Corrigendum to "Mechanisms, locations, and kinetics of synaptic BDNF secretion: An update" [Neurosci. Res. 65 (2009) 11-22] (DOI:10.1016/j.neures.2009.06.004);Mechanisms, locations, and kinetics of synaptic BDNF secretion: An update

Neuroscience Research

Volumn 65, Issue 1, 2009, Pages 11-22

  Leßmann, Volkmar ^a   Brigadski, Tanja ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Fusion pore; Neurotrophins; Peptide; Proneurotrophins; Release; Secretion; Sortilin; Synaptic plasticity

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; NERVE GROWTH FACTOR; NEUROTROPHIN 3; NEUROTROPHIN 4;

ARTICLE; DENDRITE; HUMAN; NERVE CELL PLASTICITY; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN SYNTHESIS; PROTEIN TARGETING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SYNAPSE VESICLE;

EID: 67650450676     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2009.08.006     Document Type: Erratum

References (115)

1. Adachi N., Kohara K., and Tsumoto T. Difference in trafficking of brain-derived neurotrophic factor between axons and dendrites of cortical neurons, revealed by live-cell imaging. BMC Neurosci. 6 (2005) 42
2. Aicardi G., Argilli E., Cappello S., Santi S., Riccio M., Thoenen H., and Canossa M. Induction of long-term potentiation and depression is reflected by corresponding changes in secretion of endogenous brain-derived neurotrophic factor. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 15788-15792
3. Altar C.A., and DiStefano P.S. Neurotrophin trafficking by anterograde transport. Trends Neurosci. 21 (1998) 433-437
4. Amaral M.D., and Pozzo-Miller L. BDNF induces calcium elevations associated with IBDNF, a nonselective cationic current mediated by TRPC channels. J. Neurophysiol. 98 (2007) 2476-2482
5. Amaral M.D., and Pozzo-Miller L. TRPC3 channels are necessary for brain-derived neurotrophic factor to activate a nonselective cationic current and to induce dendritic spine formation. J. Neurosci. 27 (2007) 5179-5189
6. Angleson J.K., Cochilla A.J., Kilic G., Nussinovitch I., and Betz W.J. Regulation of dense core release from neuroendocrine cells revealed by imaging single exocytic events. Nat. Neurosci. 2 (1999) 440-446
7. Bai L., Zhu D., Zhou K., Zhou W., Li D., Wang Y., Zhang R., and Xu T. Differential properties of GTP- and Ca(2+)-stimulated exocytosis from large dense core vesicles. Traffic 7 (2006) 416-428
8. Balkowiec A., and Katz D.M. Cellular mechanisms regulating activity-dependent release of native brain-derived neurotrophic factor from hippocampal neurons. J. Neurosci. 22 (2002) 10399-10407
9. Barg S., Olofsson C.S., Schriever-Abeln J., Wendt A., Gebre-Medhin S., Renstrom E., and Rorsman P. Delay between fusion pore opening and peptide release from large dense-core vesicles in neuroendocrine cells. Neuron 33 (2002) 287-299
10. Blum R., Kafitz K.W., and Konnerth A. Neurotrophin-evoked depolarization requires the sodium channel Na(V)1.9. Nature 419 (2002) 687-693
11. Bradshaw R.A., Brickey W.W., and Walker K.W. N-terminal processing: the methionine aminopeptidase and N alpha-acetyl transferase families. Trends Biochem. Sci. 23 (1998) 263-267
12. Bramham C.R., and Messaoudi E. BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis. Prog. Neurobiol. 76 (2005) 99-125
13. Brigadski T., Hartmann M., and Lessmann V. Differential vesicular targeting and time course of synaptic secretion of the mammalian neurotrophins. J. Neurosci. 25 (2005) 7601-7614
