-
1
-
-
0021843777
-
Dominant inheritance of adenomatous colonic polyps and colorectal cancer
-
Burt RW, Bishop DT, Cannon LA, Dowdle MA, Lee RG, Skolnick MH. Dominant inheritance of adenomatous colonic polyps and colorectal cancer. N Engl J Med 1985;312:1540-4.
-
(1985)
N Engl J Med
, vol.312
, pp. 1540-1544
-
-
Burt, R.W.1
Bishop, D.T.2
Cannon, L.A.3
Dowdle, M.A.4
Lee, R.G.5
Skolnick, M.H.6
-
2
-
-
0027248156
-
Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer
-
Lynch HT, Smyrk TC, Watson P, Lanspa SJ, Lynch JF, Lynch PM, Cavalicri RJ, Boland CR. Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer. Gastroenterology 1993;104:1535-49.
-
(1993)
Gastroenterology
, vol.104
, pp. 1535-1549
-
-
Lynch, H.T.1
Smyrk, T.C.2
Watson, P.3
Lanspa, S.J.4
Lynch, J.F.5
Lynch, P.M.6
Cavalicri, R.J.7
Boland, C.R.8
-
3
-
-
0025938038
-
Identification and characterization of the familial adenomatous polyposis coli gene
-
Groden J, Thliveris A, Samowitz W, Carison M, Gelbert L, Albertsen H, Joslyn G, Stevens J, Spirio L, Robertson M, Sargeant L, Krapcho K, et al. Identification and characterization of the familial adenomatous polyposis coli gene. Cell 1991;66:589-600.
-
(1991)
Cell
, vol.66
, pp. 589-600
-
-
Groden, J.1
Thliveris, A.2
Samowitz, W.3
Carison, M.4
Gelbert, L.5
Albertsen, H.6
Joslyn, G.7
Stevens, J.8
Spirio, L.9
Robertson, M.10
Sargeant, L.11
Krapcho, K.12
-
4
-
-
0025817880
-
Identification of FAP locus genes from chromosome 5q21
-
Kinzler KW, Nilbert MC, Su L-K, Vogelstein B, Bryan TM, Levy DB, Smith KJ, Preisinger AC, Hedge P, McKechnie D, Finniear R, Markham A, et al. Identification of FAP locus genes from chromosome 5q21. Science 1991;253:661-5.
-
(1991)
Science
, vol.253
, pp. 661-665
-
-
Kinzler, K.W.1
Nilbert, M.C.2
Su, L.-K.3
Vogelstein, B.4
Bryan, T.M.5
Levy, D.B.6
Smith, K.J.7
Preisinger, A.C.8
Hedge, P.9
McKechnie, D.10
Finniear, R.11
Markham, A.12
-
5
-
-
0027742295
-
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
-
Fishel R, Lescoe MK, Rao MRS, Copeland NG, Jenkins NA, Garber J, Kane M, Kolodner R. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993;75:1027-38.
-
(1993)
Cell
, vol.75
, pp. 1027-1038
-
-
Fishel, R.1
Lescoe, M.K.2
Rao, M.R.S.3
Copeland, N.G.4
Jenkins, N.A.5
Garber, J.6
Kane, M.7
Kolodner, R.8
-
6
-
-
0028221943
-
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer
-
Bronner CE, Baker SM, Morrison PT, Warren G, Smith LG, Lescoe MK, Kane M, Earabino C, Lipford J, Lindblom A, Tannergard P, Bollag RJ, et al. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 1994;368:258-61.
-
(1994)
Nature
, vol.368
, pp. 258-261
-
-
Bronner, C.E.1
Baker, S.M.2
Morrison, P.T.3
Warren, G.4
Smith, L.G.5
Lescoe, M.K.6
Kane, M.7
Earabino, C.8
Lipford, J.9
Lindblom, A.10
Tannergard, P.11
Bollag, R.J.12
-
7
-
-
0031278322
-
Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer
-
Miyaki M, Konishi M, Tanaka K, Kikuchi-Yanoshita R, Muraoka M, Yasuno M, Igari T, Koike M, Chiba M, Mori T. Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer. Nat Genet 1997;17:271-2.
