메뉴 건너뛰기




Volumn 10, Issue 11, 2007, Pages 1449-1457

Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury

Author keywords

[No Author keywords available]

Indexed keywords

NEUROTROPIN; RECEPTOR PROTEIN; SORTILIN; UNCLASSIFIED DRUG;

EID: 35548930820     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn2000     Document Type: Article
Times cited : (246)

References (50)
  • 1
    • 0037762690 scopus 로고    scopus 로고
    • Neurotrophins and their receptors: A convergence point for many signaling pathways
    • Chao, M.V. Neurotrophins and their receptors: a convergence point for many signaling pathways. Nat. Rev. Neurosci. 4, 299-309 (2003).
    • (2003) Nat. Rev. Neurosci , vol.4 , pp. 299-309
    • Chao, M.V.1
  • 3
    • 0033358870 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor influences NT-3 responsiveness of sympathetic neurons in vivo
    • Brennan, C., Rivas-Plata, K. & Landis, S.C. The p75 neurotrophin receptor influences NT-3 responsiveness of sympathetic neurons in vivo. Nat. Neurosci. 2, 699-705 (1999).
    • (1999) Nat. Neurosci , vol.2 , pp. 699-705
    • Brennan, C.1    Rivas-Plata, K.2    Landis, S.C.3
  • 4
    • 0032559622 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death
    • Bamji, S.X. et al. The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death. J. Cell Biol. 140, 911-923 (1998).
    • (1998) J. Cell Biol , vol.140 , pp. 911-923
    • Bamji, S.X.1
  • 5
    • 0032968762 scopus 로고    scopus 로고
    • Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord
    • Frade, J.M. & Barde, Y.A. Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord. Development 126, 683-690 (1999).
    • (1999) Development , vol.126 , pp. 683-690
    • Frade, J.M.1    Barde, Y.A.2
  • 6
    • 0037168106 scopus 로고    scopus 로고
    • ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury
    • Beattie, M.S. et al. ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury. Neuron 36, 375-386 (2002).
    • (2002) Neuron , vol.36 , pp. 375-386
    • Beattie, M.S.1
  • 7
    • 11144355567 scopus 로고    scopus 로고
    • Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury
    • Harrington, A.W. et al. Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury. Proc. Natl. Acad. Sci. USA 101, 6226-6230 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 6226-6230
    • Harrington, A.W.1
  • 8
    • 0029805770 scopus 로고    scopus 로고
    • Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75
    • Casaccia-Bonnefil, P., Carter, B.D., Dobrowsky, R.T. & Chao, M.V. Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75. Nature 383, 716-719 (1996).
    • (1996) Nature , vol.383 , pp. 716-719
    • Casaccia-Bonnefil, P.1    Carter, B.D.2    Dobrowsky, R.T.3    Chao, M.V.4
  • 9
    • 33646052860 scopus 로고    scopus 로고
    • Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons
    • Kenchappa, R.S. et al. Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons. Neuron 50, 219-232 (2006).
    • (2006) Neuron , vol.50 , pp. 219-232
    • Kenchappa, R.S.1
  • 10
    • 0000326996 scopus 로고    scopus 로고
    • Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival
    • Yoon, S.O., Casaccia-Bonnefil, P., Carter, B. & Chao, M.V. Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival. J. Neurosci. 18, 3273-3281 (1998).
    • (1998) J. Neurosci , vol.18 , pp. 3273-3281
    • Yoon, S.O.1    Casaccia-Bonnefil, P.2    Carter, B.3    Chao, M.V.4
  • 11
    • 0035976524 scopus 로고    scopus 로고
    • Regulation of cell survival by secreted pro-neurotrophins
    • Lee, R., Kermani, P., Teng, K.K. & Hempstead, B.L. Regulation of cell survival by secreted pro-neurotrophins. Science 294, 1945-1948 (2001).
    • (2001) Science , vol.294 , pp. 1945-1948
    • Lee, R.1    Kermani, P.2    Teng, K.K.3    Hempstead, B.L.4
  • 12
    • 10744219632 scopus 로고    scopus 로고
    • Sortilin is essential for proNGF-induced neuronal cell death
    • Nykjaer, A. et al. Sortilin is essential for proNGF-induced neuronal cell death. Nature 427, 843-848 (2004).
