Control of mitochondrial morphology by a human mitofusin

Journal of Cell Science

Volumn 114, Issue 5, 2001, Pages 867-874

  Santel, Ansgar ^a   Fuller, Margaret T ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dynamin related protein; Fzo; GTPase; Human; Mitochondrial fusion; Mitofusin

Indexed keywords

CELL PROTEIN; DYNAMIN; GUANOSINE TRIPHOSPHATASE; HYBRID PROTEIN; INSECT PROTEIN; MEMBRANE PROTEIN; MITOFUSIN DERIVATIVE; MUTANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL FUSION; CELL ORGANELLE; CONTROLLED STUDY; DROSOPHILA; ENZYME ACTIVITY; GENETIC ANALYSIS; GENETIC CODE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDROPHOBICITY; MAMMAL CELL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MORPHOGENESIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN TARGETING; REGULATORY MECHANISM; SEQUENCE HOMOLOGY; YEAST;

ANIMALS; CELL LINE; FLUORESCENT ANTIBODY TECHNIQUE; GTP PHOSPHOHYDROLASES; HUMANS; MITOCHONDRIA; RECEPTORS, CXCR4;

ALLIUM CEPA; ANIMALIA; INSECTA; MAMMALIA;

EID: 0035057837     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Altschul, S. F., Gish, W., Miller, W., Myers, E. W. and Lipman, D. J. (1990). Basic local alignment search tool. J. Mol. Biol. 215, 403-410.
2. Arbustini, E., Diegoli, M., Fasani, R., Grasso, M., Morbini, P., Banchieri, N., Bellini, O., Dal Bello, B., Pilotto, A., Magrini, G. et al. (1998). Mitochondrial DNA mutations and mitochondrial abnormalities in dilated cardiomyopathy. Am. J. Pathol 153, 1501-1510.
3. Bakeeva, L. E., Chentsov, Y. S. and Skulachev, V. P. (1981). Ontogenesis of mitochondrial reticulum in rat diaphraam muscle. Eur. J. Cell Biol. 25, 175-181.
4. Bleazard, W., McCaffery, J. M., King, E. J., Bale, S., Mozdy, A., Tieu, Q., Nunnari, J. and Shaw, J. M. (1999). The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast. Nat. Cell Biol. 1, 298-304.
5. Bourne, H. R., Sanders, D. A. and McCormick, F. (1991). The GTPase superfamily: conserved structure and molecular mechanism. Nature 349, 117-127.
6. Hales, K. G. and Fuller, M. T. (1997). Developmentally regulated mitochondrial fusion mediated by a conserved, novel, predicted GTPase. Cell 90, 121-129.
7. Hermann, G. J. and Shaw, J. M. (1998). Mitochondrial dynamics in yeast. Annu. Rev. Cell Dev. Biol. 14, 265-303.
8. Hermann, G. J., Thatcher, J. W., Mills, J. P., Hales, K. G., Fuller, M. T., Nunnari, J. and Shaw, J. M. (1998). Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p. J. Cell. Biol. 143, 359-373.
9. Inagaki, T., Kobayashi, S., Ozeki, N., Suzuki, M., Fukuzawa, Y., Shimizu, K. and Kato, K. (1992). Ultrastructural identification of light microscopic giant mitochondria in alcoholic liver disease. Hepatology 15, 46-53.
10. Kirkwood, S. P., Munn, E. A. and Brooks, G. A. (1986). Mitochondrial reticulum in limb skeletal muscle. Am. J. Physiol. 251, C395-402.
11. Knabe, W. and Kuhn, H. J. (1996). Morphogenesis of megamitochondria in the retinal cone inner segments of Tupaia belangen (Scandentia). Cell Tissue Res. 285, 1-9.
12. Labrousse, A. M., Zappaterra, M. D., Rube, D. A. and van der Bliek, A. M. (1999). C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane. Mol Cell 4, 815-826.
13. Larsson, N. G., Wang, J., Wilhelmsson, H., Oldfors, A., Rustin, P., Lewandoski, M., Barsh, G. S. and Clayton, D. A. (1998). Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. Nat. Genet. 18, 231-236.
14. Lupas, A., Van Dyke, M. and Stock, J. (1991). Predicting coiled coils from protein sequences. Science 252, 1162-1164.
15. Nagase, T., Seki, N., Ishikawa, K., Ohira, M., Kawarabayasi, Y., Ohara, O., Tanaka, A., Kotani, H., Miyajima, N. and Nomura, N. (1996). Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. DNA Res. 3, 321-9, 341-54.
16. Nakai, K. and Horton, P. (1999). PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization. Trends Biochem. Sci. 24, 34-36.
17. Nemoto, Y. and De Camilli, P. (1999). Recruitment of an alternatively spliced form of synaptojanin 2 to mitochondria by the interaction with the PDZ domain of a mitochondrial outer membrane protein. EMBO J. 18, 2991-3006.
18. Nunnari, J., Marshall, W. F., Straight, A., Murray, A., Sedat, J. W. and Walter, P. (1997). Mitochondrial transmission during mating in Saccharomyces cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mitochondrial DNA. Mol. Biol. Cell 8, 1233-1242.
19. Olson, G. E. and Winfrey, V. P. (1992). Structural organization of surface domains of sperm mitochondria. Mol. Reprod. Dev. 33, 89-98.