Drug export pathway of multidrug exporter AcrB revealed by DARPin inhibitors

PLoS Biology

Volumn 5, Issue 1, 2007, Pages 0106-0113

  Sennhauser, Gaby ^a   Amstutz, Patrick ^a,b   Briand, Christophe ^a   Storchenegger, Otso ^a   Grütter, Markus G ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b MOLECULAR PARTNERS AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANKYRIN; BACTERIAL PROTEIN; DARP INHIBITOR; GLYCOPROTEIN P; MULTIDRUG EXPORTER ACRB PROTEIN; UNCLASSIFIED DRUG; ACRE PROTEIN, E COLI; ESCHERICHIA COLI PROTEIN; MULTIDRUG RESISTANCE PROTEIN; MULTIPROTEIN COMPLEX; PROTEIN SUBUNIT;

ARTICLE; CELL MEMBRANE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG TRANSPORT; ESCHERICHIA COLI; LIGAND BINDING; NONHUMAN; PROTEIN BINDING; PROTEIN CONFORMATION; PROTON TRANSPORT; CHEMISTRY; DRUG ANTAGONISM; METABOLISM; MULTIDRUG RESISTANCE; PHYSIOLOGY; PROTEIN FOLDING; PROTON MOTIVE FORCE; SIGNAL TRANSDUCTION; TRANSPORT AT THE CELLULAR LEVEL; X RAY CRYSTALLOGRAPHY;

ESCHERICHIA COLI;

ANKYRIN REPEAT; BIOLOGICAL TRANSPORT; CRYSTALLOGRAPHY, X-RAY; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI PROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MULTIPROTEIN COMPLEXES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN SUBUNITS; PROTON-MOTIVE FORCE; SIGNAL TRANSDUCTION;

EID: 33846363597     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.0050007     Document Type: Article

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