14. Bruno M.A., and Cuello A.C. Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade. Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 6735-6740
15. Burgoyne R.D., and Morgan A. Secretory granule exocytosis. Physiol. Rev. 83 (2003) 581-632
16. Caldeira M.V., Melo C.V., Pereira D.B., Carvalho R., Correia S.S., Backos D.S., Carvalho A.L., Esteban J.A., and Duarte C.B. Brain-derived neurotrophic factor regulates the expression and synaptic delivery of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits in hippocampal neurons. J. Biol. Chem. 282 (2007) 12619-12628
17. Carvalho A.L., Caldeira M.V., Santos S.D., and Duarte C.B. Role of the brain-derived neurotrophic factor at glutamatergic synapses. Br. J. Pharmacol. 153 Suppl. 1 (2008) S310-S324
18. Chanat E., and Huttner W.B. Milieu-induced, selective aggregation of regulated secretory proteins in the trans-Golgi network. J. Cell Biol. 115 (1991) 1505-1519
19. Chanat E., Pimplikar S.W., Stinchcombe J.C., and Huttner W.B. What the granins tell us about the formation of secretory granules in neuroendocrine cells. Cell Biophys. 19 (1991) 85-91
20. Chen Z.Y., Patel P.D., Sant G., Meng C.X., Teng K.K., Hempstead B.L., and Lee F.S. Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons. J. Neurosci. 24 (2004) 4401-4411
21. Chen Z.Y., Ieraci A., Teng H., Dall H., Meng C.X., Herrera D.G., Nykjaer A., Hempstead B.L., and Lee F.S. Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway. J. Neurosci. 25 (2005) 6156-6166
22. Conner J.M., Lauterborn J.C., Yan Q., Gall C.M., and Varon S. Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: evidence for anterograde axonal transport. J. Neurosci. 17 (1997) 2295-2313
23. Coull J.A., Beggs S., Boudreau D., Boivin D., Tsuda M., Inoue K., Gravel C., Salter M.W., and De K.Y. BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain. Nature 438 (2005) 1017-1021
24. Crozier R.A., Bi C., Han Y.R., and Plummer M.R. BDNF modulation of NMDA receptors is activity dependent. J. Neurophysiol. 100 (2008) 3264-3274
25. Danzer S.C., and McNamara J.O. Localization of brain-derived neurotrophic factor to distinct terminals of mossy fiber axons implies regulation of both excitation and feedforward inhibition of CA3 pyramidal cells. J. Neurosci. 24 (2004) 11346-11355
26. de Kock C.P., Burnashev N., Lodder J.C., Mansvelder H.D., and Brussaard A.B. NMDA receptors induce somatodendritic secretion in hypothalamic neurones of lactating female rats. J. Physiol. 561 (2004) 53-64
27. del Toro D., Canals J.M., Gines S., Kojima M., Egea G., and Alberch J. Mutant huntingtin impairs the post-Golgi trafficking of brain-derived neurotrophic factor but not its Val66Met polymorphism. J. Neurosci. 26 (2006) 12748-12757
28. de Wit J., Toonen R.F., Verhaagen J., and Verhage M. Vesicular trafficking of semaphorin 3A is activity-dependent and differs between axons and dendrites. Traffic 7 (2006) 1060-1077
29. Dicou E. Peptides other than the neurotrophins that can be cleaved from proneurotrophins: a neglected story. Arch. Physiol. Biochem. 113 (2007) 228-233
30. Dikeakos J.D., and Reudelhuber T.L. Sending proteins to dense core secretory granules: still a lot to sort out. J. Cell Biol. 177 (2007) 191-196
31. Egan M.F., Kojima M., Callicott J.H., Goldberg T.E., Kolachana B.S., Bertolino A., Zaitsev E., Gold B., Goldman D., Dean M., Lu B., and Weinberger D.R. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 112 (2003) 257-269
