-
Buchanan, S.K.1
-
6
-
-
3943108216
-
Structure and function of TolC: The bacterial exit duct for proteins and drugs
-
Koronakis, V., J. Eswaran, and C. Hughes. 2004. Structure and function of TolC: the bacterial exit duct for proteins and drugs. Annu. Rev. Biochem. 73:467-489.
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 467-489
-
-
Koronakis, V.1
Eswaran, J.2
Hughes, C.3
-
7
-
-
9944247705
-
Three's company: Component structures bring a closer view of tripartite drug efflux pumps
-
Eswaran, J., E. Koronakis, M. K. Higgins, C. Hughes, and V. Koronakis. 2004. Three's company: component structures bring a closer view of tripartite drug efflux pumps. Curr. Opin. Struct. Biol. 14:717-747.
-
(2004)
Curr. Opin. Struct. Biol.
, vol.14
, pp. 717-747
-
-
Eswaran, J.1
Koronakis, E.2
Higgins, M.K.3
Hughes, C.4
Koronakis, V.5
-
8
-
-
0034702177
-
Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export
-
Koronakis, V., A. Sharff, E. Koronakis, B. Luisi, and C. Hughes. 2000. Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export. Nature. 405:914-919.
-
(2000)
Nature
, vol.405
, pp. 914-919
-
-
Koronakis, V.1
Sharff, A.2
Koronakis, E.3
Luisi, B.4
Hughes, C.5
-
9
-
-
0037057652
-
Crystal structure of bacterial multidrug efflux transporter AcrB
-
Murakami, S., R. Nakashima, E. Yamashita, and A. Yamaguchi. 2002. Crystal structure of bacterial multidrug efflux transporter AcrB. Nature. 419:587-593.
-
(2002)
Nature
, vol.419
, pp. 587-593
-
-
Murakami, S.1
Nakashima, R.2
Yamashita, E.3
Yamaguchi, A.4
-
10
-
-
11144222920
-
Crystal structure of the drug discharge outer membrane protein, OprM, of Pseudomonas aeruginosa: Dual modes of membrane anchoring and occluded cavity end
-
Akama, H., M. Kanemaki, T. Tsukihara, A. Nakagawa, and T. Nakae. 2004. Crystal structure of the drug discharge outer membrane protein, OprM, of Pseudomonas aeruginosa: dual modes of membrane anchoring and occluded cavity end. J. Biol. Chem. 279:52816-52819.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 52816-52819
-
-
Akama, H.1
Kanemaki, M.2
Tsukihara, T.3
Nakagawa, A.4
Nakae, T.5
-
11
-
-
17644392862
-
The crystal structure of the outer membrane protein VceC from the bacterial pathogen Vibrio cholerae at 1.8 Å resolution
-
Federici, L., D. Du, F. Walas, H. Matsumura, J. Fernandez-Recio, K. S. McKeegan, M. I. Borges-Walmsley, B. F. Luisi, and A. R. Walmsley. 2005. The crystal structure of the outer membrane protein VceC from the bacterial pathogen Vibrio cholerae at 1.8 Å resolution. J. Biol. Chem. 280:15307-15314.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 15307-15314
-
-
Federici, L.1
Du, D.2
Walas, F.3
Matsumura, H.4
Fernandez-Recio, J.5
McKeegan, K.S.6
Borges-Walmsley, M.I.7
Luisi, B.F.8
Walmsley, A.R.9
-
12
-
-
3042838743
-
The structure of the periplasmic component of a drug efflux pump
-
Higgins, M. K., E. Bokma, E. Koronakis, C. Hughes, and V. Koronakis. 2004. The structure of the periplasmic component of a drug efflux pump. Proc. Natl. Acad. Sci. USA. 101:9994-9999.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 9994-9999
-
-
Higgins, M.K.1
Bokma, E.2
Koronakis, E.3
Hughes, C.4
Koronakis, V.5
-
13
-
-
2942731519
-
Crystal structure of the membrane fusion protein, MexA, of the multidrug transporter in Pseudomonas aeruginosa
-
Akama, H., T. Matsuura, S. Kashiwagi, H. Yoneyama, T. Tsukihara, A. Nakagawa, and T. Nakae. 2004. Crystal structure of the membrane fusion protein, MexA, of the multidrug transporter in Pseudomonas aeruginosa. J. Biol. Chem. 279:25939-25942.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 25939-25942
-
-
Akama, H.1
Matsuura, T.2
Kashiwagi, S.3
Yoneyama, H.4
Tsukihara, T.5
Nakagawa, A.6
Nakae, T.7
-
14
-
-
33644833626
-
Conformational flexibility in the multidrug efflux system protein AcrA
-
Mikolosko, J., K. Bobyk, H. I. Zgurskaya, and P. Ghosh. 2006. Conformational flexibility in the multidrug efflux system protein AcrA. Structure. 14:577-587.