    • (2004) Nature , vol.427 , pp. 843-848
    • Nykjaer, A.1
  • 13
    • 20044370999 scopus 로고    scopus 로고
    • NTR and sortilin
    • NTR and sortilin. J. Neurosci. 25, 5455-5463 (2005).
    • (2005) J. Neurosci , vol.25 , pp. 5455-5463
    • Teng, H.K.1
  • 14
    • 33747051514 scopus 로고    scopus 로고
    • Interaction of survival and death signaling in basal forebrain neurons: Roles of neurotrophins and pro-neurotrophins
    • Volosin, M. et al. Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and pro-neurotrophins. J. Neurosci. 26, 7756-7766 (2006).
    • (2006) J. Neurosci , vol.26 , pp. 7756-7766
    • Volosin, M.1
  • 15
    • 33646241085 scopus 로고    scopus 로고
    • Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor and its degradation by a protease cascade
    • Bruno, M.A. & Cuello, A.C. Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor and its degradation by a protease cascade. Proc. Natl. Acad. Sci. USA 103, 6735-6740 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 6735-6740
    • Bruno, M.A.1    Cuello, A.C.2
  • 16
    • 2342550552 scopus 로고    scopus 로고
    • Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons
    • Chen, Z.Y. et al. Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons. J. Neurosci. 24, 4401-4411 (2004).
    • (2004) J. Neurosci , vol.24 , pp. 4401-4411
    • Chen, Z.Y.1
  • 17
    • 33846389267 scopus 로고    scopus 로고
    • Pro-NGF secreted by astrocytes promotes motor neuron cell death
    • Domeniconi, M., Hempstead, B.L. & Chao, M.V. Pro-NGF secreted by astrocytes promotes motor neuron cell death. Mol. Cell. Neurosci. 34, 271-279 (2007).
    • (2007) Mol. Cell. Neurosci , vol.34 , pp. 271-279
    • Domeniconi, M.1    Hempstead, B.L.2    Chao, M.V.3
  • 18
    • 0033231183 scopus 로고    scopus 로고
    • The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death
    • Casademunt, E. et al. The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death. EMBO J. 18, 6050-6061 (1999).
    • (1999) EMBO J , vol.18 , pp. 6050-6061
    • Casademunt, E.1
  • 19
    • 17144418443 scopus 로고    scopus 로고
    • Neurotrophin receptor interacting factor (NRIF) is an essential mediator of apoptotic signaling by the p75 neurotrophin receptor
    • Linggi, M.S. et al. Neurotrophin receptor interacting factor (NRIF) is an essential mediator of apoptotic signaling by the p75 neurotrophin receptor. J. Biol. Chem. 280, 13801-13808 (2005).
    • (2005) J. Biol. Chem , vol.280 , pp. 13801-13808
    • Linggi, M.S.1
  • 20
    • 16944367478 scopus 로고    scopus 로고
    • Transgenic mice expressing the intracellular domain of the p75 neurotrophin receptor undergo neuronal apoptosis
    • Majdan, M. et al. Transgenic mice expressing the intracellular domain of the p75 neurotrophin receptor undergo neuronal apoptosis. J. Neurosci. 17, 6988-6998 (1997).
    • (1997) J. Neurosci , vol.17 , pp. 6988-6998
    • Majdan, M.1
  • 21
    • 2942536284 scopus 로고    scopus 로고
    • Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease
    • Peng, S., Wuu, J., Mufson, E.J. & Fahnestock, M. Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease. J. Neuropathol. Exp. Neurol. 63, 641-649 (2004).
    • (2004) J. Neuropathol. Exp. Neurol , vol.63 , pp. 641-649
    • Peng, S.1    Wuu, J.2    Mufson, E.J.3    Fahnestock, M.4
  • 22
    • 0034848604 scopus 로고    scopus 로고
    • The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease
    • Fahnestock, M., Michalski, B., Xu, B. & Coughlin, M.D. The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease. Mol. Cell. Neurosci. 18, 210-220 (2001).
