Asymmetric switching in a homodimeric ABC transporter: A simulation study

PLoS Computational Biology

Volumn 6, Issue 4, 2010, Pages

  Aittoniemi, Jussi ^a   de Wet, Heidi ^a   Ashcroft, Frances M ^a   Sansom, Mark S P ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; BIOLOGICAL MEMBRANES; COMPUTER ARCHITECTURE; CRYSTAL STRUCTURE; DIMERS; ION EXCHANGE; MOLECULAR DYNAMICS; NUCLEOTIDES; PROTEINS;

ABC TRANSPORTER; ATP HYDROLYSIS; CELLULAR PROCESS; CHANNEL REGULATION; EUKARYOTICS; HOMODIMERICS; ION CHANNEL; MEMBRANE PROTEINS; NUCLEOTIDE-BINDING SITES; SIMULATION STUDIES;

HYDROLYSIS;

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; ASPARTIC ACID; GLUTAMINE; HISTIDINE; ION CHANNEL; MEMBRANE PROTEIN; BACTERIAL PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CHANNEL GATING; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; EUKARYOTE; HYDROLYSIS; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; MULTIDRUG RESISTANCE; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN FUNCTION; AMINO ACID SEQUENCE; CHEMISTRY; COMPUTER SIMULATION; GENETICS; LIPID METABOLISM; METABOLISM; MOLECULAR GENETICS; SEQUENCE ALIGNMENT;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL PROTEINS; BINDING SITES; COMPUTER SIMULATION; DRUG RESISTANCE, MULTIPLE, BACTERIAL; LIPID METABOLISM; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT;

EID: 77954613193     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000762     Document Type: Article

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