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Volumn 7, Issue 3, 2000, Pages 193-198

Relation between thymidylate synthase expression and survival in colon carcinoma, and determination of appropriate application of 5-fluorouracil by immunohistochemical method

Author keywords

5 Fluorouracil; Colon carcinoma; Immunohistochemistry; Thymidylate synthase

Indexed keywords

ANTINEOPLASTIC AGENT; FLUOROURACIL; THYMIDYLATE SYNTHASE;

EID: 0033995850     PISSN: 10689265     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02523653     Document Type: Article
Times cited : (86)

References (30)
  • 1
    • 0028940399 scopus 로고
    • Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors
    • Johnston PG, Lenz HJ, Leichman CG, et al. Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors. Cancer Res 1995;55:1407-12.
    • (1995) Cancer Res , vol.55 , pp. 1407-1412
    • Johnston, P.G.1    Lenz, H.J.2    Leichman, C.G.3
  • 2
    • 0030847561 scopus 로고    scopus 로고
    • Chemotherapy for the treatment of patients with metastatic colorectal cancer: An overview
    • Isacoff WH, Borud K. Chemotherapy for the treatment of patients with metastatic colorectal cancer: an overview. World J Surg 1997;21:748-62.
    • (1997) World J Surg , vol.21 , pp. 748-762
    • Isacoff, W.H.1    Borud, K.2
  • 3
    • 0029054492 scopus 로고
    • The effect of dose and interval between 5-fluorouracil and leucovorin on the formation of thymidylate synthase ternary complex in human cancer cells
    • Drake JC, Voeller DM, Allegra CJ, Johnston PG. The effect of dose and interval between 5-fluorouracil and leucovorin on the formation of thymidylate synthase ternary complex in human cancer cells. Br J Cancer 1995;71:1145-50.
    • (1995) Br J Cancer , vol.71 , pp. 1145-1150
    • Drake, J.C.1    Voeller, D.M.2    Allegra, C.J.3    Johnston, P.G.4
  • 4
    • 0023111335 scopus 로고
    • Thymidylate synthase gene amplification in a colon tumor resistant to fluoropyrimidine chemotherapy
    • Clark JL, Berger SH, Mittelman A, Berger FG. Thymidylate synthase gene amplification in a colon tumor resistant to fluoropyrimidine chemotherapy. Cancer Treat Rep 1987;71:261-5.
    • (1987) Cancer Treat Rep , vol.71 , pp. 261-265
    • Clark, J.L.1    Berger, S.H.2    Mittelman, A.3    Berger, F.G.4
  • 6
    • 0028019880 scopus 로고
    • Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: Implications for treatment with fluorouracil
    • Peters GJ, van der Wilt CL, van Groeningen CJ, Smid K, Meijer S, Pinedo HM. Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: implications for treatment with fluorouracil. J Clin Oncol 1994; 12:2035-42.
    • (1994) J Clin Oncol , vol.12 , pp. 2035-2042
    • Peters, G.J.1    Van Der Wilt, C.L.2    Van Groeningen, C.J.3    Smid, K.4    Meijer, S.5    Pinedo, H.M.6
  • 7
    • 0030883708 scopus 로고    scopus 로고
    • Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin
    • Leichman CG, Lenz HJ, Leichman L, et al. Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin. J Clin Oncol 1997;15:3223-9.
    • (1997) J Clin Oncol , vol.15 , pp. 3223-3229
    • Leichman, C.G.1    Lenz, H.J.2    Leichman, L.3
  • 8
    • 0031014682 scopus 로고    scopus 로고
    • Thymidylate synthase inhibitors in cancer therapy: Direct and indirect inhibitors
    • Rustum YM, Harstrick A, Cao S, et al. Thymidylate synthase inhibitors in cancer therapy: direct and indirect inhibitors. J Clin Oncol 1997;15:389-400.
    • (1997) J Clin Oncol , vol.15 , pp. 389-400
    • Rustum, Y.M.1    Harstrick, A.2    Cao, S.3
  • 9
    • 0027172496 scopus 로고
    • The modulation by L-leucovorin of 5-fluorouracil antitumor activity on human colon carcinoma cells in vitro and in vivo
    • Kase S, Kubota T, Watanabe M, et al. The modulation by L-leucovorin of 5-fluorouracil antitumor activity on human colon carcinoma cells in vitro and in vivo. Surg Today 1993;23:615-20.
    • (1993) Surg Today , vol.23 , pp. 615-620
    • Kase, S.1    Kubota, T.2    Watanabe, M.3
  • 10
    • 0029039255 scopus 로고
    • Addition of leucovorin in modulation of 5-fluorouracil with methotrexate: Potentiating or reversing effect?
