Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

Journal of Biological Chemistry

Volumn 278, Issue 10, 2003, Pages 7743-7746

  Olichon, Aurélien ^a   Baricault, Laurent ^a   Gas, Nicole ^a   Guillou, Emmanuelle ^a   Valette, Annie ^a   Belenguer, Pascale ^a   Lenaers, Guy ^a  

^a Institut d'Exploration Fonctionnelle des Génomes   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; PATHOLOGY; PHYSIOLOGY; RNA;

MEMBRANE STRUCTURE;

CELL MEMBRANES;

CASPASE; CYTOCHROME C; GUANOSINE TRIPHOSPHATASE; MITOCHONDRIAL PROTEIN; PROTEIN BCL 2; PROTEIN OPA1; RNA; UNCLASSIFIED DRUG; OPA1 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; GENE OVEREXPRESSION; HELA CELL; HEREDITARY OPTIC ATROPHY; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MEMBRANE STRUCTURE; MITOCHONDRIAL MEMBRANE; NERVE DEGENERATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RETINA GANGLION CELL; CELL CULTURE; ELECTRON MICROSCOPY; ENZYMOLOGY; GENETICS; INTRACELLULAR MEMBRANE; METABOLISM; MITOCHONDRION; PHYSIOLOGY; ULTRASTRUCTURE;

APOPTOSIS; CYTOCHROME C GROUP; GTP PHOSPHOHYDROLASES; HUMANS; INTRACELLULAR MEMBRANES; MICROSCOPY, ELECTRON; MITOCHONDRIA; TUMOR CELLS, CULTURED;

EID: 0037424239     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C200677200     Document Type: Article

References (27)

1. Olichon, A., Emorine, L. J., Descoins, E., Pelloquin, L., Brichese, L., Gas, N., Guillou, E., Delettre, C., Valette, A., Hamel, C. P., Ducommun, B., Lenaers, G., and Belenguer, P. (2002) FEBS Lett. 523, 171-176
2. Alexander, C., Votruba, M., Pesch, U. E., Thiselton, D. L., Mayer, S., Moore, A., Rodriguez, M., Kellner, U., Leo-Kottler, B., Auburger, G., Bhattacharya, S. S., and Wissinger, B. (2000) Nat. Genet. 26, 211-215
3. Delettre, C., Lenaers, G., Griffoin, J. M., Gigarel, N., Lorenzo, C., Belenguer, P., Pelloquin, L., Grosgeorge, J, Turc-Carel, C., Perret, E., Astarie-Dequeker, C., Lasquellec, L., Arnaud, B., Ducommun, B., Kaplan, J., and Hamel, C. P. (2000) Nat. Genet. 26, 207-210
4. Thiselton, D. L., Alexander, C., Taanman, J. W., Brooks, S., Rosenberg, T., Eiberg, H., Andreasson, S., Van Regemorter, N., Munier, F. L., Moore, A. T., Bhattacharya, S. S., and Votruba, M. (2002) Invest. Ophthalmol. Vis. Sci. 43, 1715-1724
5. Kjer, P., Jensen, O. A., and Klinken, L. (1983) Acta Ophthalmol. (Copenh.) 61, 300-312
6. Danino, D., and Hinshaw, J. E. (2001) Curr. Opin. Cell Biol. 13, 454-460
7. van der Bliek, A. M. (1999) Trends Cell Biol. 9, 96-102
8. Bleazard, W., McCaffery, J. M., King, E. J., Bale, S., Mozdy, A., Tieu, Q., Nunnari, J., and Shaw, J. M. (1999) Nat. Cell Biol. 1, 298-304
9. Smirnova, E., Shurland, D. L., Ryazantsev, S. N., and van der Bliek, A. M. (1998) J. Cell Biol. 143, 351-358
10. Jones, B. A., and Fangman, W. L. (1992) Genes Dev. 6, 380-389
11. Pelloquin, L., Belenguer, P., Menon, Y., Gas, N., and Ducommun, B. (1999) J. Cell Sci. 112, 4151-4161
12. Shepard, K. A., and Yaffe, M. P. (1999) J. Cell Biol. 144, 711-720
13. Wong, E. D., Wagner, J. A., Gorsich, S. W., McCaffery, J. M., Shaw, J. M., and Nunnari, J. (2000) J. Cell Biol. 151, 341-352
14. Stowell, M. H., Marks, B., Wigge, P., and McMahon, H. T. (1999) Nat. Cell Biol. 1, 27-32
15. Sever, S., Damke, H., and Schmid, S. L. (2000) Traffic 1, 385-392
16. Mannella, C. A., Pfeiffer, D. R., Bradshaw, P. C., Moraru, I. I., Slepchenko, B., Loew, L. M., Hsieh, C. E., Buttle, K., and Marko, M. (2001) Dig. Liver Dis. 33, 795-802
17. Bernardi, P., and Azzone, G. F. (1981) J. Biol. Chem. 256, 7187-7192
18. Scorrano, L., Ashiya, M., Buttle, K., Weiler, S., Oakes, S. A., Mannella, C. A., and Korsmeyer, S. J. (2002) Dev. Cell 2, 55-67
19. Lafon, C., Mathieu, C., Guerrin, M., Pierre, O., Vidal, S., and Valette, A. (1996) Cell Growth Differ. 7, 1095-1104
20. Elbashir, S. M., Harborth, J., Weber, K., and Tuschl, T. (2002) Methods 26, 199-213
21. Delettre, C., Griffoin, J. M., Kaplan, J., Dollfus, H., Lorenz, B., Faivre, L., Lenaers, G., Belenguer, P., and Hamel, C. P. (2001) Hum. Genet. 109, 584-591
22. Castedo, M., Ferri, K., Roumier, T., Metivier, D., Zamzami, N., and Kroemer, G. (2002) J. Immunol. Methods 265, 39-47
23. Legros, F., Lombes, A., Frachon, P., and Rojo, M. (2002) Mol. Biol. Cell 13, 4343-4354
24. Desagher, S., and Martinou, J. C. (2000) Trends Cell Biol. 10, 369-377
25. Sallmann, F. R., Bourassa, S., Saint-Cyr, J., and Poirier, G. G. (1997) Biochem. Cell Biol. 75, 451-456
26. Frank, S., Gaume, B., Bergmann-Leitner, E. S., Leitner, W. W., Robert, E. G., Catez, F., Smith, C. L., and Youle, R. J. (2001) Dev. Cell 1, 515-525
27. Farkas, R. H., and Grosskreutz, C. L. (2002) Ophthalmol. Clin. North Am. 15, 61-68