-
(2006)
Structure
, vol.14
, pp. 577-587
-
-
Mikolosko, J.1
Bobyk, K.2
Zgurskaya, H.I.3
Ghosh, P.4
-
15
-
-
0033515434
-
Alignment and structure prediction of divergent protein families: Periplasmic and outer membrane proteins of bacterial efflux pumps
-
Johnson, J. M., and G. M. Church. 1999. Alignment and structure prediction of divergent protein families: periplasmic and outer membrane proteins of bacterial efflux pumps. J. Mol. Biol. 287:695-715.
-
(1999)
J. Mol. Biol.
, vol.287
, pp. 695-715
-
-
Johnson, J.M.1
Church, G.M.2
-
16
-
-
0033534373
-
AcrA is a highly asymmetric protein capable of spanning the periplasm
-
Zgurskaya, H. I., and H. Nikaido. 1999. AcrA is a highly asymmetric protein capable of spanning the periplasm. J. Mol. Biol. 285:409-420.
-
(1999)
J. Mol. Biol.
, vol.285
, pp. 409-420
-
-
Zgurskaya, H.I.1
Nikaido, H.2
-
17
-
-
3242890387
-
Interactions underlying assembly of the Escherichia coli AcrAB-TolC multidrug efflux system
-
Touzé, T., J. Eswaran, E. Bokma, E. Koronakis, C. Hughes, and V. Koronakis. 2004. Interactions underlying assembly of the Escherichia coli AcrAB-TolC multidrug efflux system. Mol. Microbiol. 53:697-706.
-
(2004)
Mol. Microbiol.
, vol.53
, pp. 697-706
-
-
Touzé, T.1
Eswaran, J.2
Bokma, E.3
Koronakis, E.4
Hughes, C.5
Koronakis, V.6
-
18
-
-
0042838181
-
Chimeric analysis of AcrA function reveals the importance of its C-terminal domain in its interaction with the AcrB multidrug efflux pump
-
Elkins, C. A., and H. Nikaido. 2003. Chimeric analysis of AcrA function reveals the importance of its C-terminal domain in its interaction with the AcrB multidrug efflux pump. J. Bacteriol. 185:5349-5356.
-
(2003)
J. Bacteriol.
, vol.185
, pp. 5349-5356
-
-
Elkins, C.A.1
Nikaido, H.2
-
19
-
-
2342664171
-
Assembly of the MexAB-OprM multidrug efflux system of Pseudomonas aeruginosa: Identification and characterization of mutations in MexA compromising MexA multimerization and interaction with MexB
-
Nehme, D., X. Li, R. Elliot, and K. Poole. 2004. Assembly of the MexAB-OprM multidrug efflux system of Pseudomonas aeruginosa: identification and characterization of mutations in MexA compromising MexA multimerization and interaction with MexB. J. Bacteriol. 186:2973-2983.
-
(2004)
J. Bacteriol.
, vol.186
, pp. 2973-2983
-
-
Nehme, D.1
Li, X.2
Elliot, R.3
Poole, K.4
-
20
-
-
9644281653
-
A model of a transmembrane drug-efflux pump from Gram-negative bacteria
-
Fernandez-Recio, J., F. Walas, L. Federici, J. Venkatesh Patrap, V. N. Bavro, R. Nunez Miguel, K. Mizuguchi, and B. Luisi. 2004. A model of a transmembrane drug-efflux pump from Gram-negative bacteria. FEBS Lett. 578:5-9.