32. Eipper B.A., Stoffers D.A., and Mains R.E. The biosynthesis of neuropeptides: peptide alpha-amidation. Annu. Rev. Neurosci. 15 (1992) 57-85
33. Fahnestock M., Michalski B., Xu B., and Coughlin M.D. The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease. Mol. Cell Neurosci. 18 (2001) 210-220
34. Farhadi H.F., Mowla S.J., Petrecca K., Morris S.J., Seidah N.G., and Murphy R.A. Neurotrophin-3 sorts to the constitutive secretory pathway of hippocampal neurons and is diverted to the regulated secretory pathway by coexpression with brain-derived neurotrophic factor. J. Neurosci. 20 (2000) 4059-4068
35. Fayard B., Loeffler S., Weis J., Vogelin E., and Kruttgen A. The secreted brain-derived neurotrophic factor precursor pro-BDNF binds to TrkB and p75NTR but not to TrkA or TrkC. J. Neurosci. Res. 80 (2005) 18-28
36. Gartner A., Polnau D.G., Staiger V., Sciarretta C., Minichiello L., Thoenen H., Bonhoeffer T., and Korte M. Hippocampal long-term potentiation is supported by presynaptic and postsynaptic tyrosine receptor kinase B-mediated phospholipase Cgamma signaling. J. Neurosci. 26 (2006) 3496-3504
37. Gauthier L.R., Charrin B.C., Borrell-Pages M., Dompierre J.P., Rangone H., Cordelieres F.P., De M.J., MacDonald M.E., Lessmann V., Humbert S., and Saudou F. Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell 118 (2004) 127-138
38. Griesbeck O., Canossa M., Campana G., Gartner A., Hoener M.C., Nawa H., Kolbeck R., and Thoenen H. Are there differences between the secretion characteristics of NGF and BDNF? Implications for the modulatory role of neurotrophins in activity-dependent neuronal plasticity. Microsc. Res. Tech. 45 (1999) 262-275
39. Gubellini P., Ben-Ari Y., and Gaiarsa J.L. Endogenous neurotrophins are required for the induction of GABAergic long-term potentiation in the neonatal rat hippocampus. J. Neurosci. 25 (2005) 5796-5802
40. Han W., Li D., Stout A.K., Takimoto K., and Levitan E.S. Ca2+-induced deprotonation of peptide hormones inside secretory vesicles in preparation for release. J. Neurosci. 19 (1999) 900-905
41. Harata N.C., Choi S., Pyle J.L., Aravanis A.M., and Tsien R.W. Frequency-dependent kinetics and prevalence of kiss-and-run and reuse at hippocampal synapses studied with novel quenching methods. Neuron 49 (2006) 243-256
42. Hartmann M., Heumann R., and Lessmann V. Synaptic secretion of BDNF after high-frequency stimulation of glutamatergic synapses. EMBO J. 20 (2001) 5887-5897
43. Haubensak W., Narz F., Heumann R., and Lessmann V. BDNF-GFP containing secretory granules are localized in the vicinity of synaptic junctions of cultured cortical neurons. J. Cell Sci. 111 Pt. 11 (1998) 1483-1493
44. Heymach Jr. J.V., Kruttgen A., Suter U., and Shooter E.M. The regulated secretion and vectorial targeting of neurotrophins in neuroendocrine and epithelial cells. J. Biol. Chem. 271 (1996) 25430-25437
45. Hibbert A.P., Morris S.J., Seidah N.G., and Murphy R.A. Neurotrophin-4, alone or heterodimerized with brain-derived neurotrophic factor, is sorted to the constitutive secretory pathway. J. Biol. Chem. 278 (2003) 48129-48136
46. Itami C., Kimura F., Kohno T., Matsuoka M., Ichikawa M., Tsumoto T., and Nakamura S. Brain-derived neurotrophic factor-dependent unmasking of "silent" synapses in the developing mouse barrel cortex. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 13069-13074
