-
1
-
-
0023902287
-
Familial deficiency of dihydropyrimidine dehydrogenase
-
Diasio, R. B., Beavers, T. L., and Carpenter, J. T. Familial deficiency of dihydropyrimidine dehydrogenase. J. Clin. Invest., 81 47-51, 1988.
-
(1988)
J. Clin. Invest.
, vol.81
, pp. 47-51
-
-
Diasio, R.B.1
Beavers, T.L.2
Carpenter, J.T.3
-
2
-
-
0025990479
-
Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency a potentially more common pharmacogenetic syndrome
-
Phila.
-
Harris, B. E., Carpenter, J. T., and Diasio, R. B. Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency a potentially more common pharmacogenetic syndrome. Cancer (Phila.), 68: 499-501, 1991.
-
(1991)
Cancer
, vol.68
, pp. 499-501
-
-
Harris, B.E.1
Carpenter, J.T.2
Diasio, R.B.3
-
3
-
-
0027426408
-
Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: Population characteristics, newly identified deficient patients and clinical implication in 5-fluorouracil chemotherapy
-
Lu, Z., Zhang, R., and Diasio, R. B. Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: population characteristics, newly identified deficient patients and clinical implication in 5-fluorouracil chemotherapy. Cancer Res., 53: 5433-5438, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 5433-5438
-
-
Lu, Z.1
Zhang, R.2
Diasio, R.B.3
-
4
-
-
9044219595
-
Genetic polymorphism of dihydropyrimidine dehydrogenase:Implications for 5-fluorouracil metabolism and toxicity
-
Diasio, R. B. Genetic polymorphism of dihydropyrimidine dehydrogenase:Implications for 5-fluorouracil metabolism and toxicity. Proc. Am. Assoc. Cancer Res., 35: 688, 1994.
-
(1994)
Proc. Am. Assoc. Cancer Res.
, vol.35
, pp. 688
-
-
Diasio, R.B.1
-
5
-
-
0027945196
-
Dihydropyrimidine dehydrogenase activity and fluorouracil chemotherapy
-
Diasio, R. B., and Lu, Z-H. Dihydropyrimidine dehydrogenase activity and fluorouracil chemotherapy. J. Clin. Oncol., 12: 2239-2242. 1994
-
(1994)
J. Clin. Oncol.
, vol.12
, pp. 2239-2242
-
-
Diasio, R.B.1
Lu, Z.-H.2
-
6
-
-
0028006858
-
Population study of dihydropyrimidine dehydrogenase in cancer patients
-
Etienne, M. C., Lagrange, J. L., Dassonville, O., Fleming, R., Thyss, A., Renée, N., Schneider, M., Demard, F., and Milano, G. Population study of dihydropyrimidine dehydrogenase in cancer patients. J. Clin. Oncol., 12: 2248-2253, 1994.
-
(1994)
J. Clin. Oncol.
, vol.12
, pp. 2248-2253
-
-
Etienne, M.C.1
Lagrange, J.L.2
Dassonville, O.3
Fleming, R.4
Thyss, A.5
Renée, N.6
Schneider, M.7
Demard, F.8
Milano, G.9
-
8
-
-
0019475570
-
Organic brain syndrome secondary to 5-fluorouracil toxicity
-
Lynch, H. T., Droszcz, C. P., Albano, W. A., and Lynch, J. F. Organic brain syndrome secondary to 5-fluorouracil toxicity. Dis. Colon Rectum, 24: 130-131, 1981.
-
(1981)
Dis. Colon Rectum
, vol.24
, pp. 130-131
-
-
Lynch, H.T.1
Droszcz, C.P.2
Albano, W.A.3
Lynch, J.F.4
-
9
-
-
0028098810
-
Cerebral demyelination with 5 fluorouracil and levamisole
-
Fassas, A. B. T., Gattani, A. M., and Morgello, S. Cerebral demyelination with 5 fluorouracil and levamisole. Cancer Invest., 12: 379-383, 1994
-
(1994)
Cancer Invest.
, vol.12
, pp. 379-383
-
-
Fassas, A.B.T.1
Gattani, A.M.2
Morgello, S.3
-
10
-
-
0017184389
-
Rapid sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford, M. A. Rapid sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72: 258-264, 1976.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 258-264
-
-
Bradford, M.A.1
-
11
-
-
0020451764
-
Rapid catabolism of 5-fluorouracil in freshly isolated hepatocytes as analyzed by high performance liquid chromatography
-
Sommadossi, J. P., Gewirtz, D. A., Diasio, R. B., Aubert, C., Cano, J. P., and Goldman, I. D. Rapid catabolism of 5-fluorouracil in freshly isolated hepatocytes as analyzed by high performance liquid chromatography. J. Biol. Chem., 257: 8171-8176, 1982.