    • Van der Wilt CL, Braakhuis BJ, Pinedo HM, De Jong M, Smid K, Peters GJ. Addition of leucovorin in modulation of 5-fluorouracil with methotrexate: potentiating or reversing effect? Int J Cancer 1995; 61:672-8.
    • (1995) Int J Cancer , vol.61 , pp. 672-678
    • Van Der Wilt, C.L.1    Braakhuis, B.J.2    Pinedo, H.M.3    De Jong, M.4    Smid, K.5    Peters, G.J.6
  • 11
    • 0028888329 scopus 로고
    • Aberrant cell cycle inhibition pattern in human colon carcinoma cell lines after exposure to 5-fluorouracil
    • Pizzorno G, Sun Z, Handschumacher RE. Aberrant cell cycle inhibition pattern in human colon carcinoma cell lines after exposure to 5-fluorouracil. Biochem Pharmacol 1995;49:553-7.
    • (1995) Biochem Pharmacol , vol.49 , pp. 553-557
    • Pizzorno, G.1    Sun, Z.2    Handschumacher, R.E.3
  • 12
    • 0028151449 scopus 로고
    • The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer
    • Johnston PG, Fisher ET, Rockette HE, et al. The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer. J Clin Oncol 1994; 12:2640-7.
    • (1994) J Clin Oncol , vol.12 , pp. 2640-2647
    • Johnston, P.G.1    Fisher, E.T.2    Rockette, H.E.3
  • 13
    • 0032080712 scopus 로고    scopus 로고
    • High expression of thymidylate synthase is associated with the drug resistance of gastric carcinoma to high dose 5-fluorouracil-based systemic chemotherapy
    • Yeh KH, Shun CT, Chen CL, et al. High expression of thymidylate synthase is associated with the drug resistance of gastric carcinoma to high dose 5-fluorouracil-based systemic chemotherapy. Cancer 1998;82:1626-31.
    • (1998) Cancer , vol.82 , pp. 1626-1631
    • Yeh, K.H.1    Shun, C.T.2    Chen, C.L.3
  • 14
    • 0031832182 scopus 로고    scopus 로고
    • Thymidylate synthase expression and activity: Relation to S-phase parameters and 5-fluorouracil sensitivity
    • Mirjolet JF, Barberi Heyob M, et al. Thymidylate synthase expression and activity: relation to S-phase parameters and 5-fluorouracil sensitivity. Br J Cancer 1998;78:62-8.
    • (1998) Br J Cancer , vol.78 , pp. 62-68
    • Mirjolet, J.F.1    Barberi Heyob, M.2
  • 15
    • 0029095796 scopus 로고
    • Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: Preliminary report from an ongoing trial
    • Leichman L, Lenz HJ, Leichman CG, et al. Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: preliminary report from an ongoing trial. Eur J Cancer 1995;31A:1306-10.
    • (1995) Eur J Cancer , vol.31 A , pp. 1306-1310
    • Leichman, L.1    Lenz, H.J.2    Leichman, C.G.3
  • 16
    • 0345973521 scopus 로고    scopus 로고
    • Thymidylate synthase is a predictor for response and resistance in hepatic artery infusion chemotherapy
    • Kornmann M, Link KH, Lenz HJ, et al. Thymidylate synthase is a predictor for response and resistance in hepatic artery infusion chemotherapy. Cancer Lett 1997;118:29-35.
    • (1997) Cancer Lett , vol.118 , pp. 29-35
    • Kornmann, M.1    Link, K.H.2    Lenz, H.J.3
  • 18
    • 0020056302 scopus 로고
    • In vivo kinetics of thymidylate synthase inhibition in 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas
    • Spears CP, Shahinian AH, Moran RG, Heidelberger C, Corbett TH. In vivo kinetics of thymidylate synthase inhibition in 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas. Cancer Res 1982;42:450-6.
    • (1982) Cancer Res , vol.42 , pp. 450-456
    • Spears, C.P.1    Shahinian, A.H.2    Moran, R.G.3    Heidelberger, C.4    Corbett, T.H.5
  • 19
    • 15444349773 scopus 로고    scopus 로고
    • p53 and thymidylate synthase expression in untreated stage II colon cancer: Associations with recurrence, survival, and site
    • Lenz HJ, Danenberg KD, Leichman CG, et al. p53 and thymidylate synthase expression in untreated stage II colon cancer: associations with recurrence, survival, and site. Clin Cancer Res 1998;4:1227-34.
    • (1998) Clin Cancer Res , vol.4 , pp. 1227-1234
    • Lenz, H.J.1    Danenberg, K.D.2    Leichman, C.G.3
  • 20
    • 0029021602 scopus 로고
    • Increased thymidylate synthase protein levels are principally associated with proliferation but not cell cycle phase in asynchronous human cancer cells