47. 2+-dependent exocytosis: implications of kinetic diversity for secretory function. Trends Neurosci. 22 (1999) 88-93
48. Khatib A.M., Siegfried G., Chretien M., Metrakos P., and Seidah N.G. Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy. Am. J. Pathol. 160 (2002) 1921-1935
49. Khazipov R., and Luhmann H.J. Early patterns of electrical activity in the developing cerebral cortex of humans and rodents. Trends Neurosci. 29 (2006) 414-418
50. Kohara K., Kitamura A., Morishima M., and Tsumoto T. Activity-dependent transfer of brain-derived neurotrophic factor to postsynaptic neurons. Science 291 (2001) 2419-2423
51. Kohara K., Yasuda H., Huang Y., Adachi N., Sohya K., and Tsumoto T. A local reduction in cortical GABAergic synapses after a loss of endogenous brain-derived neurotrophic factor, as revealed by single-cell gene knock-out method. J. Neurosci. 27 (2007) 7234-7244
52. Kojima M., Takei N., Numakawa T., Ishikawa Y., Suzuki S., Matsumoto T., Katoh-Semba R., Nawa H., and Hatanaka H. Biological characterization and optical imaging of brain-derived neurotrophic factor-green fluorescent protein suggest an activity-dependent local release of brain-derived neurotrophic factor in neurites of cultured hippocampal neurons. J. Neurosci. Res. 64 (2001) 1-10
53. Kolarow R., Brigadski T., and Lessmann V. Postsynaptic secretion of BDNF and NT-3 from hippocampal neurons depends on calcium calmodulin kinase II signaling and proceeds via delayed fusion pore opening. J. Neurosci. 27 (2007) 10350-10364
54. Korte M., Griesbeck O., Gravel C., Carroll P., Staiger V., Thoenen H., and Bonhoeffer T. Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice. Proc Natl Acad Sci USA 93 (1996) 12547-12552
55. Kuczewski N., Porcher C., Ferrand N., Fiorentino H., Pellegrino C., Kolarow R., Lessmann V., Medina I., and Gaiarsa J.L. Backpropagating action potentials trigger dendritic release of BDNF during spontaneous network activity. J. Neurosci. 28 (2008) 7013-7023
56. Kuczewski N., Langlois A., Fiorentino H., Bonnet S., Marissal T., Diabira D., Ferrand N., Porcher C., and Gaiarsa J.L. Spontaneous glutamatergic activity induces a BDNF-dependent potentiation of GABAergic synapses in the newborn rat hippocampus. J. Physiol. 586 (2008) 5119-5128
57. Lang S.B., Stein V., Bonhoeffer T., and Lohmann C. Endogenous brain-derived neurotrophic factor triggers fast calcium transients at synapses in developing dendrites. J. Neurosci. 27 (2007) 1097-1105
58. Lee R., Kermani P., Teng K.K., and Hempstead B.L. Regulation of cell survival by secreted proneurotrophins. Science 294 (2001) 1945-1948
59. Leng G., and Ludwig M. Neurotransmitters and peptides: whispered secrets and public announcements. J. Physiol. 586 (2008) 5625-5632
60. Lessmann V., Gottmann K., and Malcangio M. Neurotrophin secretion: current facts and future prospects. Prog. Neurobiol. 69 (2003) 341-374
61. Lewin G.R., and Barde Y.A. Physiology of the neurotrophins. Annu. Rev. Neurosci. 19 (1996) 289-317
62. Lim K.C., Tyler C.M., Lim S.T., Giuliano R., and Federoff H.J. Proteolytic processing of proNGF is necessary for mature NGF regulated secretion from neurons. Biochem. Biophys. Res. Commun. 361 (2007) 599-604
63. Lochner J.E., Honigman L.S., Grant W.F., Gessford S.K., Hansen A.B., Silverman M.A., and Scalettar B.A. Activity-dependent release of tissue plasminogen activator from the dendritic spines of hippocampal neurons revealed by live-cell imaging. J. Neurobiol. 66 (2006) 564-577
