Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis

Journal of Cell Biology

Volumn 164, Issue 4, 2004, Pages 493-499

  Karbowski, Mariusz ^a   Arnoult, Damien ^a   Chen, Hsiuchen ^c   Chan, David C ^c   Smith, Carolyn L ^b   Youle, Richard J ^a,d  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^d NONE   (United States)

Author keywords

Dynamin; Fission; Opal; PAGFP; Photoactivation

Indexed keywords

CASPASE; CYTOCHROME C OXIDASE; GREEN FLUORESCENT PROTEIN; PROTEIN BAK; PROTEIN BAX; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SMALL INTERFERING RNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL FUSION; CELL PERMEABILIZATION; CELL STRAIN COS7; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVATION; EXPRESSION VECTOR; FIBROBLAST; GENETIC TRANSFECTION; HELA CELL; HIPPOCAMPUS; HUMAN; HUMAN CELL; MITOCHONDRION; MUSCLE CELL; NERVE CELL; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BIOLOGICAL ASSAY; CASPASES; CELLS, CULTURED; FIBROBLASTS; GREEN FLUORESCENT PROTEINS; HUMANS; LUMINESCENT PROTEINS; MEMBRANE FUSION; MICE; MICROSCOPY, CONFOCAL; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NEURONS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RECOMBINANT FUSION PROTEINS;

ANIMALIA;

EID: 1242307475     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200309082     Document Type: Article

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