    • Pestalozzi BC, McGinn CJ, Kinsella TJ, et al. Increased thymidylate synthase protein levels are principally associated with proliferation but not cell cycle phase in asynchronous human cancer cells. Br J Cancer 1995;71:1151-7.
    • (1995) Br J Cancer , vol.71 , pp. 1151-1157
    • Pestalozzi, B.C.1    McGinn, C.J.2    Kinsella, T.J.3
  • 21
    • 0031941249 scopus 로고    scopus 로고
    • A new prognostic factor for colorectal carcinoma, thymidylate synthase, and its therapeutic significance
    • Yamachika T, Nakanishi H, Inada K, et al. A new prognostic factor for colorectal carcinoma, thymidylate synthase, and its therapeutic significance. Cancer 1998;82:70-7.
    • (1998) Cancer , vol.82 , pp. 70-77
    • Yamachika, T.1    Nakanishi, H.2    Inada, K.3
  • 23
    • 0028006858 scopus 로고
    • Population study of dihydropyrimidine dehydrogenase in cancer patients
    • Etienne MC, Lagrange JL, Dassonville O, et al. Population study of dihydropyrimidine dehydrogenase in cancer patients. J Clin Oncol 1994;12:2248-53.
    • (1994) J Clin Oncol , vol.12 , pp. 2248-2253
    • Etienne, M.C.1    Lagrange, J.L.2    Dassonville, O.3
  • 24
    • 0028097137 scopus 로고
    • A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil
    • Beck A, Etienne MC, Cheadame S, et al. A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil. Eur J Cancer 1994;30A:1517-22.
    • (1994) Eur J Cancer , vol.30 A , pp. 1517-1522
    • Beck, A.1    Etienne, M.C.2    Cheadame, S.3
  • 25
    • 0028982820 scopus 로고
    • Response to fluorouracil therapy in cancer patients: The role of tumoral dihydropyrimidine dehydrogenase activity
    • Etienne MC, Cheadame S, Fischel JL, et al. Response to fluorouracil therapy in cancer patients: the role of tumoral dihydropyrimidine dehydrogenase activity. J Clin Oncol 1995;13:1663-70.
    • (1995) J Clin Oncol , vol.13 , pp. 1663-1670
    • Etienne, M.C.1    Cheadame, S.2    Fischel, J.L.3
  • 26
    • 0031876466 scopus 로고    scopus 로고
    • Putative role of dihydropyrimidine dehydrogenase in the toxic side effect of 5-fluorouracil in colorectal cancer patients
    • Katona C, Kralovánszky J, Rosta A, et al. Putative role of dihydropyrimidine dehydrogenase in the toxic side effect of 5-fluorouracil in colorectal cancer patients. Oncology 1998;55:468-74.
    • (1998) Oncology , vol.55 , pp. 468-474
    • Katona, C.1    Kralovánszky, J.2    Rosta, A.3
  • 27
    • 0031973816 scopus 로고    scopus 로고
    • Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours
    • McLeod HL, Sludden J, Murray GI, et al. Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours. Br J Cancer 1998;77:461-5.
    • (1998) Br J Cancer , vol.77 , pp. 461-465
    • McLeod, H.L.1    Sludden, J.2    Murray, G.I.3
  • 28
    • 0029918519 scopus 로고    scopus 로고
    • Analysis of the dihydropyrimidine dehydrogenase polymorphism in a British population
    • McMurrough J, McLeod HL. Analysis of the dihydropyrimidine dehydrogenase polymorphism in a British population. Br J Clin Pharmacol 1996;41:425-7.
    • (1996) Br J Clin Pharmacol , vol.41 , pp. 425-427
    • McMurrough, J.1    McLeod, H.L.2
  • 29
    • 0031912432 scopus 로고    scopus 로고
    • Decreased dihydropyrimidine dehydrogenase activity in a population of patients with breast cancer: Implication for 5-fluorouracil-based chemotherapy
    • Lu Z, Zhang R, Carpenter JT, Diasio RB. Decreased dihydropyrimidine dehydrogenase activity in a population of patients with breast cancer: implication for 5-fluorouracil-based chemotherapy. Clin Cancer Res 1998;4:325-9.
    • (1998) Clin Cancer Res , vol.4 , pp. 325-329
    • Lu, Z.1    Zhang, R.2    Carpenter, J.T.3    Diasio, R.B.4
  • 30
    • 15144351973 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase pharmacogenetics in patients with colorectal cancer
    • Ridge SA, Sludden J, Wei X, et al. Dihydropyrimidine dehydrogenase pharmacogenetics in patients with colorectal cancer. Br J Cancer 1998;77:497-500.
    • (1998) Br J Cancer , vol.77 , pp. 497-500
    • Ridge, S.A.1    Sludden, J.2    Wei, X.3


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