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 8171-8176
-
-
Sommadossi, J.P.1
Gewirtz, D.A.2
Diasio, R.B.3
Aubert, C.4
Cano, J.P.5
Goldman, I.D.6
-
12
-
-
0026793052
-
Purification and characterization of dihydropyrimidine dehydrogenase from human liver
-
Lu, Z-H., Zhang, R., and Diasio, R. B. Purification and characterization of dihydropyrimidine dehydrogenase from human liver. J. Biol. Chem., 267: 17102-17109, 1992.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 17102-17109
-
-
Lu, Z.-H.1
Zhang, R.2
Diasio, R.B.3
-
13
-
-
0019993898
-
Clinical pharmacological studies of concurrent infusion of 5-fluorouracil and thymidine in treatment of colorectal carcinomas
-
Au, J. L., Rustum, Y. M., Ledesma, E. J., Mittelman, A., and Creaven, P. J. Clinical pharmacological studies of concurrent infusion of 5-fluorouracil and thymidine in treatment of colorectal carcinomas. Cancer Res., 42: 2930-2937, 1982.
-
(1982)
Cancer Res.
, vol.42
, pp. 2930-2937
-
-
Au, J.L.1
Rustum, Y.M.2
Ledesma, E.J.3
Mittelman, A.4
Creaven, P.J.5
-
14
-
-
0026699408
-
Gas chromatographic-mass spectrometric method for routine monitoring of 5-fluorouracil in plasma of patients receiving low-level protracted infusions
-
Anderson, L. W., Parker, R. J., Collins, J. M., Ahlgren, J. D., Wilkinson, D., Strong, J. M. Gas chromatographic-mass spectrometric method for routine monitoring of 5-fluorouracil in plasma of patients receiving low-level protracted infusions. J. Chromatog., 581: 195-201, 1992.
-
(1992)
J. Chromatog.
, vol.581
, pp. 195-201
-
-
Anderson, L.W.1
Parker, R.J.2
Collins, J.M.3
Ahlgren, J.D.4
Wilkinson, D.5
Strong, J.M.6
-
15
-
-
9044241006
-
Severe neurotoxicity following 5-fluorouracil (FUra) chemotherapy in patients with dihydropyrimidine dehydrogenase (DPD) deficiency
-
Amin, G., Shahinian, H., Miller, D., Vukelja, S., Zhang, R., Lu, Z., Diasio, R. B. Severe neurotoxicity following 5-fluorouracil (FUra) chemotherapy in patients with dihydropyrimidine dehydrogenase (DPD) deficiency. Proc. Am. Soc. Clin. Oncol., 14: 169, 1995
-
(1995)
Proc. Am. Soc. Clin. Oncol.
, vol.14
, pp. 169
-
-
Amin, G.1
Shahinian, H.2
Miller, D.3
Vukelja, S.4
Zhang, R.5
Lu, Z.6
Diasio, R.B.7
-
16
-
-
0022263834
-
Familial pyrimidinemia and pyriminuria associated with severe fluorouracil toxicity
-
Tuchman, M., Stoeckeler, J S., Kiang, D. T., O'Dea, R. F., Ramnaraine, M. L., and Mirkin, B. L. Familial pyrimidinemia and pyriminuria associated with severe fluorouracil toxicity. N. Engl. J. Med., 313: 245-249, 1985.
-
(1985)
N. Engl. J. Med.
, vol.313
, pp. 245-249
-
-
Tuchman, M.1
Stoeckeler, J.S.2
Kiang, D.T.3
O'Dea, R.F.4
Ramnaraine, M.L.5
Mirkin, B.L.6
-
17
-
-
0027534425
-
Dihydropyrimidine dehydrogenase activity in cancer patients
-
Fleming, R. A., Milano, G. A., Gaspard, M. H., Bargnous, P. J., Thyss, A., Plagne, R., Renée, N., Schneider, M., and Demard, F. Dihydropyrimidine dehydrogenase activity in cancer patients. Eur. J. Cancer, 29A: 740-744, 1993.
-
(1993)
Eur. J. Cancer
, vol.29 A
, pp. 740-744
-
-
Fleming, R.A.1
Milano, G.A.2
Gaspard, M.H.3
Bargnous, P.J.4
Thyss, A.5
Plagne, R.6
Renée, N.7
Schneider, M.8
Demard, F.9
-
18
-
-
0027231509
-
Reversal of 5-fluorouracil-induced toxicity by oral administration of uridine
-
Van Groeningen, C. J., Peters, G. J., and Pinedo, H. M. Reversal of 5-fluorouracil-induced toxicity by oral administration of uridine. Ann. Oncol., 4: 317-320, 1993.
-
(1993)
Ann. Oncol.
, vol.4
, pp. 317-320
-
-
Van Groeningen, C.J.1
Peters, G.J.2
Pinedo, H.M.3
-
19
-
-
0025752749
-
Clinical use of thymidine as a rescue agent from methotrexate toxicity
-
Grem, J. L , King, S. A., Sorensen, J. M., and Christian, M. C. Clinical use of thymidine as a rescue agent from methotrexate toxicity. Invest. New Drugs, 9: 281-290, 1991.
-
(1991)
Invest. New Drugs
, vol.9
, pp. 281-290
-
-
Grem, J.L.1
King, S.A.2
Sorensen, J.M.3
Christian, M.C.4
-
20
-
-
0014834207
-
Biochemical basis for fluorouracil neurotoxicity: The role of Krebs cycle inhibition by fluoroacetate
-
Koenig, H., and Patel, A. Biochemical basis for fluorouracil neurotoxicity: the role of Krebs cycle inhibition by fluoroacetate Arch. Neurol., 23: 155-160, 1970.
-
(1970)
Arch. Neurol.
, vol.23
, pp. 155-160
-
-
Koenig, H.1
Patel, A.2
|