64. Loh Y.P. Peptide precursor processing enzymes within secretory vesicles. Ann. N.Y. Acad. Sci. 493 (1987) 292-307
65. Lou H., Kim S.K., Zaitsev E., Snell C.R., Lu B., and Loh Y.P. Sorting and activity-dependent secretion of BDNF require interaction of a specific motif with the sorting receptor carboxypeptidase e. Neuron 45 (2005) 245-255
66. Lu Y., Christian K., and Lu B. BDNF: a key regulator for protein synthesis-dependent LTP and long-term memory?. Neurobiol. Learn. Mem. 89 (2008) 312-323
67. Ma G.Q., Wang B., Wang H.B., Wang Q., and Bao L. Short elements with charged amino acids form clusters to sort protachykinin into large dense-core vesicles. Traffic (2008)
68. Magby J.P., Bi C., Chen Z.Y., Lee F.S., and Plummer M.R. Single-cell characterization of retrograde signaling by brain-derived neurotrophic factor. J. Neurosci. 26 (2006) 13531-13536
69. Matsumoto T., Rauskolb S., Polack M., Klose J., Kolbeck R., Korte M., and Barde Y.A. Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF. Nat. Neurosci. 11 (2008) 131-133
70. Merighi A. Costorage and coexistence of neuropeptides in the mammalian CNS. Prog. Neurobiol. 66 (2002) 161-190
71. Minichiello L., Korte M., Wolfer D., Kuhn R., Unsicker K., Cestari V., Rossi-Arnaud C., Lipp H.P., Bonhoeffer T., and Klein R. Essential role for TrkB receptors in hippocampus-mediated learning. Neuron 24 (1999) 401-414
72. Mohajerani M.H., Sivakumaran S., Zacchi P., Aguilera P., and Cherubini E. Correlated network activity enhances synaptic efficacy via BDNF and the ERK pathway at immature CA3 CA1 connections in the hippocampus. Proc. Natl. Acad. Sci. U.S.A. 104 (2007) 13176-13181
73. Mowla S.J., Farhadi H.F., Pareek S., Atwal J.K., Morris S.J., Seidah N.G., and Murphy R.A. Biosynthesis and post-translational processing of the precursor to brain-derived neurotrophic factor. J. Biol. Chem. 276 (2001) 12660-12666
74. Mulcahy L.R., and Nillni E.A. Discovery of new peptides from old prohormones: insights for energy balance and beyond. Front. Biosci. 12 (2007) 3545-3553
75. Nakajima T., Sato M., Akaza N., and Umezawa Y. Cell-based fluorescent indicator to visualize brain-derived neurotrophic factor secreted from living neurons. ACS Chem. Biol. 3 (2008) 352-358
76. Nomoto H., Takaiwa M., Mouri A., and Furukawa S. Pro-region of neurotrophins determines the processing efficiency. Biochem. Biophys. Res. Commun. 356 (2007) 919-924
77. Nykjaer A., Lee R., Teng K.K., Jansen P., Madsen P., Nielsen M.S., Jacobsen C., Kliemannel M., Schwarz E., Willnow T.E., Hempstead B.L., and Petersen C.M. Sortilin is essential for proNGF-induced neuronal cell death. Nature 427 (2004) 843-848
78. Pang P.T., Teng H.K., Zaitsev E., Woo N.T., Sakata K., Zhen S., Teng K.K., Yung W.H., Hempstead B.L., and Lu B. Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity. Science 306 (2004) 487-491
79. Park J.J., Cawley N.X., and Loh Y.P. A bi-directional carboxypeptidase E-driven transport mechanism controls BDNF vesicle homeostasis in hippocampal neurons. Mol. Cell Neurosci. 39 (2008) 63-73
80. Patterson S.L., Pittenger C., Morozov A., Martin K.C., Scanlin H., Drake C., and Kandel E.R. Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase. Neuron 32 (2001) 123-140
81. Peng S., Wuu J., Mufson E.J., and Fahnestock M. Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease. J. Neurochem. 93 (2005) 1412-1421