-
(1997)
Nat Genet
, vol.17
, pp. 271-272
-
-
Miyaki, M.1
Konishi, M.2
Tanaka, K.3
Kikuchi-Yanoshita, R.4
Muraoka, M.5
Yasuno, M.6
Igari, T.7
Koike, M.8
Chiba, M.9
Mori, T.10
-
8
-
-
0027933070
-
Mutation of two PMS homologues in hereditary nonpolyposis colon cancer
-
Nicolaides NC, Papadopoulos N, Liu B, Wei Y-F, Carter KC, Ruben SM, Rosen CA, Haseltine WA, Fleishmann RD, Fraser CM, Adams MD, Venter JC, et al. Mutation of two PMS homologues in hereditary nonpolyposis colon cancer. Nature 1994;371:75-80.
-
(1994)
Nature
, vol.371
, pp. 75-80
-
-
Nicolaides, N.C.1
Papadopoulos, N.2
Liu, B.3
Wei, Y.-F.4
Carter, K.C.5
Ruben, S.M.6
Rosen, C.A.7
Haseltine, W.A.8
Fleishmann, R.D.9
Fraser, C.M.10
Adams, M.D.11
Venter, J.C.12
-
9
-
-
11144358645
-
High frequency of mutations of the PIK3CA gene in human cancers
-
Samuels Y, Wang Z, Bardelli A, Silliman N, Ptak J, Szabo S, Yan H, Gazdar A, Powell SM, Riggins GJ, Willson JK, Markowitz S, et al. High frequency of mutations of the PIK3CA gene in human cancers. Science 2004;304:554.
-
(2004)
Science
, vol.304
, pp. 554
-
-
Samuels, Y.1
Wang, Z.2
Bardelli, A.3
Silliman, N.4
Ptak, J.5
Szabo, S.6
Yan, H.7
Gazdar, A.8
Powell, S.M.9
Riggins, G.J.10
Willson, J.K.11
Markowitz, S.12
-
10
-
-
7444250290
-
Mutation of the PIK3CA gene in ovarian and breast cancer
-
Campbell IG, Russell SE, Choong DYH, Montgomery KG, Ciavarella ML, Hooi CSF, Cristiano BE, Pearson RB, Phillips WA. Mutation of the PIK3CA gene in ovarian and breast cancer. Cancer Res 2004;64:7678-7681.
-
(2004)
Cancer Res
, vol.64
, pp. 7678-7681
-
-
Campbell, I.G.1
Russell, S.E.2
Choong, D.Y.H.3
Montgomery, K.G.4
Ciavarella, M.L.5
Hooi, C.S.F.6
Cristiano, B.E.7
Pearson, R.B.8
Phillips, W.A.9
-
11
-
-
22144452507
-
The prevalence of PIK3CA mutations in gastric and colon cancer
-
Velho S, Oliverira C, Ferreira A, Ferreira AC, Suriano G, Schwartz S, Jr, Duval A, Carneiro F, Machado JC, Hamelin R, Seruca R. The prevalence of PIK3CA mutations in gastric and colon cancer. Eur J Cancer 2005;41:1649-54.
-
(2005)
Eur J Cancer
, vol.41
, pp. 1649-1654
-
-
Velho, S.1
Oliverira, C.2
Ferreira, A.3
Ferreira, A.C.4
Suriano, G.5
Schwartz Jr, S.6
Duval, A.7
Carneiro, F.8
Machado, J.C.9
Hamelin, R.10
Seruca, R.11
-
12
-
-
22144491262
-
Mutations of PIK3CA in gastric adenocarcinoma
-
Li SWV, Wong CW, Chan TL, Chan ASW, Zhao W, Chu K-M, So S, Chen X, Yuen ST, Leung SY. Mutations of PIK3CA in gastric adenocarcinoma. BMC Cancer 2005;5:29.
-
(2005)
BMC Cancer
, vol.5
, pp. 29
-
-
Li, S.W.V.1
Wong, C.W.2
Chan, T.L.3
Chan, A.S.W.4
Zhao, W.5
Chu, K.-M.6
So, S.7
Chen, X.8
Yuen, S.T.9
Leung, S.Y.10
-
13
-
-
20044388328
-
PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas
-
Lee JW, Soung YH, Kim SY, Lee HW, Park WS, Nam SW, Kim SH, Lee JY, Yoo NJ, Lee SH. PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas. Oncogene 2005;24:1477-80.