    • (2001) Mol. Cell. Neurosci , vol.18 , pp. 210-220
    • Fahnestock, M.1    Michalski, B.2    Xu, B.3    Coughlin, M.D.4
  • 23
    • 33748745125 scopus 로고    scopus 로고
    • Increased pro-nerve growth factor and p75 neurotrophin receptor levels in developing hypothyroid rat cerebral cortex are associated with enhanced apoptosis
    • Kumar, A. et al. Increased pro-nerve growth factor and p75 neurotrophin receptor levels in developing hypothyroid rat cerebral cortex are associated with enhanced apoptosis. Endocrinology 147, 4893-4903 (2006).
    • (2006) Endocrinology , vol.147 , pp. 4893-4903
    • Kumar, A.1
  • 24
    • 14444281750 scopus 로고    scopus 로고
    • Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography
    • Petersen, C.M. et al. Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography. J. Biol. Chem. 272, 3599-3605 (1997).
    • (1997) J. Biol. Chem , vol.272 , pp. 3599-3605
    • Petersen, C.M.1
  • 25
    • 0027324122 scopus 로고
    • Induction of apoptosis by the low-affinity NGF receptor
    • Rabizadeh, S. et al. Induction of apoptosis by the low-affinity NGF receptor. Science 261, 345-348 (1993).
    • (1993) Science , vol.261 , pp. 345-348
    • Rabizadeh, S.1
  • 26
    • 0035945344 scopus 로고    scopus 로고
    • TrkA mediates developmental sympathetic neuron survival in vivo by silencing an ongoing p75NTR-mediated death signal
    • Majdan, M., Walsh, G.S., Aloyz, R. & Miller, F.D. TrkA mediates developmental sympathetic neuron survival in vivo by silencing an ongoing p75NTR-mediated death signal. J. Cell Biol. 155, 1275-1285 (2001).
    • (2001) J. Cell Biol , vol.155 , pp. 1275-1285
    • Majdan, M.1    Walsh, G.S.2    Aloyz, R.3    Miller, F.D.4
  • 27
    • 0028265280 scopus 로고
    • Nerve growth factor enhances the dendritic arborization of sympathetic ganglion cells undergoing atrophy in aged rats
    • Andrews, T.J. & Cowen, T. Nerve growth factor enhances the dendritic arborization of sympathetic ganglion cells undergoing atrophy in aged rats. J. Neurocytol. 23, 234-241 (1994).
    • (1994) J. Neurocytol , vol.23 , pp. 234-241
    • Andrews, T.J.1    Cowen, T.2
  • 28
    • 10844242983 scopus 로고    scopus 로고
    • The role of NGF uptake in selective vulnerability to cell death in ageing sympathetic neurons
    • Gatzinsky, K.P., Thrasivoulou, C., Campioni-Noack, M., Underwood, C. & Cowen, T. The role of NGF uptake in selective vulnerability to cell death in ageing sympathetic neurons. Eur. J. Neurosci. 20, 2848-2856 (2004).
    • (2004) Eur. J. Neurosci , vol.20 , pp. 2848-2856
    • Gatzinsky, K.P.1    Thrasivoulou, C.2    Campioni-Noack, M.3    Underwood, C.4    Cowen, T.5
  • 29
    • 0028924510 scopus 로고
    • Pathologic alterations in pre- and postsynaptic elements in aged mouse sympathetic ganglia
    • Schmidt, R.E., Beaudet, L., Plurad, S.B., Snider, W.D. & Ruit, K.G. Pathologic alterations in pre- and postsynaptic elements in aged mouse sympathetic ganglia. J. Neurocytol. 24, 189-206 (1995).
    • (1995) J. Neurocytol , vol.24 , pp. 189-206
    • Schmidt, R.E.1    Beaudet, L.2    Plurad, S.B.3    Snider, W.D.4    Ruit, K.G.5
  • 30
    • 0842348861 scopus 로고    scopus 로고
    • Heterogeneous requirement of NGF for sympathetic target innervation in vivo
    • Glebova, N.O. & Ginty, D.D. Heterogeneous requirement of NGF for sympathetic target innervation in vivo. J. Neurosci. 24, 743-751 (2004).