-
(2004)
FEBS Lett.
, vol.578
, pp. 5-9
-
-
Fernandez-Recio, J.1
Walas, F.2
Federici, L.3
Venkatesh Patrap, J.4
Bavro, V.N.5
Nunez Miguel, R.6
Mizuguchi, K.7
Luisi, B.8
-
21
-
-
0036725277
-
Molecular dynamics simulations of biomolecules
-
Karplus, M. J., and J. A. McCammon. 2002. Molecular dynamics simulations of biomolecules. Nat. Struct. Biol. 9:646-652.
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 646-652
-
-
Karplus, M.J.1
McCammon, J.A.2
-
22
-
-
0036721233
-
Normal mode analysis of macromolecular motions in a database framework
-
Krebs, W. G., V. Alexandrov, C. A. Wilson, N. Echols, H. Yu, and M. Gerstein. 2002. Normal mode analysis of macromolecular motions in a database framework. Proteins. 48:682-695.
-
(2002)
Proteins
, vol.48
, pp. 682-695
-
-
Krebs, W.G.1
Alexandrov, V.2
Wilson, C.A.3
Echols, N.4
Yu, H.5
Gerstein, M.6
-
23
-
-
0025398721
-
WhatIf - A molecular modeling and drug design program
-
Vriend, G. 1990. WhatIf - a molecular modeling and drug design program. J. Mol. Graph. 8:52-56.
-
(1990)
J. Mol. Graph.
, vol.8
, pp. 52-56
-
-
Vriend, G.1
-
24
-
-
0035789518
-
GROMACS 3.0: A package for molecular simulation and trajectory analysis
-
Lindahl, E., B. Hess, and D. van der Spoel. 2001. GROMACS 3.0: a package for molecular simulation and trajectory analysis. J. Mol. Model. (Online). 7:306-317.
-
(2001)
J. Mol. Model. (Online)
, vol.7
, pp. 306-317
-
-
Lindahl, E.1
Hess, B.2
Van Der Spoel, D.3
-
25
-
-
0000388705
-
LINCS: A linear constraint solver for molecular simulations
-
Hess, B., H. Bekker, H. J. C. Berendsen, and J. G. E. M. Fraaije. 1997. LINCS: a linear constraint solver for molecular simulations. J. Comput. Chem. 18:1463-1472.
-
(1997)
J. Comput. Chem.
, vol.18
, pp. 1463-1472
-
-
Hess, B.1
Bekker, H.2
Berendsen, H.J.C.3
Fraaije, J.G.E.M.4
-
26
-
-
33846823909
-
Particle mesh Ewald - An N.log(N) method for Ewald sums in large systems
-
Darden, T., D. York, and L. Pedersen. 1993. Particle mesh Ewald - an N.log(N) method for Ewald sums in large systems. J. Chem. Phys. 98:10089-10092.
-
(1993)
J. Chem. Phys.
, vol.98
, pp. 10089-10092
-
-
Darden, T.1
York, D.2
Pedersen, L.3
-
27
-
-
33645961739
-
A smooth particle mesh Ewald method
-
Essmann, U., L. Perera, M. L. Berkowitz, T. Darden, H. Lee, and L. G. Pedersen. 1995. A smooth particle mesh Ewald method. J. Chem. Phys. 103:8577-8593.
-
(1995)
J. Chem. Phys.
, vol.103
, pp. 8577-8593
-
-
Essmann, U.1
Perera, L.2
Berkowitz, M.L.3
Darden, T.4
Lee, H.5
Pedersen, L.G.6
-
28
-
-
33750587438
-
Molecular dynamics with coupling to an external bath
-
Berendsen, H. J. C., J. P. M. Postma, W. F. van Gunsteren, A. DiNola, and J. R. Haak. 1984. Molecular dynamics with coupling to an external bath. J. Chem. Phys. 81:3684-3690.