-
(2005)
Oncogene
, vol.24
, pp. 1477-1480
-
-
Lee, J.W.1
Soung, Y.H.2
Kim, S.Y.3
Lee, H.W.4
Park, W.S.5
Nam, S.W.6
Kim, S.H.7
Lee, J.Y.8
Yoo, N.J.9
Lee, S.H.10
-
14
-
-
3442878125
-
Mutation of PIK3CA in anaplastic oligodenderogliornas, high-grade astrocytomas, and meduloblastomas
-
Broderick DK, Di C, Parrett TJ, Samuels YR, Cummins JM, McLendon RE, Fults DW, Velculescu VE, Bigner DD, Yan H. Mutation of PIK3CA in anaplastic oligodenderogliornas, high-grade astrocytomas, and meduloblastomas. Cancer Res 2004;64:5048-50.
-
(2004)
Cancer Res
, vol.64
, pp. 5048-5050
-
-
Broderick, D.K.1
Di, C.2
Parrett, T.J.3
Samuels, Y.R.4
Cummins, J.M.5
McLendon, R.E.6
Fults, D.W.7
Velculescu, V.E.8
Bigner, D.D.9
Yan, H.10
-
15
-
-
17144382038
-
Frequent mutation of the PIK3CA gene in ovarian and breast cancer
-
Levine DA, Bogomolniy F, Yee CJ, Lash A, Barakat RR, Borgen PI, Boyd J. Frequent mutation of the PIK3CA gene in ovarian and breast cancer. Clin Cancer Res 2005;11:2875-8.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2875-2878
-
-
Levine, D.A.1
Bogomolniy, F.2
Yee, C.J.3
Lash, A.4
Barakat, R.R.5
Borgen, P.I.6
Boyd, J.7
-
16
-
-
28544452359
-
Mutation of the PIK3CA gene in anaplastic thyroid cancer
-
Garcia-Rostan G, Costa AM, Pereira-Castro I, Salvatore G, Hernandez R, Hermsem MJA, Herrero A, Fusco A, Cameselle-Teijeiro J, Santoro M. Mutation of the PIK3CA gene in anaplastic thyroid cancer. Cancer Res 2005;65:10199-207.
-
(2005)
Cancer Res
, vol.65
, pp. 10199-10207
-
-
Garcia-Rostan, G.1
Costa, A.M.2
Pereira-Castro, I.3
Salvatore, G.4
Hernandez, R.5
Hermsem, M.J.A.6
Herrero, A.7
Fusco, A.8
Cameselle-Teijeiro, J.9
Santoro, M.10
-
17
-
-
0028601306
-
Molecular cloning, cDNA sequence, and chromosomal localization of the human phosphatidylinositol 3-kinase p100α (P1K3CA) gene
-
Volinia S, Hiles I, Ormondroyd E, Nizetic D, Antonacci R, Rocchi M, Wterfield MD. Molecular cloning, cDNA sequence, and chromosomal localization of the human phosphatidylinositol 3-kinase p100α (P1K3CA) gene. Genomics 1994;24:472-7.
-
(1994)
Genomics
, vol.24
, pp. 472-477
-
-
Volinia, S.1
Hiles, I.2
Ormondroyd, E.3
Nizetic, D.4
Antonacci, R.5
Rocchi, M.6
Wterfield, M.D.7
-
18
-
-
0037205048
-
The phosphoinositide 3-kinase pathway
-
Cantley LC. The phosphoinositide 3-kinase pathway. Science 2002;296:1655-57.
-
(2002)
Science
, vol.296
, pp. 1655-1657
-
-
Cantley, L.C.1
-
19
-
-
20444374445
-
Mutant PIK3CA promotes cell growth and invasion of human cancer cells
-
Samuels Y, Diaz LA, Schmidt-Kittler O, Cummins JM, DeLong L, Cheong I, Rago C, Huso DL, Lengauer C, Kinzler KW, Vogelstein B, Velculescu VE. Mutant PIK3CA promotes cell growth and invasion of human cancer cells. Cancer Cell 2005;7:561-73.