    • (2004) J. Neurosci , vol.24 , pp. 743-751
    • Glebova, N.O.1    Ginty, D.D.2
  • 31
    • 0028294595 scopus 로고
    • Dependence on p75 for innervation of some sympathetic targets
    • Lee, K.F., Bachman, K., Landis, S. & Jaenisch, R. Dependence on p75 for innervation of some sympathetic targets. Science 263, 1447-1449 (1994).
    • (1994) Science , vol.263 , pp. 1447-1449
    • Lee, K.F.1    Bachman, K.2    Landis, S.3    Jaenisch, R.4
  • 32
    • 0033525377 scopus 로고    scopus 로고
    • Expression of the 100-kDa neurotensin receptor sortilin during mouse embryonal development
    • Hermans-Borgmeyer, I., Hermey, G., Nykjaer, A. & Schaller, C. Expression of the 100-kDa neurotensin receptor sortilin during mouse embryonal development. Brain Res. Mol. Brain Res. 65, 216-219 (1999).
    • (1999) Brain Res. Mol. Brain Res , vol.65 , pp. 216-219
    • Hermans-Borgmeyer, I.1    Hermey, G.2    Nykjaer, A.3    Schaller, C.4
  • 33
    • 30544439000 scopus 로고    scopus 로고
    • Effect of p75NTR on the regulation of naturally occurring cell death and retinal ganglion cell number in the mouse eye
    • Harada, C. et al. Effect of p75NTR on the regulation of naturally occurring cell death and retinal ganglion cell number in the mouse eye. Dev. Biol. 290, 57-65 (2006).
    • (2006) Dev. Biol , vol.290 , pp. 57-65
    • Harada, C.1
  • 34
    • 0031934936 scopus 로고    scopus 로고
    • Microglia-derived nerve growth factor causes cell death in the developing retina
    • Frade, J.M. & Barde, Y.A. Microglia-derived nerve growth factor causes cell death in the developing retina. Neuron 20, 35-41 (1998).
    • (1998) Neuron , vol.20 , pp. 35-41
    • Frade, J.M.1    Barde, Y.A.2
  • 35
    • 0035341211 scopus 로고    scopus 로고
    • The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein
    • Nielsen, M.S. et al. The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein. EMBO J. 20, 2180-2190 (2001).
    • (2001) EMBO J , vol.20 , pp. 2180-2190
    • Nielsen, M.S.1
  • 36
    • 0034927081 scopus 로고    scopus 로고
    • Neurotrophins: Roles in neuronal development and function
    • Huang, E.J. & Reichardt, L.F. Neurotrophins: roles in neuronal development and function. Annu. Rev. Neurosci. 24, 677-736 (2001).
    • (2001) Annu. Rev. Neurosci , vol.24 , pp. 677-736
    • Huang, E.J.1    Reichardt, L.F.2
  • 37
    • 23244441099 scopus 로고    scopus 로고
    • Growth and survival signals controlling sympathetic nervous system development
    • Glebova, N.O. & Ginty, D.D. Growth and survival signals controlling sympathetic nervous system development. Annu. Rev. Neurosci. 28, 191-222 (2005).
    • (2005) Annu. Rev. Neurosci , vol.28 , pp. 191-222
    • Glebova, N.O.1    Ginty, D.D.2
  • 38
    • 0028196552 scopus 로고
    • p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF
    • Lee, K.F., Davies, A.M. & Jaenisch, R. p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF. Development 120, 1027-1033 (1994).
    • (1994) Development , vol.120 , pp. 1027-1033
    • Lee, K.F.1    Davies, A.M.2    Jaenisch, R.3
  • 40
    • 0025310427 scopus 로고
    • Nerve growth factor (NGF), proNGF and NGF receptor-like immunoreactivity in BB rat retina
    • Chakrabarti, S., Sima, A.A., Lee, J., Brachet, P. & Dicou, E. Nerve growth factor (NGF), proNGF and NGF receptor-like immunoreactivity in BB rat retina. Brain Res. 523, 11-15 (1990).
    • (1990) Brain Res , vol.523 , pp. 11-15
    • Chakrabarti, S.1    Sima, A.A.2    Lee, J.3    Brachet, P.4    Dicou, E.5
  • 41
    • 33751208303 scopus 로고    scopus 로고
    • Increased NGF proforms in aged sympathetic neurons and their targets
    • Bierl, M.A. & Isaacson, L.G. Increased NGF proforms in aged sympathetic neurons and their targets. Neurobiol. Aging 28, 122-134 (2007).
