Personalizing colon cancer therapeutics: Targeting old and new mechanisms of action

Pharmaceuticals

Volumn 6, Issue 8, 2013, Pages 988-1038

  Kline, Christina Leah B ^a   El Deiry, Wafik S ^a  

^a PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

Colorectal cancer; Genetic polymorphisms; Personalized medicine

Indexed keywords

AFLIBERCEPT; BEVACIZUMAB; CAPECITABINE; CETUXIMAB; CISPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; FIRTECAN; FLUOROURACIL; FOLINIC ACID; GEFITINIB; IRINOTECAN; METHYLENETETRAHYDROFOLIC ACID; OXALIPLATIN; PANITUMUMAB; PEMETREXED; RALTITREXED; REGORAFENIB; RG7 204; SORAFENIB; UNCLASSIFIED DRUG; VASCULOTROPIN INHIBITOR; VEMURAFENIB;

ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; BONE MARROW SUPPRESSION; CANCER CELL; CANCER CHEMOTHERAPY; CANCER PROGNOSIS; CANCER RESISTANCE; CANCER STAGING; CANCER STEM CELL; CANCER SURVIVAL; CIRCULATING TUMOR CELL; CLINICAL TRIAL (TOPIC); COLON CANCER; COLORECTAL CANCER; CONTINUOUS INFUSION; DIARRHEA; DNA DAMAGE; DRUG BLOOD LEVEL; DRUG CHOICE; DRUG DNA BINDING; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG FATALITY; DRUG METABOLISM; DRUG SAFETY; DRUG STRUCTURE; DRUG TARGETING; DRUG TREATMENT FAILURE; GASTROINTESTINAL TOXICITY; GENETIC ANALYSIS; HAND FOOT SYNDROME; HUMAN; MEDICAL DECISION MAKING; MELANOMA; MICROSATELLITE INSTABILITY; MULTIPLE CYCLE TREATMENT; NEUROTOXICITY; NONHUMAN; OVERALL SURVIVAL; PATIENT SELECTION; PERSONALIZED MEDICINE; PHARMACOGENETICS; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PROTEIN EXPRESSION; REVIEW; RISK BENEFIT ANALYSIS; SENSORY NEUROPATHY; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SURVIVAL TIME; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT;

EID: 84882764711     PISSN: None     EISSN: 14248247     Source Type: Journal    
DOI: 10.3390/ph6080988     Document Type: Review

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