82. Perrais D., Kleppe I.C., Taraska J.W., and Almers W. Recapture after exocytosis causes differential retention of protein in granules of bovine chromaffin cells. J. Physiol. 560 (2004) 413-428
83. Roebroek A.J., Creemers J.W., Ayoubi T.A., and Van d V. Furin-mediated proprotein processing activity: involvement of negatively charged amino acid residues in the substrate binding region. Biochimie 76 (1994) 210-216
84. Rosch H., Schweigreiter R., Bonhoeffer T., Barde Y.A., and Korte M. The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 7362-7367
85. Sadakata T., Mizoguchi A., Sato Y., Katoh-Semba R., Fukuda M., Mikoshiba K., and Furuichi T. The secretory granule-associated protein CAPS2 regulates neurotrophin release and cell survival. J. Neurosci. 24 (2004) 43-52
86. Salio C., Averill S., Priestley J.V., and Merighi A. Costorage of BDNF and neuropeptides within individual dense-core vesicles in central and peripheral neurons. Dev. Neurobiol. 67 (2007) 326-338
87. Santi S., Cappello S., Riccio M., Bergami M., Aicardi G., Schenk U., Matteoli M., and Canossa M. Hippocampal neurons recycle BDNF for activity-dependent secretion and LTP maintenance. EMBO J. 25 (2006) 4372-4380
88. Seidah N.G., Mowla S.J., Hamelin J., Mamarbachi A.M., Benjannet S., Toure B.B., Basak A., Munzer J.S., Marcinkiewicz J., Zhong M., Barale J.C., Lazure C., Murphy R.A., Chretien M., and Marcinkiewicz M. Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 1321-1326
89. Shakiryanova D., Tully A., Hewes R.S., Deitcher D.L., and Levitan E.S. Activity-dependent liberation of synaptic neuropeptide vesicles. Nat. Neurosci. 8 (2005) 173-178
90. Shakiryanova D., Tully A., and Levitan E.S. Activity-dependent synaptic capture of transiting peptidergic vesicles. Nat. Neurosci. 9 (2006) 896-900
91. Silverman M.A., Johnson S., Gurkins D., Farmer M., Lochner J.E., Rosa P., and Scalettar B.A. Mechanisms of transport and exocytosis of dense-core granules containing tissue plasminogen activator in developing hippocampal neurons. J. Neurosci. 25 (2005) 3095-3106
92. Smith M.A., Zhang L.X., Lyons W.E., and Mamounas L.A. Anterograde transport of endogenous brain-derived neurotrophic factor in hippocampal mossy fibers. Neuroreport 8 (1997) 1829-1834
93. Swanwick C.C., Harrison M.B., and Kapur J. Synaptic and extrasynaptic localization of brain-derived neurotrophic factor and the tyrosine kinase B receptor in cultured hippocampal neurons. J. Comp. Neurol. 478 (2004) 405-417
94. Tanaka J., Horiike Y., Matsuzaki M., Miyazaki T., Ellis-Davies G.C., and Kasai H. Protein synthesis and neurotrophin-dependent structural plasticity of single dendritic spines. Science 319 (2008) 1683-1687
95. Taraska J.W., Perrais D., Ohara-Imaizumi M., Nagamatsu S., and Almers W. Secretory granules are recaptured largely intact after stimulated exocytosis in cultured endocrine cells. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 2070-2075
96. Teng H.K., Teng K.K., Lee R., Wright S., Tevar S., Almeida R.D., Kermani P., Torkin R., Chen Z.Y., Lee F.S., Kraemer R.T., Nykjaer A., and Hempstead B.L. ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin. J. Neurosci. 25 (2005) 5455-5463
97. Thomas G. Furin at the cutting edge: From protein traffic to embryogenesis and disease. Nat. Rev. Mol. Cell Biol. 3 (2002) 753-766
98. Tongiorgi E., Righi M., and Cattaneo A. Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons. J. Neurosci. 17 (1997) 9492-9505