    • (2007) Neurobiol. Aging , vol.28 , pp. 122-134
    • Bierl, M.A.1    Isaacson, L.G.2
  • 42
    • 0042886033 scopus 로고    scopus 로고
    • Sympathetic neurons synthesize and secrete pro-nerve growth factor protein
    • Hasan, W., Pedchenko, T., Krizsan-Agbas, D., Baum, L. & Smith, P.G. Sympathetic neurons synthesize and secrete pro-nerve growth factor protein. J. Neurobiol. 57, 38-53 (2003).
    • (2003) J. Neurobiol , vol.57 , pp. 38-53
    • Hasan, W.1    Pedchenko, T.2    Krizsan-Agbas, D.3    Baum, L.4    Smith, P.G.5
  • 43
    • 0021767870 scopus 로고
    • Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues
    • Heumann, R., Korsching, S., Scott, J. & Thoenen, H. Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues. EMBO J. 3, 3183-3189 (1984).
    • (1984) EMBO J , vol.3 , pp. 3183-3189
    • Heumann, R.1    Korsching, S.2    Scott, J.3    Thoenen, H.4
  • 44
    • 0026747063 scopus 로고
    • Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system
    • Lee, K.F. et al. Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell 69, 737-749 (1992).
    • (1992) Cell , vol.69 , pp. 737-749
    • Lee, K.F.1
  • 45
    • 0034738320 scopus 로고    scopus 로고
    • An axotomy model for the induction of death of rat and mouse corticospinal neurons in vivo
    • Bonatz, H., Rohrig, S., Mestres, P., Meyer, M. & Giehl, K.M. An axotomy model for the induction of death of rat and mouse corticospinal neurons in vivo. J. Neurosci. Methods 100, 105-115 (2000).
    • (2000) J. Neurosci. Methods , vol.100 , pp. 105-115
    • Bonatz, H.1    Rohrig, S.2    Mestres, P.3    Meyer, M.4    Giehl, K.M.5
  • 46
    • 0029989784 scopus 로고    scopus 로고
    • BDNF and NT-3, but not NGF, prevent axotomy-induced death of rat corticospinal neurons in vivo
    • Giehl, K.M. & Tetzlaff, W. BDNF and NT-3, but not NGF, prevent axotomy-induced death of rat corticospinal neurons in vivo. Eur. J. Neurosci. 8, 1167-1175 (1996).
    • (1996) Eur. J. Neurosci , vol.8 , pp. 1167-1175
    • Giehl, K.M.1    Tetzlaff, W.2
  • 47
    • 0035873457 scopus 로고    scopus 로고
    • Endogenous brain-derived neurotrophic factor and neurotrophin-3 antagonistically regulate survival of axotomized corticospinal neurons in vivo
    • Giehl, K.M. et al. Endogenous brain-derived neurotrophic factor and neurotrophin-3 antagonistically regulate survival of axotomized corticospinal neurons in vivo. J. Neurosci. 21, 3492-3502 (2001).
    • (2001) J. Neurosci , vol.21 , pp. 3492-3502
    • Giehl, K.M.1
  • 48
    • 0026530168 scopus 로고
    • The isector: A simple and direct method for generating isotropic, uniform random sections from small specimens
    • Nyengaard, J.R. & Gundersen, H.J.G. The isector: a simple and direct method for generating isotropic, uniform random sections from small specimens. J. Microsc. 165, 427-431 (1991).
    • (1991) J. Microsc , vol.165 , pp. 427-431
    • Nyengaard, J.R.1    Gundersen, H.J.G.2
  • 49
    • 0035693652 scopus 로고    scopus 로고
    • Tissue shrinkage and unbiased stereological estimation of particle number and size
    • Dorph-Petersen, K.A., Nyengaard, J.R. & Gundersen, H.J. Tissue shrinkage and unbiased stereological estimation of particle number and size. J. Microsc. 204, 232-246 (2001).
    • (2001) J. Microsc , vol.204 , pp. 232-246
    • Dorph-Petersen, K.A.1    Nyengaard, J.R.2    Gundersen, H.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.