-
(1984)
J. Chem. Phys.
, vol.81
, pp. 3684-3690
-
-
Berendsen, H.J.C.1
Postma, J.P.M.2
Van Gunsteren, W.F.3
DiNola, A.4
Haak, J.R.5
-
29
-
-
0020997912
-
Dictionary of protein secondary structure: Pattern-recognition of hydrogen-bonded and geometrical features
-
Kabsch, W., and C. Sander. 1983. Dictionary of protein secondary structure: pattern-recognition of hydrogen-bonded and geometrical features. Biopolymers. 22:2577-2637.
-
(1983)
Biopolymers
, vol.22
, pp. 2577-2637
-
-
Kabsch, W.1
Sander, C.2
-
30
-
-
16644370327
-
Dynamite: A simple way to gain insight into protein motions
-
Barrett, C. P., B. A. Hall, and M. E. M. Noble. 2004. Dynamite: a simple way to gain insight into protein motions. Acta Crystallogr. D. 60:2280-2287.
-
(2004)
Acta Crystallogr. D.
, vol.60
, pp. 2280-2287
-
-
Barrett, C.P.1
Hall, B.A.2
Noble, M.E.M.3
-
33
-
-
0000577041
-
Large-amplitude nonlinear motions in proteins
-
Garcia, A. E. 1992. Large-amplitude nonlinear motions in proteins. Phys. Rev. Lett. 68:2696-2699.
-
(1992)
Phys. Rev. Lett.
, vol.68
, pp. 2696-2699
-
-
Garcia, A.E.1
-
34
-
-
0034906622
-
Analysis of a 10-ns molecular dynamics simulation of mouse acetylcholinesterase
-
Tai, K., T. Shen, U. Börjesson, M. Philippopoulos, and J. A. McCammon. 2001. Analysis of a 10-ns molecular dynamics simulation of mouse acetylcholinesterase. Biophys. J. 81:715-724.
-
(2001)
Biophys. J.
, vol.81
, pp. 715-724
-
-
Tai, K.1
Shen, T.2
Börjesson, U.3
Philippopoulos, M.4
McCammon, J.A.5
-
35
-
-
0346749468
-
pH-induced conformational changes of AcrA, the membrane fusion protein of Escherichia coli multidrug efflux system
-
Ip, H., K. Stratton, H. Zgurskaya, and J. Liu. 2003. pH-induced conformational changes of AcrA, the membrane fusion protein of Escherichia coli multidrug efflux system. J. Biol. Chem. 278:50474-50482.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 50474-50482
-
-
Ip, H.1
Stratton, K.2
Zgurskaya, H.3
Liu, J.4
-
36
-
-
0037143615
-
Transition to the open state of the TolC periplasmic tunnel entrance
-
Andersen, C., E. Koronakis, E. Bokma, J. Eswaran, D. Humphreys, C. Hughes, and V. Koronakis. 2002. Transition to the open state of the TolC periplasmic tunnel entrance. Proc. Natl. Acad. Sci. USA. 99:11103-11108.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 11103-11108
-
-
Andersen, C.1
Koronakis, E.2
Bokma, E.3
Eswaran, J.4
Humphreys, D.5
Hughes, C.6
Koronakis, V.7
-
37
-
-
10344261477
-
Conformational sampling and dynamics of membrane proteins from 10-nanosecond computer simulations
-
Faraldo-Gómez, J. D., L. R. Forrest, M. Baaden, P. J. Bond, C. Domene, G. Patargias, J. Cuthbertson, and M. S. P. Sansom. 2004. Conformational sampling and dynamics of membrane proteins from 10-nanosecond computer simulations. Proteins. 57:783-791.
-
(2004)
Proteins
, vol.57
, pp. 783-791
-
-
Faraldo-Gómez, J.D.1
Forrest, L.R.2
Baaden, M.3
Bond, P.J.4
Domene, C.5
Patargias, G.6
Cuthbertson, J.7
Sansom, M.S.P.8
-
38
-
-
1342302339
-
Conformational changes associated with protein-protein interactions
-
Goh, C. S., D. Milburn, and M. Gerstein. 2004. Conformational changes associated with protein-protein interactions. Curr. Opin. Struct. Biol. 14:104-109.
-
(2004)
Curr. Opin. Struct. Biol.
, vol.14
, pp. 104-109
-
-
Goh, C.S.1
Milburn, D.2
Gerstein, M.3
|