99. Tongiorgi E. Activity-dependent expression of brain-derived neurotrophic factor in dendrites: facts and open questions. Neurosci. Res. 61 (2008) 335-346
100. Tse F.W., and Tse A. Stimulation of Ca(2+)-independent exocytosis in rat pituitary gonadotrophs by G-protein. J. Physiol. 526 Pt. 1 (2000) 99-108
101. van Vliet C., Thomas E.C., Merino-Trigo A., Teasdale R.D., and Gleeson P.A. Intracellular sorting and transport of proteins. Prog. Biophys. Mol. Biol. 83 (2003) 1-45
102. Vardjan N., Stenovec M., Jorgacevski J., Kreft M., and Zorec R. Subnanometer fusion pores in spontaneous exocytosis of peptidergic vesicles. J. Neurosci. 27 (2007) 4737-4746
103. von Bartheld C.S., Wang X., and Butowt R. Anterograde axonal transport, transcytosis, and recycling of neurotrophic factors: the concept of trophic currencies in neural networks. Mol. Neurobiol. 24 (2001) 1-28
104. von Bartheld C.S. Axonal transport and neuronal transcytosis of trophic factors, tracers, and pathogens. J. Neurobiol. 58 (2004) 295-314
105. Walz C., Jungling K., Lessmann V., and Gottmann K. Presynaptic plasticity in an immature neocortical network requires NMDA receptor activation and BDNF release. J. Neurophysiol. 96 (2006) 3512-3516
106. Whim M.D., and Moss G.W. A novel technique that measures peptide secretion on a millisecond timescale reveals rapid changes in release. Neuron 30 (2001) 37-50
107. Woo N.H., Teng H.K., Siao C.J., Chiaruttini C., Pang P.T., Milner T.A., Hempstead B.L., and Lu B. Activation of p75NTR by proBDNF facilitates hippocampal long-term depression. Nat. Neurosci. 8 (2005) 1069-1077
108. Wu Y.J., Kruttgen A., Moller J.C., Shine D., Chan J.R., Shooter E.M., and Cosgaya J.M. Nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 are sorted to dense-core vesicles and released via the regulated pathway in primary rat cortical neurons. J. Neurosci. Res. 75 (2004) 825-834
109. Xia X., Lessmann V., and Martin T.F. Imaging of evoked dense-core-vesicle exocytosis in hippocampal neurons reveals long latencies and kiss-and-run fusion events. J. Cell Sci. 122 (2009) 75-82
110. Yan Q., Rosenfeld R.D., Matheson C.R., Hawkins N., Lopez O.T., Bennett L., and Welcher A.A. Expression of brain-derived neurotrophic factor protein in the adult rat central nervous system. Neuroscience 78 (1997) 431-448
111. Yang J., Siao C.J., Nagappan G., Marinic T., Jing D., McGrath K., Chen Z.Y., Mark W., Tessarollo L., Lee F.S., Lu B., and Hempstead B.L. Neuronal release of proBDNF. Nat. Neurosci. 12 (2009) 113-115
112. Yoshii A., and Constantine-Paton M. BDNF induces transport of PSD-95 to dendrites through PI3K-AKT signaling after NMDA receptor activation. Nat. Neurosci. 10 (2007) 702-711
113. Zakharenko S.S., Patterson S.L., Dragatsis I., Zeitlin S.O., Siegelbaum S.A., Kandel E.R., and Morozov A. Presynaptic BDNF required for a presynaptic but not postsynaptic component of LTP at hippocampal CA1-CA3 synapses. Neuron 39 (2003) 975-990
114. Zhou K.M., Dong Y.M., Ge Q., Zhu D., Zhou W., Lin X.G., Liang T., Wu Z.X., and Xu T. PKA activation bypasses the requirement for UNC-31 in the docking of dense core vesicles from C. elegans neurons. Neuron 56 (2007) 657-669
115. Zhou X.F., Song X.Y., Zhong J.H., Barati S., Zhou F.H., and Johnson S.M. Distribution and localization of pro-brain-derived neurotrophic factor-like immunoreactivity in the peripheral and central nervous system of the adult rat. J. Neurochem. 91 (2004) 704-715