-
(2005)
Cancer Cell
, vol.7
, pp. 561-573
-
-
Samuels, Y.1
Diaz, L.A.2
Schmidt-Kittler, O.3
Cummins, J.M.4
DeLong, L.5
Cheong, I.6
Rago, C.7
Huso, D.L.8
Lengauer, C.9
Kinzler, K.W.10
Vogelstein, B.11
Velculescu, V.E.12
-
20
-
-
14144252004
-
Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic
-
Kang S, Bader AG, Vogt PK. Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. Proc Natl Acad Sci USA 2005;102:802-807.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 802-807
-
-
Kang, S.1
Bader, A.G.2
Vogt, P.K.3
-
21
-
-
21144457217
-
Functional analysis of PIK3CA gene mutations in human colorectal cancer
-
Ikenoue T, Kanai F, Hikiba Y, Obata T, Tanaka Y, Imamura J, Ohta M, Jazag A, Guleng B, Tateishi K, Asaoka Y, Matsumura M, et al. Functional analysis of PIK3CA gene mutations in human colorectal cancer. Cancer Res 2005;65:4562-67.
-
(2005)
Cancer Res
, vol.65
, pp. 4562-4567
-
-
Ikenoue, T.1
Kanai, F.2
Hikiba, Y.3
Obata, T.4
Tanaka, Y.5
Imamura, J.6
Ohta, M.7
Jazag, A.8
Guleng, B.9
Tateishi, K.10
Asaoka, Y.11
Matsumura, M.12
-
22
-
-
31944444234
-
Cancer-specific mutations in PIK3CA are oncogenic in vivo
-
Bader AG, Kang S, Vogt PK. Cancer-specific mutations in PIK3CA are oncogenic in vivo. Proc Natl Acad Sci USA 2006;103:1475-9.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1475-1479
-
-
Bader, A.G.1
Kang, S.2
Vogt, P.K.3
-
23
-
-
0031407606
-
Spectra of spontaneous mutations at the hprt locus in colorectal carcinoma cell lines defective in mismatch repair
-
Ozeki S, Tachibana A, Tatsumi K, Kato T. Spectra of spontaneous mutations at the hprt locus in colorectal carcinoma cell lines defective in mismatch repair. Carcinogenesis 1997;18:1127-33.
-
(1997)
Carcinogenesis
, vol.18
, pp. 1127-1133
-
-
Ozeki, S.1
Tachibana, A.2
Tatsumi, K.3
Kato, T.4
-
24
-
-
0032481027
-
Specificity of mutations in the PMS2-deficient human tumor cell line HEC-1-A
-
Kato T, Yatagai F, Glickman BW, Tachibana A, Ikenaga M. Specificity of mutations in the PMS2-deficient human tumor cell line HEC-1-A. Mut Res 1998;422:279-83.
-
(1998)
Mut Res
, vol.422
, pp. 279-283
-
-
Kato, T.1
Yatagai, F.2
Glickman, B.W.3
Tachibana, A.4
Ikenaga, M.5
-
25
-
-
0033568145
-
Frequent mutation of β-catenin and APC genes in primary colorectal tumors from patients with hereditary nonpolyposis colorectal cancer
-
Miyaki M, Iijima T, Kimura J, Yasuno M, Mori T, Hayashi Y, Koike M, Shitara N, Iwama T, Kuroki T. Frequent mutation of β-catenin and APC genes in primary colorectal tumors from patients with hereditary nonpolyposis colorectal cancer. Cancer Res 1999;59:4506-9.
-
(1999)
Cancer Res
, vol.59
, pp. 4506-4509
-
-
Miyaki, M.1
Iijima, T.2
Kimura, J.3
Yasuno, M.4
Mori, T.5
Hayashi, Y.6
Koike, M.7
Shitara, N.8
Iwama, T.9
Kuroki, T.10
-
26
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein B, Kinzler KW. Cancer genes and the pathways they control. Nat Med 2004;10:789-99.
-
(2004)
Nat Med
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
27
-
-
0025241292
-
Genetic changes and histopatological types in colorectal tumors from patients with familial adenomatous polyposis
-
Miyaki M, Seki M, Okamoto M, Yamanaka A, Maeda Y, Tanaka K, Kikuchi R, Iwama T, Ikeuchi T, Tonomura A, Nakamura Y, White R, et al. Genetic changes and histopatological types in colorectal tumors from patients with familial adenomatous polyposis. Cancer Res 1990;50:7166-73.
-
(1990)
Cancer Res
, vol.50
, pp. 7166-7173
-
-
Miyaki, M.1
Seki, M.2
Okamoto, M.3
Yamanaka, A.4
Maeda, Y.5
Tanaka, K.6
Kikuchi, R.7
Iwama, T.8
Ikeuchi, T.9
Tonomura, A.10
Nakamura, Y.11
White, R.12
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